股本结构

单位:万股
公告日期 2025-11-10 2025-11-10 2025-08-07 2025-08-07 2025-05-08 2025-05-08
证券总股本 6644.95 6644.68 6640.65 6639.42 6639.42 6638.42
普通股本 6644.95 6644.68 6640.65 6639.42 6639.42 6638.42
优先股 未披露 未披露 未披露 未披露 未披露 未披露
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2025-10-29 2025-09-30 2025-07-28 2025-06-30 2025-04-30 2025-03-31
注释:中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本(万股) 变动后优先股(万股) 变动原因 变动日期
2025-11-10 6644.95 未披露 定期报告 2025-10-29
2025-11-10 6644.68 未披露
更多>>
From June 30, 2025 to September 30, 2025 Shares issued under stock option and employee stock purchase plans
2025-09-30
2025-08-07 6640.65 未披露 定期报告 2025-07-28
2025-08-07 6639.42 未披露
更多>>
From March 31, 2025 to June 30, 2025 Shares issued under stock option and employee stock purchase plans
2025-06-30
2025-05-08 6639.42 未披露 定期报告 2025-04-30
2025-05-08 6638.42 未披露
更多>>
From December 31, 2024 to March 31, 2025 Shares issued under stock option and employee stock purchase plans
2025-03-31
2025-02-27 6638.38 未披露 定期报告 2025-02-14
2025-02-27 6637.45 未披露
更多>>
From December 31, 2023 to December 31, 2024 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
2024-12-31
2024-11-06 6634.42 未披露
更多>>
From June 30, 2024 to September 30, 2024 Shares issued under stock option and employee stock purchase plans
2024-09-30
2024-08-08 6628.76 未披露 定期报告 2024-07-31
2024-08-08 6628.07 未披露
更多>>
From March 31, 2024 to June 30, 2024 Shares issued under stock option and employee stock purchase plans
2024-06-30
2024-05-06 6591.05 未披露
更多>>
From December 31, 2023 to March 31, 2024 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
2024-03-31
2024-03-01 6442.07 未披露
更多>>
Common stock offered 8,520,000 shares by the company
2024-03-05
2024-02-26 5590.07 未披露 定期报告 2024-02-14
2024-02-26 5588.34 未披露
更多>>
From December 31, 2022 to December 31, 2023 Shares issued in underwritten offering, net Shares issued under stock option and employee stock purchase plans
2023-12-31
2023-11-08 5468.92 未披露
更多>>
Common stock offered 7,425,000 shares by the company
2023-11-10
2023-11-02 4726.42 未披露
更多>>
From June 30, 2023 to September 30, 2023 Shares issued under stock option and employee stock purchase plans
2023-09-30
2023-08-08 4726.08 未披露 定期报告 2023-07-31
2023-04-25 4725.25 未披露 定期报告 2023-04-18
2023-04-25 4725.19 未披露 定期报告 2023-04-05
2023-05-04 4724.47 未披露
更多>>
From December 31, 2022 to March 31, 2023 Shares issued under stock option and employee stock purchase plans
2023-03-31
2023-02-28 4720.72 未披露 定期报告 2023-02-13
2023-02-28 4720.07 未披露
更多>>
From December 31, 2021 to December 31, 2022 Shares issued under stock option and employee stock purchase plans
2022-12-31
2022-11-09 4709.98 未披露 定期报告 2022-10-31
2022-11-09 4709.61 未披露
更多>>
From June 30, 2022 to September 30, 2022 Shares issued under stock option and employee stock purchase plans
2022-09-30
2022-08-08 4677.24 未披露 定期报告 2022-07-29
2022-08-08 4676.47 未披露
更多>>
From March 31, 2022 to June 30, 2022 Shares issued under stock option and employee stock purchase plans
2022-06-30
2022-05-05 4675.43 未披露
更多>>
From December 31, 2021 to March 31, 2022 Shares issued under stock option and employee stock purchase plans
2022-03-31
2022-02-28 4673.50 未披露 定期报告 2022-02-17
2022-02-28 4673.02 未披露
更多>>
From December 31, 2020 to December 31, 2021 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
2021-12-31
2021-11-09 4666.39 未披露 定期报告 2021-10-31
2021-11-09 4666.33 未披露
更多>>
From June 30, 2021 to September 30, 2021 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
2021-09-30
2021-08-05 4648.18 未披露 定期报告 2021-07-31
2021-07-16 4556.70 未披露
更多>>
1.Common stock offered 5,952,381 shares. 2.The number of shares of common stock to be outstanding after this offering is based on 39,614,638 shares of common stock outstanding as of March 31, 2021.
