主要股东
注：以下部分股东代表特定权益共同体，直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | 贝莱德集团公司 | 是 | 335.34万 | 11.64% | 新增 | 新增 | -- |
| 2 | 领航集团有限公司 | 是 | 323.21万 | 11.22% | 新增 | 新增 | -- |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 是 | 221.11万 | 7.68% | 新增 | 新增 | -- |
| 4 | Deerfield Partners, L.P. | 是 | 147.63万 | 5.13% | 新增 | 新增 | -- |
| 5 | Timothy Herbert | 否 | 32.14万 | 1.10% |
|
|
-- |
| 6 | Richard Buchholz | 否 | 7.18万 | -- |
|
|
-- |
| 7 | Shawn T McCormick | 否 | 5.16万 | -- |
|
|
-- |
| 8 | Casey Tansey | 否 | 5.12万 | -- |
|
|
-- |
| 9 | Dana G. Mead, Jr. | 否 | 5.00万 | -- |
|
|
-- |
| 10 | Bryan K. Phillips | 否 | 3.75万 | -- |
|
|
-- |
| 11 | Gary L. Ellis | 否 | 1.79万 | -- |
|
|
-- |
| 12 | Shelley Broader | 否 | 1.01万 | -- |
|
|
-- |
| 13 | Carlton W. Weatherby | 否 | 0.92万 | -- |
|
|
-- |
| 14 | Georgia Garinois Melenikiotou | 否 | 0.91万 | -- |
|
|
-- |
| 15 | Cynthia B. Burks | 否 | 0.45万 | -- |
|
|
-- |
| 16 | Myriam J. Curet | 否 | 0.29万 | -- |
|
|
-- |
| 17 | Randall A. Ban | 否 | 0.14万 | -- |
|
|
-- |
内部人交易
| 日期 | 股东名称 | 变动股数(万股) | 交易后持股数量(万股) | 交易价格 | 是否直接持有 | 内部人类型 |
|---|---|---|---|---|---|---|
| 2026-05-15 | Rondoni John |
|
2.72 | 43.28 | 是 | Chief Product and Innovation Officer |
| 2026-05-14 | Rondoni John |
|
2.98 | 43.01 | 是 | Chief Product and Innovation Officer |
| 2026-05-08 | mcCormick Shawn |
|
2.77 | 45.31 | 是 | -- |
| 2026-04-30 | Melenikiotou Georgia |
|
0.80 | 0.00 | 是 | -- |
| 2026-04-30 | mcCormick Shawn |
|
2.84 | 0.00 | 是 | -- |
| 2026-04-30 | Broader Shelley G |
|
0.85 | 0.00 | 是 | -- |
| 2026-04-30 | Burks Cynthia |
|
0.62 | 0.00 | 是 | -- |
| 2026-04-30 | Curet Myriam |
|
0.69 | 0.00 | 是 | -- |
| 2026-04-30 | Tansey Casey M |
|
2.63 | 0.00 | 是 | -- |
| 2026-04-30 | Ellis Gary Lee |
|
1.08 | 0.00 | 是 | -- |
| 2026-04-30 | Mead Dana G Jr. |
|
2.62 | 0.00 | 是 | -- |
| 2026-04-15 | Ellis Gary Lee |
|
0.73 | 52.07 | 是 | -- |
| 2026-04-15 | Broader Shelley G |
|
0.49 | 52.07 | 是 | -- |
| 2026-04-15 | Tansey Casey M |
|
2.27 | 52.07 | 是 | -- |
| 2026-04-15 | Melenikiotou Georgia |
|
0.45 | 52.07 | 是 | -- |
| 2026-02-20 | Rondoni John |
|
1.53 | 0.00 | 是 | Chief Product and Innovation Officer |
| 2026-02-20 | Rondoni John |
|
1.45 | 59.53 | 是 | Chief Product and Innovation Officer |
| 2026-02-20 | Rondoni John |
|
3.05 | 0.00 | 是 | Chief Product and Innovation Officer |
| 2026-02-20 | Weatherby Carlton |
|
0.88 | 0.00 | 是 | Chief Strategy and Growth Officer |
| 2026-02-20 | Weatherby Carlton |
|
0.81 | 59.53 | 是 | Chief Strategy and Growth Officer |
| 2026-02-20 | Weatherby Carlton |
|
2.91 | 0.00 | 是 | Chief Strategy and Growth Officer |
| 2026-02-20 | Weatherby Carlton |
|
4.17 | 0.00 | 是 | Chief Strategy and Growth Officer |
| 2026-02-20 | Mann Melissa |
|
2.36 | 0.00 | 是 | Chief People Officer |
| 2026-02-20 | Kelly Jason P |
|
1.99 | 0.00 | 是 | Chief Manufacturing and Quality Officer |
| 2026-02-20 | Phillips Bryan K |
|
1.49 | 0.00 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-20 | Phillips Bryan K |
|
1.42 | 59.53 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-20 | Phillips Bryan K |
