股本结构

单位:万股
公告日期 2026-03-12 2026-02-26 2026-02-26 2025-11-03 2025-11-03 2025-08-11
证券总股本 9542.72 8319.03 8001.08 7727.50 7712.02 7710.58
普通股本 9542.72 8319.03 8001.08 7727.50 7712.02 7710.58
优先股 未披露 未披露 未披露 未披露 未披露 未披露
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2026-03-12 2026-02-23 2025-12-31 2025-10-30 2025-09-30 2025-08-07
注释:中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本(万股) 变动后优先股(万股) 变动原因 变动日期
2026-03-12 9542.72 未披露
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1.Common Stock offered 10,526,317 shares by the company. 2.The underwriters exercised their option to purchase common stock 1,710,526 shares.
2026-03-12
2026-02-26 8319.03 未披露 定期报告 2026-02-23
2026-02-26 8001.08 未披露
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From December 31, 2024 to December 31, 2025 Issuance of common shares pursuant to equity incentive plans Issuance of common shares, net Exercise of warrant
2025-12-31
2025-11-03 7727.50 未披露 定期报告 2025-10-30
2025-11-03 7712.02 未披露
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From June 30, 2025 to September 30, 2025 Issuance of common shares pursuant to equity incentive plans
2025-09-30
2025-08-11 7710.58 未披露 定期报告 2025-08-07
2025-08-11 7693.98 未披露
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From March 31, 2025 to June 30, 2025 Issuance of common shares pursuant to equity incentive plans
2025-06-30
2025-05-12 7673.36 未披露 定期报告 2025-05-08
2025-04-24 7659.36 未披露 定期报告 2025-04-07
2025-05-12 7658.64 未披露
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From December 31, 2024 to March 31, 2025 Issuance of common shares pursuant to equity incentive plans
2025-03-31
2025-02-27 7654.28 未披露 定期报告 2025-02-24
2025-02-27 7641.61 未披露
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From December 31, 2023 to December 31, 2024 Exercise of stock options Issuance of common shares, net
2024-12-31
2024-11-12 7623.96 未披露 定期报告 2024-11-08
2024-11-12 7579.44 未披露
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From June 30, 2024 to September 30, 2024 Issued pursuant to exercise of stock options
2024-09-30
2024-08-08 7576.45 未披露 定期报告 2024-08-05
2024-08-08 7566.76 未披露
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From March 31, 2024 to June 30, 2024 Issued pursuant to exercise of stock options
2024-06-30
2024-05-09 7546.89 未披露 定期报告 2024-05-06
2024-04-26 7546.35 未披露 定期报告 2024-04-05
2024-05-09 7545.97 未披露
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From December 31, 2023 to March 31, 2024 Issued pursuant to exercise of stock options
2024-03-31
2024-02-29 7543.25 未披露 定期报告 2024-02-26
2024-02-29 7537.10 未披露
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From December 31, 2022 to December 31, 2023 Issuance of common shares and pre-funded warrants, net of issuance costs Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
2023-12-31
2023-11-30 7389.13 未披露
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Common shares offered 8,461,542 shares by the company
2023-12-04
2023-11-08 6542.97 未披露 定期报告 2023-11-03
2023-11-08 6500.22 未披露
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From June 30, 2023 to September 30, 2023 Issued pursuant to exercise of stock options Issuance of common shares, net of issuance costs Conversion of pre-funded warrants to common shares
2023-09-30
2023-08-09 6414.55 未披露 定期报告 2023-08-04
2023-08-09 6371.84 未披露
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From March 31, 2023 to June 30, 2023 Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
2023-06-30
2023-05-09 6356.23 未披露 定期报告 2023-05-05
2023-04-27 6312.18 未披露 定期报告 2023-04-04
2023-05-09 6310.70 未披露
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From December 31, 2022 to March 31, 2023 Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
2023-03-31
2023-03-01 6303.80 未披露 定期报告 2023-02-24
2023-03-01 6258.77 未披露
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From December 31, 2021 to December 31, 2022 Issued pursuant to exercise of stock options Issuance of common shares and pre-funded warrants, net of issuance costs Conversion of preferred shares to common shares
2022-12-31
2022-11-08 6254.40 未披露 定期报告 2022-11-04