2021-07-16
2021-08-05 3961.67 未披露
更多>>
From March 31, 2021 to June 30, 2021 Shares issued under stock option and employee stock purchase plans
2021-06-30
2021-05-06 3961.46 未披露
更多>>
from December 31, 2020 to March 31, 2021 Shares issued under stock option and employee stock purchase plans
2021-03-31
2021-03-29 3961.46 未披露 定期报告 2021-03-22
2021-03-29 3960.38 未披露
更多>>
from December 31, 2019 to December 31, 2020 Shares issued under stock option and employee stock purchase plans Shares issued in connection with at the market agreement Shares issued in underwritten public offering
2020-12-31
2020-11-06 3956.73 未披露 定期报告 2020-11-05
2020-11-05 3956.71 未披露 定期报告 2020-10-31
2020-11-05 3956.25 未披露
更多>>
From June 30, 2020 to September 30, 2020 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
2020-09-30
2020-08-06 3912.64 未披露 定期报告 2020-07-31
2020-08-06 3909.39 未披露
更多>>
From March 31, 2020 to June 30, 2020 Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
2020-06-30
2020-06-18 3593.32 未披露
更多>>
1.Common stock offered by us pursuant to this prospectus supplement 13,377,926 shares 2.The number of shares of common stock to be outstanding after this offering is based on 22,555,303 shares of common stock outstanding as of June 12, 2020
2020-06-18
2020-06-15 2255.53 未披露 定期报告 2020-06-12
2020-06-12 2067.53 未披露 定期报告 2020-06-10
2020-05-06 1893.81 未披露 定期报告 2020-04-30
2020-04-28 1808.21 未披露 定期报告 2020-04-21
2020-04-28 1785.76 未披露 定期报告 2020-04-08
2020-05-06 1773.08 未披露
更多>>
From December 31, 2019 to March 31, 2020 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
2020-03-31
2020-03-26 1757.47 未披露 定期报告 2020-03-13
2020-03-26 1697.21 未披露
更多>>
From December 31, 2018 to December 31, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
2019-12-31
2019-12-06 1671.32 未披露 定期报告 2019-12-04
2019-11-12 1613.01 未披露 定期报告 2019-10-31
2019-11-12 1590.45 未披露
更多>>
from June 30, 2019 to September 30, 2019 Shares Issued in Connection with Cantor Agreement
2019-09-30
2019-08-07 1501.86 未披露 定期报告 2019-07-31
2019-08-07 1481.69 未披露
更多>>
from March 31, 2019 to June 30,2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
2019-06-30
2019-05-07 1376.89 未披露 定期报告 2019-04-30
2019-04-26 1353.46 未披露 定期报告 2019-04-22
2019-04-26 1295.07 未披露 定期报告 2019-04-09
2019-05-07 1284.47 未披露
更多>>
from December 31, 2018 to March 31, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
2019-03-31
2019-03-07 1243.97 未披露 定期报告 2019-02-28
2019-03-07 1195.76 未披露
更多>>
From December 31, 2017 to February 11, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with Kolltan Severance On February 8, 2019, Celldex Therapeutics, Inc. (the “Company”) filed a Certificate of Amendment to the Company’s Third Restated Certificate of Incorporation with the Secretary of State of the State of Delaware (the “Certificate of Amendment”), which effected, immediately upon filing, a one-for-fifteen reverse stock split (the “Reverse Stock Split”) of the Company’s issued and outstanding common stock, $0.001 par value per share (the “Common Stock”).As a result of the Reverse Stock Split, every fifteen shares of Common Stock issued and outstanding was converted into one share of Common Stock and the total number of shares of Common Stock outstanding will be reduced from approximately 181.8 million shares to approximately 12.1 million shares. No fractional shares were issued in connection with the Reverse Stock Split. Stockholders who would otherwise be entitled to a fractional share of Common Stock are instead entitled to receive a proportional cash payment.Trading of the Common Stock on a Reverse Stock Split-adjusted basis on the Nasdaq Capital Market will begin at the opening of trading on February 11, 2019