|
3.01 | 0.00 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-20 | Phillips Bryan K |
|
3.85 | 0.00 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-20 | Herbert Timothy P. |
|
4.17 | 0.00 | 是 | CEO and President |
| 2026-02-20 | Herbert Timothy P. |
|
3.77 | 59.53 | 是 | CEO and President |
| 2026-02-20 | Herbert Timothy P. |
|
9.98 | 0.00 | 是 | CEO and President |
| 2026-02-13 | Phillips Bryan K |
|
1.25 | 59.76 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-13 | Weatherby Carlton |
|
0.66 | 59.76 | 是 | Chief Strategy and Growth Officer |
| 2026-02-13 | Kelly Jason P |
|
0.40 | 59.76 | 是 | Chief Manufacturing and Quality Officer |
| 2026-02-13 | Mann Melissa |
|
0.77 | 59.76 | 是 | Chief People Officer |
| 2026-02-13 | Rondoni John |
|
1.29 | 59.76 | 是 | Chief Product and Innovation Officer |
| 2026-02-13 | Herbert Timothy P. |
|
3.27 | 59.76 | 是 | CEO and President |
| 2026-02-13 | Buchholz Richard |
|
4.40 | 59.76 | 是 | Interim CFO |
| 2026-02-09 | Buchholz Richard |
|
4.46 | 66.33 | 是 | Interim CFO |
| 2026-02-09 | Rondoni John |
|
1.35 | 66.33 | 是 | Chief Product and Innovation Officer |
| 2026-02-09 | Herbert Timothy P. |
|
3.43 | 66.33 | 是 | CEO and President |
| 2026-02-09 | Phillips Bryan K |
|
1.31 | 66.33 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2026-02-09 | Weatherby Carlton |
|
0.71 | 66.33 | 是 | Chief Strategy and Growth Officer |
| 2026-01-15 | Ellis Gary Lee |
|
0.68 | 96.47 | 是 | -- |
| 2026-01-15 | Broader Shelley G |
|
0.46 | 96.47 | 是 | -- |
| 2026-01-15 | Tansey Casey M |
|
2.24 | 96.47 | 是 | -- |
| 2026-01-15 | Melenikiotou Georgia |
|
0.42 | 96.47 | 是 | -- |
| 2026-01-09 | Rondoni John |
|
1.38 | 100.00 | 是 | Chief Product and Innovation Officer |
| 2025-12-02 | mcCormick Shawn |
|
2.48 | 139.00 | 是 | -- |
| 2025-10-14 | Ellis Gary Lee |
|
0.65 | 78.84 | 是 | -- |
| 2025-10-14 | Broader Shelley G |
|
0.44 | 78.84 | 是 | -- |
| 2025-10-14 | Tansey Casey M |
|
2.22 | 78.84 | 是 | -- |
| 2025-10-14 | Melenikiotou Georgia |
|
0.40 | 78.84 | 是 | -- |
| 2025-08-29 | Buchholz Richard |
|
4.49 | 93.39 | 是 | Chief Financial Officer |
| 2025-08-19 | Buchholz Richard |
|
5.41 | 71.00 | 是 | Chief Financial Officer |
| 2025-08-19 | Buchholz Richard |
|
6.12 | 42.15 | 是 | Chief Financial Officer |
| 2025-08-19 | Buchholz Richard |
|
5.86 | 90.24 | 是 | Chief Financial Officer |
| 2025-08-19 | Buchholz Richard |
|
5.61 | 90.21 | 是 | Chief Financial Officer |
| 2025-08-19 | Buchholz Richard |
|
5.59 | 90.28 | 是 | Chief Financial Officer |
| 2025-07-15 | Melenikiotou Georgia |
|
0.38 | 128.00 | 是 | -- |
| 2025-07-15 | Broader Shelley G |
|
0.41 | 128.00 | 是 | -- |
| 2025-07-15 | Tansey Casey M |
|
2.20 | 128.00 | 是 | -- |
| 2025-07-15 | Ellis Gary Lee |
|
0.61 | 128.00 | 是 | -- |
| 2025-06-04 | mcCormick Shawn |
|
2.80 | 16.00 | 是 | -- |
| 2025-05-19 | Rondoni John |
|
1.38 | 149.38 | 是 | Chief Product and Innovation Officer |
| 2025-05-01 | Burks Cynthia |
|
0.27 | 0.00 | 是 | -- |
| 2025-05-01 | Mead Dana G Jr. |
|
