股本结构
单位：万股
| 公告日期 | 2025-05-14 | 2025-05-14 | 2025-03-27 | 2025-02-21 | 2025-03-27 | 2024-12-04 |
|---|---|---|---|---|---|---|
| 证券总股本 | 979.25 | 979.00 | 979.01 | 974.09 | 972.80 | 972.22 |
| 普通股本 | 979.25 | 979.00 | 979.01 | 974.09 | 972.80 | 972.22 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-05-09 | 2025-03-31 | 2025-03-21 | 2025-02-18 | 2024-12-31 | 2024-12-13 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-05-14 | 979.25 | 未披露 | 定期报告 | 2025-05-09 |
| 2025-05-14 | 979.00 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Vesting of restricted stock units
|
2025-03-31 |
| 2025-03-27 | 979.01 | 未披露 | 定期报告 | 2025-03-21 |
| 2025-02-21 | 974.09 | 未披露 | 定期报告 | 2025-02-18 |
| 2025-03-27 | 972.80 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Purchase of shares under ESPP
Vesting of restricted stock
|
2024-12-31 |
| 2024-12-04 | 972.22 | 未披露 |
更多>>
a 1-for-20 reverse stock split of the Company’s common stock
|
2024-12-13 |
| 2024-11-14 | 19444.43 | 未披露 | 定期报告 | 2024-11-12 |
| 2024-11-14 | 19391.70 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Vesting of restricted stock units
|
2024-09-30 |
| 2024-09-13 | 19391.36 | 未披露 | 定期报告 | 2024-09-11 |
| 2024-09-27 | 19385.60 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Vesting of restricted stock units
Purchase of common stock under employee stock purchase plan
|
2024-06-30 |
| 2024-09-13 | 19358.30 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Vesting of restricted stock units
|
2024-03-31 |
| 2024-09-13 | 19277.20 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Vesting of restricted stock
Exercise of stock options
Issuance of common stock
Exercise of warrants
Purchase of shares under ESPP
|
2023-12-31 |
| 2023-12-20 | 19274.19 | 未披露 |
更多>>
Common stock offered 83,333,333 shares by the company
|
2023-12-22 |
| 2023-12-18 | 10940.86 | 未披露 | 定期报告 | 2023-11-30 |
| 2023-11-07 | 10933.62 | 未披露 | 定期报告 | 2023-11-03 |
| 2023-12-18 | 10702.21 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Exercise of stock options
Vesting of restricted stock units
Issuance of common stock
|
2023-09-30 |
| 2023-08-08 | 10695.27 | 未披露 | 定期报告 | 2023-08-04 |
| 2023-08-08 | 10645.39 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Exercise of stock options
Vesting of restricted stock units
|
2023-06-30 |
| 2023-05-09 | 10641.20 | 未披露 | 定期报告 | 2023-05-05 |
| 2023-04-28 | 10638.35 | 未披露 | 定期报告 | 2023-04-24 |
| 2023-03-29 | 10637.03 | 未披露 | 定期报告 | 2023-03-27 |
| 2023-01-19 | 10292.33 | 未披露 |
更多>>
Common stock offered 20,000,000 shares by the company
|
2023-01-23 |
| 2023-03-29 | 8292.33 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Purchase of common stock under ESPP
Issuance of unrestricted stock awards to settle accrued employee compensation
Vesting of restricted stock units
Issuance of common stock for private equity placement
Exercise of stock options
|
2022-12-31 |
| 2022-11-07 | 8291.00 | 未披露 | 定期报告 | 2022-11-03 |
| 2022-11-07 | 8288.00 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Purchase of common stock under ESPP
Vesting of restricted stock units
Issuance of common stock
|
2022-09-30 |
| 2022-08-04 | 7712.18 | 未披露 | 定期报告 | 2022-08-03 |
| 2022-08-04 | 7355.10 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Vesting of restricted stock units
Issuance of common stock
Exercise of stock options
|
2022-06-30 |
| 2022-05-09 | 7145.37 | 未披露 | 定期报告 | 2022-05-04 |
| 2022-05-02 | 7144.69 | 未披露 | 定期报告 | 2022-04-25 |
| 2022-05-09 | 7143.80 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Vesting of restricted stock units
Exercise of stock options
Issuance of unrestricted stock awards to settle accrued employee compensation
|
2022-03-31 |
| 2022-03-04 | 7143.33 | 未披露 | 定期报告 | 2022-02-28 |
| 2022-03-04 | 7111.50 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock for private equity placement
Issuance of unrestricted stock awards to settle accrued employee compensation
|
2021-12-31 |
