主要股东
注：以下部分股东代表特定权益共同体，直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | Alan H. Auerbach | 否 | 706.21万 | 17.30% | 新增 | 新增 | -- |
| 2 | Janus Henderson Group plc | 是 | 435.56万 | 11.50% | 新增 | 新增 | -- |
| 3 | 领航集团有限公司 | 是 | 261.51万 | 6.90% | 新增 | 新增 | -- |
| 4 | 贝莱德集团公司 | 是 | 238.50万 | 6.30% | 新增 | 新增 | -- |
| 5 | Entities affiliated with OrbiMed Advisors LLC | 是 | 218.45万 | 5.80% | 新增 | 新增 | -- |
| 6 | Entities affiliated with Partner Fund Management, L.P. | 是 | 217.96万 | 5.80% | 新增 | 新增 | -- |
内部人交易
| 日期 | 股东名称 | 变动股数(万股) | 交易后持股数量(万股) | 交易价格 | 是否直接持有 | 内部人类型 |
|---|---|---|---|---|---|---|
| 2025-11-11 | MILLER MICHAEL PATRICK |
|
5.40 | 4.86 | 是 | -- |
| 2025-07-18 | Cesano Alessandra |
|
4.19 | 3.37 | 是 | -- |
| 2025-07-08 | AUERBACH ALAN H |
|
720.25 | 3.53 | 是 | President and CEO |
| 2025-07-08 | AUERBACH ALAN H |
|
718.09 | 3.54 | 是 | President and CEO |
| 2025-07-08 | HUNT DOUGLAS M |
|
16.83 | 3.53 | 是 | Senior Vice President of Regulatory Affairs of the Issuer |
| 2025-07-08 | HUNT DOUGLAS M |
|
16.49 | 3.54 | 是 | Senior Vice President of Regulatory Affairs of the Issuer |
| 2025-07-08 | NOUGUES MAXIMO F |
|
20.82 | 3.53 | 是 | Chief Financial Officer |
| 2025-07-08 | NOUGUES MAXIMO F |
|
20.42 | 3.54 | 是 | Chief Financial Officer |
| 2025-06-13 | Cesano Alessandra |
|
6.89 | 3.40 | 是 | -- |
| 2025-06-13 | Dorval Allison |
|
7.54 | 3.40 | 是 | -- |
| 2025-06-13 | MOYES JAY M |
|
5.33 | 3.40 | 是 | -- |
| 2025-06-13 | Senderowicz Adrian |
|
2.70 | 3.40 | 是 | -- |
| 2025-06-13 | Stuglik Brian M |
|
9.50 | 3.39 | 是 | -- |
| 2025-06-13 | WILSON TROY EDWARD |
|
4.36 | 3.40 | 是 | -- |
| 2025-06-11 | Cesano Alessandra |
|
8.10 | 0.00 | 是 | -- |
| 2025-06-11 | WILSON TROY EDWARD |
|
5.44 | 0.00 | 是 | -- |
| 2025-06-11 | Stuglik Brian M |
|
10.31 | 0.00 | 是 | -- |
| 2025-06-11 | Dorval Allison |
|
8.70 | 0.00 | 是 | -- |
| 2025-06-11 | MOYES JAY M |
|
7.53 | 0.00 | 是 | -- |
| 2025-06-11 | Senderowicz Adrian |
|
5.40 | 0.00 | 是 | -- |
| 2025-06-11 | MILLER MICHAEL PATRICK |
|
7.40 | 0.00 | 是 | -- |
| 2025-02-07 | AUERBACH ALAN H |
|
722.81 | 0.00 | 是 | President and CEO |
| 2025-02-07 | HUNT DOUGLAS M |
|
17.27 | 0.00 | 是 | Senior Vice President of Regulatory Affairs of the Issuer |
| 2025-02-07 | Ludwig Jeffrey Jerome |
|
15.68 | 0.00 | 是 | Chief Commercial Officer |
| 2025-01-02 | AUERBACH ALAN H |
|
702.97 | 3.15 | 是 | President and CEO |
| 2025-01-02 | NOUGUES MAXIMO F |
|
15.23 | 3.15 | 是 | Chief Financial Officer |
| 2025-01-02 | Ludwig Jeffrey Jerome |
|
10.90 | 3.15 | 是 | Chief Commercial Officer |
