Karyopharm
KPTI

股本结构

单位：万股
公告日期 2025-11-03 2025-10-14 2025-11-03 2025-08-11 2025-08-11 2025-05-12
证券总股本 1705.09 1592.69 870.20 867.13 864.70 863.99
普通股本 1705.09 1592.69 870.20 867.13 864.70 863.99
优先股 未披露 未披露 未披露 未披露 未披露 未披露
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2025-10-30 2025-10-14 2025-09-30 2025-08-06 2025-06-30 2025-05-07
注释：中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本（万股） 变动后优先股（万股） 变动原因 变动日期
2025-11-03 1705.09 未披露 定期报告 2025-10-30
2025-10-14 1592.69 未披露 定期报告 2025-10-14
2025-11-03 870.20 未披露
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From June 30, 2025 to September 30, 2025 Vesting of restricted stock
2025-09-30
2025-08-11 867.13 未披露 定期报告 2025-08-06
2025-08-11 864.70 未披露
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From March 31, 2025 to June 30, 2025 Shares issued under the employee stock purchase plan Vesting of restricted stock
2025-06-30
2025-05-12 863.99 未披露 定期报告 2025-05-07
2025-04-14 857.02 未披露 定期报告 2025-04-10
2025-04-14 856.96 未披露 定期报告 2025-04-02
2025-05-12 856.80 未披露
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From December 31, 2024 to March 31, 2025 Vesting of restricted stock
2025-03-31
2025-02-24 840.00 未披露
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A 1-for-15 reverse stock split of common stock.
2025-02-26
2025-02-24 12620.00 未披露 定期报告 2025-02-24
2025-02-19 12624.01 未披露 定期报告 2025-02-14
2025-02-19 12620.10 未披露
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From December 31, 2023 to December 31, 2024 Issuance of common stock for financial advisory fee Shares issued under the employee stock purchase plan Vesting of restricted stock
2024-12-31
2024-12-16 12619.07 未披露 定期报告 2024-12-04
2024-12-16 12614.91 未披露 定期报告 2024-11-30
2024-11-05 12531.45 未披露 定期报告 2024-10-31
2024-11-05 12530.30 未披露
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From June 30, 2024 to September 30, 2024 Vesting of restricted stock
2024-09-30
2024-08-06 12468.37 未披露 定期报告 2024-07-31
2024-08-06 12463.50 未披露
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From March 31, 2024 to June 30, 2024 Shares issued under the employee stock purchase plan Issuance of common stock for financial advisory fee Vesting of restricted stock
2024-06-30
2024-05-30 12461.57 未披露 定期报告 2024-05-28
2024-05-08 11771.03 未披露 定期报告 2024-05-03
2024-04-19 11646.57 未披露 定期报告 2024-04-04
2024-05-08 11645.70 未披露
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From December 31, 2023 to March 31, 2024 Vesting of restricted stock
2024-03-31
2024-04-19 11643.42 未披露 定期报告 2024-03-29
2024-02-29 11506.71 未披露 定期报告 2024-02-23
2024-02-29 11491.50 未披露
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From December 31, 2022 to December 31, 2023 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
2023-12-31
2023-11-02 11453.40 未披露 定期报告 2023-10-27
2023-11-02 11452.30 未披露
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From June 30, 2023 to September 30, 2023 Vesting of restricted stock
2023-09-30
2023-08-02 11435.45 未披露 定期报告 2023-07-28
2023-08-02 11434.00 未披露
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From March 31, 2023 to June 30, 2023 Exercise of stock options and shares issued under the employee stock purchase plan Vesting of restricted stock
2023-06-30
2023-05-04 11401.04 未披露 定期报告 2023-04-28
2023-05-04 11397.10 未披露
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From December 31, 2022 to March 31, 2023 Vesting of restricted stock
2023-03-31
2023-04-11 11395.61 未披露 定期报告 2023-03-29
2023-02-17 11334.21 未披露 定期报告 2023-02-10
2023-02-17 11321.30 未披露
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From December 31, 2021 to December 31, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
2022-12-31
2022-12-23 11321.32 未披露 定期报告 2022-12-15
2022-11-03 8115.50 未披露 定期报告 2022-10-28
2022-11-03 8102.70 未披露
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From June 30, 2022 to September 30, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