2.27 | 0.00 | 是 | -- |
| 2025-05-01 | Tansey Casey M |
|
2.19 | 0.00 | 是 | -- |
| 2025-05-01 | Melenikiotou Georgia |
|
0.37 | 0.00 | 是 | -- |
| 2025-05-01 | mcCormick Shawn |
|
2.44 | 0.00 | 是 | -- |
| 2025-05-01 | mcCormick Shawn |
|
2.40 | 160.00 | 是 | -- |
| 2025-05-01 | Curet Myriam |
|
0.34 | 0.00 | 是 | -- |
| 2025-05-01 | Broader Shelley G |
|
0.40 | 0.00 | 是 | -- |
| 2025-05-01 | Ellis Gary Lee |
|
0.59 | 0.00 | 是 | -- |
| 2025-04-14 | Broader Shelley G |
|
0.27 | 149.70 | 是 | -- |
| 2025-04-14 | Ellis Gary Lee |
|
0.46 | 149.70 | 是 | -- |
| 2025-04-14 | Melenikiotou Georgia |
|
0.24 | 149.70 | 是 | -- |
| 2025-04-14 | Tansey Casey M |
|
2.06 | 149.70 | 是 | -- |
| 2025-03-03 | Ban Randy |
|
0.90 | 185.37 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-03-03 | Ban Randy |
|
0.77 | 186.20 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-03-03 | Ban Randy |
|
0.73 | 187.08 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-03-03 | Rondoni John |
|
1.55 | 185.60 | 是 | Chief Technology Officer |
| 2025-02-24 | Ban Randy |
|
1.34 | 0.00 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-24 | Ban Randy |
|
1.12 | 186.45 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-24 | Herbert Timothy P. |
|
4.34 | 0.00 | 是 | CEO and President |
| 2025-02-24 | Herbert Timothy P. |
|
3.51 | 186.45 | 是 | CEO and President |
| 2025-02-24 | Phillips Bryan K |
|
1.54 | 0.00 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2025-02-24 | Rondoni John |
|
1.78 | 186.45 | 是 | Chief Technology Officer |
| 2025-02-24 | Phillips Bryan K |
|
1.32 | 186.45 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2025-02-24 | Rondoni John |
|
1.88 | 0.00 | 是 | Chief Technology Officer |
| 2025-02-21 | Buchholz Richard |
|
3.22 | 0.00 | 是 | Chief Financial Officer |
| 2025-02-21 | Buchholz Richard |
|
3.83 | 0.00 | 是 | Chief Financial Officer |
| 2025-02-21 | Buchholz Richard |
|
3.61 | 186.45 | 是 | Chief Financial Officer |
| 2025-02-13 | Mann Melissa |
|
0.83 | 0.00 | 是 | Chief People Officer |
| 2025-02-13 | Rondoni John |
|
1.55 | 0.00 | 是 | Chief Technology Officer |
| 2025-02-13 | Kelly Jason P |
|
0.45 | 0.00 | 是 | Chief Manufacturing and Quality Officer |
| 2025-02-09 | Rondoni John |
|
1.04 | 170.49 | 是 | Chief Technology Officer |
| 2025-02-09 | Rondoni John |
|
1.10 | 182.15 | 是 | Chief Technology Officer |
| 2025-02-09 | Buchholz Richard |
|
2.76 | 182.15 | 是 | Chief Financial Officer |
| 2025-02-09 | Buchholz Richard |
|
3.27 | 0.00 | 是 | Chief Financial Officer |
| 2025-02-09 | Weatherby Carlton |
|
0.24 | 182.15 | 是 | Chief Strategy and Growth Officer |
| 2025-02-09 | Weatherby Carlton |
|
0.75 | 0.00 | 是 | Chief Strategy and Growth Officer |
| 2025-02-09 | Ban Randy |
|
0.28 | 182.15 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
0.78 | 0.00 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
3.28 | 67.63 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
3.03 | 178.54 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
2.93 | 179.41 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
