股本结构
单位：万股
| 公告日期 | 2025-05-01 | 2025-04-24 | 2025-05-01 | 2025-02-13 | 2025-02-13 | 2024-10-30 |
|---|---|---|---|---|---|---|
| 证券总股本 | 6458.22 | 6457.59 | 6456.39 | 6390.60 | 6371.23 | 6352.58 |
| 普通股本 | 6458.22 | 6457.59 | 6456.39 | 6390.60 | 6371.23 | 6352.58 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-04-29 | 2025-04-21 | 2025-03-31 | 2025-02-11 | 2024-12-31 | 2024-10-28 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-05-01 | 6458.22 | 未披露 | 定期报告 | 2025-04-29 |
| 2025-04-24 | 6457.59 | 未披露 | 定期报告 | 2025-04-21 |
| 2025-05-01 | 6456.39 | 未披露 |
更多>>
From December 31,2024 to March 31,2025
Issuance of common stock under stock plan
|
2025-03-31 |
| 2025-02-13 | 6390.60 | 未披露 | 定期报告 | 2025-02-11 |
| 2025-02-13 | 6371.23 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock under stock plan and stock purchase plan
At-the-market offerings, net of issuance costs
|
2024-12-31 |
| 2024-10-30 | 6352.58 | 未披露 | 定期报告 | 2024-10-28 |
| 2024-10-30 | 6345.47 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock under stock plan
|
2024-09-30 |
| 2024-08-01 | 6334.55 | 未披露 | 定期报告 | 2024-07-30 |
| 2024-08-01 | 6316.57 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock under stock plan and stock purchase plan
|
2024-06-30 |
| 2024-05-02 | 6261.69 | 未披露 | 定期报告 | 2024-04-30 |
| 2024-04-25 | 6281.49 | 未披露 | 定期报告 | 2024-04-12 |
| 2024-05-02 | 6259.42 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock under stock plan
At-the-market offerings, net of issuance costs
|
2024-03-31 |
| 2024-02-15 | 6123.23 | 未披露 | 定期报告 | 2024-02-13 |
| 2024-02-15 | 6114.72 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock under stock plan and stock purchase plan
|
2023-12-31 |
| 2023-10-26 | 6078.97 | 未披露 | 定期报告 | 2023-10-23 |
| 2023-10-26 | 6074.07 | 未披露 |
更多>>
From June 30,2023 to September 30,2023
Issuance of common stock under stock plan
|
2023-09-30 |
| 2023-08-02 | 6066.47 | 未披露 | 定期报告 | 2023-07-28 |
| 2023-08-02 | 6063.83 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock under stock plan and stock purchase plan
|
2023-06-30 |
| 2023-05-04 | 6046.73 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-04-28 | 6044.73 | 未披露 | 定期报告 | 2023-04-24 |
| 2023-05-04 | 6041.63 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock under stock plan
|
2023-03-31 |
| 2023-02-16 | 5998.35 | 未披露 | 定期报告 | 2023-02-14 |
| 2023-02-16 | 5995.89 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2022-12-31 |
| 2022-11-01 | 5983.06 | 未披露 | 定期报告 | 2022-10-28 |
| 2022-11-01 | 5980.85 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock under stock plan
|
2022-09-30 |
| 2022-08-02 | 5971.96 | 未披露 | 定期报告 | 2022-07-29 |
| 2022-08-02 | 5968.83 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2022-06-30 |
| 2022-04-29 | 5957.05 | 未披露 | 定期报告 | 2022-04-25 |
| 2022-05-03 | 5955.60 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock under stock plan
|
2022-03-31 |
| 2022-02-17 | 5920.35 | 未披露 | 定期报告 | 2022-02-15 |
| 2022-02-17 | 5914.11 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2021-12-31 |
| 2021-10-28 | 5883.80 | 未披露 | 定期报告 | 2021-10-25 |
| 2021-10-28 | 5881.47 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock under stock plan
|
2021-09-30 |
| 2021-07-29 | 5857.40 | 未披露 | 定期报告 | 2021-07-26 |
| 2021-07-29 | 5855.46 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2021-06-30 |
| 2021-04-29 | 5834.15 | 未披露 | 定期报告 | 2021-04-26 |
| 2021-04-21 | 5829.31 | 未披露 | 定期报告 | 2021-04-09 |
| 2021-04-29 | 5827.74 | 未披露 |
更多>>
from December 31, 2020 to March 31, 2021
Issuance of common stock under stock plan
|
2021-03-31 |
| 2021-02-17 | 5795.76 | 未披露 | 定期报告 | 2021-02-15 |
| 2021-02-17 | 5779.35 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering and at-the-market offerings, net of issuance costs
Issuance of common stock related to collaboration agreement
|
2020-12-31 |
| 2020-10-29 | 5573.08 | 未披露 | 定期报告 | 2020-10-26 |
| 2020-10-29 | 5551.44 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock under stock plan
|
2020-09-30 |
