股本结构
单位：万股
| 公告日期 | 2025-11-13 | 2025-11-13 | 2025-08-06 | 2025-08-06 | 2025-05-14 | 2025-05-14 |
|---|---|---|---|---|---|---|
| 证券总股本 | 19232.40 | 19195.37 | 19169.87 | 19164.15 | 19152.71 | 19148.15 |
| 普通股本 | 19232.40 | 19195.37 | 19169.87 | 19164.15 | 19152.71 | 19148.15 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-11-11 | 2025-09-30 | 2025-08-04 | 2025-06-30 | 2025-05-12 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-11-13 | 19232.40 | 未披露 | 定期报告 | 2025-11-11 |
| 2025-11-13 | 19195.37 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
|
2025-09-30 |
| 2025-08-06 | 19169.87 | 未披露 | 定期报告 | 2025-08-04 |
| 2025-08-06 | 19164.15 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common shares pursuant to exercise of options
|
2025-06-30 |
| 2025-05-14 | 19152.71 | 未披露 | 定期报告 | 2025-05-12 |
| 2025-05-14 | 19148.15 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to exercise of options
Issuance of common shares upon vesting of RSUs
|
2025-03-31 |
| 2025-04-04 | 19148.02 | 未披露 | 定期报告 | 2025-03-24 |
| 2025-03-27 | 18996.35 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of stock options
Issuance of common shares upon settlement of RSUs
Issuance of common shares pursuant to exercise of ESPP
|
2024-12-31 |
| 2024-11-06 | 18949.17 | 未披露 | 定期报告 | 2024-11-04 |
| 2024-11-06 | 18943.81 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to exercise of options
|
2024-09-30 |
| 2024-08-08 | 18878.20 | 未披露 | 定期报告 | 2024-08-07 |
| 2024-08-08 | 18873.90 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
|
2024-06-30 |
| 2024-05-02 | 18871.74 | 未披露 | 定期报告 | 2024-04-30 |
| 2024-05-02 | 18019.22 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to ESPP
Issuance of common shares upon vesting of RSUs
|
2024-03-31 |
| 2024-04-10 | 18017.49 | 未披露 | 定期报告 | 2024-03-25 |
| 2024-03-05 | 17949.22 | 未披露 | 定期报告 | 2024-03-01 |
| 2024-03-05 | 16986.74 | 未披露 |
更多>>
From December 31,2022 to December 31,2023
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of ESPP
Issuance of common shares pursuant to exercise of stock options
|
2023-12-31 |
| 2023-11-07 | 16769.52 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to the Open Market Sale Agreement
|
2023-09-30 |
| 2023-08-03 | 16755.67 | 未披露 | 定期报告 | 2023-08-01 |
| 2023-08-03 | 16692.27 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common shares pursuant to the Open Market Sale Agreement
|
2023-06-30 |
| 2023-05-04 | 16613.36 | 未披露 | 定期报告 | 2023-05-02 |
| 2023-05-04 | 16513.22 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to ESPP
|
2023-03-31 |
| 2023-04-12 | 16507.34 | 未披露 | 定期报告 | 2023-03-27 |
| 2023-03-02 | 16257.10 | 未披露 | 定期报告 | 2023-02-28 |
| 2023-03-02 | 15745.54 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of stock options
Issuance of common shares pursuant to exercise of ESPP
Issuance of common shares pursuant to Share Purchase Agreement
|
2022-12-31 |
| 2022-11-09 | 15646.71 | 未披露 | 定期报告 | 2022-11-08 |
| 2022-11-09 | 15271.17 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to the Open Market Sale Agreement
|
2022-09-30 |
| 2022-08-04 | 14995.06 | 未披露 | 定期报告 | 2022-08-02 |
| 2022-08-04 | 14879.43 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common shares pursuant to exercise of options
|
2022-06-30 |
| 2022-05-05 | 14872.82 | 未披露 |
更多>>
From December 31, 2021 to March 28, 2022
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to Share Purchase Agreement
|
2022-03-28 |
| 2022-03-03 | 14864.17 | 未披露 | 定期报告 | 2022-03-03 |
| 2022-03-03 | 14498.77 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Conversion of Preferred Shares into Common Shares
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of ESPP options
Issuance of common shares pursuant to exercise of options
|
2021-12-31 |
| 2021-11-04 | 13526.92 | 未披露 | 定期报告 | 2021-11-02 |
| 2021-11-04 | 11026.49 | 116.40 | 定期报告 | 2021-09-30 |
| 2021-08-05 | 9916.12 | 未披露 | 定期报告 | 2021-08-03 |
| 2021-08-05 | 9770.00 | 116.40 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
|
2021-06-30 |
| 2021-05-05 | 9638.77 | 未披露 | 定期报告 | 2021-05-03 |