2022-11-08 6254.25 未披露
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From June 30, 2022 to September 30, 2022 Issued pursuant to exercise of stock options
2022-09-30
2022-08-09 6226.35 未披露 定期报告 2022-08-05
2022-08-09 6224.29 未披露
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From March 31, 2022 to June 30, 2022 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
2022-06-30
2022-06-27 6092.79 未披露
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1.Common shares offered by 7,868,854 shares 2.The number of common shares to be outstanding after this offering is based on 53,059,049 common shares as of March 31, 2022
2022-06-27
2022-05-10 5310.57 未披露 定期报告 2022-05-06
2022-04-28 5307.41 未披露 定期报告 2022-04-05
2022-05-10 5305.90 未披露
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From December 31, 2021 to March 31, 2022 Conversion of preferred shares to common shares Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
2022-03-31
2022-03-01 5192.14 未披露 定期报告 2022-02-25
2022-01-12 5164.53 未披露 定期报告 2022-01-11
2022-03-01 5265.08 101.60
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From December 31, 2020 to December 31, 2021 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
2021-12-31
2021-11-10 5158.93 未披露 定期报告 2021-11-08
2021-10-08 5060.81 未披露
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1.Common shares offered 8,474,577 shares. 2.The number of common shares to be outstanding after this offering is based on 42,133,568 common shares outstanding as of June 30, 2021.
2021-10-08
2021-11-10 4141.29 101.60
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From June 30, 2021 to September 30, 2021 Issued pursuant to exercise of stock options
2021-09-30
2021-08-11 4112.42 未披露 定期报告 2021-08-09
2021-08-11 4111.76 101.60
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From March 31, 2021 to June 30, 2021 Issued pursuant to exercise of stock options
2021-06-30
2021-05-11 4096.72 未披露 定期报告 2021-05-07
2021-04-28 4096.29 101.60 定期报告 2021-04-08
2021-05-11 4096.27 101.60
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From December 31, 2020 to March 31, 2021 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
2021-03-31
2021-03-12 4035.25 未披露
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1.Common shares offered by the company 4,324,325 shares. 2.The number of common shares to be outstanding after this offering is based on 36,028,125 common shares outstanding as of December 31, 2020, which number includes 1,016,000 common shares issuable upon the conversion of 1,016,000 of Series 1 Preferred Shares outstanding as of December 31, 2020.
2021-03-12
2021-03-01 3580.92 未披露 定期报告 2021-02-26
2021-03-01 3501.21 101.60
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From December 31, 2019 to December 31, 2020 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
2020-12-31
2020-11-05 3500.74 未披露 定期报告 2020-11-03
2020-11-05 3499.49 101.60
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from June 30, 2020 to September 30, 2020 Issued pursuant to exercise of stock options
2020-09-30
2020-05-21 3499.49 未披露 定期报告 2020-08-04
2020-08-06 3499.48 101.60
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from March 31, 2020 to June 30, 2020 Issued pursuant to exercise of stock options
2020-06-30
2020-05-21 3497.41 未披露 定期报告 2020-05-18
2020-05-21 3495.63 101.60
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from December 31, 2019 to March 31, 2020 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
2020-03-31
2020-03-09 3495.63 未披露 定期报告 2020-03-05
2020-01-27 3063.46 未披露
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1.Common shares offered by us 3,750,000 common shares 2.The number of common shares to be outstanding after this offering is based on 26,884,594 common shares outstanding as of September 30, 2019
2020-01-27
2020-03-09 2813.92 101.60
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from December 31, 2018 to December 31, 2019 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
2019-12-31
2019-11-05 2586.90 未披露 定期报告 2019-11-01
2019-11-05 2586.86 101.60
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from June 30, 2019 to September 30, 2019 Issued pursuant to exercise of stock options
