主要股东
注：以下部分股东代表特定权益共同体，直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | Entities affiliated with Fidelity Management & Research Company | 是 | 731.31万 | 12.71% | 新增 | 新增 | -- |
| 2 | Wellington Management Group, LLP | 是 | 682.56万 | 11.86% | 新增 | 新增 | -- |
| 3 | Entities affiliated with Celgene Corporation | 是 | 671.84万 | 11.68% | 新增 | 新增 | -- |
| 4 | Vanguard Specialized Funds - Vanguard Health Care Fund | 是 | 387.49万 | 6.73% | 新增 | 新增 | -- |
| 5 | Capital International Investors | 是 | 367.76万 | 6.39% | 新增 | 新增 | -- |
| 6 | 领航集团有限公司 | 是 | 330.21万 | 5.74% | 新增 | 新增 | -- |
内部人交易
| 日期 | 股东名称 | 变动股数(万股) | 交易后持股数量(万股) | 交易价格 | 是否直接持有 | 内部人类型 |
|---|---|---|---|---|---|---|
| 2025-11-12 | Scadden David |
|
1.78 | 18.09 | 是 | -- |
| 2025-11-12 | Scadden David |
|
1.76 | 43.84 | 是 | -- |
| 2025-11-11 | Gheuens Sarah |
|
6.42 | 25.01 | 是 | Chief Medical Officer |
| 2025-11-11 | Gheuens Sarah |
|
6.17 | 43.78 | 是 | Chief Medical Officer |
| 2025-10-30 | Gheuens Sarah |
|
6.19 | 25.01 | 是 | Chief Medical Officer |
| 2025-10-30 | Gheuens Sarah |
|
6.17 | 43.81 | 是 | Chief Medical Officer |
| 2025-10-27 | Gheuens Sarah |
|
6.50 | 25.01 | 是 | Chief Medical Officer |
| 2025-10-27 | Gheuens Sarah |
|
6.17 | 43.92 | 是 | Chief Medical Officer |
| 2025-10-08 | Scadden David |
|
1.78 | 18.09 | 是 | -- |
| 2025-10-08 | Scadden David |
|
1.76 | 41.00 | 是 | -- |
| 2025-09-30 | Scadden David |
|
1.78 | 18.09 | 是 | -- |
| 2025-09-30 | Scadden David |
|
1.76 | 40.00 | 是 | -- |
| 2025-09-26 | Jones Cecilia |
|
3.75 | 0.00 | 是 | Chief Financial Officer |
| 2025-09-26 | Jones Cecilia |
|
3.39 | 36.77 | 是 | Chief Financial Officer |
| 2025-09-05 | Washburn Theodore James Jr. |
|
0.09 | 36.87 | 是 | Principal Accounting Officer |
| 2025-08-27 | Scadden David |
|
1.78 | 18.09 | 是 | -- |
| 2025-08-27 | Scadden David |
|
1.76 | 40.00 | 是 | -- |
| 2025-08-11 | Ballal Rahul D. |
|
1.24 | 0.00 | 是 | -- |
| 2025-08-08 | Goff Brian |
|
13.46 | 0.00 | 是 | Chief Executive Officer |
| 2025-08-08 | Goff Brian |
|
12.35 | 36.67 | 是 | Chief Executive Officer |
| 2025-07-10 | Scadden David |
|
1.90 | 18.09 | 是 | -- |
| 2025-07-10 | Scadden David |
|
1.76 | 40.00 | 是 | -- |
| 2025-07-09 | Gheuens Sarah |
|
7.32 | 25.01 | 是 | Chief Medical Officer |
| 2025-07-09 | Gheuens Sarah |
|
6.21 | 37.93 | 是 | Chief Medical Officer |
| 2025-07-09 | Gheuens Sarah |
|
6.13 | 38.76 | 是 | Chief Medical Officer |
| 2025-07-01 | Gheuens Sarah |
|
6.54 | 0.00 | 是 | Chief Medical Officer |
| 2025-07-01 | Gheuens Sarah |
|
6.13 | 34.17 | 是 | Chief Medical Officer |
| 2025-06-24 | Goff Brian |
|
11.79 | 0.00 | 是 | Chief Executive Officer |
| 2025-06-24 | Goff Brian |
|
10.54 | 33.54 | 是 | Chief Executive Officer |
