主要股东
注：以下部分股东代表特定权益共同体，直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | Entities affiliated with Baker Bros. Advisors LP | 是 | 24.77万 | 9.99% |
|
|
-- |
| 2 | Mark S. Blumenkranz | 否 | 17.61万 | 7.62% |
|
|
-- |
| 3 | Entities affiliated with Lagunita | 是 | 16.97万 | 7.35% | 不变 | 不变 | -- |
内部人交易
| 日期 | 股东名称 | 变动股数(万股) | 交易后持股数量(万股) | 交易价格 | 是否直接持有 | 内部人类型 |
|---|---|---|---|---|---|---|
| 2025-10-23 | Iwicki Mark T |
|
10.35 | 0.81 | 是 | -- |
| 2025-10-22 | Brazzell Romulus K |
|
3.60 | 0.83 | 是 | Head of Research and Development and Chief Medical Officer |
| 2025-10-22 | Reumuth Mary |
|
2.99 | 0.83 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-10-22 | Reumuth Mary |
|
2.89 | 0.82 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-10-22 | Kharabi Darius |
|
4.18 | 0.83 | 是 | CHIEF BUSINESS OFFICER |
| 2025-10-22 | Bazemore Todd |
|
3.59 | 0.83 | 是 | -- |
| 2025-06-24 | Iwicki Mark T |
|
25.84 | 4.01 | 是 | -- |
| 2025-06-24 | Brazzell Romulus K |
|
8.27 | 4.01 | 是 | Head of Research and Development and Chief Medical Officer |
| 2025-06-24 | Bazemore Todd |
|
8.37 | 4.01 | 是 | Interim Chief Executive Officer, President and Chief Operating Officer |
| 2025-06-24 | Reumuth Mary |
|
6.21 | 4.01 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-06-24 | Kharabi Darius |
|
6.26 | 4.01 | 是 | CHIEF BUSINESS OFFICER |
| 2025-06-15 | KOVEN ANDREW I |
|
1.70 | 0.00 | 是 | -- |
| 2025-06-15 | Iwicki Mark T |
|
27.17 | 0.00 | 是 | -- |
| 2025-06-15 | PERRY GREGORY D |
|
1.33 | 0.00 | 是 | -- |
| 2025-06-15 | Rosen Howard B |
|
1.62 | 0.00 | 是 | -- |
| 2025-06-15 | Myers C. Daniel |
|
1.04 | 0.00 | 是 | -- |
| 2025-06-15 | Farid Marjan |
|
1.02 | 0.00 | 是 | -- |
| 2025-06-03 | Iwicki Mark T |
|
26.92 | 3.74 | 是 | -- |
| 2025-06-03 | Reumuth Mary |
|
6.57 | 3.74 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-06-03 | Brazzell Romulus K |
|
8.79 | 3.74 | 是 | Head of Research and Development and Chief Medical Officer |
| 2025-06-03 | Bazemore Todd |
|
8.78 | 3.74 | 是 | Interim Chief Executive Officer, President and Chief Operating Officer |
| 2025-06-03 | Kharabi Darius |
|
6.71 | 3.74 | 是 | CHIEF BUSINESS OFFICER |
| 2025-01-06 | Iwicki Mark T |
|
28.59 | 0.00 | 是 | CHIEF EXECUTIVE OFFICER |
| 2025-01-06 | Iwicki Mark T |
|
28.01 | 7.63 | 是 | CHIEF EXECUTIVE OFFICER |
| 2025-01-06 | Brazzell Romulus K |
|
9.49 | 0.00 | 是 | Head of Research and Development and Chief Medical Officer |
| 2025-01-06 | Brazzell Romulus K |
|
9.16 | 7.63 | 是 | Head of Research and Development and Chief Medical Officer |
| 2025-01-06 | Bazemore Todd |
|
9.31 | 0.00 | 是 | President and Chief Operating Officer |
| 2025-01-06 | Bazemore Todd |
|
