股本结构
单位：万股
| 公告日期 | 2025-10-30 | 2025-10-30 | 2025-07-31 | 2025-07-31 | 2025-04-23 | 2025-04-23 |
|---|---|---|---|---|---|---|
| 证券总股本 | 12652.52 | 12650.00 | 12628.99 | 12618.70 | 12568.23 | 12565.94 |
| 普通股本 | 12652.52 | 12650.00 | 12628.99 | 12618.70 | 12568.23 | 12565.94 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-10-23 | 2025-09-30 | 2025-07-24 | 2025-06-30 | 2025-04-07 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-10-30 | 12652.52 | 未披露 | 定期报告 | 2025-10-23 |
| 2025-10-30 | 12650.00 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2025-09-30 |
| 2025-07-31 | 12628.99 | 未披露 | 定期报告 | 2025-07-24 |
| 2025-07-31 | 12618.70 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock under employee stock purchase plan
|
2025-06-30 |
| 2025-04-23 | 12568.23 | 未披露 | 定期报告 | 2025-04-07 |
| 2025-04-23 | 12565.94 | 未披露 | 定期报告 | 2025-03-31 |
| 2025-02-28 | 12551.58 | 未披露 | 定期报告 | 2025-02-19 |
| 2025-02-28 | 12449.50 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Exercise of pre-funded warrants
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2024-12-31 |
| 2024-11-05 | 12439.30 | 未披露 | 定期报告 | 2024-10-29 |
| 2024-11-05 | 12206.90 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2024-09-30 |
| 2024-08-01 | 12176.63 | 未披露 | 定期报告 | 2024-07-25 |
| 2024-08-01 | 12168.70 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock to employee stock purchase plan
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock upon exercise of stock options
|
2024-06-30 |
| 2024-05-07 | 12136.56 | 未披露 | 定期报告 | 2024-05-01 |
| 2024-04-26 | 12129.38 | 未披露 | 定期报告 | 2024-04-08 |
| 2024-05-07 | 12126.40 | 未披露 |
更多>>
From January 1, 2024 to March 31, 2024
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2024-03-31 |
| 2024-02-27 | 12058.17 | 未披露 | 定期报告 | 2024-02-20 |
| 2024-02-27 | 11955.60 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock upon exercise of stock options
Issuance of common stock and pre-funded warrants in common stock offering
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2023-12-31 |
| 2023-11-01 | 11849.99 | 未披露 | 定期报告 | 2023-10-24 |
| 2023-11-01 | 11835.90 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2023-09-30 |
| 2023-07-31 | 11773.73 | 未披露 | 定期报告 | 2023-07-24 |
| 2023-07-31 | 11757.90 | 未披露 | 定期报告 | 2023-06-30 |
| 2023-05-04 | 11645.70 | 未披露 | 定期报告 | 2023-05-01 |
| 2023-04-21 | 11617.91 | 未披露 | 定期报告 | 2023-04-03 |
| 2023-05-04 | 11617.90 | 未披露 |
更多>>
From January 1, 2023 to March 31, 2023
Issuance of common stock and pre-funded warrants in common stock offering
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock upon exercise of stock options
|
2023-03-31 |
| 2023-02-24 | 11446.53 | 未披露 |
更多>>
Common stock offered 3,174,603 shares by the company
|
2023-02-27 |
| 2023-02-21 | 11129.07 | 未披露 | 定期报告 | 2023-02-15 |
| 2023-02-21 | 11077.20 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock in follow-on offering, net of offering costs
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2022-12-31 |
| 2022-11-07 | 11057.55 | 未披露 | 定期报告 | 2022-11-01 |
| 2022-11-07 | 11047.60 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2022-09-30 |
| 2022-08-08 | 10986.53 | 未披露 | 定期报告 | 2022-08-04 |
| 2022-08-08 | 10684.10 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2022-06-30 |
| 2022-05-04 | 10652.18 | 未披露 | 定期报告 | 2022-04-29 |
| 2022-04-20 | 10647.37 | 未披露 | 定期报告 | 2022-04-05 |
| 2022-05-04 | 10643.99 | 未披露 |
更多>>
From January 1, 2022 to March 31, 2022
Common Stock -follow-on-offering
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2022-03-31 |
| 2022-03-28 | 10497.09 | 未披露 |
更多>>
1.Common stock offered 7,446,809 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 97,524,102 shares of common stock outstanding as of December 31, 2021.
|
2022-03-28 |
| 2022-02-28 | 9773.14 | 未披露 | 定期报告 | 2022-02-23 |
| 2022-02-28 | 9752.40 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
Issuance of shares in exchange of 2019 and 2020 Convertible Notes, including issuance cost
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2021-12-31 |
| 2021-11-18 | 9596.90 | 未披露 |
更多>>
1.Common stock offered 8,750,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 87,219,000 shares of common stock outstanding as of September 30, 2021.