| 2025-06-24 | Goff Brian |
|
11.82 | 0.00 | 是 | Chief Executive Officer |
| 2025-06-24 | Goff Brian |
|
11.19 | 33.54 | 是 | Chief Executive Officer |
| 2025-06-24 | Milanova Tsveta |
|
2.89 | 0.00 | 是 | Chief Commercial Officer |
| 2025-06-24 | Milanova Tsveta |
|
2.61 | 33.54 | 是 | Chief Commercial Officer |
| 2025-06-24 | Jones Cecilia |
|
3.18 | 0.00 | 是 | Chief Financial Officer |
| 2025-06-24 | Jones Cecilia |
|
3.00 | 33.54 | 是 | Chief Financial Officer |
| 2025-06-24 | Gheuens Sarah |
|
5.99 | 0.00 | 是 | Chief Medical Officer |
| 2025-06-24 | Gheuens Sarah |
|
5.70 | 33.54 | 是 | Chief Medical Officer |
| 2025-06-24 | Burns James William |
|
3.14 | 0.00 | 是 | Chief Legal Officer |
| 2025-06-24 | Burns James William |
|
2.87 | 33.54 | 是 | Chief Legal Officer |
| 2025-06-18 | Smith Cynthia |
|
1.01 | 0.00 | 是 | -- |
| 2025-06-18 | Scadden David |
|
1.76 | 0.00 | 是 | -- |
| 2025-06-18 | Owen Adams Catherine |
|
0.61 | 0.00 | 是 | -- |
| 2025-06-18 | Ho Maykin |
|
1.70 | 0.00 | 是 | -- |
| 2025-06-18 | FOUSE JACQUALYN A |
|
15.13 | 0.00 | 是 | -- |
| 2025-06-18 | Foster-Cheek Kaye I |
|
0.75 | 0.00 | 是 | -- |
| 2025-06-18 | CAPELLO JEFFREY D |
|
0.61 | 0.00 | 是 | -- |
| 2025-06-18 | Ballal Rahul D. |
|
1.01 | 0.00 | 是 | -- |
| 2025-06-13 | Owen Adams Catherine |
|
0.40 | 0.00 | 是 | -- |
| 2025-06-13 | CAPELLO JEFFREY D |
|
0.40 | 0.00 | 是 | -- |
| 2025-04-08 | FOUSE JACQUALYN A |
|
15.67 | 0.00 | 是 | -- |
| 2025-04-08 | FOUSE JACQUALYN A |
|
14.92 | 25.90 | 是 | -- |
| 2025-03-01 | Jones Cecilia |
|
2.24 | 0.00 | 是 | Chief Financial Officer |
| 2025-03-01 | Jones Cecilia |
|
2.18 | 35.54 | 是 | Chief Financial Officer |
| 2025-03-01 | Jones Cecilia |
|
2.75 | 0.00 | 是 | Chief Financial Officer |
| 2025-03-01 | Jones Cecilia |
|
2.58 | 35.54 | 是 | Chief Financial Officer |
| 2025-03-01 | Milanova Tsveta |
|
2.29 | 35.54 | 是 | Chief Commercial Officer |
| 2025-03-01 | Milanova Tsveta |
|
2.46 | 0.00 | 是 | Chief Commercial Officer |
| 2025-03-01 | Gheuens Sarah |
|
4.82 | 0.00 | 是 | Chief Medical Officer |
| 2025-03-01 | Gheuens Sarah |
|
4.71 | 35.54 | 是 | Chief Medical Officer |
| 2025-03-01 | Gheuens Sarah |
|
5.11 | 0.00 | 是 | Chief Medical Officer |
| 2025-03-01 | Gheuens Sarah |
|
4.99 | 35.54 | 是 | Chief Medical Officer |
| 2025-03-01 | Gheuens Sarah |
|
5.56 | 0.00 | 是 | Chief Medical Officer |
| 2025-03-01 | Gheuens Sarah |
|
5.39 | 35.54 | 是 | Chief Medical Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
0.63 | 0.00 | 是 | Principal Accounting Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
0.60 | 35.54 | 是 | Principal Accounting Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
0.84 | 0.00 | 是 | Principal Accounting Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