| 2021-04-08 | 9633.64 | 未披露 | 定期报告 | 2021-04-07 |
| 2021-05-05 | 9624.54 | 116.40 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
|
2021-03-31 |
| 2021-03-04 | 9558.39 | 未披露 | 定期报告 | 2021-03-03 |
| 2021-03-04 | 8967.87 | 116.40 |
更多>>
From December 31,2019 to December 31,2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
|
2020-12-31 |
| 2020-11-05 | 8490.93 | 未披露 | 定期报告 | 2020-11-05 |
| 2020-11-05 | 8461.86 | 116.40 |
更多>>
From June 30, 2020 to September 30, 2020
Accretion of accumulated dividends on Preferred Shares
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
|
2020-09-30 |
| 2020-08-28 | 8290.93 | 116.40 | 定期报告 | 2020-08-27 |
| 2020-08-07 | 8090.93 | 未披露 | 定期报告 | 2020-08-05 |
| 2020-08-07 | 7125.66 | 116.40 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
|
2020-06-30 |
| 2020-05-11 | 6896.14 | 116.40 |
更多>>
From December 31, 2019 to March 31, 2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
|
2020-03-31 |
| 2020-03-05 | 6894.14 | 未披露 | 定期报告 | 2020-03-02 |
| 2020-03-05 | 6478.03 | 116.40 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
|
2019-12-31 |
| 2019-12-23 | 6211.20 | 未披露 | 定期报告 | 2019-12-19 |
| 2019-08-05 | 5685.02 | 116.40 |
更多>>
from March 31, 2019 to June 30,2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
|
2019-06-30 |
| 2019-04-23 | 5685.02 | 未披露 | 定期报告 | 2019-04-17 |
| 2019-05-06 | 5625.58 | 116.40 |
更多>>
from December 31, 2018 to March 31, 2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
|
2019-03-31 |
| 2019-03-07 | 5612.09 | 未披露 | 定期报告 | 2019-03-05 |
| 2019-03-07 | 5551.88 | 116.40 |
更多>>
from December 31, 2017 to December 31, 2018
Issuance of Preferred Shares, net of issuance cost
Issuance of common shares pursuant to exercise of options
|
2018-12-31 |
| 2018-11-07 | 5547.72 | 未披露 | 定期报告 | 2018-10-31 |
| 2018-11-07 | 5547.23 | 116.40 |
更多>>
from June 30, 2018 to September 30, 2018
Issuance of common shares pursuant to exercise of options
|
2018-09-30 |
| 2018-08-03 | 5540.43 | 116.40 | 定期报告 | 2018-07-31 |
| 2018-08-03 | 5532.53 | 116.40 |
更多>>
From December 31, 2017 to June 30, 2018
Issuance of Preferred Shares, net of issuance cost of $135
Issuance of common shares pursuant to exercise of options
|
2018-06-30 |
| 2018-05-04 | 5516.80 | 116.40 | 定期报告 | 2018-04-30 |
| 2018-04-25 | 5514.45 | 未披露 | 定期报告 | 2018-04-18 |
| 2018-05-04 | 5508.72 | 116.40 |
更多>>
from December 31, 2017 to March 31, 2018
Issuance of Preferred Shares, net of issuance cost of $135
Issuance of common shares pursuant to exercise of options
|
2018-03-31 |
| 2018-03-16 | 5507.00 | 未披露 | 定期报告 | 2018-03-06 |
| 2018-03-16 | 5506.07 | 50.00 |
更多>>
from December 31, 2016 to December 31, 2017
Issuance of Preferred Shares, net of issuance cost of $1,131,000
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2017-12-31 |
| 2017-11-02 | 5505.20 | 未披露 | 定期报告 | 2017-10-31 |
| 2017-11-02 | 5505.20 | 未披露 |
更多>>
from December 31, 2016 to September 30, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2017-09-30 |
| 2017-08-03 | 5502.70 | 未披露 | 定期报告 | 2017-07-31 |
| 2017-08-03 | 5502.70 | 未披露 |
更多>>
from December 31, 2016 to June 30, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2017-06-30 |
| 2017-05-04 | 5502.46 | 未披露 | 定期报告 | 2017-04-30 |
| 2017-05-04 | 5502.45 | 未披露 |
更多>>
from December 31, 2016 to March 31, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2017-03-31 |
| 2017-03-22 | 5502.32 | 未披露 | 定期报告 | 2017-03-14 |
| 2017-03-22 | 5484.15 | 未披露 |
更多>>
From December 31, 2015 to December 31, 2016
Issuance of common shares:pursuant to exercise of options
Issuance of common shares:pursuant to exercise of warrants
|
2016-12-31 |
| 2016-12-23 | 5484.15 | 未披露 | 定期报告 | 2016-12-21 |
| 2016-11-03 | 5484.15 | 未披露 |
更多>>
from December 31, 2015 to September 30, 2016
Issuance of common shares:pursuant to exercise of options
Issuance of common shares:pursuant to exercise of warrants
|
2016-09-30 |
| 2016-08-04 | 5479.67 | 未披露 |
更多>>
from December 31, 2015 to June 30, 2016
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2016-06-30 |
| 2016-05-04 | 5462.57 | 未披露 | 定期报告 | 2016-04-30 |