| 2020-07-31 | 5527.21 | 未披露 | 定期报告 | 2020-07-24 |
| 2020-07-31 | 5428.45 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2020-06-30 |
| 2020-05-06 | 5419.00 | 未披露 | 定期报告 | 2020-04-30 |
| 2020-04-29 | 5418.84 | 未披露 | 定期报告 | 2020-04-24 |
| 2020-05-06 | 5416.85 | 未披露 |
更多>>
from December 31, 2019 to March 31, 2020
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
|
2020-03-31 |
| 2020-02-13 | 5402.70 | 未披露 | 定期报告 | 2020-02-10 |
| 2020-02-13 | 4927.22 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering, net of issuance costs
|
2019-12-31 |
| 2019-11-05 | 4920.21 | 未披露 | 定期报告 | 2019-10-31 |
| 2019-11-05 | 4917.54 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock under stock plan
|
2019-09-30 |
| 2019-08-01 | 4911.56 | 未披露 | 定期报告 | 2019-07-26 |
| 2019-08-01 | 4905.96 | 未披露 |
更多>>
from March 31, 2019 to June 30, 2019
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering, net of issuance costs
|
2019-06-30 |
| 2019-05-09 | 4885.39 | 未披露 | 定期报告 | 2019-05-06 |
| 2019-04-29 | 4884.90 | 未披露 | 定期报告 | 2019-04-22 |
| 2019-05-09 | 4417.15 | 未披露 |
更多>>
from December 31, 2018 to March 31, 2019
Issuance of common stock under stock plan
|
2019-03-31 |
| 2019-02-26 | 4409.94 | 未披露 | 定期报告 | 2019-02-15 |
| 2019-02-26 | 4403.70 | 未披露 |
更多>>
from December 31, 2017 to December 31, 2018
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2018-12-31 |
| 2018-10-30 | 4395.04 | 未披露 | 定期报告 | 2018-10-26 |
| 2018-10-30 | 4394.53 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-01 | 4388.77 | 未披露 | 定期报告 | 2018-07-27 |
| 2018-08-01 | 4388.38 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-02 | 4383.73 | 未披露 | 定期报告 | 2018-04-30 |
| 2018-04-27 | 4383.73 | 未披露 | 定期报告 | 2018-04-23 |
| 2018-05-02 | 4382.12 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-02-21 | 4370.40 | 未披露 | 定期报告 | 2018-02-15 |
| 2018-02-21 | 4357.75 | 未披露 |
更多>>
From December 31, 2016 To December 31, 2017
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2017-12-31 |
| 2017-10-31 | 3917.90 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-02 | 3912.23 | 未披露 | 定期报告 | 2017-07-31 |
| 2017-08-02 | 3908.02 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-05-03 | 3901.84 | 未披露 | 定期报告 | 2017-05-01 |
| 2017-04-28 | 3901.64 | 未披露 | 定期报告 | 2017-04-24 |
| 2017-05-03 | 3324.94 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-03-09 | 3320.39 | 未披露 | 定期报告 | 2017-02-28 |
| 2017-03-09 | 3312.34 | 未披露 |
更多>>
from December 31, 2015 to December 31, 2016
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
Purchase of common stock under ESPP
|
2016-12-31 |
| 2016-11-10 | 2732.72 | 未披露 | 定期报告 | 2016-11-08 |
| 2016-11-10 | 2729.39 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-09 | 2728.18 | 未披露 | 定期报告 | 2016-08-08 |
| 2016-08-09 | 2722.74 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-05-10 | 2723.87 | 未披露 | 定期报告 | 2016-05-06 |
| 2016-04-28 | 2723.80 | 未披露 | 定期报告 | 2016-04-25 |
| 2016-05-10 | 2714.16 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-03-11 | 2720.13 | 未披露 | 定期报告 | 2016-02-29 |
| 2016-03-11 | 2706.56 | 未披露 |
更多>>
From December 31, 2014 to December 31, 2015
Conversion of preferred stock into common stock
Initial public offering, net of issuance costs
Issuance of common stock upon warrant exercise
Issuance of common stock under stock plan
On April 10, 2015, one-for-5.5 reverse stock split of the company's common stock effected
|
2015-12-31 |
| 2015-11-09 | 2710.08 | 未披露 | 定期报告 | 2015-11-02 |
| 2015-11-09 | 2689.56 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-10 | 2711.21 | 未披露 | 定期报告 | 2015-08-06 |
| 2015-08-10 | 2669.19 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-06-11 | 2711.14 | 未披露 | 定期报告 | 2015-06-10 |
| 2015-04-30 | 2583.20 | 未披露 |
更多>>
1. the automatic conversion of all of our outstanding shares of convertible preferred stock into an aggregate of 15,467,479 shares of common stock upon the completion of this offering;
2. a one-for-5.5 reverse stock split of our common stock effected on April 10, 2015.