|
2021-11-18 |
| 2021-11-08 | 8729.54 | 未披露 | 定期报告 | 2021-11-02 |
| 2021-11-08 | 8721.90 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2021-09-30 |
| 2021-08-09 | 8700.33 | 未披露 | 定期报告 | 2021-08-03 |
| 2021-08-09 | 8095.60 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
|
2021-06-30 |
| 2021-04-28 | 8049.68 | 未披露 | 定期报告 | 2021-04-23 |
| 2021-04-22 | 8044.00 | 未披露 | 定期报告 | 2021-04-05 |
| 2021-04-28 | 8043.80 | 未披露 |
更多>>
From January 1, 2021 To March 31, 2021
Issuance of shares in exchange of 2019 Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
|
2021-03-31 |
| 2021-02-25 | 8037.54 | 未披露 | 定期报告 | 2021-02-22 |
| 2021-02-25 | 7613.00 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Issuance of common stock in follow-on offering, net of offering costs
Recognition of equity component of convertible notes
Issuance of common stock to employee stock purchase plan
Issuance of common stock upon exercise of stock options
|
2020-12-31 |
| 2020-11-02 | 7573.69 | 未披露 | 定期报告 | 2020-10-28 |
| 2020-11-02 | 7570.00 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
|
2020-09-30 |
| 2020-07-30 | 7560.40 | 未披露 | 定期报告 | 2020-07-27 |
| 2020-07-30 | 7560.00 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock to employee stock purchase plan
|
2020-06-30 |
| 2020-04-29 | 7551.31 | 未披露 | 定期报告 | 2020-04-24 |
| 2020-04-22 | 7549.93 | 未披露 | 定期报告 | 2020-04-13 |
| 2020-04-29 | 7542.16 | 未披露 |
更多>>
From January 1, 2020 to March 31, 2020
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
|
2020-03-31 |
| 2020-02-27 | 7532.15 | 未披露 | 定期报告 | 2020-02-21 |
| 2020-01-13 | 7343.80 | 未披露 |
更多>>
1.Common stock offered 9,500,000 shares.
2.The number of shares of our common stock to be outstanding after this offering is based on 63,938,003 shares of our common stock outstanding as of December 31, 2019
|
2020-01-13 |
| 2020-02-27 | 6393.80 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common stock in follow-on offering,net of offering costs
Issuance of common stock upon exercise of stock options or warrants
|
2019-12-31 |
| 2019-11-05 | 6388.82 | 未披露 | 定期报告 | 2019-11-01 |
| 2019-11-05 | 6387.28 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock upon exercise of stock options
|
2019-09-30 |
| 2019-07-31 | 6369.55 | 未披露 | 定期报告 | 2019-07-24 |
| 2019-07-31 | 6367.24 | 未披露 |
更多>>
from March 31, 2019 to June 30, 2019
Issuance of common stock in follow-on offering, net of offering costs
|
2019-06-30 |
| 2019-04-30 | 6323.25 | 未披露 | 定期报告 | 2019-04-23 |
| 2019-05-07 | 6321.85 | 未披露 |
更多>>
from January 1, 2019 to March 31, 2019
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
|
2019-03-31 |
| 2019-03-07 | 5628.93 | 未披露 | 定期报告 | 2019-02-28 |
| 2019-02-26 | 5627.93 | 未披露 |
更多>>
from December 31, 2017 to December 31, 2018
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
|
2018-12-31 |
| 2018-11-13 | 5624.26 | 未披露 |
更多>>
from January 1, 2018 to September 30, 2018
Issuance of common stock upon exercise of stock options
Issuance of common stock in follow-on offering, net of offering costs
|
2018-09-30 |
| 2018-07-31 | 5617.81 | 未披露 | 定期报告 | 2018-07-20 |
| 2018-07-31 | 5615.44 | 未披露 |
更多>>
from January 1, 2018 to June 30, 2018
Issuance of common stock upon exercise of stock options
Issuance of common stock in follow-on offering, net of offering costs
|
2018-06-30 |
| 2018-04-30 | 5594.19 | 未披露 | 定期报告 | 2018-04-24 |
| 2018-04-25 | 5043.34 | 未披露 | 定期报告 | 2018-04-10 |
| 2018-04-30 | 5042.90 | 未披露 |
更多>>
from January 1, 2018 to March 31, 2018
Issuance of common stock upon exercise of stock options
|
2018-03-31 |
| 2018-03-19 | 5037.28 | 未披露 | 定期报告 | 2018-03-12 |
| 2018-03-19 | 5033.42 | 未披露 |
更多>>
from December 31, 2016 to December 31, 2017
Issuance of Series E convertible preferred stock, net of issuance costs
Conversion of convertible preferred stock to common stock
Issuance of common stock upon exercise of stock options
Issuance of common stock upon exercise of warrants
Issuance of common stock in initial public offering, net of issuance costs
|
2017-12-31 |
| 2017-12-20 | 5033.42 | 未披露 | 定期报告 | 2017-12-20 |
| 2017-11-09 | 4925.69 | 未披露 |
更多>>
1.Common stock offered 10,714,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 8,472,903 shares of our common stock outstanding as of September 30, 2017
3.a one-for-2.133 reverse stock split of our common stock that was effected on October 27, 2017
|
2017-11-09 |
| 2017-12-20 | 847.29 | 6413.95 |
更多>>
From January 1, 2017 To September 30, 2017
Issuance of Series E preferred stock, net of issuance costs
Exercise of stock options
|
2017-09-30 |
| 2015-11-02 | 1797.78 | 3524.81 |
更多>>
from January 1, 2015 to September 30, 2015
Issuance of common stock upon stock option exercise
Issuance of common stock upon closing Potentia asset purchase, net
|
2015-09-30 |
| 2015-10-15 | 977.78 | 3524.81 | 定期报告 | 2015-06-30 |
From June 30, 2025 to September 30, 2025
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From March 31, 2025 to June 30, 2025
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock under employee stock purchase plan
From December 31, 2023 to December 31, 2024
Exercise of pre-funded warrants