| 2016-05-04 | 5462.57 | 未披露 |
更多>>
From December 31, 2015 to March 31, 2016
Issuance of common shares pursuant to exercise of options
|
2016-03-31 |
| 2016-03-09 | 5462.57 | 未披露 | 定期报告 | 2016-02-29 |
| 2016-03-09 | 5457.07 | 未披露 |
更多>>
from December 31, 2014 to December 31, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the public offering, net of issuance costs of $9,700,000
Increase of equity instruments in conjunction with the acquisition of Arbutus Inc.
|
2015-12-31 |
| 2015-11-05 | 5456.98 | 未披露 |
更多>>
from December 31, 2014 to September 30, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the public offering, net of issuance costs of $9,700,000
Issuance of equity instruments in conjunction with the acquisition of Arbutus Inc.
|
2015-09-30 |
| 2015-08-07 | 5432.84 | 未披露 | 定期报告 | 2015-07-31 |
| 2015-08-07 | 5430.34 | 未披露 |
更多>>
from December 31, 2014 to June 30, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $9,700,000
Issuance of equity instruments in conjunction with the acquisition of Arbutus Inc.
|
2015-06-30 |
| 2015-05-06 | 5422.43 | 未披露 | 定期报告 | 2015-04-30 |
| 2015-05-29 | 5420.63 | 未披露 | 定期报告 | 2015-04-23 |
| 2015-05-06 | 5409.59 | 未披露 |
更多>>
from December 31, 2014 to March 31, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $9,700,000
Issuance of common shares in conjunction with the acquisition of OnCore
|
2015-03-31 |
| 2015-03-13 | 4656.75 | 未披露 | 定期报告 | 2015-03-09 |
| 2015-02-04 | 2245.57 | 未披露 | 定期报告 | 2015-01-29 |
| 2015-03-13 | 2243.82 | 未披露 |
更多>>
from December 31, 2013 to December 31, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
|
2014-12-31 |
| 2014-12-10 | 2240.34 | 未披露 | 定期报告 | 2014-12-09 |
| 2014-11-26 | 2238.02 | 未披露 | 定期报告 | 2014-11-24 |
| 2014-11-07 | 2231.39 | 未披露 | 定期报告 | 2014-10-31 |
| 2014-11-07 | 2228.19 | 未披露 |
更多>>
from December 31, 2013 to September 30, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
|
2014-09-30 |
| 2014-08-14 | 2210.60 | 未披露 | 定期报告 | 2014-08-12 |
| 2014-08-14 | 2207.97 | 未披露 |
更多>>
from December 31, 2013 to June 30, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
|
2014-06-30 |
| 2014-05-14 | 2207.69 | 未披露 | 定期报告 | 2014-05-08 |
| 2014-05-14 | 2199.21 | 未披露 |
更多>>
from December 31,2013 to March 31, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
|
2014-03-31 |
| 2014-03-28 | 2194.58 | 未披露 | 定期报告 | 2014-03-21 |
| 2014-02-28 | 1968.01 | 未披露 | 定期报告 | 2014-02-27 |
| 2014-02-21 | 1956.20 | 未披露 | 定期报告 | 2014-02-20 |
| 2014-03-06 | 1904.89 | 未披露 |
更多>>
from December 31, 2012 to December 31, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $2,461,683
|
2013-12-31 |
| 2013-11-14 | 1902.11 | 未披露 | 定期报告 | 2013-11-01 |
| 2013-11-14 | 1455.42 | 未披露 |
更多>>
from December 31, 2012 to September 30, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2013-09-30 |
| 2013-08-12 | 1452.72 | 未披露 | 定期报告 | 2013-07-31 |
| 2013-08-12 | 1442.34 | 未披露 |
更多>>
From December 31, 2012 to June 30, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2013-06-30 |
| 2013-05-14 | 1438.82 | 未披露 | 定期报告 | 2013-04-30 |
| 2013-05-14 | 1437.67 | 未披露 |
更多>>
From December 31, 2012 to March 31, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
|
2013-03-31 |
| 2013-01-16 | 1431.94 | 未披露 | 定期报告 | 2013-01-15 |
| 2013-01-04 | 1430.38 | 未披露 | 定期报告 | 2013-01-03 |
| 2013-03-27 | 1430.54 | 未披露 |
更多>>
from December 31, 2011 to December 31, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
|
2012-12-31 |
| 2012-11-13 | 1400.79 | 未披露 |
更多>>
from December 31, 2011 to September 30, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
|
2012-09-30 |
| 2012-08-14 | 1400.79 | 未披露 | 定期报告 | 2012-07-31 |
| 2012-08-14 | 1399.97 | 未披露 |
更多>>
from December 31, 2011 to June 30, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
|
2012-06-30 |
| 2012-05-15 | 1399.95 | 未披露 |
更多>>
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
|
2012-03-31 |
| 2012-03-27 | 1214.86 | 未披露 |
更多>>
from December 31, 2010 to December 31, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
|
2011-12-31 |
| 2011-11-08 | 1214.85 | 未披露 |
更多>>