| 2021-11-05 | 7010.73 | 未披露 | 定期报告 | 2021-11-01 |
| 2021-11-05 | 7009.70 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock for private equity placement
Issuance of unrestricted stock awards to settle accrued employee compensation
|
2021-09-30 |
| 2021-08-09 | 6757.85 | 未披露 | 定期报告 | 2021-08-03 |
| 2021-08-09 | 6755.10 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Vesting of restricted stock units
Exercise of stock options
|
2021-06-30 |
| 2021-04-30 | 6744.75 | 未披露 | 定期报告 | 2021-04-19 |
| 2021-05-05 | 6742.20 | 未披露 |
更多>>
from December 31, 2020 to March 31, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of unrestricted stock awards to settle accrued employee compensation
|
2021-03-31 |
| 2021-02-23 | 6714.10 | 未披露 | 定期报告 | 2021-02-18 |
| 2021-02-23 | 6643.20 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock upon public offering, net of issuance costs of $33,645
|
2020-12-31 |
| 2020-11-04 | 6637.33 | 未披露 | 定期报告 | 2020-10-30 |
| 2020-11-04 | 6633.90 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
|
2020-09-30 |
| 2020-08-05 | 6622.30 | 未披露 | 定期报告 | 2020-07-31 |
| 2020-08-05 | 6619.60 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock upon public offering,net of issuance costs of $33,465
Vesting of restricted stock units
Exercise of stock options
|
2020-06-30 |
| 2020-05-11 | 5565.21 | 未披露 | 定期报告 | 2020-05-05 |
| 2020-04-27 | 5563.75 | 未披露 | 定期报告 | 2020-04-23 |
| 2020-05-11 | 5562.00 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
|
2020-03-31 |
| 2020-02-18 | 5561.16 | 未披露 | 定期报告 | 2020-02-13 |
| 2020-02-18 | 5536.80 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
|
2019-12-31 |
| 2019-10-31 | 5533.10 | 未披露 | 定期报告 | 2019-10-25 |
| 2019-10-31 | 5532.00 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
|
2019-09-30 |
| 2019-08-01 | 5526.92 | 未披露 | 定期报告 | 2019-07-25 |
| 2019-08-01 | 5522.80 | 未披露 |
更多>>
from March 31, 2019 to June 30,2019
Vesting of restricted stock units
Exercise of stock options
|
2019-06-30 |
| 2019-05-03 | 5512.33 | 未披露 | 定期报告 | 2019-04-26 |
| 2019-04-23 | 5511.72 | 未披露 | 定期报告 | 2019-04-15 |
| 2019-05-03 | 5506.90 | 未披露 |
更多>>
From December 31, 2018 to March 31, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
|
2019-03-31 |
| 2019-02-21 | 5495.12 | 未披露 | 定期报告 | 2019-02-15 |
| 2019-02-21 | 5473.80 | 未披露 |
更多>>
From December 31, 2017 to December 31, 2018
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $34,588
Issuance of common stock to Regeneron
Exercise of stock options
Purchase of common stock under ESPP
|
2018-12-31 |
| 2018-11-01 | 5469.44 | 未披露 | 定期报告 | 2018-10-26 |
| 2018-11-01 | 5467.80 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-02 | 5415.79 | 未披露 | 定期报告 | 2018-07-27 |
| 2018-08-02 | 5022.50 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-02 | 5011.93 | 未披露 | 定期报告 | 2018-04-27 |
| 2018-04-27 | 5011.78 | 未披露 | 定期报告 | 2018-04-23 |
| 2018-05-02 | 5006.70 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-02-21 | 4998.35 | 未披露 | 定期报告 | 2018-02-16 |
| 2018-02-21 | 4940.60 | 未披露 |
更多>>
From December 31, 2016 to December 31, 2017
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $53,487
Exercise of stock options
Purchase of common stock under ESPP
|
2017-12-31 |
| 2017-11-01 | 4583.09 | 未披露 | 定期报告 | 2017-10-27 |
| 2017-11-01 | 4578.50 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-02 | 4558.94 | 未披露 | 定期报告 | 2017-07-28 |
| 2017-08-02 | 4553.90 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-05-03 | 4095.01 | 未披露 | 定期报告 | 2017-04-28 |
| 2017-04-21 | 4093.96 | 未披露 | 定期报告 | 2017-04-13 |
| 2017-05-03 | 4092.30 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-02-22 | 4084.48 | 未披露 | 定期报告 | 2017-02-17 |
| 2017-02-22 | 4069.10 | 未披露 |
更多>>
from December 31, 2015 to December 31, 2016
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $15,269
Exercise of stock options
Purchase of common stock under ESPP
|
2016-12-31 |
| 2016-11-02 | 3730.37 | 未披露 | 定期报告 | 2016-10-28 |
