| | 问：请公司考虑下收购智飞生物（来自: 上证E互动） | | 答：尊敬的投资者您好，感谢您的关注。 |
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| | 问：请问gr1802的目前进度以及后面的预期，两个突破性药物gr1803和gr2001有没有BD的考虑（来自: 上证E互动） | | 答：尊敬的投资者您好，公司GR1802注射液的多个适应症均处于临床试验阶段，其中进度较快的中、重度特应性皮炎适应症和慢性鼻窦炎伴鼻息肉适应症正处于Ⅲ期临床试验阶段。公司将积极推动在研产品开发工作，根据进展情况履行信息披露义务。感谢您的关注。 |
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| | 问：你家募投项目第一个到期了，是延期还是完事了，你也没披露啊，不监管啊（来自: 上证E互动） | | 答：尊敬的投资者您好，公司一期改扩建项目新增20,000L的抗体药物原液产能并投入使用，有力保障公司上市品种的商业化生产。公司按照规划并结合实际推动募投项目建设，匹配公司发展需求。具体募投项目进展公司将在定期报告及专项报告中披露，感谢您的关注。 |
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| | 问：请问贵司的新药有纳入24年医保目录谈判吗？（来自: 上证E互动） | | 答：尊敬的投资者您好，公司赛立奇单抗注射液（金立希）于2024年8月获批上市，未赶上2024年国家医保谈判，感谢您的关注。 |
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| | 问：注意到公司的研发投入在2024年前三季度大幅增加，这是否意味着公司在进行哪些新药或技术研发?这些投资是否预示着未来会有重大产品发布或技术突破?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，2024年前三季度公司研发投入为437,938,634.20元，公司多项在研产品取得临床进展。感谢您的关注。 |
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| | 问：在当前的财务结构下，公司如何看待未来可能的利率风险?如果市场利率上升，对公司现有的债务负担会产生怎样的影响?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，公司通过定期分析负债结构和期限来评估其现有财务结构下的利率风险，以确保有充裕的资金。感谢您的关注。 |
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| | 问：在当前的市场环境下，智翔金泰如何保持其在生物制药领域的竞争力和创新能力?公司有没有在开发新的治疗领域或者疾病靶点，以驱动未来的增长?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，公司聚焦于自身免疫性疾病、感染性疾病和肿瘤三大治疗领域，专注于抗体药物研发及抗体药物技术平台的构建，建立了基于新型噬菌体呈现系统的单抗药物发现技术平台和双特异性抗体药物发现技术平台。公司基于前述技术平台开发的多款创新单克隆抗体药物和双特异性抗体药物已经进入临床研究阶段。公司紧跟全球药物靶点前沿动态，结合未被满足的临床需求，充分发挥自身技术优势，动态调整药物研发策略，确保研发管线与市场需求的匹配，推动企业创新引擎高效运转。感谢您的关注。 |
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| | 问：针对目前的在研项目，公司是否有考虑通过合作或者并购来加速产品研发和市场推广?如果有，能透露一些潜在的合作伙伴或者并购策略吗?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，公司积极推进在研产品的临床进展，公司将根据信息披露要求披露产品进展情况。感谢您的关注。 |
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| | 问：虽然净利润持续为负，但投资者看到公司在研发上的大手笔投入。请问这种亏损状态预计会持续多久?公司有什么具体的扭亏为盈策略吗?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好。创新药行业具有高投入、高风险、长周期的特点，公司首款产品赛立奇单抗注射液（金立希）中重度斑块状银屑病适应症于2024年8月获批上市，已实现主营业务收入。同时，公司将积极推动在研品种的研发进展，逐步实现在研品种的商业化。未来若在研品种陆续获批上市,公司的财务指标、经营业绩等有望持续改善。感谢您的关注! |
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| | 问：在创新药研发方面投入巨大，能否请您分享一下公司在研项目的管线中，除了已经提及的GR2001、GR1803、GR1802等产品，还有哪些潜力药品正在研发中?这些药品的市场前景和商业化计划是怎样的呢?（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，公司在研产品15个，均为自主研发，覆盖自身免疫性疾病、感染性疾病、肿瘤等治疗领域。公司9个产品获批开展临床试验，其中赛立奇单抗（GR1501）针对中重度斑块状银屑病适应症于2024年8月获批上市，中轴型脊柱关节炎适应症于2024年1月提交新药上市申请获受理；GR1801疑似狂犬病病毒暴露后的被动免疫适应症、GR1802中重度特应性皮炎、慢性鼻窦炎伴鼻息肉适应症和GR2001预防破伤风适应症已进入III期临床试验阶段；GR1802哮喘、慢性自发性荨麻疹和过敏性鼻炎适应症、GR1603系统性红斑狼疮适应症和GR1803多发性骨髓瘤适应症处于II期临床试验阶段。公司将积极推动在研品种的研发进展，逐步实现在研品种的商业化。感谢您的关注。 |
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| | 问：请问公司是否有布局或收购重组罕见遗传及血液领域、消化等方面管线，回购资金是否到位，现在各省市对于创新都大力支持为什么公司都没有体现出支持或补助奖励（来自: 上证E互动） | | 答：尊敬的投资者您好！公司聚焦自身免疫性疾病、感染性疾病和肿瘤三大治疗领域，持续开发单克隆抗体药物及双特异性抗体药物。2024年11月20日，公司披露了《关于首次回购股份的公告》，后续公司将根据回购股份事项进展情况及时履行信息披露义务。公司获政府补助情况详见已披露定期报告。感谢您的关注！ |
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| | 问：公司披露的募投项目抗体产业化一期项目显示2024年8月达到预定可使用状态,现在到期了没看到延期也没有结项请问项目实际执行情况是怎么样呐，是否延期，半年报投入还未达50（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好，公司一期改扩建项目新增20,000L的抗体药物原液产能并投入使用，有力保障公司上市品种的商业化生产。公司按照规划并结合实际推动募投项目建设，匹配公司发展需求。具体募投项目进展公司将在定期报告及专项报告中披露，感谢您的关注。 |
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| | 问：公司如何平衡好营业收入与高额的研发投入？对净利润的扭亏为盈有没有个时间表？（来自: 投资者关系互动平台） | | 答：尊敬的投资者您好。创新药行业具有高投入、高风险、长周期的特点，公司首款产品赛立奇单抗注射液（金立希）中重度斑块状银屑病适应症于2024年8月获批上市，已实现主营业务收入。同时，赛立奇单抗注射液中轴型脊柱关节炎适应症处于新药上市评审阶段，GR1801注射液、GR1802注射液和GR2001注射液的多个适应症处于III期临床试验阶段。未来前述品种若陆续获批上市,公司的财务指标、经营业绩等有望持续改善。感谢您的关注! |
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| | 问：请问公司为什么对董事长的回购提议已读不回，狗抗还有多久结束三期（来自: 上证E互动） | | 答：尊敬的投资者您好。经董事会审议通过，公司于2024年10月16日披露了《关于以集中竞价交易方式回购股份的方案》，具体回购事项正在有序开展。2023年9月，GR1801注射液完成了III期临床试验入组，目前处于III期临床试验阶段。公司将继续推动项目进展，争取早日为患者提供更多产品服务。感谢您的关注！ |
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