0.77 | 35.54 | 是 | Principal Accounting Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
1.01 | 0.00 | 是 | Principal Accounting Officer |
| 2025-03-01 | Washburn Theodore James Jr. |
|
0.94 | 35.54 | 是 | Principal Accounting Officer |
| 2025-03-01 | Burns James William |
|
1.98 | 0.00 | 是 | Chief Legal Officer |
| 2025-03-01 | Burns James William |
|
1.87 | 35.54 | 是 | Chief Legal Officer |
| 2025-03-01 | Burns James William |
|
2.27 | 0.00 | 是 | Chief Legal Officer |
| 2025-03-01 | Burns James William |
|
2.15 | 35.54 | 是 | Chief Legal Officer |
| 2025-03-01 | Burns James William |
|
2.71 | 0.00 | 是 | Chief Legal Officer |
| 2025-03-01 | Burns James William |
|
2.54 | 35.54 | 是 | Chief Legal Officer |
| 2025-03-01 | Goff Brian |
|
8.73 | 0.00 | 是 | Chief Executive Officer |
| 2025-03-01 | Goff Brian |
|
8.31 | 35.54 | 是 | Chief Executive Officer |
| 2025-03-01 | Goff Brian |
|
10.11 | 0.00 | 是 | Chief Executive Officer |
| 2025-03-01 | Goff Brian |
|
9.23 | 35.54 | 是 | Chief Executive Officer |
| 2025-02-01 | Washburn Theodore James Jr. |
|
0.77 | 0.00 | 是 | Principal Accounting Officer |
| 2025-02-01 | Washburn Theodore James Jr. |
|
0.54 | 34.39 | 是 | Principal Accounting Officer |
| 2025-01-03 | Milanova Tsveta |
|
2.17 | 0.00 | 是 | Chief Commercial Officer |
| 2025-01-03 | Milanova Tsveta |
|
1.89 | 32.18 | 是 | Chief Commercial Officer |
| 2024-12-11 | Scadden David |
|
1.57 | 18.09 | 是 | -- |
| 2024-12-11 | Scadden David |
|
1.55 | 46.28 | 是 | -- |
| 2024-11-08 | Washburn Theodore James Jr. |
|
0.08 | 56.09 | 是 | Principal Accounting Officer |
| 2024-11-07 | Burns James William |
|
2.40 | 52.00 | 是 | Chief Legal Officer |
| 2024-11-07 | Burns James William |
|
1.57 | 52.56 | 是 | Chief Legal Officer |
| 2024-11-07 | Ballal Rahul D. |
|
1.80 | 25.99 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
0.99 | 53.32 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
0.80 | 54.41 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
1.80 | 25.99 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
1.44 | 57.24 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
0.95 | 58.57 | 是 | -- |
| 2024-11-07 | Ballal Rahul D. |
|
0.80 | 59.21 | 是 | -- |
| 2024-09-26 | Jones Cecilia |
|
2.27 | 0.00 | 是 | Chief Financial Officer |
| 2024-09-26 | Jones Cecilia |
|
2.02 | 49.03 | 是 | Chief Financial Officer |
| 2024-08-11 | Smith Cynthia |
|
0.80 | 0.00 | 是 | -- |
| 2024-08-11 | Ballal Rahul D. |
|
0.80 | 0.00 | 是 | -- |
| 2024-08-08 | Goff Brian |
|
8.99 | 0.00 | 是 | Chief Executive Officer |
| 2024-08-08 | Goff Brian |
|
7.88 | 42.75 | 是 | Chief Executive Officer |
| 2024-07-01 | Gheuens Sarah |
|