| 2016-11-02 | 3729.60 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-03 | 3717.00 | 未披露 | 定期报告 | 2016-07-29 |
| 2016-08-03 | 3700.20 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-05-04 | 3694.30 | 未披露 | 定期报告 | 2016-04-30 |
| 2016-04-21 | 3694.20 | 未披露 | 定期报告 | 2016-04-08 |
| 2016-05-04 | 3693.70 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-02-25 | 3692.76 | 未披露 | 定期报告 | 2016-02-18 |
| 2016-02-25 | 3689.40 | 未披露 |
更多>>
From December 31, 2014 to December 31, 2015
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $22,753
Issuance of common stock to Pregenen equityholders
Exercise of common stock warrants
Exercise of stock options
Purchase of common stock under ESPP
|
2015-12-31 |
| 2015-11-05 | 3667.69 | 未披露 | 定期报告 | 2015-10-30 |
| 2015-11-05 | 3664.10 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-07 | 3626.36 | 未披露 | 定期报告 | 2015-07-31 |
| 2015-08-07 | 3595.80 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-05-06 | 3282.94 | 未披露 | 定期报告 | 2015-04-28 |
| 2015-04-24 | 3277.65 | 未披露 | 定期报告 | 2015-04-10 |
| 2015-05-06 | 3269.30 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-02-25 | 3256.63 | 未披露 | 定期报告 | 2015-02-18 |
| 2015-02-25 | 3234.00 | 未披露 |
更多>>
from December 31, 2013 to December 31, 2014
Vesting of restricted stock issued in exchange for nonrecourse note
Issuance of common stock upon public offering,net of issuance costs of $23,295
Issuance of common stock in connection with acquisition
Exercise of common stock warrants
Exercise of stock options
Issuance of common stock in exchange for consulting services to non-employees
|
2014-12-31 |
| 2014-11-12 | 2882.25 | 未披露 | 定期报告 | 2014-11-06 |
| 2014-11-12 | 2870.20 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-12 | 2859.58 | 未披露 | 定期报告 | 2014-07-29 |
| 2014-08-12 | 2507.70 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-05-13 | 2451.20 | 未披露 | 定期报告 | 2014-05-08 |
| 2014-04-24 | 2436.43 | 未披露 | 定期报告 | 2014-04-21 |
| 2014-05-13 | 2427.90 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-03-05 | 2416.95 | 未披露 | 定期报告 | 2014-02-24 |
| 2014-03-05 | 2394.00 | 未披露 |
更多>>
from December 31, 2012 to December 31, 2013
Vesting of restricted stock issued in exchange for nonrecourse note
Vesting of restricted stock
Proceeds from IPO, net of closing costs of $11,229
Conversion of convertible preferred stock into common stock
Exercise of common stock warrants
Exercise of stock options
On June 3, 2013, the board of directors and the stockholders of the Company approved a one-for-18.967 reverse stock split of the Company’s outstanding common stock, which was effected on June 3, 2013.
|
2013-12-31 |
| 2013-11-14 | 2378.02 | 未披露 | 定期报告 | 2013-10-31 |
| 2013-11-14 | 2363.30 | 未披露 | 定期报告 | 2013-09-30 |
| 2013-08-14 | 2372.12 | 未披露 | 定期报告 | 2013-07-29 |
| 2013-08-14 | 2360.30 | 未披露 |
更多>>
Upon the closing of the IPO, all outstanding shares of convertible preferred stock converted into 16,388,510 shares of common stock; and warrants exercisable for convertible preferred stock were automatically converted into warrants exercisable for 337,952 shares of common stock, resulting in the reclassification of the related convertible preferred stock warrant liability of approximately $0.7 million to additional paid-in capital. Additionally, we are now authorized to issue 125,000,000 shares of common stock and 5,000,000 shares of preferred stock.
|
2013-06-30 |
| 2013-06-19 | 2281.07 | 未披露 |
更多>>
reflects the conversion of all of our outstanding shares of preferred stock into an aggregate of 16,388,510 shares of common stock upon the closing of this offering;
reflects a one-for-18.967 reverse stock split of our common stock that became effective on June 3, 2013.
|
2013-06-19 |
| 2013-06-04 | 34.80 | 31084.10 |
更多>>
On June 3, 2013, the board of directors and the stockholders of the Company approved a one-for-18.967 reverse stock split of the Company’s outstanding common stock, which was effected on June 3, 2013.