2019-02-11
2018-11-07 17246.56 未披露 定期报告 2018-10-31
2018-11-07 16857.55 未披露 定期报告 2018-09-30
2018-08-08 16244.23 未披露 定期报告 2018-07-31
2018-08-08 15664.59 未披露 定期报告 2018-06-30
2018-05-10 14339.28 未披露 定期报告 2018-05-03
2018-04-30 14338.73 未披露 定期报告 2018-04-10
2018-05-10 14336.88 未披露 定期报告 2018-03-31
2018-03-07 14107.37 未披露 定期报告 2018-02-28
2018-03-07 13852.04 未披露
更多>>
from December 31, 2016 to December 31, 2017 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with Kolltan Severance
2017-12-31
2017-11-07 13598.53 未披露 定期报告 2017-10-31
2017-11-07 13210.85 未披露 定期报告 2017-09-30
2017-08-08 12834.18 未披露 定期报告 2017-07-31
2017-08-08 12741.20 未披露 定期报告 2017-06-30
2017-04-28 12510.47 未披露 定期报告 2017-04-10
2017-05-09 12417.37 未披露 定期报告 2017-03-31
2017-03-14 12321.34 未披露 定期报告 2017-03-06
2017-01-26 12227.84 未披露 定期报告 2017-01-24
2017-03-14 12051.67 未披露
更多>>
from December 31, 2015 to December 31, 2016 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with the Kolltan Acquisition Shares Issued in Connection with Kolltan Severance
2016-12-31
2016-11-07 10124.88 未披露 定期报告 2016-09-30
2016-08-08 10054.55 未披露 定期报告 2016-07-31
2016-08-08 9939.45 未披露 定期报告 2016-06-30
2016-05-05 9871.85 未披露 定期报告 2016-04-26
2016-05-05 9871.85 未披露 定期报告 2016-03-31
2016-02-23 9870.35 未披露 定期报告 2016-02-16
2016-02-23 9868.56 未披露
更多>>
from December 31, 2014 to December 31, 2015 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Underwritten Offering
2015-12-31
2015-11-05 9864.57 未披露 定期报告 2015-09-30
2015-08-10 9859.54 未披露 定期报告 2015-07-28
2015-08-10 9854.83 未披露 定期报告 2015-06-30
2015-04-23 9848.08 未披露 定期报告 2015-04-22
2015-04-29 9848.06 未披露 定期报告 2015-03-31
2015-02-24 8960.86 未披露 定期报告 2015-02-17
2015-02-24 8959.28 未披露
更多>>
from December 31, 2013 to December 31, 2014 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Supply Agreement
2014-12-31
2014-11-05 8958.91 未披露 定期报告 2014-10-31
2014-11-05 8943.69 未披露 定期报告 2014-09-30
2014-08-07 8940.38 未披露 定期报告 2014-07-28
2014-08-07 8939.62 未披露 定期报告 2014-06-30
2014-05-01 8935.78 未披露 定期报告 2014-03-31
2014-03-03 8925.17 未披露 定期报告 2014-02-19
2014-03-03 8924.68 未披露
更多>>
from December 31, 2012 to December 31, 2013 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
2013-12-31
2013-11-08 8110.82 未披露 定期报告 2013-10-29
2013-11-08 8110.81 未披露 定期报告 2013-09-30
2013-08-06 8098.79 未披露 定期报告 2013-07-29
2013-08-06 8097.77 未披露 定期报告 2013-06-30
2013-05-03 8087.03 未披露 定期报告 2013-03-31
2013-03-08 8059.93 未披露 定期报告 2013-02-28
2013-03-08 6435.95 未披露
更多>>
from December 31, 2011 to December 31, 2012 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
2012-12-31
2012-11-02 6197.51 未披露 定期报告 2012-10-30
2012-11-02 6080.74 未披露 定期报告 2012-09-30
2012-08-09 5929.21 未披露 定期报告 2012-07-31
2012-08-09 5875.36 未披露 定期报告 2012-06-30
2012-05-04 5873.56 未披露 定期报告 2012-03-31
2012-03-08 5716.06 未披露 定期报告 2012-02-29
2012-03-08 4421.06 未披露
更多>>
from December 31, 2010 to December 31, 2011 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
2011-12-31
2011-08-04 4414.72 未披露 定期报告 2011-06-30
2011-05-05 3255.54 未披露 定期报告 2011-04-28
2011-03-09 3205.54 未披露
更多>>
from December 31, 2009 to December 31, 2010 Shares Issued under Stock Option and Employee Stock Purchase Plans
2010-12-31
2010-11-04 3205.19 未披露 定期报告 2010-09-30