2022-09-30
2022-08-04 7980.66 未披露 定期报告 2022-07-29
2022-08-04 7979.80 未披露
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From March 31, 2022 to June 30, 2022 Exercise of stock options and shares issued under the employee stock purchase plan Vesting of restricted stock
2022-06-30
2022-05-05 7941.83 未披露 定期报告 2022-04-29
2022-05-05 7941.90 未披露
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From December 31, 2021 to March 31, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
2022-03-31
2022-04-08 7941.74 未披露 定期报告 2022-03-25
2022-03-01 7916.00 未披露 定期报告 2022-02-22
2022-03-01 7574.60 未披露
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From December 31, 2020 to December 31, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock for asset purchase Issuance of common stock, net of issuance costs
2021-12-31
2021-11-03 7554.75 未披露 定期报告 2021-10-27
2021-11-03 7550.20 未披露
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From June 30, 2021 to September 30, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock for asset purchase
2021-09-30
2021-08-05 7549.73 未披露 定期报告 2021-07-28
2021-08-05 7533.40 未披露
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From March 31, 2021 to June 30, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
2021-06-30
2021-05-04 7509.26 未披露 定期报告 2021-04-29
2021-05-04 7506.20 未披露
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From December 31,2020 to March 31, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
2021-03-31
2021-04-07 7506.15 未披露 定期报告 2021-03-26
2021-02-24 7463.43 未披露 定期报告 2021-02-16
2021-02-24 7392.30 未披露
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From December 31,2019 to December 31,2020 Vesting of restricted stock Issuance of common stock, net of issuance costs Exercise of stock options and shares issued under the employee stock purchase plan
2020-12-31
2020-11-02 7360.08 未披露 定期报告 2020-10-28
2020-11-02 7352.80 未披露
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From June 30, 2020 to September 30, 2020 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
2020-09-30
2020-08-04 7347.82 未披露 定期报告 2020-07-30
2020-08-04 7336.60 未披露
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From March 31, 2020 to June 30, 2020 Exercise of stock options and shares issued under the employee stock purchase plan
2020-06-30
2020-05-05 7312.19 未披露 定期报告 2020-04-30
2020-05-05 7309.50 未披露
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From December 31, 2019 to March 31, 2020 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
2020-03-31
2020-04-09 7308.95 未披露 定期报告 2020-03-27
2020-03-06 7162.04 未披露
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1.Common stock offered by us 6,250,000 shares 2.The number of shares of our common stock to be outstanding after this offering is based on 65,370,448 shares of our common stock issued and outstanding as of December 31, 2019
2020-03-06
2020-02-26 6554.81 未披露 定期报告 2020-02-14
2020-02-26 6537.04 未披露
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from December 31, 2018 to December 31, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1.0 million
2019-12-31
2019-11-04 6279.00 未披露 定期报告 2019-10-29
2019-11-04 6270.55 未披露
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from June 30, 2019 to September 30, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
2019-09-30
2019-08-07 6192.05 未披露 定期报告 2019-07-31
2019-08-07 6096.55 未披露
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from March 31, 2019 to June 30,2019 Exercise of stock options and shares issued under the employee stock purchase plan
2019-06-30
2019-05-09 6086.44 未披露
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from December 31, 2018 to March 31, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
2019-03-31
2019-05-10 6086.44 未披露 定期报告 2019-02-26
2019-02-28 6085.61 未披露 定期报告 2019-02-15