9.11 | 7.63 | 是 | President and Chief Operating Officer |
| 2025-01-06 | Reumuth Mary |
|
7.03 | 0.00 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-01-06 | Reumuth Mary |
|
6.86 | 7.63 | 是 | CHIEF FINANCIAL OFFICER |
| 2025-01-06 | Kharabi Darius |
|
6.98 | 0.00 | 是 | CHIEF BUSINESS OFFICER |
| 2025-01-06 | Kharabi Darius |
|
6.78 | 7.63 | 是 | CHIEF BUSINESS OFFICER |
| 2024-06-26 | Brazzell Romulus K |
|
8.40 | 4.75 | 是 | Head of Research and Development and Chief Medical Officer |
| 2024-06-26 | Iwicki Mark T |
|
26.38 | 4.75 | 是 | CHIEF EXECUTIVE OFFICER |
| 2024-06-26 | Bazemore Todd |
|
8.30 | 4.75 | 是 | President and Chief Operating Officer |
| 2024-06-26 | Reumuth Mary |
|
6.02 | 4.75 | 是 | CHIEF FINANCIAL OFFICER |
| 2024-06-26 | Kharabi Darius |
|
5.97 | 4.75 | 是 | CHIEF BUSINESS OFFICER |
| 2024-06-11 | Blumenkranz Mark S. |
|
1.31 | 0.00 | 是 | -- |
| 2024-06-11 | KOVEN ANDREW I |
|
1.39 | 0.00 | 是 | -- |
| 2024-06-11 | PERRY GREGORY D |
|
1.09 | 0.00 | 是 | -- |
| 2024-06-11 | Rosen Howard B |
|
1.39 | 0.00 | 是 | -- |
| 2024-06-11 | Myers C. Daniel |
|
0.79 | 0.00 | 是 | -- |
| 2024-06-11 | Farid Marjan |
|
0.78 | 0.00 | 是 | -- |
| 2024-05-31 | Iwicki Mark T |
|
27.89 | 6.09 | 是 | CHIEF EXECUTIVE OFFICER |
| 2024-05-31 | Brazzell Romulus K |
|
8.95 | 6.09 | 是 | Head of Research and Development and Chief Medical Officer |
| 2024-05-31 | Bazemore Todd |
|
8.77 | 6.09 | 是 | President and Chief Operating Officer |
| 2024-05-31 | Reumuth Mary |
|
6.44 | 6.09 | 是 | CHIEF FINANCIAL OFFICER |
| 2024-05-31 | Kharabi Darius |
|
6.49 | 6.09 | 是 | CHIEF BUSINESS OFFICER |
| 2024-01-04 | Trachtenberg Eric |
|
6.93 | 0.00 | 是 | Chief Legal Officer, Chief Compliance Officer and Secretary |
| 2024-01-04 | Trachtenberg Eric |
|
6.81 | 6.74 | 是 | Chief Legal Officer, Chief Compliance Officer and Secretary |
| 2024-01-04 | Kharabi Darius |
|
6.51 | 6.73 | 是 | CHIEF BUSINESS OFFICER |
| 2024-01-04 | Kharabi Darius |
|
6.65 | 0.00 | 是 | CHIEF BUSINESS OFFICER |
| 2024-01-04 | Iwicki Mark T |
|
29.09 | 0.00 | 是 | CHIEF EXECUTIVE OFFICER |
| 2024-01-04 | Brazzell Romulus K |
|
9.15 | 6.74 | 是 | Head of Research and Development and Chief Medical Officer |
| 2024-01-04 | Reumuth Mary |
|
6.74 | 0.00 | 是 | CHIEF FINANCIAL OFFICER |
| 2024-01-04 | Reumuth Mary |
|
6.61 | 6.74 | 是 | CHIEF FINANCIAL OFFICER |
| 2024-01-04 | Iwicki Mark T |
|
28.63 | 6.73 | 是 | CHIEF EXECUTIVE OFFICER |
| 2024-01-04 | Brazzell Romulus K |
|
9.31 | 0.00 | 是 | Head of Research and Development and Chief Medical Officer |
| 2024-01-04 | Bazemore Todd |
|
9.12 | 0.00 | 是 | President and Chief Operating Officer |
| 2024-01-04 | Bazemore Todd |
|
8.98 | 6.74 | 是 | President and Chief Operating Officer |