2019-09-30
2019-08-06 2577.51 101.60
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from March 31, 2019 to June 30,2019 Issued pursuant to exercise of stock options
2019-06-30
2019-05-07 2577.30 未披露 定期报告 2019-05-03
2019-04-29 2577.29 未披露 定期报告 2019-04-08
2019-05-07 2577.20 101.60
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from December 31, 2018 to March 31, 2019 Issued pursuant to exercise of stock options
2019-03-31
2019-03-06 2575.13 未披露 定期报告 2019-03-01
2019-03-06 2575.07 101.60
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from December 31, 2017 to December 31, 2018 Issuance of common shares,net of issuance costs Issued (cancelled) pursuant to exchange agreement Conversion of preferred shares to common shares Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options and warrants
2018-12-31
2018-11-06 2524.03 未披露 定期报告 2018-11-02
2018-11-06 2518.74 156.80
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from December 31, 2017 to September 30, 2018 Issuance of common shares,net of issuance costs Issued (cancelled) pursuant to exchange agreement Conversion of preferred shares to common shares Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options and warrants
2018-09-30
2018-08-07 1926.19 未披露 定期报告 2018-08-03
2018-08-07 1764.10 286.80
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from December 31, 2017 to June 30, 2018 Issued (cancelled) pursuant to exchange agreement Issuance of common shares, net of issuance costs Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options
2018-06-30
2018-05-08 1417.22 未披露 定期报告 2018-05-04
2018-05-08 1417.13 286.80
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from December 31, 2017 to March 28, 2018 Issued (cancelled) pursuant to exchange agreement Cancelled pursuant to termination of collaboration agreement
2018-03-28
2018-03-07 1800.25 未披露 定期报告 2018-03-02
2017-08-03 1799.84 未披露
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from December 31, 2016 to June 30, 2017 Issued pursuant to exercise of stock options
2017-06-30
2017-04-27 1799.67 未披露 定期报告 2017-04-04
2017-05-09 1799.67 未披露
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from December 31, 2016 to March 31, 2017 Issued pursuant to exercise of stock options
2017-03-31
2017-03-08 1793.60 未披露 定期报告 2017-03-03
2017-03-08 1793.06 未披露
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from December 31, 2015 to December 31, 2016 Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
2016-12-31
2016-11-03 1789.33 未披露 定期报告 2016-10-28
2016-11-03 1789.29 未披露
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from December 31, 2015 to September 30, 2016 Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
2016-09-30
2016-08-03 1442.64 未披露 定期报告 2016-07-29
2016-08-03 1441.53 未披露
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from December 31, 2015 to June 30, 2016 Issued pursuant to exercise of stock options
2016-06-30
2016-05-10 1440.39 未披露 定期报告 2016-05-06
2016-05-10 1440.16 未披露
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From December 31, 2015 to March 4, 2016 Issued pursuant to exercise of stock options
2016-03-04
2016-03-08 1438.53 未披露
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from December 31, 2014 to December 31, 2015 Issued pursuant to exercise of stock options
2015-12-31
2015-11-10 1437.62 未披露 定期报告 2015-11-02
2015-11-10 1434.43 未披露
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from December 31, 2014 to September 30, 2015 Issued pursuant to exercise of stock options
2015-09-30
2015-08-13 1428.69 未披露 定期报告 2015-08-07
2015-08-13 1426.72 未披露
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from December 31, 2014 to June 30, 2015 Issued pursuant to exercise of stock options
2015-06-30
2015-05-12 1422.85 未披露 定期报告 2015-05-11
2015-05-12 1422.23 未披露
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from December 31, 2014 to March 31, 2015 Issued pursuant to exercise of stock options
2015-03-31
2015-03-12 1422.16 未披露 定期报告 2015-03-09
2015-03-12 1418.13 未披露
