股本结构
单位：万股
| 公告日期 | 2025-11-05 | 2025-11-05 | 2025-08-07 | 2025-08-07 | 2025-05-08 | 2025-05-08 |
|---|---|---|---|---|---|---|
| 证券总股本 | 5782.29 | 5777.60 | 5545.89 | 5537.12 | 5510.67 | 5506.69 |
| 普通股本 | 5782.29 | 5777.60 | 5545.89 | 5537.12 | 5510.67 | 5506.69 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-10-31 | 2025-09-30 | 2025-08-01 | 2025-06-30 | 2025-05-02 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-11-05 | 5782.29 | 未披露 | 定期报告 | 2025-10-31 |
| 2025-11-05 | 5777.60 | 未披露 |
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From June 30, 2025 to September 30, 2025
Issuance of common stock in offerings, net of issuance costs
Exercise of stock options
Issuance of common stock from vesting of restricted stock units
|
2025-09-30 |
| 2025-08-07 | 5545.89 | 未披露 | 定期报告 | 2025-08-01 |
| 2025-08-07 | 5537.12 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Exercise of stock options
Issuance of common stock from vesting of restricted stock
Issuance of common stock in offerings, net of issuance costs
Issuance of common stock pursuant to employee stock purchase plan
|
2025-06-30 |
| 2025-05-08 | 5510.67 | 未披露 | 定期报告 | 2025-05-02 |
| 2025-04-17 | 5507.27 | 未披露 | 定期报告 | 2025-04-04 |
| 2025-05-08 | 5506.69 | 未披露 |
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From December 31, 2024 to March 31, 2025
Exercise of stock options
Issuance of common stock from vesting of restricted stock
|
2025-03-31 |
| 2025-02-27 | 5494.40 | 未披露 | 定期报告 | 2025-02-21 |
| 2025-02-27 | 5429.36 | 未披露 |
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From December 31, 2023 to December 31, 2024
Issuance of common stock from vesting of restricted stock
Exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
|
2024-12-31 |
| 2024-11-07 | 5407.47 | 未披露 | 定期报告 | 2024-11-01 |
| 2024-11-07 | 5399.50 | 未披露 |
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From June 30, 2024 to September 30, 2024
Exercise of stock options
Issuance of common stock from vesting of restricted stock
|
2024-09-30 |
| 2024-08-08 | 5375.57 | 未披露 | 定期报告 | 2024-08-02 |
| 2024-08-08 | 5363.11 | 未披露 |
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From March 31, 2024 to June 30, 2024
Issuance of common stock pursuant to employee stock purchase plan
Exercise of stock options
Issuance of common stock from vesting of restricted stock
|
2024-06-30 |
| 2024-05-09 | 5350.26 | 未披露 | 定期报告 | 2024-05-03 |
| 2024-04-11 | 5329.03 | 未披露 | 定期报告 | 2024-04-01 |
| 2024-05-09 | 5328.80 | 未披露 |
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From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock from vesting of restricted stock
|
2024-03-31 |
| 2024-02-28 | 5279.66 | 未披露 | 定期报告 | 2024-02-23 |
| 2024-02-28 | 5228.01 | 未披露 |
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From December 31, 2022 to December 31, 2023
Issuance of common stock to related party
Issuance of common stock from vesting of restricted stock
Exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
|
2023-12-31 |
| 2023-11-13 | 4868.62 | 未披露 | 定期报告 | 2023-11-09 |
| 2023-11-13 | 4867.37 | 未披露 |
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From March 31, 2023 to September 30, 2023
Exercise of stock options
Issuance of common stock from vesting of restricted stock units
|
2023-09-30 |
| 2023-08-14 | 4835.90 | 未披露 | 定期报告 | 2023-08-09 |
| 2023-08-14 | 4831.54 | 未披露 |
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From March 31, 2023 to June 30, 2023
Issuance of common stock upon exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
Issuance of common stock from vesting of restricted stock units
|
2023-06-30 |
| 2023-05-08 | 4799.35 | 未披露 | 定期报告 | 2023-05-04 |
| 2023-05-08 | 4799.00 | 未披露 | 定期报告 | 2023-05-01 |
| 2023-04-28 | 4785.17 | 未披露 | 定期报告 | 2023-04-14 |
| 2023-05-08 | 4784.14 | 未披露 |
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From December 31, 2022 to March 31, 2023
Issuance of common stock in accordance with Gilead Stock Purchase Agreement
Exercise of stock options
Issuance of common stock from vesting of restricted stock
|
2023-03-31 |
| 2023-03-29 | 4784.04 | 未披露 | 定期报告 | 2023-03-28 |
| 2023-03-29 | 4410.60 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Conversion of preferred stock to common stock
Issuance of common stock (initial public offering), net of transaction costs of $15,029
Issuance of common stock (private placement), net of transaction costs of $42
Issuance of common stock (follow-on offering), net of transaction costs of $8,081 Issuance of common stock from
Issuance of common stock from early exercise of restricted stock
Exercise of stock options
|
2022-12-31 |
| 2022-11-14 | 4385.39 | 未披露 | 定期报告 | 2022-11-10 |
| 2022-11-14 | 4384.64 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock from vesting of restricted stock
Exercise of stock options
|
2022-09-30 |
| 2022-08-16 | 4381.92 | 未披露 | 定期报告 | 2022-08-11 |
| 2022-08-16 | 4378.21 | 未披露 |
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From March 31, 2022 to June 30, 2022
Issuance of common stock (follow-on offering), net of transaction costs of $8,081
Issuance of common stock from vesting of restricted stock
|
2022-06-30 |
| 2022-06-21 | 4378.66 | 未披露 |
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1.Common stock offered by 7,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 35,736,584 shares of common stock outstanding as of March 31, 2022
3.The Company also granted the Underwriters an option to purchase up to 1,050,000 shares of the Company’s common stock at the public offering price, less underwriting discounts and commissions, which the Underwriters exercised in full on June 17, 2022.