2010-08-05 3188.69 未披露 定期报告 2010-06-30
2010-05-06 3177.97 未披露 定期报告 2010-05-03
2010-05-06 3175.97 未披露 定期报告 2010-03-31
2010-05-12 3171.11 未披露 定期报告 2010-02-25
2010-03-12 3168.51 未披露
更多>>
from December 31, 2008 to December 31, 2009 Shares Issued in Connection with the CuraGen Merger Shares Issued under Stock Option and Employee Stock Purchase Plans
2009-12-31
2009-03-02 1582.06 未披露 定期报告 2009-02-20
2009-03-02 2141.21 未披露
更多>>
from December 31, 2007 to December 31, 2008 Exchange of Class A for Common Stock Shares Issued to Medarex in Settlement of a Payable Shares Received in Exchange in the Merger Shares Issued to Pfizer in connection with the CDX-110 Licensing Agreement Shares Issued to Duke University in Settlement of a Payable Reflect the one-for-twelve reverse stock split effected on March 7, 2008
2008-12-31
2008-03-18 1492.70 未披露 定期报告 2008-03-13
2008-03-18 618.23 未披露
更多>>
from December 31, 2006 to March 10, 2008 Employee Stock Purchase Plan Issuances Reflect the one-for-twelve reverse stock split effected on March 7, 2008
2008-03-10
2007-03-16 7418.40 未披露 定期报告 2007-03-01
2007-03-16 7418.25 未披露
更多>>
from December 31, 2005 to December 31, 2006 Shares Issued upon Exercise of Stock Options Employee Stock Purchase Plan Issuances Reclassification of Deferred Compensation upon Adoption of FAS 123R
2006-12-31
2006-03-16 7417.27 未披露 定期报告 2006-03-01
2006-03-16 7416.68 未披露
更多>>
from December 31, 2004 to December 31, 2005 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuances Issuance of Restricted Stock Units Amortization of Deferred Compensation
2005-12-31
2005-03-16 7413.28 未披露 定期报告 2005-03-01
2005-03-16 7413.13 未披露
更多>>
from December 31, 2003 to December 31, 2004 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance
2004-12-31
2004-03-15 7395.91 未披露 定期报告 2004-03-01
2004-03-15 6470.81 未披露
更多>>
from December 31, 2002 to December 31, 2003 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance Issuance of Restricted Stock Units Amortization of Deferred Compensation
2003-12-31
2003-03-25 6046.87 未披露 定期报告 2003-03-14
2003-03-25 6033.23 未披露
更多>>
from December 31, 2001 to December 31, 2002 Employee Stock Purchase Plan Issuance Purchase of 132,600 Shares of Treasury Stock at Cost
2002-12-31
2002-03-29 6045.84 未披露 定期报告 2002-03-11
2002-03-29 6044.91 未披露
更多>>
from December 31, 2000 to December 31, 2001 Shares Issued upon Exercise of Stock Options Shares Issued upon Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance
2001-12-31
2001-03-27 5728.55 未披露 定期报告 2001-03-01
2001-03-27 5714.42 未披露
更多>>
from DECEMBER 31, 1999 to DECEMBER 31, 2000 Shares Issued upon Exercise of Stock Options Shares Issued upon Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance Shares Issued for Acquisition of Megan Health, Inc
2000-12-31
2000-03-28 5001.28 未披露 定期报告 2000-03-10
2000-03-28 4812.74 未披露
更多>>
from DECEMBER 31, 1998 to DECEMBER 31, 1999 Issuance at $0.10 to $1.81 per Share upon Exercise of Stock Options Employee Stock Purchase Plan Issuance at $1.46 to $1.78 per Share Net Proceeds from Stock Issuance
1999-12-31
1999-03-25 4253.21 未披露 定期报告 1999-03-01
1999-03-25 4250.86 未披露
更多>>
from December 31, 1997 to December 31, 1998 Issuance at $0.60 to $1.81 per Share upon Exercise of Stock Options Employee Stock Purchase Employee Stock Purchase $1.65 and $1.94 per Share Returned Shares from Settlement of Litigation at $2.50 per Share Net Proceeds from Stock Issuance Acquisition of Virus Research Institute, Inc.