| 2025-01-02 | HUNT DOUGLAS M |
|
12.46 | 3.15 | 是 | Senior Vice President of Regulatory Affairs of the Issuer |
| 2024-08-12 | MILLER MICHAEL PATRICK |
|
4.70 | 3.49 | 是 | -- |
| 2024-07-17 | AUERBACH ALAN H |
|
706.35 | 3.70 | 是 | President and CEO |
| 2024-07-17 | HUNT DOUGLAS M |
|
13.32 | 3.70 | 是 | Senior Vice President of Regulatory Affairs |
| 2024-07-17 | Ludwig Jeffrey Jerome |
|
11.84 | 3.70 | 是 | Chief Commercial Officer |
| 2024-07-17 | NOUGUES MAXIMO F |
|
16.25 | 3.70 | 是 | Chief Financial Officer |
| 2024-07-02 | AUERBACH ALAN H |
|
708.54 | 3.27 | 是 | President and CEO |
| 2024-07-02 | HUNT DOUGLAS M |
|
13.69 | 3.27 | 是 | Senior Vice President of Regulatory Affairs |
| 2024-07-02 | Ludwig Jeffrey Jerome |
|
12.10 | 3.27 | 是 | Chief Commercial Officer |
| 2024-07-02 | NOUGUES MAXIMO F |
|
16.67 | 3.27 | 是 | Chief Financial Officer |
| 2024-06-18 | Cesano Alessandra |
|
5.40 | 0.00 | 是 | -- |
| 2024-06-18 | MOYES JAY M |
|
4.83 | 0.00 | 是 | -- |
| 2024-06-18 | Dorval Allison |
|
6.00 | 0.00 | 是 | -- |
| 2024-06-18 | MILLER MICHAEL PATRICK |
|
9.54 | 0.00 | 是 | -- |
| 2024-06-18 | Stuglik Brian M |
|
7.61 | 0.00 | 是 | -- |
| 2024-06-18 | WILSON TROY EDWARD |
|
2.74 | 0.00 | 是 | -- |
| 2024-06-18 | Senderowicz Adrian |
|
2.70 | 0.00 | 是 | -- |
| 2024-06-13 | Dorval Allison |
|
3.30 | 3.37 | 是 | -- |
| 2024-06-13 | MOYES JAY M |
|
2.13 | 3.34 | 是 | -- |
| 2024-06-13 | Senderowicz Adrian |
|
-- | 3.33 | 是 | -- |
| 2024-06-13 | Stuglik Brian M |
|
4.91 | 3.39 | 是 | -- |
| 2024-06-13 | WILSON TROY EDWARD |
|
0.04 | 3.33 | 是 | -- |
| 2024-03-15 | AUERBACH ALAN H |
|
710.43 | 0.00 | 是 | President and CEO |
| 2024-02-12 | Ludwig Jeffrey Jerome |
|
12.70 | 0.00 | 是 | Chief Commercial Officer |
| 2024-02-12 | NOUGUES MAXIMO F |
|
17.20 | 0.00 | 是 | Chief Financial Officer |
| 2024-02-12 | AUERBACH ALAN H |
|
709.77 | 0.00 | 是 | President and CEO |
| 2024-02-12 | HUNT DOUGLAS M |
|
14.12 | 0.00 | 是 | The Reporting Person is the Senior Vice President of Regulatory Affairs of the Issuer. |
| 2024-02-12 | Wong Alvin F |
|
14.12 | 0.00 | 是 | Chief Scientific Officer |
| 2024-01-03 | HUNT DOUGLAS M |
|
10.33 | 4.49 | 是 | Senior Vice President of Regulatory Affairs |
| 2024-01-03 | NOUGUES MAXIMO F |
|
12.87 | 4.49 | 是 | Chief Financial Officer |
| 2024-01-03 | AUERBACH ALAN H |
|
693.69 | 4.49 | 是 | President and CEO |
| 2024-01-03 | Ludwig Jeffrey Jerome |
|
10.00 | 4.49 | 是 | Chief Commercial Officer |
| 2024-01-03 | Wong Alvin F |
|
9.82 | 4.49 | 是 | Chief Scientific Officer |