2019-02-28 6082.93 未披露
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from December 31, 2017 to December 31, 2018 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $231
2018-12-31
2018-11-08 6070.79 未披露 定期报告 2018-11-02
2018-11-08 6066.49 未披露 定期报告 2018-09-30
2018-08-07 6056.34 未披露 定期报告 2018-08-02
2018-08-07 6050.13 未披露 定期报告 2018-06-30
2018-07-02 6048.58 未披露 定期报告 2018-06-15
2018-05-10 4985.00 未披露 定期报告 2018-05-04
2018-04-27 4969.13 未披露 定期报告 2018-04-23
2018-05-10 4967.03 未披露 定期报告 2018-03-31
2018-03-15 4965.28 未披露 定期报告 2018-03-09
2018-03-15 4953.32 未披露
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from December 31, 2016 to December 31, 2017 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1,060
2017-12-31
2017-11-02 4718.08 未披露 定期报告 2017-10-30
2017-11-02 4715.42 未披露 定期报告 2017-09-30
2017-08-08 4713.89 未披露 定期报告 2017-07-31
2017-08-08 4712.32 未披露 定期报告 2017-06-30
2017-05-04 4711.82 未披露 定期报告 2017-04-28
2017-04-28 4198.27 未披露 定期报告 2017-04-18
2017-05-04 4190.23 未披露 定期报告 2017-03-31
2017-03-16 4190.12 未披露 定期报告 2017-03-10
2017-03-16 4188.78 未披露
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From December 31, 2015 to December 31, 2016 Vesting of restricted stock Settlements of restricted stock units for tax withholding obligations Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1,530
2016-12-31
2016-11-07 4124.34 未披露 定期报告 2016-11-02
2016-11-07 3972.40 未披露 定期报告 2016-09-30
2016-08-04 3598.93 未披露 定期报告 2016-06-30
2016-05-09 3596.04 未披露 定期报告 2016-05-03
2016-04-29 3592.89 未披露 定期报告 2016-04-19
2016-05-09 3592.47 未披露 定期报告 2016-03-31
2016-03-15 3588.12 未披露 定期报告 2016-03-07
2016-03-15 3586.48 未披露
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From December 31, 2014 to December 31, 2015 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock upon public offering, net of issuance costs of $6,520 Issuance of common stock, net of issuance costs of $284
2015-12-31
2015-11-09 3573.22 未披露 定期报告 2015-11-04
2015-11-09 3571.20 未披露 定期报告 2015-09-30
2015-08-10 3571.12 未披露 定期报告 2015-07-31
2015-08-10 3570.34 未披露 定期报告 2015-06-30
2015-05-11 3569.48 未披露 定期报告 2015-04-30
2015-05-11 3568.72 未披露 定期报告 2015-03-31
2015-03-13 3568.28 未披露 定期报告 2015-03-11
2015-03-13 3269.94 未披露
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from December 31,2013 to December 31,2014 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock upon public offering, net of issuance costs of $794
2014-12-31
2014-11-10 3270.06 未披露 定期报告 2014-11-04
2014-11-10 3261.44 未披露 定期报告 2014-09-30
2014-08-07 3267.01 未披露 定期报告 2014-07-31
2014-08-07 2972.04 未披露 定期报告 2014-06-30
2014-06-25 2978.64 未披露 定期报告 2014-05-31
2014-04-28 2976.25 未披露 定期报告 2014-04-16
2014-05-08 2961.89 未披露 定期报告 2014-03-31
2014-03-21 2975.37 未披露 定期报告 2014-03-14
2014-03-21 2958.73 未披露
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from December 31,2012 to December 31,2013 Issuance of Series A preferred stock Conversion of convertible preferred stock into common stock Issuance of shares related to preferred stock subscription Issuance of Series B preferred stock, net of issuance costs of $143 Issuance of Series B-1 preferred stock, net of issuance costs of $123 Proceeds from the sale of Series A-3 convertible preferred stock Proceeds from the sale of Series B convertible preferred stock Settlement of special participation preferred shares Exercise of stock options Vesting of restricted stock Initial Public Offering, net of issance costs of $3,207
2013-12-31
2013-12-20 2974.96 未披露 定期报告 2013-12-16
2013-11-07 2872.96 未披露
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gives effect to the 1-for-3.3 reverse stock split of our common stock that was effected on October 25, 2013.
2013-11-06
2013-10-28 2192.96 未披露
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The company gives effect to the 1-for-3.3 reverse stock split of our common stock that was effected on October 25, 2013.