4.74 | 0.00 | 是 | Chief Medical Officer |
| 2024-07-01 | Gheuens Sarah |
|
4.37 | 43.85 | 是 | Chief Medical Officer |
| 2024-06-13 | Smith Cynthia |
|
0.57 | 0.00 | 是 | -- |
| 2024-06-13 | Ho Maykin |
|
1.49 | 0.00 | 是 | -- |
| 2024-06-13 | Scadden David |
|
1.55 | 0.00 | 是 | -- |
| 2024-06-13 | Owen Catherine E. |
|
0.20 | 0.00 | 是 | -- |
| 2024-06-13 | CAPELLO JEFFREY D |
|
0.20 | 0.00 | 是 | -- |
| 2024-06-13 | FOUSE JACQUALYN A |
|
14.08 | 0.00 | 是 | -- |
| 2024-06-13 | Foster-Cheek Kaye I |
|
0.89 | 0.00 | 是 | -- |
| 2024-06-13 | Foster-Cheek Kaye I |
|
0.53 | 0.00 | 是 | -- |
| 2024-06-13 | Schenkein David P |
|
12.62 | 0.00 | 是 | -- |
| 2024-06-13 | Ballal Rahul D. |
|
0.57 | 0.00 | 是 | -- |
| 2024-06-05 | Goff Brian |
|
7.93 | 0.00 | 是 | Chief Executive Officer |
| 2024-06-05 | Goff Brian |
|
6.72 | 48.84 | 是 | Chief Executive Officer |
| 2024-06-03 | Washburn Theodore James Jr. |
|
0.15 | 44.39 | 是 | Principal Accounting Officer |
| 2024-04-08 | FOUSE JACQUALYN A |
|
14.52 | 0.00 | 是 | -- |
| 2024-04-08 | FOUSE JACQUALYN A |
|
13.74 | 27.55 | 是 | -- |
| 2024-03-07 | Foster-Cheek Kaye I |
|
0.55 | 31.62 | 是 | -- |
| 2024-03-05 | Washburn Theodore James Jr. |
|
0.29 | 31.75 | 是 | Principal Accounting Officer |
| 2024-03-05 | Foster-Cheek Kaye I |
|
1.12 | 32.21 | 是 | -- |
| 2024-03-05 | Foster-Cheek Kaye I |
|
0.68 | 31.99 | 是 | -- |
| 2024-03-01 | Washburn Theodore James Jr. |
|
0.37 | 0.00 | 是 | Principal Accounting Officer |
| 2024-03-01 | Washburn Theodore James Jr. |
|
0.34 | 32.57 | 是 | Principal Accounting Officer |
| 2024-03-01 | Washburn Theodore James Jr. |
|
0.57 | 0.00 | 是 | Principal Accounting Officer |
| 2024-03-01 | Washburn Theodore James Jr. |
|
0.48 | 32.57 | 是 | Principal Accounting Officer |
| 2024-03-01 | Goff Brian |
|
5.79 | 0.00 | 是 | Chief Executive Officer |
| 2024-03-01 | Goff Brian |
|
5.38 | 32.57 | 是 | Chief Executive Officer |
| 2024-03-01 | Jones Cecilia |
|
1.55 | 0.00 | 是 | Chief Financial Officer |
| 2024-03-01 | Burns James William |
|
3.58 | 0.00 | 是 | Chief Legal Officer |
| 2024-03-01 | Burns James William |
|
3.45 | 32.57 | 是 | Chief Legal Officer |
| 2024-03-01 | Burns James William |
|
3.85 | 0.00 | 是 | Chief Legal Officer |
| 2024-03-01 | Burns James William |
|
3.72 | 32.57 | 是 | Chief Legal Officer |
| 2024-03-01 | Jones Cecilia |
|
1.48 | 32.57 | 是 | Chief Financial Officer |
| 2024-03-01 | Gheuens Sarah |
|
3.77 | 0.00 | 是 | Chief Medical Officer |
| 2024-03-01 | Gheuens Sarah |
|
3.64 | 32.57 | 是 | Chief Medical Officer |
| 2024-03-01 | Gheuens Sarah |
|
4.04 | 0.00 | 是 | Chief Medical Officer |
| 2024-03-01 | Gheuens Sarah |
|
3.91 | 32.57 | 是 | Chief Medical Officer |
| 2024-02-27 | Schenkein David P |
|