1998-12-31
1998-03-30 2647.89 未披露 定期报告 1998-03-02
1998-03-30 2647.77 未披露
更多>>
from December 31, 1996 to December 31, 1997 Issuance at $1.81 to $2.13 per Share upon Exercise of Stock Options of Stock Options Settlement of Litigation Compensation Expense Associated with Issuance at $1.94 per with Issuance at $1.94 per Employee Stock Purchase Plan Issuance at $1.38 and $1.39 per Share
1997-12-31
1997-03-26 2494.66 未披露
更多>>
from December 31, 1995 to December 31, 1996 Issuance at $.60 to $3.56 per Share upon Exercise per Share upon Exercise Net Proceeds from Stock Issuance Employee Stock Purchase Plan Issuance at $2.71 per Share
1996-12-31
1996-04-01 1989.68 未披露 定期报告 1996-03-15
1996-04-01 1988.27 未披露
更多>>
from DECEMBER 31, 1994 to DECEMBER 31, 1995 Issuance at $.60 to $4.25 per Share upon Exercise of Stock Options Private Placement Proceeds Issuance at $1.65 upon Exercise of Stock Warrants Purchase of 16,466 Shares of Treasury Stock at Cost
1995-12-31
1996-04-01 1703.79 未披露
更多>>
from DECEMBER 31, 1993 to DECEMBER 31, 1994 Issuance at $2.13 to $5.25 per Share upon Exercise per Share upon Exercise Employee Stock Purchase Plan Issuance at $2.13 per Share
1994-12-31
From June 30, 2025 to September 30, 2025 Shares issued under stock option and employee stock purchase plans
From March 31, 2025 to June 30, 2025 Shares issued under stock option and employee stock purchase plans
From December 31, 2024 to March 31, 2025 Shares issued under stock option and employee stock purchase plans
From December 31, 2023 to December 31, 2024 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
From June 30, 2024 to September 30, 2024 Shares issued under stock option and employee stock purchase plans
From March 31, 2024 to June 30, 2024 Shares issued under stock option and employee stock purchase plans
From December 31, 2023 to March 31, 2024 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
Common stock offered 8,520,000 shares by the company
From December 31, 2022 to December 31, 2023 Shares issued in underwritten offering, net Shares issued under stock option and employee stock purchase plans
Common stock offered 7,425,000 shares by the company
From June 30, 2023 to September 30, 2023 Shares issued under stock option and employee stock purchase plans
From December 31, 2022 to March 31, 2023 Shares issued under stock option and employee stock purchase plans
From December 31, 2021 to December 31, 2022 Shares issued under stock option and employee stock purchase plans
From June 30, 2022 to September 30, 2022 Shares issued under stock option and employee stock purchase plans
From March 31, 2022 to June 30, 2022 Shares issued under stock option and employee stock purchase plans
From December 31, 2021 to March 31, 2022 Shares issued under stock option and employee stock purchase plans
From December 31, 2020 to December 31, 2021 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
From June 30, 2021 to September 30, 2021 Shares issued under stock option and employee stock purchase plans Shares issued in underwritten offering, net
1.Common stock offered 5,952,381 shares. 2.The number of shares of common stock to be outstanding after this offering is based on 39,614,638 shares of common stock outstanding as of March 31, 2021.
From March 31, 2021 to June 30, 2021 Shares issued under stock option and employee stock purchase plans
from December 31, 2020 to March 31, 2021 Shares issued under stock option and employee stock purchase plans