|
2013-06-03 |
| 2013-05-14 | 659.90 | 31084.10 |
更多>>
From December 31,2012 to March 31,2013
Vesting of restricted stock issued in exchange for nonrecourse note
Vesting of restricted stock
Exercise of stock options
|
2013-03-31 |
From December 31, 2024 to March 31, 2025
Vesting of restricted stock units
From December 31, 2023 to December 31, 2024
Purchase of shares under ESPP
Vesting of restricted stock
a 1-for-20 reverse stock split of the Company’s common stock
From June 30, 2024 to September 30, 2024
Vesting of restricted stock units
From March 31, 2024 to June 30, 2024
Vesting of restricted stock units
Purchase of common stock under employee stock purchase plan
From December 31, 2023 to March 31, 2024
Vesting of restricted stock units
From December 31, 2022 to December 31, 2023
Vesting of restricted stock
Exercise of stock options
Issuance of common stock
Exercise of warrants
Purchase of shares under ESPP
Common stock offered 83,333,333 shares by the company
From June 30, 2023 to September 30, 2023
Exercise of stock options
Vesting of restricted stock units
Issuance of common stock
From March 31, 2023 to June 30, 2023
Exercise of stock options
Vesting of restricted stock units
Common stock offered 20,000,000 shares by the company
From December 31, 2021 to December 31, 2022
Purchase of common stock under ESPP
Issuance of unrestricted stock awards to settle accrued employee compensation
Vesting of restricted stock units
Issuance of common stock for private equity placement
Exercise of stock options
From June 30, 2022 to September 30, 2022
Purchase of common stock under ESPP
Vesting of restricted stock units
Issuance of common stock
From March 31, 2022 to June 30, 2022
Vesting of restricted stock units
Issuance of common stock
Exercise of stock options
From December 31, 2021 to March 31, 2022
Vesting of restricted stock units
Exercise of stock options
Issuance of unrestricted stock awards to settle accrued employee compensation
From December 31, 2020 to December 31, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock for private equity placement
Issuance of unrestricted stock awards to settle accrued employee compensation
From June 30, 2021 to September 30, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock for private equity placement
Issuance of unrestricted stock awards to settle accrued employee compensation
From March 31, 2021 to June 30, 2021
Vesting of restricted stock units
Exercise of stock options
from December 31, 2020 to March 31, 2021
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of unrestricted stock awards to settle accrued employee compensation
From December 31,2019 to December 31,2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
Issuance of common stock upon public offering, net of issuance costs of $33,645
From June 30, 2020 to September 30, 2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
From March 31, 2020 to June 30, 2020
Issuance of common stock upon public offering,net of issuance costs of $33,465
Vesting of restricted stock units
Exercise of stock options
From December 31, 2019 to March 31, 2020
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2018 to December 31, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
from June 30, 2019 to September 30, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
from March 31, 2019 to June 30,2019
Vesting of restricted stock units
Exercise of stock options
From December 31, 2018 to March 31, 2019
Vesting of restricted stock units
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2017 to December 31, 2018
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $34,588
Issuance of common stock to Regeneron
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2016 to December 31, 2017
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $53,487
Exercise of stock options
Purchase of common stock under ESPP
from December 31, 2015 to December 31, 2016
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $15,269
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2014 to December 31, 2015
Vesting of restricted stock units
Issuance of common stock upon public offering, net of issuance costs of $22,753
Issuance of common stock to Pregenen equityholders
Exercise of common stock warrants
Exercise of stock options
Purchase of common stock under ESPP
from December 31, 2013 to December 31, 2014
Vesting of restricted stock issued in exchange for nonrecourse note
Issuance of common stock upon public offering,net of issuance costs of $23,295
Issuance of common stock in connection with acquisition
Exercise of common stock warrants
Exercise of stock options
Issuance of common stock in exchange for consulting services to non-employees
from December 31, 2012 to December 31, 2013
Vesting of restricted stock issued in exchange for nonrecourse note
Vesting of restricted stock
Proceeds from IPO, net of closing costs of $11,229
Conversion of convertible preferred stock into common stock
Exercise of common stock warrants
Exercise of stock options
On June 3, 2013, the board of directors and the stockholders of the Company approved a one-for-18.967 reverse stock split of the Company’s outstanding common stock, which was effected on June 3, 2013.
Upon the closing of the IPO, all outstanding shares of convertible preferred stock converted into 16,388,510 shares of common stock; and warrants exercisable for convertible preferred stock were automatically converted into warrants exercisable for 337,952 shares of common stock, resulting in the reclassification of the related convertible preferred stock warrant liability of approximately $0.7 million to additional paid-in capital. Additionally, we are now authorized to issue 125,000,000 shares of common stock and 5,000,000 shares of preferred stock.
reflects the conversion of all of our outstanding shares of preferred stock into an aggregate of 16,388,510 shares of common stock upon the closing of this offering;
reflects a one-for-18.967 reverse stock split of our common stock that became effective on June 3, 2013.
On June 3, 2013, the board of directors and the stockholders of the Company approved a one-for-18.967 reverse stock split of the Company’s outstanding common stock, which was effected on June 3, 2013.
From December 31,2012 to March 31,2013
Vesting of restricted stock issued in exchange for nonrecourse note
Vesting of restricted stock
Exercise of stock options