主要股东
注：以下部分股东代表特定权益共同体，直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | Entities affiliated with Baker Brothers Life Sciences L.P. | 是 | 946.70万 | 35.34% | 新增 | 新增 | -- |
| 2 | Hadley Harbor Master Investors (Cayman) II L.P. | 是 | 193.43万 | 7.22% | 新增 | 新增 | -- |
| 3 | Bill & Melinda Gates Foundation | 是 | 139.66万 | 5.21% | 新增 | 新增 | -- |
| 4 | Boxer Capital, LLC | 是 | 107.30万 | 4.01% | 新增 | 新增 | -- |
机构持股汇总
| 主力进出\报告期 | 2024-03-18 | 2024-03-05 | 2024-02-14 | 2024-02-13 | 2024-02-12 | 2024-02-09 |
|---|---|---|---|---|---|---|
| 机构数量(家) | 54 | 54 | 54 | 57 | 57 | 58 |
| 累计持有数量(万股) | 935.74 | 935.74 | 934.61 | 1158.86 | 1216.95 | 1253.28 |
| 累计市值(亿) | 0.02 | 0.02 | 0.03 | 0.03 | 0.03 | 0.03 |
| 持仓比例(%) | 24.62% | 28.36% | 28.32% | 35.12% | 36.88% | 37.98% |
| 净交易量(万股) |
注：若当期数据无主力机构持仓或公司定期报告未披露完毕，则不显示。
非主要股东机构持股变动
| 机构或基金名称 | 持有数量 | 持股市值(亿美元) | 持股变动(万股) | 变动比例(%) |
|---|---|---|---|---|
|
Acadian Asset Management Llc
|
4.41万股 | 0.0054 | - | 不足0.01 |
|
Aisling Capital Management Lp
|
38.77万股 | 0.05 | - | 不足0.01 |
|
Baker Bros. ADVISORS LP
|
217.75万股 | 0.27 | -135.53 | -38.36 |
|
Barclays Plc
|
4.75万股 | 0.0058 | - | 不足0.01 |
|
Bill & Melinda Gates Foundation
|
91.26万股 | 0.11 | - | 不足0.01 |
|
Blackrock Inc.
|
63.80万股 | 0.08 | -54.77 | -46.19 |
|
Boxer Capital, Llc
|
220.23万股 | 0.27 | - | 不足0.01 |
|
Bridgeway Capital Management, Llc
|
7.50万股 | 0.0092 | -7.50 | -50.00 |
|
Ensign Peak Advisors, Inc
|
10.53万股 | 0.01 | - | 不足0.01 |
|
Fmr Llc
|
3.33万股 | 0.0041 | -7.68 | -69.75 |
|
Geode Capital Management, Llc
|
29.55万股 | 0.04 | 3.25 | 12.38 |
|
Goldman Sachs Group Inc
|
4.58万股 | 0.0056 | -2.43 | -34.67 |
|
Hrt Financial Lp
|
20.68万股 | 0.03 | 20.68 | 不足0.01 |
|
Millennium Management Llc
|
9.14万股 | 0.01 | 3.50 | 62.07 |
|
Northern Trust Corp
|
5.92万股 | 0.0072 | - | 不足0.01 |
|
Renaissance Technologies Llc
|
35.60万股 | 0.04 | 1.41 | 4.12 |
|
Redmile Group, Llc
|
44.27万股 | 0.05 | - | 不足0.01 |
|
State Street Corp
|
8.93万股 | 0.01 | -0.22 | -2.40 |
|
Susquehanna International Group, Llp
|
10.47万股 | 0.01 | 10.47 | 不足0.01 |
|
Vanguard Group Inc
|
90.93万股 | 0.11 | -41.96 | -31.58 |
| 机构或基金名称 | 持有数量 | 持股市值(亿美元) | 持股变动(万股) | 变动比例(%) |
|---|---|---|---|---|
|
Acadian Asset Management Llc
|
4.41万股 | 0.0054 | - | 不足0.01 |
|
Aisling Capital Management Lp
|
38.77万股 | 0.05 | - | 不足0.01 |
|
Baker Bros. ADVISORS LP
|
217.75万股 | 0.27 | -135.53 | -38.36 |
|
Blackrock Inc.