from December 31, 2010 to September 30, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
|
2011-09-30 |
| 2011-08-11 | 1213.18 | 未披露 |
更多>>
from December 31, 2010 to June 30, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
|
2011-06-30 |
| 2011-05-10 | 1034.19 | 未披露 |
更多>>
Issuance of common shares pursuant to exercise of options
|
2011-03-31 |
| 2011-03-31 | 1033.87 | 未披露 | 定期报告 | 2011-02-28 |
| 2011-06-03 | 1033.87 | 未披露 |
更多>>
from dec 31 2009 to dec 31 2010
Issuance of common shares pursuant to exercise of options
|
2010-12-31 |
| 2010-11-16 | 1033.74 | 未披露 |
更多>>
Issuance of common shares pursuant to exercise of options
|
2010-09-30 |
From June 30, 2025 to September 30, 2025
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
From March 31, 2025 to June 30, 2025
Issuance of common shares pursuant to exercise of options
From December 31, 2024 to March 31, 2025
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to exercise of options
Issuance of common shares upon vesting of RSUs
From December 31, 2023 to December 31, 2024
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of stock options
Issuance of common shares upon settlement of RSUs
Issuance of common shares pursuant to exercise of ESPP
From June 30, 2024 to September 30, 2024
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to exercise of options
From March 31, 2024 to June 30, 2024
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
From December 31, 2023 to March 31, 2024
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to ESPP
Issuance of common shares upon vesting of RSUs
From December 31,2022 to December 31,2023
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of ESPP
Issuance of common shares pursuant to exercise of stock options
From June 30, 2023 to September 30, 2023
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to the Open Market Sale Agreement
From March 31, 2023 to June 30, 2023
Issuance of common shares pursuant to the Open Market Sale Agreement
From December 31, 2022 to March 31, 2023
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to ESPP
From December 31, 2021 to December 31, 2022
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of stock options
Issuance of common shares pursuant to exercise of ESPP
Issuance of common shares pursuant to Share Purchase Agreement
From June 30, 2022 to September 30, 2022
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to the Open Market Sale Agreement
From March 31, 2022 to June 30, 2022
Issuance of common shares pursuant to exercise of options
From December 31, 2021 to March 28, 2022
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
Issuance of common shares pursuant to Share Purchase Agreement
From December 31, 2020 to December 31, 2021
Conversion of Preferred Shares into Common Shares
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of ESPP options
Issuance of common shares pursuant to exercise of options
From March 31, 2021 to June 30, 2021
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
From December 31, 2020 to March 31, 2021
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to ESPP
From December 31,2019 to December 31,2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
From June 30, 2020 to September 30, 2020
Accretion of accumulated dividends on Preferred Shares
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
From March 31, 2020 to June 30, 2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
From December 31, 2019 to March 31, 2020
Issuance of common shares pursuant to the Open Market Sales Agreement
Issuance of common shares pursuant to exercise of options
from December 31, 2018 to December 31, 2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
from March 31, 2019 to June 30,2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
from December 31, 2018 to March 31, 2019
Issuance of common shares pursuant to the Open Market Sale Agreement
Issuance of common shares pursuant to exercise of options
from December 31, 2017 to December 31, 2018
Issuance of Preferred Shares, net of issuance cost
Issuance of common shares pursuant to exercise of options