2013-10-28
2013-12-20 259.13 6153.86 定期报告 2013-09-30
2013-10-04 808.67 3154.75
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from December 31, 2012 to June 30, 2013 Issuance of Series A convertible preferred stock Issuance of Series B convertible preferred stock, net of issuance costs of $143 Vesting of restricted stock Exercise of stock options
2013-06-30
From June 30, 2025 to September 30, 2025 Vesting of restricted stock
From March 31, 2025 to June 30, 2025 Shares issued under the employee stock purchase plan Vesting of restricted stock
From December 31, 2024 to March 31, 2025 Vesting of restricted stock
A 1-for-15 reverse stock split of common stock.
From December 31, 2023 to December 31, 2024 Issuance of common stock for financial advisory fee Shares issued under the employee stock purchase plan Vesting of restricted stock
From June 30, 2024 to September 30, 2024 Vesting of restricted stock
From March 31, 2024 to June 30, 2024 Shares issued under the employee stock purchase plan Issuance of common stock for financial advisory fee Vesting of restricted stock
From December 31, 2023 to March 31, 2024 Vesting of restricted stock
From December 31, 2022 to December 31, 2023 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
From June 30, 2023 to September 30, 2023 Vesting of restricted stock
From March 31, 2023 to June 30, 2023 Exercise of stock options and shares issued under the employee stock purchase plan Vesting of restricted stock
From December 31, 2022 to March 31, 2023 Vesting of restricted stock
From December 31, 2021 to December 31, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
From June 30, 2022 to September 30, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
From March 31, 2022 to June 30, 2022 Exercise of stock options and shares issued under the employee stock purchase plan Vesting of restricted stock
From December 31, 2021 to March 31, 2022 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
From December 31, 2020 to December 31, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock for asset purchase Issuance of common stock, net of issuance costs
From June 30, 2021 to September 30, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock for asset purchase
From March 31, 2021 to June 30, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
From December 31,2020 to March 31, 2021 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
From December 31,2019 to December 31,2020 Vesting of restricted stock Issuance of common stock, net of issuance costs Exercise of stock options and shares issued under the employee stock purchase plan
From June 30, 2020 to September 30, 2020 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
From March 31, 2020 to June 30, 2020 Exercise of stock options and shares issued under the employee stock purchase plan
From December 31, 2019 to March 31, 2020 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs
1.Common stock offered by us 6,250,000 shares 2.The number of shares of our common stock to be outstanding after this offering is based on 65,370,448 shares of our common stock issued and outstanding as of December 31, 2019
from December 31, 2018 to December 31, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1.0 million
from June 30, 2019 to September 30, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
from March 31, 2019 to June 30,2019 Exercise of stock options and shares issued under the employee stock purchase plan
from December 31, 2018 to March 31, 2019 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan
from December 31, 2017 to December 31, 2018 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $231
from December 31, 2016 to December 31, 2017 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1,060
From December 31, 2015 to December 31, 2016 Vesting of restricted stock Settlements of restricted stock units for tax withholding obligations Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock, net of issuance costs of $1,530
From December 31, 2014 to December 31, 2015 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock upon public offering, net of issuance costs of $6,520 Issuance of common stock, net of issuance costs of $284
from December 31,2013 to December 31,2014 Vesting of restricted stock Exercise of stock options and shares issued under the employee stock purchase plan Issuance of common stock upon public offering, net of issuance costs of $794
from December 31,2012 to December 31,2013 Issuance of Series A preferred stock Conversion of convertible preferred stock into common stock Issuance of shares related to preferred stock subscription Issuance of Series B preferred stock, net of issuance costs of $143 Issuance of Series B-1 preferred stock, net of issuance costs of $123 Proceeds from the sale of Series A-3 convertible preferred stock Proceeds from the sale of Series B convertible preferred stock Settlement of special participation preferred shares Exercise of stock options Vesting of restricted stock Initial Public Offering, net of issance costs of $3,207
gives effect to the 1-for-3.3 reverse stock split of our common stock that was effected on October 25, 2013.
The company gives effect to the 1-for-3.3 reverse stock split of our common stock that was effected on October 25, 2013.
from December 31, 2012 to June 30, 2013 Issuance of Series A convertible preferred stock Issuance of Series B convertible preferred stock, net of issuance costs of $143 Vesting of restricted stock Exercise of stock options
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