from December 31, 2019 to December 31, 2020 Shares issued under stock option and employee stock purchase plans Shares issued in connection with at the market agreement Shares issued in underwritten public offering
From June 30, 2020 to September 30, 2020 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
From March 31, 2020 to June 30, 2020 Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
1.Common stock offered by us pursuant to this prospectus supplement 13,377,926 shares 2.The number of shares of common stock to be outstanding after this offering is based on 22,555,303 shares of common stock outstanding as of June 12, 2020
From December 31, 2019 to March 31, 2020 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
From December 31, 2018 to December 31, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
from June 30, 2019 to September 30, 2019 Shares Issued in Connection with Cantor Agreement
from March 31, 2019 to June 30,2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
from December 31, 2018 to March 31, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement
From December 31, 2017 to February 11, 2019 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with Kolltan Severance On February 8, 2019, Celldex Therapeutics, Inc. (the “Company”) filed a Certificate of Amendment to the Company’s Third Restated Certificate of Incorporation with the Secretary of State of the State of Delaware (the “Certificate of Amendment”), which effected, immediately upon filing, a one-for-fifteen reverse stock split (the “Reverse Stock Split”) of the Company’s issued and outstanding common stock, $0.001 par value per share (the “Common Stock”).As a result of the Reverse Stock Split, every fifteen shares of Common Stock issued and outstanding was converted into one share of Common Stock and the total number of shares of Common Stock outstanding will be reduced from approximately 181.8 million shares to approximately 12.1 million shares. No fractional shares were issued in connection with the Reverse Stock Split. Stockholders who would otherwise be entitled to a fractional share of Common Stock are instead entitled to receive a proportional cash payment.Trading of the Common Stock on a Reverse Stock Split-adjusted basis on the Nasdaq Capital Market will begin at the opening of trading on February 11, 2019
from December 31, 2016 to December 31, 2017 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with Kolltan Severance
from December 31, 2015 to December 31, 2016 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Connection with the Kolltan Acquisition Shares Issued in Connection with Kolltan Severance
from December 31, 2014 to December 31, 2015 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Underwritten Offering
from December 31, 2013 to December 31, 2014 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Supply Agreement
from December 31, 2012 to December 31, 2013 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
from December 31, 2011 to December 31, 2012 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
from December 31, 2010 to December 31, 2011 Shares Issued under Stock Option and Employee Stock Purchase Plans Shares Issued in Connection with Cantor Agreement Shares Issued in Underwritten Offering
from December 31, 2009 to December 31, 2010 Shares Issued under Stock Option and Employee Stock Purchase Plans
