股本结构
单位：万股
| 公告日期 | 2025-12-02 | 2025-11-21 | 2025-11-13 | 2025-11-13 | 2025-08-14 | 2025-08-14 |
|---|---|---|---|---|---|---|
| 证券总股本 | 8740.53 | 8731.34 | 8730.71 | 8652.78 | 8638.91 | 8632.21 |
| 普通股本 | 8740.53 | 8731.34 | 8730.71 | 8652.78 | 8638.91 | 8632.21 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-11-25 | 2025-11-15 | 2025-11-01 | 2025-09-30 | 2025-08-01 | 2025-06-30 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-12-02 | 8740.53 | 未披露 | 定期报告 | 2025-11-25 |
| 2025-11-21 | 8731.34 | 未披露 | 定期报告 | 2025-11-15 |
| 2025-11-13 | 8730.71 | 未披露 | 定期报告 | 2025-11-01 |
| 2025-11-13 | 8652.78 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Vesting of restricted stock units
Issuance of common stock upon the exercise of stock options and 2021 ESPP
|
2025-09-30 |
| 2025-08-14 | 8638.91 | 未披露 | 定期报告 | 2025-08-01 |
| 2025-08-14 | 8632.21 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Vesting of restricted stock units
|
2025-06-30 |
| 2025-04-22 | 8615.88 | 未披露 | 定期报告 | 2025-04-15 |
| 2025-05-15 | 8614.60 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock
Vesting of early exercise stock options
Vesting of restricted stock units
|
2025-03-31 |
| 2025-03-19 | 8604.50 | 未披露 | 定期报告 | 2025-02-28 |
| 2025-03-19 | 8583.64 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock
Vesting of early exercise stock options
Vesting of restricted stock units
Issuance of common stock in connection with the acquisition of Clade
Issuance of common stock via ATM, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock via PIPE, net of underwriting discounts and commissions and other issuance costs
|
2024-12-31 |
| 2024-11-05 | 8502.90 | 未披露 | 定期报告 | 2024-11-01 |
| 2024-11-05 | 8476.19 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of early exercise stock options
Vesting of restricted stock units
|
2024-09-30 |
| 2024-08-08 | 8471.60 | 未披露 | 定期报告 | 2024-08-01 |
| 2024-08-08 | 8455.18 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock upon the exercise of PIPE, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Issuance of common stock in connection with the transaction
Vesting of early exercise stock options
|
2024-06-30 |
| 2024-06-26 | 8450.08 | 未披露 | 定期报告 | 2024-06-13 |
| 2024-05-15 | 8317.67 | 未披露 | 定期报告 | 2024-05-07 |
| 2024-04-26 | 8284.74 | 未披露 | 定期报告 | 2024-04-24 |
| 2024-04-26 | 8240.43 | 未披露 | 定期报告 | 2024-04-19 |
| 2024-05-09 | 6480.96 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Vesting of restricted stock
Issuance of common stock upon the exercise of ATM, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock units
Vesting of early exercise stock options
|
2024-03-31 |
| 2024-03-14 | 6481.79 | 未披露 | 定期报告 | 2024-02-29 |
| 2024-03-14 | 6033.57 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Vesting of restricted stock
Vesting of early exercise stock options
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock units
|
2023-12-31 |
| 2023-11-09 | 5983.50 | 未披露 | 定期报告 | 2023-11-01 |
| 2023-11-09 | 5951.45 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of early exercise stock options
|
2023-09-30 |
| 2023-08-09 | 5976.53 | 未披露 | 定期报告 | 2023-08-01 |
| 2023-08-09 | 5930.90 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock upon the exercise of stock options
Vesting of early exercise stock options
|
2023-06-30 |
| 2023-04-28 | 5958.08 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-04-28 | 5957.01 | 未披露 | 定期报告 | 2023-04-15 |
| 2023-05-11 | 5910.68 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2023-03-31 |
| 2023-03-16 | 5917.06 | 未披露 | 定期报告 | 2023-02-28 |
| 2023-03-16 | 5847.37 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock upon the exercise of stock options
Vesting of early exercised stock options
Issuance of stock to collaboration partner
Vesting of restricted stock
|
2022-12-31 |
| 2022-11-10 | 5897.42 | 未披露 | 定期报告 | 2022-11-04 |
| 2022-11-10 | 5818.47 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2022-09-30 |
| 2022-08-11 | 5888.18 | 未披露 | 定期报告 | 2022-08-08 |
| 2022-08-11 | 5785.79 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2022-06-30 |
| 2022-05-16 | 5885.03 | 未披露 | 定期报告 | 2022-05-12 |
| 2022-04-21 | 5883.18 | 未披露 | 定期报告 | 2022-04-18 |
| 2022-04-21 | 5882.78 | 未披露 | 定期报告 | 2022-04-05 |