|
63.80万股 | 0.08 | -54.77 | -46.19 |
|
Bill & Melinda Gates Foundation
|
91.26万股 | 0.11 | - | 不足0.01 |
|
Barclays Plc
|
4.75万股 | 0.0058 | - | 不足0.01 |
|
Bridgeway Capital Management, Llc
|
7.50万股 | 0.0092 | -7.50 | -50.00 |
|
Boxer Capital, Llc
|
220.23万股 | 0.27 | - | 不足0.01 |
|
Ensign Peak Advisors, Inc
|
10.53万股 | 0.01 | - | 不足0.01 |
|
Geode Capital Management, Llc
|
29.55万股 | 0.04 | 3.25 | 12.38 |
|
Fmr Llc
|
3.33万股 | 0.0041 | -7.68 | -69.75 |
|
Goldman Sachs Group Inc
|
4.58万股 | 0.0056 | -2.43 | -34.67 |
|
Hrt Financial Lp
|
20.68万股 | 0.03 | 20.68 | 不足0.01 |
|
Millennium Management Llc
|
9.14万股 | 0.01 | 3.50 | 62.07 |
|
Northern Trust Corp
|
5.92万股 | 0.0072 | - | 不足0.01 |
|
Redmile Group, Llc
|
44.27万股 | 0.05 | - | 不足0.01 |
|
Renaissance Technologies Llc
|
35.60万股 | 0.04 | 1.41 | 4.12 |
|
Susquehanna International Group, Llp
|
10.47万股 | 0.01 | 10.47 | 不足0.01 |
|
State Street Corp
|
8.93万股 | 0.01 | -0.22 | -2.40 |
|
Vanguard Group Inc
|
90.93万股 | 0.11 | -41.96 | -31.58 |
| 机构或基金名称 | 持有数量 | 持股市值(亿美元) | 持股变动(万股) | 变动比例(%) |
|---|---|---|---|---|
|
Acadian Asset Management Llc
|
4.41万股 | 0.0054 | - | 不足0.01 |
|
Aisling Capital Management Lp
|
38.77万股 | 0.05 | - | 不足0.01 |
|
Baker Bros. ADVISORS LP
|
217.75万股 | 0.27 | -135.53 | -38.36 |
|
Barclays Plc
|
4.75万股 | 0.0058 | - | 不足0.01 |
|
Blackrock Inc.
|
63.80万股 | 0.08 | -54.77 | -46.19 |
|
Bill & Melinda Gates Foundation
|
91.26万股 | 0.11 | - | 不足0.01 |
|
Boxer Capital, Llc
|
220.23万股 | 0.27 | - | 不足0.01 |
|
Bridgeway Capital Management, Llc
|
7.50万股 | 0.0092 | -7.50 | -50.00 |
|
Ensign Peak Advisors, Inc
|
10.53万股 | 0.01 | - | 不足0.01 |
|
Geode Capital Management, Llc
|
29.55万股 | 0.04 | 3.25 | 12.38 |
|
Fmr Llc
|
3.33万股 | 0.0041 | -7.68 | -69.75 |
|
Goldman Sachs Group Inc
|
4.58万股 | 0.0056 | -2.43 | -34.67 |
|
Hrt Financial Lp
|
20.68万股 | 0.03 | 20.68 | 不足0.01 |
|
Millennium Management Llc
|
9.14万股 | 0.01 | 3.50 | 62.07 |
|
Northern Trust Corp
|
5.92万股 | 0.0072 | - | 不足0.01 |
|
Renaissance Technologies Llc
|
35.60万股 | 0.04 | 1.41 | 4.12 |
|
Redmile Group, Llc
|
44.27万股 | 0.05 | - | 不足0.01 |
|
State Street Corp
|
8.93万股 | 0.01 | -0.22 | -2.40 |
|
Susquehanna International Group, Llp
|
10.47万股 | 0.01 | 10.47 | 不足0.01 |
|
Vanguard Group Inc
|
90.93万股 | 0.11 | -41.96 | -31.58 |
| 机构或基金名称 | 持有数量 | 持股市值(亿美元) | 持股变动(万股) | 变动比例(%) |
|---|---|---|---|---|
|
Aisling Capital Management Lp
|
38.77万股 | 0.05 | - | 不足0.01 |
|
Acadian Asset Management Llc
|
4.41万股 | 0.0054 | - | 不足0.01 |
|
Baker Bros. ADVISORS LP
|
217.75万股 | 0.27 | -135.53 | -38.36 |
|
Blackrock Inc.