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From December 31, 2013 to December 31, 2014 Conversion of Series A, B and E convertible preferred shares Issuance of common shares, net of issuance costs Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options a 1 for 4.86 reverse share split of our common and preferred shares effected on October 1, 2014
2014-12-31
2014-12-15 1418.13 未披露 定期报告 2014-11-30
2014-11-05 1357.97 未披露
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the conversion of all outstanding preferred shares into an aggregate of 7,725,924 common shares upon the closing of this offering, including the conversion of all of our outstanding Series A preferred shares and Series B preferred shares into 2,146,353 common shares and the conversion of all of our outstanding Series E preferred shares into 5,579,571 common shares;a 1 for 4.86 reverse share split of our common and preferred shares effected on October 1, 2014
2014-11-05
2014-12-15 134.96 646.85
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From December 31, 2013 to October 2, 2014 Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options On October 1, 2014, the Company effected a 1 for 4.86 reverse share split of its common and Series A, B and E redeemable convertible preferred shares. All of the share numbers, share prices, and exercise prices in these financial statements have been adjusted, on a retroactive basis, to reflect this 1 for 4.86 reverse share split .
2014-10-02
2014-09-10 655.21 3143.73
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From December 31, 2013 to June 30, 2014 Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options
2014-06-30
1.Common Stock offered 10,526,317 shares by the company. 2.The underwriters exercised their option to purchase common stock 1,710,526 shares.
From December 31, 2024 to December 31, 2025 Issuance of common shares pursuant to equity incentive plans Issuance of common shares, net Exercise of warrant
From June 30, 2025 to September 30, 2025 Issuance of common shares pursuant to equity incentive plans
From March 31, 2025 to June 30, 2025 Issuance of common shares pursuant to equity incentive plans
From December 31, 2024 to March 31, 2025 Issuance of common shares pursuant to equity incentive plans
From December 31, 2023 to December 31, 2024 Exercise of stock options Issuance of common shares, net
From June 30, 2024 to September 30, 2024 Issued pursuant to exercise of stock options
From March 31, 2024 to June 30, 2024 Issued pursuant to exercise of stock options
From December 31, 2023 to March 31, 2024 Issued pursuant to exercise of stock options
From December 31, 2022 to December 31, 2023 Issuance of common shares and pre-funded warrants, net of issuance costs Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
Common shares offered 8,461,542 shares by the company
From June 30, 2023 to September 30, 2023 Issued pursuant to exercise of stock options Issuance of common shares, net of issuance costs Conversion of pre-funded warrants to common shares
From March 31, 2023 to June 30, 2023 Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
From December 31, 2022 to March 31, 2023 Conversion of pre-funded warrants to common shares Issued pursuant to exercise of stock options
From December 31, 2021 to December 31, 2022 Issued pursuant to exercise of stock options Issuance of common shares and pre-funded warrants, net of issuance costs Conversion of preferred shares to common shares
From June 30, 2022 to September 30, 2022 Issued pursuant to exercise of stock options
From March 31, 2022 to June 30, 2022 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
1.Common shares offered by 7,868,854 shares 2.The number of common shares to be outstanding after this offering is based on 53,059,049 common shares as of March 31, 2022
From December 31, 2021 to March 31, 2022 Conversion of preferred shares to common shares Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
From December 31, 2020 to December 31, 2021 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
1.Common shares offered 8,474,577 shares. 2.The number of common shares to be outstanding after this offering is based on 42,133,568 common shares outstanding as of June 30, 2021.