13.47 | 31.64 | 是 | -- |
| 2024-02-27 | Schenkein David P |
|
12.29 | 33.60 | 是 | -- |
| 2024-02-27 | Schenkein David P |
|
18.03 | 31.64 | 是 | -- |
| 2024-02-27 | Schenkein David P |
|
12.29 | 34.89 | 是 | -- |
| 2024-02-23 | Schenkein David P |
|
14.33 | 31.64 | 是 | -- |
| 2024-02-23 | Schenkein David P |
|
12.29 | 33.19 | 是 | -- |
| 2024-02-23 | Schenkein David P |
|
17.06 | 31.64 | 是 | -- |
| 2024-02-23 | Schenkein David P |
|
12.29 | 33.05 | 是 | -- |
| 2024-02-20 | Washburn Theodore James Jr. |
|
0.27 | 26.63 | 是 | Principal Accounting Officer |
| 2024-02-12 | Burns James William |
|
3.17 | 25.14 | 是 | Chief Legal Officer |
| 2024-02-12 | Burns James William |
|
3.22 | 0.00 | 是 | Chief Legal Officer |
| 2024-02-12 | Washburn Theodore James Jr. |
|
0.35 | 0.00 | 是 | Principal Accounting Officer |
| 2024-02-12 | Washburn Theodore James Jr. |
|
0.32 | 25.14 | 是 | Principal Accounting Officer |
| 2024-02-12 | Gheuens Sarah |
|
3.41 | 0.00 | 是 | Chief Medical Officer |
| 2024-02-12 | Gheuens Sarah |
|
3.34 | 25.14 | 是 | Chief Medical Officer |
| 2024-01-20 | Milanova Tsveta |
|
1.49 | 0.00 | 是 | Chief Commercial Officer |
| 2024-01-20 | Milanova Tsveta |
|
1.32 | 21.64 | 是 | Chief Commercial Officer |
| 2024-01-20 | Goff Brian |
|
5.71 | 0.00 | 是 | Chief Executive Officer |
| 2024-01-20 | Goff Brian |
|
4.94 | 21.64 | 是 | Chief Executive Officer |
| 2024-01-20 | Gheuens Sarah |
|
3.19 | 21.64 | 是 | Chief Medical Officer |
| 2024-01-20 | Gheuens Sarah |
|
3.36 | 0.00 | 是 | Chief Medical Officer |
| 2024-01-20 | FOUSE JACQUALYN A |
|
14.00 | 0.00 | 是 | -- |
| 2024-01-20 | FOUSE JACQUALYN A |
|
12.93 | 21.64 | 是 | -- |
| 2024-01-20 | Jones Cecilia |
|
1.50 | 0.00 | 是 | Chief Financial Officer |
| 2024-01-20 | Jones Cecilia |
|
1.31 | 21.64 | 是 | Chief Financial Officer |
| 2024-01-20 | Burns James William |
|
3.21 | 0.00 | 是 | Chief Legal Officer |
| 2024-01-20 | Burns James William |
|
3.04 | 21.64 | 是 | Chief Legal Officer |
| 2024-01-05 | Goff Brian |
|
5.21 | 0.00 | 是 | Chief Executive Officer |
| 2024-01-05 | Goff Brian |
|
4.01 | 22.99 | 是 | Chief Executive Officer |
| 2024-01-05 | FOUSE JACQUALYN A |
|
12.45 | 0.00 | 是 | -- |
| 2024-01-05 | FOUSE JACQUALYN A |
|
11.61 | 22.99 | 是 | -- |
| 2024-01-05 | Burns James William |
|
2.75 | 0.00 | 是 | Chief Legal Officer |
| 2024-01-05 | Burns James William |
|
2.63 | 22.99 | 是 | Chief Legal Officer |
| 2024-01-05 | Gheuens Sarah |
|
2.97 | 0.00 | 是 | Chief Medical Officer |
| 2024-01-05 | Gheuens Sarah |
|
2.79 | 22.99 | 是 | Chief Medical Officer |
| 2024-01-03 | Milanova Tsveta |
|
1.23 | 0.00 | 是 | Chief Commercial Officer |
| 2024-01-03 | Milanova Tsveta |
|
0.94 | 22.32 | 是 | Chief Commercial Officer |