|
63.80万股 | 0.08 | -54.77 | -46.19 |
|
Bill & Melinda Gates Foundation
|
91.26万股 | 0.11 | - | 不足0.01 |
|
Barclays Plc
|
4.75万股 | 0.0058 | - | 不足0.01 |
|
Boxer Capital, Llc
|
220.23万股 | 0.27 | - | 不足0.01 |
|
Bridgeway Capital Management, Llc
|
7.50万股 | 0.0092 | -7.50 | -50.00 |
|
Ensign Peak Advisors, Inc
|
10.53万股 | 0.01 | - | 不足0.01 |
|
Fmr Llc
|
3.33万股 | 0.0041 | -7.68 | -69.75 |
|
Geode Capital Management, Llc
|
29.55万股 | 0.04 | 3.25 | 12.38 |
|
Goldman Sachs Group Inc
|
4.58万股 | 0.0056 | -2.43 | -34.67 |
|
Hrt Financial Lp
|
20.68万股 | 0.03 | 20.68 | 不足0.01 |
|
Millennium Management Llc
|
9.14万股 | 0.01 | 3.50 | 62.07 |
|
Northern Trust Corp
|
5.92万股 | 0.0072 | - | 不足0.01 |
|
Redmile Group, Llc
|
44.27万股 | 0.05 | - | 不足0.01 |
|
Renaissance Technologies Llc
|
35.60万股 | 0.04 | 1.41 | 4.12 |
|
State Street Corp
|
8.93万股 | 0.01 | -0.22 | -2.40 |
|
Susquehanna International Group, Llp
|
10.47万股 | 0.01 | 10.47 | 不足0.01 |
|
Vanguard Group Inc
|
90.93万股 | 0.11 | -41.96 | -31.58 |
| 机构或基金名称 | 持有数量 | 持股市值(亿美元) | 持股变动(万股) | 变动比例(%) |
|---|---|---|---|---|
|
Aisling Capital Management Lp
|
38.77万股 | 0.05 | - | 不足0.01 |
|
Acadian Asset Management Llc
|
4.41万股 | 0.0054 | - | 不足0.01 |
|
Baker Bros. ADVISORS LP
|
217.75万股 | 0.27 | -135.53 | -38.36 |
|
Blackrock Inc.
|
63.80万股 | 0.08 | -54.77 | -46.19 |
|
Bill & Melinda Gates Foundation
|
91.26万股 | 0.11 | - | 不足0.01 |
|
Barclays Plc
|
4.75万股 | 0.0058 | - | 不足0.01 |
|
Bridgeway Capital Management, Llc
|
7.50万股 | 0.0092 | -7.50 | -50.00 |
|
Boxer Capital, Llc
|
220.23万股 | 0.27 | - | 不足0.01 |
|
Ensign Peak Advisors, Inc
|
10.53万股 | 0.01 | - | 不足0.01 |
|
Fmr Llc
|
3.33万股 | 0.0041 | -7.68 | -69.75 |
|
Geode Capital Management, Llc
|
29.55万股 | 0.04 | 3.25 | 12.38 |
|
Goldman Sachs Group Inc
|
4.58万股 | 0.0056 | -2.43 | -34.67 |
|
Hrt Financial Lp
|
20.68万股 | 0.03 | 20.68 | 不足0.01 |
|
Millennium Management Llc
|
9.14万股 | 0.01 | 3.50 | 62.07 |
|
Northern Trust Corp
|
5.92万股 | 0.0072 | - | 不足0.01 |
|
Renaissance Technologies Llc
|
35.60万股 | 0.04 | 1.41 | 4.12 |
|
Redmile Group, Llc
|
44.27万股 | 0.05 | - | 不足0.01 |
|
State Street Corp
|
8.93万股 | 0.01 | -0.22 | -2.40 |
|
Susquehanna International Group, Llp
|
10.47万股 | 0.01 | 10.47 | 不足0.01 |
|
Vanguard Group Inc
|
90.93万股 | 0.11 | -41.96 | -31.58 |