| 2022-05-16 | 5758.60 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of stock to collaboration partner
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2022-03-31 |
| 2022-03-17 | 5881.92 | 未披露 | 定期报告 | 2022-02-28 |
| 2022-03-17 | 5500.55 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of Series C preferred stock, net
Conversion of convertible preferred stock upon initial public offering
Issuance of common stock upon initial public offering, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2021-12-31 |
| 2021-11-10 | 5464.14 | 未披露 | 定期报告 | 2021-09-30 |
| 2021-08-12 | 5440.41 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock upon initial public offering, net of underwriting discounts and commissions and other issuance costs
Conversion of convertible preferred stock upon initial public offering
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
|
2021-06-30 |
| 2021-06-21 | 5482.46 | 未披露 | 定期报告 | 2021-06-18 |
| 2018-01-12 | 1.72 | 未披露 | 定期报告 | 2017-09-30 |
From June 30, 2025 to September 30, 2025
Vesting of restricted stock units
Issuance of common stock upon the exercise of stock options and 2021 ESPP
From March 31, 2025 to June 30, 2025
Vesting of restricted stock units
From December 31, 2024 to March 31, 2025
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock
Vesting of early exercise stock options
Vesting of restricted stock units
From December 31, 2023 to December 31, 2024
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock
Vesting of early exercise stock options
Vesting of restricted stock units
Issuance of common stock in connection with the acquisition of Clade
Issuance of common stock via ATM, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock via PIPE, net of underwriting discounts and commissions and other issuance costs
From June 30, 2024 to September 30, 2024
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of early exercise stock options
Vesting of restricted stock units
From March 31, 2024 to June 30, 2024
Issuance of common stock upon the exercise of PIPE, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Issuance of common stock in connection with the transaction
Vesting of early exercise stock options
From December 31, 2023 to March 31, 2024
Vesting of restricted stock
Issuance of common stock upon the exercise of ATM, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock units
Vesting of early exercise stock options
From December 31, 2022 to December 31, 2023
Vesting of restricted stock
Vesting of early exercise stock options
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of restricted stock units
From June 30, 2023 to September 30, 2023
Issuance of common stock upon the exercise of stock options and 2021 ESPP
Vesting of early exercise stock options
From March 31, 2023 to June 30, 2023
Issuance of common stock upon the exercise of stock options
Vesting of early exercise stock options
From December 31, 2022 to March 31, 2023
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
From December 31, 2021 to December 31, 2022
Issuance of common stock upon the exercise of stock options
Vesting of early exercised stock options
Issuance of stock to collaboration partner
Vesting of restricted stock
From June 30, 2022 to September 30, 2022
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
From March 31, 2022 to June 30, 2022
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
From December 31, 2021 to March 31, 2022
Issuance of stock to collaboration partner
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
From December 31, 2020 to December 31, 2021
Issuance of Series C preferred stock, net
Conversion of convertible preferred stock upon initial public offering
Issuance of common stock upon initial public offering, net of underwriting discounts and commissions and other issuance costs
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options
From March 31, 2021 to June 30, 2021
Issuance of common stock upon initial public offering, net of underwriting discounts and commissions and other issuance costs
Conversion of convertible preferred stock upon initial public offering
Issuance of common stock upon the exercise of stock options
Vesting of restricted stock
Vesting of early exercise stock options