from June 30, 2018 to September 30, 2018
Issuance of common shares pursuant to exercise of options
From December 31, 2017 to June 30, 2018
Issuance of Preferred Shares, net of issuance cost of $135
Issuance of common shares pursuant to exercise of options
from December 31, 2017 to March 31, 2018
Issuance of Preferred Shares, net of issuance cost of $135
Issuance of common shares pursuant to exercise of options
from December 31, 2016 to December 31, 2017
Issuance of Preferred Shares, net of issuance cost of $1,131,000
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
from December 31, 2016 to September 30, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
from December 31, 2016 to June 30, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
from December 31, 2016 to March 31, 2017
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
From December 31, 2015 to December 31, 2016
Issuance of common shares:pursuant to exercise of options
Issuance of common shares:pursuant to exercise of warrants
from December 31, 2015 to September 30, 2016
Issuance of common shares:pursuant to exercise of options
Issuance of common shares:pursuant to exercise of warrants
from December 31, 2015 to June 30, 2016
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
From December 31, 2015 to March 31, 2016
Issuance of common shares pursuant to exercise of options
from December 31, 2014 to December 31, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the public offering, net of issuance costs of $9,700,000
Increase of equity instruments in conjunction with the acquisition of Arbutus Inc.
from December 31, 2014 to September 30, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the public offering, net of issuance costs of $9,700,000
Issuance of equity instruments in conjunction with the acquisition of Arbutus Inc.
from December 31, 2014 to June 30, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $9,700,000
Issuance of equity instruments in conjunction with the acquisition of Arbutus Inc.
from December 31, 2014 to March 31, 2015
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $9,700,000
Issuance of common shares in conjunction with the acquisition of OnCore
from December 31, 2013 to December 31, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
from December 31, 2013 to September 30, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
from December 31, 2013 to June 30, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
from December 31,2013 to March 31, 2014
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $4,085,000
from December 31, 2012 to December 31, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $2,461,683
from December 31, 2012 to September 30, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
From December 31, 2012 to June 30, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
From December 31, 2012 to March 31, 2013
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
from December 31, 2011 to December 31, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of warrants
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
from December 31, 2011 to September 30, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
from December 31, 2011 to June 30, 2012
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the private offering, net of issuance costs of $178,407 and net of initial fair value of warrants of $850,358
from December 31, 2010 to December 31, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
from December 31, 2010 to September 30, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
from December 31, 2010 to June 30, 2011
Issuance of common shares pursuant to exercise of options
Issuance of common shares in conjunction with the public offering, net of issuance costs of $475,568 and net of initial fair value of warrants of $742,809
Issuance of common shares pursuant to exercise of options
from dec 31 2009 to dec 31 2010
Issuance of common shares pursuant to exercise of options
Issuance of common shares pursuant to exercise of options