|
2022-06-21 |
| 2022-05-12 | 3573.66 | 未披露 | 定期报告 | 2022-05-09 |
| 2022-05-12 | 3571.88 | 未披露 |
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From December 31, 2021 to March 31, 2022
Issuance of common stock (initial public offering), net of transaction costs of $15,029
Issuance of common stock (private placement), net of transaction costs of $42
Conversion of preferred stock to common stock
Issuance of common stock from vesting of restricted stock
Exercise of stock options
|
2022-03-31 |
| 2022-03-24 | 3573.66 | 未披露 | 定期报告 | 2022-03-21 |
| 2022-03-24 | 3514.63 | 未披露 | 定期报告 | 2022-03-01 |
| 2022-03-24 | 3478.10 | 未披露 |
更多>>
1.On February 8, 2022, the exercise in full of the underwriters' option to purchase 1,237,500 additional shares of its common stock, at a public offering price of $15.00 per share.
2.The number of shares of common stock to be outstanding after this offering is based on the 33,543,534 shares of common stock outstanding as of February 8, 2022.
|
2022-02-08 |
| 2022-02-07 | 3354.35 | 未披露 |
更多>>
1.Common stock offered by company 8,250,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 25,293,534 shares of common stock outstanding as of September 30, 2021.
|
2022-02-04 |
| 2022-03-24 | 54.42 | 2478.56 |
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From December 31, 2020 to December 31, 2021
Issuance of Series C redeemable convertible preferred stock for cash, net of transaction costs
Issuance of common stock from vesting of restricted stock
Exercise of stock options
|
2021-12-31 |
From June 30, 2025 to September 30, 2025
Issuance of common stock in offerings, net of issuance costs
Exercise of stock options
Issuance of common stock from vesting of restricted stock units
From March 31, 2025 to June 30, 2025
Exercise of stock options
Issuance of common stock from vesting of restricted stock
Issuance of common stock in offerings, net of issuance costs
Issuance of common stock pursuant to employee stock purchase plan
From December 31, 2024 to March 31, 2025
Exercise of stock options
Issuance of common stock from vesting of restricted stock
From December 31, 2023 to December 31, 2024
Issuance of common stock from vesting of restricted stock
Exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
From June 30, 2024 to September 30, 2024
Exercise of stock options
Issuance of common stock from vesting of restricted stock
From March 31, 2024 to June 30, 2024
Issuance of common stock pursuant to employee stock purchase plan
Exercise of stock options
Issuance of common stock from vesting of restricted stock
From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock from vesting of restricted stock
From December 31, 2022 to December 31, 2023
Issuance of common stock to related party
Issuance of common stock from vesting of restricted stock
Exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
From March 31, 2023 to September 30, 2023
Exercise of stock options
Issuance of common stock from vesting of restricted stock units
From March 31, 2023 to June 30, 2023
Issuance of common stock upon exercise of stock options
Issuance of common stock pursuant to employee stock purchase plan
Issuance of common stock from vesting of restricted stock units
From December 31, 2022 to March 31, 2023
Issuance of common stock in accordance with Gilead Stock Purchase Agreement
Exercise of stock options
Issuance of common stock from vesting of restricted stock
From December 31, 2021 to December 31, 2022
Conversion of preferred stock to common stock
Issuance of common stock (initial public offering), net of transaction costs of $15,029
Issuance of common stock (private placement), net of transaction costs of $42
Issuance of common stock (follow-on offering), net of transaction costs of $8,081 Issuance of common stock from
Issuance of common stock from early exercise of restricted stock
Exercise of stock options
From June 30, 2022 to September 30, 2022
Issuance of common stock from vesting of restricted stock
Exercise of stock options
From March 31, 2022 to June 30, 2022
Issuance of common stock (follow-on offering), net of transaction costs of $8,081
Issuance of common stock from vesting of restricted stock
1.Common stock offered by 7,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 35,736,584 shares of common stock outstanding as of March 31, 2022
3.The Company also granted the Underwriters an option to purchase up to 1,050,000 shares of the Company’s common stock at the public offering price, less underwriting discounts and commissions, which the Underwriters exercised in full on June 17, 2022.
From December 31, 2021 to March 31, 2022
Issuance of common stock (initial public offering), net of transaction costs of $15,029
Issuance of common stock (private placement), net of transaction costs of $42
Conversion of preferred stock to common stock
Issuance of common stock from vesting of restricted stock
Exercise of stock options
1.On February 8, 2022, the exercise in full of the underwriters' option to purchase 1,237,500 additional shares of its common stock, at a public offering price of $15.00 per share.
2.The number of shares of common stock to be outstanding after this offering is based on the 33,543,534 shares of common stock outstanding as of February 8, 2022.
1.Common stock offered by company 8,250,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on the 25,293,534 shares of common stock outstanding as of September 30, 2021.
From December 31, 2020 to December 31, 2021
Issuance of Series C redeemable convertible preferred stock for cash, net of transaction costs
Issuance of common stock from vesting of restricted stock
Exercise of stock options