from December 31, 2008 to December 31, 2009 Shares Issued in Connection with the CuraGen Merger Shares Issued under Stock Option and Employee Stock Purchase Plans
from December 31, 2007 to December 31, 2008 Exchange of Class A for Common Stock Shares Issued to Medarex in Settlement of a Payable Shares Received in Exchange in the Merger Shares Issued to Pfizer in connection with the CDX-110 Licensing Agreement Shares Issued to Duke University in Settlement of a Payable Reflect the one-for-twelve reverse stock split effected on March 7, 2008
from December 31, 2006 to March 10, 2008 Employee Stock Purchase Plan Issuances Reflect the one-for-twelve reverse stock split effected on March 7, 2008
from December 31, 2005 to December 31, 2006 Shares Issued upon Exercise of Stock Options Employee Stock Purchase Plan Issuances Reclassification of Deferred Compensation upon Adoption of FAS 123R
from December 31, 2004 to December 31, 2005 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuances Issuance of Restricted Stock Units Amortization of Deferred Compensation
from December 31, 2003 to December 31, 2004 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance
from December 31, 2002 to December 31, 2003 Shares Issued upon Exercise of Stock Options Shares Issued upon Cashless Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance Issuance of Restricted Stock Units Amortization of Deferred Compensation
from December 31, 2001 to December 31, 2002 Employee Stock Purchase Plan Issuance Purchase of 132,600 Shares of Treasury Stock at Cost
from December 31, 2000 to December 31, 2001 Shares Issued upon Exercise of Stock Options Shares Issued upon Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance
from DECEMBER 31, 1999 to DECEMBER 31, 2000 Shares Issued upon Exercise of Stock Options Shares Issued upon Exercise of Warrants Employee Stock Purchase Plan Issuance Net Proceeds from Stock Issuance Shares Issued for Acquisition of Megan Health, Inc
from DECEMBER 31, 1998 to DECEMBER 31, 1999 Issuance at $0.10 to $1.81 per Share upon Exercise of Stock Options Employee Stock Purchase Plan Issuance at $1.46 to $1.78 per Share Net Proceeds from Stock Issuance
from December 31, 1997 to December 31, 1998 Issuance at $0.60 to $1.81 per Share upon Exercise of Stock Options Employee Stock Purchase Employee Stock Purchase $1.65 and $1.94 per Share Returned Shares from Settlement of Litigation at $2.50 per Share Net Proceeds from Stock Issuance Acquisition of Virus Research Institute, Inc.
from December 31, 1996 to December 31, 1997 Issuance at $1.81 to $2.13 per Share upon Exercise of Stock Options of Stock Options Settlement of Litigation Compensation Expense Associated with Issuance at $1.94 per with Issuance at $1.94 per Employee Stock Purchase Plan Issuance at $1.38 and $1.39 per Share
from December 31, 1995 to December 31, 1996 Issuance at $.60 to $3.56 per Share upon Exercise per Share upon Exercise Net Proceeds from Stock Issuance Employee Stock Purchase Plan Issuance at $2.71 per Share
from DECEMBER 31, 1994 to DECEMBER 31, 1995 Issuance at $.60 to $4.25 per Share upon Exercise of Stock Options Private Placement Proceeds Issuance at $1.65 upon Exercise of Stock Warrants Purchase of 16,466 Shares of Treasury Stock at Cost
from DECEMBER 31, 1993 to DECEMBER 31, 1994 Issuance at $2.13 to $5.25 per Share upon Exercise per Share upon Exercise Employee Stock Purchase Plan Issuance at $2.13 per Share