2.80 | 180.79 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
2.42 | 181.90 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
2.10 | 182.90 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
1.85 | 183.79 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
1.50 | 184.81 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
1.12 | 185.84 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
0.78 | 186.96 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Ban Randy |
|
0.73 | 187.66 | 是 | Executive Vice President, Patient Access and Therapy Development |
| 2025-02-09 | Herbert Timothy P. |
|
0.89 | 182.15 | 是 | CEO and President |
| 2025-02-09 | Herbert Timothy P. |
|
2.50 | 0.00 | 是 | CEO and President |
| 2025-01-29 | Phillips Bryan K |
|
0.45 | 189.99 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2025-01-29 | Phillips Bryan K |
|
0.42 | 182.15 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2025-01-29 | Phillips Bryan K |
|
0.93 | 0.00 | 是 | Senior Vice President, General Counsel, Secretary and Chief Compliance Officer |
| 2025-01-15 | Ellis Gary Lee |
|
0.44 | 176.33 | 是 | -- |
| 2024-11-01 | Rondoni John |
|
1.72 | 71.00 | 是 | Chief Technology Officer |
| 2024-11-01 | Rondoni John |
|
2.01 | 42.15 | 是 | Chief Technology Officer |
| 2024-11-01 | Rondoni John |
|
1.43 | 192.93 | 是 | Chief Technology Officer |
| 2024-11-01 | Rondoni John |
|
1.27 | 193.92 | 是 | Chief Technology Officer |
| 2024-11-01 | Rondoni John |
|
1.17 | 194.84 | 是 | Chief Technology Officer |
| 2024-11-01 | Rondoni John |
|
1.13 | 196.42 | 是 | Chief Technology Officer |
| 2024-10-14 | Ellis Gary Lee |
|
0.43 | 210.46 | 是 | -- |
| 2024-09-09 | McCormick Shawn |
|
2.31 | 220.00 | 是 | -- |
| 2024-08-22 | Rondoni John |
|
1.64 | 71.00 | 是 | Chief Technology Officer |
| 2024-08-22 | Rondoni John |
|
1.52 | 189.16 | 是 | Chief Technology Officer |
| 2024-08-22 | Rondoni John |
|
1.14 | 190.04 | 是 | Chief Technology Officer |
| 2024-08-15 | Ban Randy |
|
0.31 | 194.91 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
0.79 | 42.15 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
0.70 | 187.10 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
0.40 | 188.66 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
0.31 | 189.64 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
1.92 | 42.15 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
1.84 | 189.06 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
1.68 | 190.20 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
1.47 | 191.92 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
1.35 | 192.60 | 是 | Chief Commercial Officer |
| 2024-08-15 | Ban Randy |
|
0.54 | 193.92 | 是 | Chief Commercial Officer |
| 2024-08-14 | McCormick Shawn |
|
2.39 | 0.94 | 是 | -- |
| 2024-07-31 | Mann Melissa |
|
0.32 | 0.00 | 是 | Chief People Officer |
| 2024-07-15 | Broader Shelley G. |
|
0.24 | 138.58 | 是 | -- |
| 2024-07-15 | Ellis Gary Lee |
|
0.42 | 138.58 | 是 | -- |
| 2024-07-15 | Tansey Casey M |
|
2.04 | 138.58 | 是 | -- |