From June 30, 2021 to September 30, 2021 Issued pursuant to exercise of stock options
From March 31, 2021 to June 30, 2021 Issued pursuant to exercise of stock options
From December 31, 2020 to March 31, 2021 Issuance of common shares and pre-funded warrants, net of issuance costs Issued pursuant to exercise of stock options
1.Common shares offered by the company 4,324,325 shares. 2.The number of common shares to be outstanding after this offering is based on 36,028,125 common shares outstanding as of December 31, 2020, which number includes 1,016,000 common shares issuable upon the conversion of 1,016,000 of Series 1 Preferred Shares outstanding as of December 31, 2020.
From December 31, 2019 to December 31, 2020 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
from June 30, 2020 to September 30, 2020 Issued pursuant to exercise of stock options
from March 31, 2020 to June 30, 2020 Issued pursuant to exercise of stock options
from December 31, 2019 to March 31, 2020 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
1.Common shares offered by us 3,750,000 common shares 2.The number of common shares to be outstanding after this offering is based on 26,884,594 common shares outstanding as of September 30, 2019
from December 31, 2018 to December 31, 2019 Issuance of common shares,net of issuance costs Issued pursuant to exercise of stock options
from June 30, 2019 to September 30, 2019 Issued pursuant to exercise of stock options
from March 31, 2019 to June 30,2019 Issued pursuant to exercise of stock options
from December 31, 2018 to March 31, 2019 Issued pursuant to exercise of stock options
from December 31, 2017 to December 31, 2018 Issuance of common shares,net of issuance costs Issued (cancelled) pursuant to exchange agreement Conversion of preferred shares to common shares Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options and warrants
from December 31, 2017 to September 30, 2018 Issuance of common shares,net of issuance costs Issued (cancelled) pursuant to exchange agreement Conversion of preferred shares to common shares Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options and warrants
from December 31, 2017 to June 30, 2018 Issued (cancelled) pursuant to exchange agreement Issuance of common shares, net of issuance costs Cancelled pursuant to termination of collaboration agreement Issued pursuant to exercise of stock options
from December 31, 2017 to March 28, 2018 Issued (cancelled) pursuant to exchange agreement Cancelled pursuant to termination of collaboration agreement
from December 31, 2016 to June 30, 2017 Issued pursuant to exercise of stock options
from December 31, 2016 to March 31, 2017 Issued pursuant to exercise of stock options
from December 31, 2015 to December 31, 2016 Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
from December 31, 2015 to September 30, 2016 Issuance of common shares, net of issuance costs Issued pursuant to exercise of stock options
from December 31, 2015 to June 30, 2016 Issued pursuant to exercise of stock options
From December 31, 2015 to March 4, 2016 Issued pursuant to exercise of stock options
from December 31, 2014 to December 31, 2015 Issued pursuant to exercise of stock options
from December 31, 2014 to September 30, 2015 Issued pursuant to exercise of stock options
from December 31, 2014 to June 30, 2015 Issued pursuant to exercise of stock options
from December 31, 2014 to March 31, 2015 Issued pursuant to exercise of stock options
From December 31, 2013 to December 31, 2014 Conversion of Series A, B and E convertible preferred shares Issuance of common shares, net of issuance costs Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options a 1 for 4.86 reverse share split of our common and preferred shares effected on October 1, 2014
the conversion of all outstanding preferred shares into an aggregate of 7,725,924 common shares upon the closing of this offering, including the conversion of all of our outstanding Series A preferred shares and Series B preferred shares into 2,146,353 common shares and the conversion of all of our outstanding Series E preferred shares into 5,579,571 common shares;a 1 for 4.86 reverse share split of our common and preferred shares effected on October 1, 2014
From December 31, 2013 to October 2, 2014 Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options On October 1, 2014, the Company effected a 1 for 4.86 reverse share split of its common and Series A, B and E redeemable convertible preferred shares. All of the share numbers, share prices, and exercise prices in these financial statements have been adjusted, on a retroactive basis, to reflect this 1 for 4.86 reverse share split .
From December 31, 2013 to June 30, 2014 Issuance of common shares on conversion of subscription rights Issued pursuant to exercise of stock options