|
2015-04-30 |
| 2015-06-11 | 173.14 | 8507.13 | 定期报告 | 2015-03-31 |
| 2015-04-20 | 162.67 | 8507.13 |
更多>>
From December 31, 2013 to December 31, 2014
Issuance of Series B convertible preferred stock at $1.20 per share, net of issuance costs of $115
Issuance of Series C convertible preferred stock at $2.07 per share, net of issuance costs of $131
Issuance of common stock under stock plan
|
2014-12-31 |
From December 31,2024 to March 31,2025
Issuance of common stock under stock plan
From December 31, 2023 to December 31, 2024
Issuance of common stock under stock plan and stock purchase plan
At-the-market offerings, net of issuance costs
From June 30, 2024 to September 30, 2024
Issuance of common stock under stock plan
From March 31, 2024 to June 30, 2024
Issuance of common stock under stock plan and stock purchase plan
From December 31, 2023 to March 31, 2024
Issuance of common stock under stock plan
At-the-market offerings, net of issuance costs
From December 31, 2022 to December 31, 2023
Issuance of common stock under stock plan and stock purchase plan
From June 30,2023 to September 30,2023
Issuance of common stock under stock plan
From March 31, 2023 to June 30, 2023
Issuance of common stock under stock plan and stock purchase plan
From December 31, 2022 to March 31, 2023
Issuance of common stock under stock plan
From December 31, 2021 to December 31, 2022
Issuance of common stock under stock plan
Purchase of common stock under ESPP
From June 30, 2022 to September 30, 2022
Issuance of common stock under stock plan
From March 31, 2022 to June 30, 2022
Issuance of common stock under stock plan
Purchase of common stock under ESPP
From December 31, 2021 to March 31, 2022
Issuance of common stock under stock plan
From December 31, 2020 to December 31, 2021
Issuance of common stock under stock plan
Purchase of common stock under ESPP
From June 30, 2021 to September 30, 2021
Issuance of common stock under stock plan
From March 31, 2021 to June 30, 2021
Issuance of common stock under stock plan
Purchase of common stock under ESPP
from December 31, 2020 to March 31, 2021
Issuance of common stock under stock plan
From December 31,2019 to December 31,2020
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering and at-the-market offerings, net of issuance costs
Issuance of common stock related to collaboration agreement
From June 30, 2020 to September 30, 2020
Issuance of common stock under stock plan
From March 31, 2020 to June 30, 2020
Issuance of common stock under stock plan
Purchase of common stock under ESPP
from December 31, 2019 to March 31, 2020
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
from December 31, 2018 to December 31, 2019
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering, net of issuance costs
from June 30, 2019 to September 30, 2019
Issuance of common stock under stock plan
from March 31, 2019 to June 30, 2019
Issuance of common stock under stock plan
Purchase of common stock under ESPP
Follow on offering, net of issuance costs
from December 31, 2018 to March 31, 2019
Issuance of common stock under stock plan
from December 31, 2017 to December 31, 2018
Issuance of common stock under stock plan
Purchase of common stock under ESPP
From December 31, 2016 To December 31, 2017
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
Purchase of common stock under ESPP
from December 31, 2015 to December 31, 2016
Follow on offering, net of issuance costs
Issuance of common stock under stock plan
Purchase of common stock under ESPP
From December 31, 2014 to December 31, 2015
Conversion of preferred stock into common stock
Initial public offering, net of issuance costs
Issuance of common stock upon warrant exercise
Issuance of common stock under stock plan
On April 10, 2015, one-for-5.5 reverse stock split of the company's common stock effected
1. the automatic conversion of all of our outstanding shares of convertible preferred stock into an aggregate of 15,467,479 shares of common stock upon the completion of this offering;
2. a one-for-5.5 reverse stock split of our common stock effected on April 10, 2015.
From December 31, 2013 to December 31, 2014
Issuance of Series B convertible preferred stock at $1.20 per share, net of issuance costs of $115
Issuance of Series C convertible preferred stock at $2.07 per share, net of issuance costs of $131
Issuance of common stock under stock plan