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
From June 30, 2024 to September 30, 2024
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From March 31, 2024 to June 30, 2024
Issuance of common stock to employee stock purchase plan
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock upon exercise of stock options
From January 1, 2024 to March 31, 2024
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From December 31, 2022 to December 31, 2023
Issuance of common stock upon exercise of stock options
Issuance of common stock and pre-funded warrants in common stock offering
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
From June 30, 2023 to September 30, 2023
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From January 1, 2023 to March 31, 2023
Issuance of common stock and pre-funded warrants in common stock offering
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock upon exercise of stock options
Common stock offered 3,174,603 shares by the company
From December 31, 2021 to December 31, 2022
Issuance of common stock in follow-on offering, net of offering costs
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
From June 30, 2022 to September 30, 2022
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From March 31, 2022 to June 30, 2022
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
From January 1, 2022 to March 31, 2022
Common Stock -follow-on-offering
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
1.Common stock offered 7,446,809 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 97,524,102 shares of common stock outstanding as of December 31, 2021.
From December 31, 2020 to December 31, 2021
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
Issuance of shares in exchange of 2019 and 2020 Convertible Notes, including issuance cost
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
1.Common stock offered 8,750,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 87,219,000 shares of common stock outstanding as of September 30, 2021.
From June 30, 2021 to September 30, 2021
Issuance of shares in exchange of Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
Issuance of common stock to employee stock purchase plan
From January 1, 2021 To March 31, 2021
Issuance of shares in exchange of 2019 Convertible Notes, including issuance costs
Issuance of common stock upon exercise of stock options
Vesting of restricted stock units, net of shares withheld for taxes
From December 31,2019 to December 31,2020
Issuance of common stock in follow-on offering, net of offering costs
Recognition of equity component of convertible notes
Issuance of common stock to employee stock purchase plan
Issuance of common stock upon exercise of stock options
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock to employee stock purchase plan
From January 1, 2020 to March 31, 2020
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
1.Common stock offered 9,500,000 shares.
2.The number of shares of our common stock to be outstanding after this offering is based on 63,938,003 shares of our common stock outstanding as of December 31, 2019
from December 31, 2018 to December 31, 2019
Issuance of common stock in follow-on offering,net of offering costs
Issuance of common stock upon exercise of stock options or warrants
from June 30, 2019 to September 30, 2019
Issuance of common stock upon exercise of stock options
from March 31, 2019 to June 30, 2019
Issuance of common stock in follow-on offering, net of offering costs
from January 1, 2019 to March 31, 2019
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
from December 31, 2017 to December 31, 2018
Issuance of common stock in follow-on offering, net of offering costs
Issuance of common stock upon exercise of stock options
from January 1, 2018 to September 30, 2018
Issuance of common stock upon exercise of stock options
Issuance of common stock in follow-on offering, net of offering costs
from January 1, 2018 to June 30, 2018
Issuance of common stock upon exercise of stock options
Issuance of common stock in follow-on offering, net of offering costs
from January 1, 2018 to March 31, 2018
Issuance of common stock upon exercise of stock options
from December 31, 2016 to December 31, 2017
Issuance of Series E convertible preferred stock, net of issuance costs
Conversion of convertible preferred stock to common stock
Issuance of common stock upon exercise of stock options
Issuance of common stock upon exercise of warrants
Issuance of common stock in initial public offering, net of issuance costs
1.Common stock offered 10,714,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 8,472,903 shares of our common stock outstanding as of September 30, 2017
3.a one-for-2.133 reverse stock split of our common stock that was effected on October 27, 2017
From January 1, 2017 To September 30, 2017
Issuance of Series E preferred stock, net of issuance costs
Exercise of stock options
from January 1, 2015 to September 30, 2015
Issuance of common stock upon stock option exercise
Issuance of common stock upon closing Potentia asset purchase, net