股本结构
单位：万股
| 公告日期 | 2025-11-07 | 2025-11-07 | 2025-08-08 | 2025-08-08 | 2025-05-09 | 2025-05-09 |
|---|---|---|---|---|---|---|
| 证券总股本 | 1968.17 | 1965.60 | 1959.66 | 1941.10 | 1929.42 | 1927.60 |
| 普通股本 | 1968.17 | 1965.60 | 1959.66 | 1941.10 | 1929.42 | 1927.60 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-11-04 | 2025-09-30 | 2025-08-05 | 2025-06-30 | 2025-05-06 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-11-07 | 1968.17 | 未披露 | 定期报告 | 2025-11-04 |
| 2025-11-07 | 1965.60 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Share repurchase in connection to the 2030 Notes
|
2025-09-30 |
| 2025-08-08 | 1959.66 | 未披露 | 定期报告 | 2025-08-05 |
| 2025-08-08 | 1941.10 | 未披露 |
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From March 31, 2025 to June 30, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2025-06-30 |
| 2025-05-09 | 1929.42 | 未披露 | 定期报告 | 2025-05-06 |
| 2025-04-22 | 1928.10 | 未披露 | 定期报告 | 2025-04-17 |
| 2025-05-09 | 1927.60 | 未披露 |
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From December 31, 2024 to March 31, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2025-03-31 |
| 2025-02-28 | 1925.54 | 未披露 | 定期报告 | 2025-02-25 |
| 2025-02-28 | 1910.60 | 未披露 |
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From December 31, 2023 to December 31, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Issuance of common stock, net of commissions and fees
|
2024-12-31 |
| 2024-11-08 | 1889.54 | 未披露 | 定期报告 | 2024-11-05 |
| 2024-11-08 | 1876.00 | 未披露 |
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From June 30, 2024 to September 30, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Issuance of common stock under ATM, net of commissions and fees
|
2024-09-30 |
| 2024-08-07 | 1826.90 | 未披露 | 定期报告 | 2024-08-05 |
| 2024-08-07 | 1810.30 | 未披露 |
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From March 31, 2024 to June 30, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2024-06-30 |
| 2024-05-08 | 1796.37 | 未披露 | 定期报告 | 2024-05-06 |
| 2024-04-25 | 1795.84 | 未披露 | 定期报告 | 2024-04-19 |
| 2024-05-08 | 1792.40 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2024-03-31 |
| 2024-04-25 | 1792.38 | 未披露 | 定期报告 | 2024-03-28 |
| 2024-02-29 | 1770.53 | 未披露 | 定期报告 | 2024-02-26 |
| 2024-02-29 | 1755.60 | 未披露 |
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From December 31, 2022 to December 31, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2023-12-31 |
| 2023-11-09 | 1743.60 | 未披露 | 定期报告 | 2023-11-06 |
| 2023-11-09 | 1742.10 | 未披露 |
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From June 30, 2023 to September 30, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2023-09-30 |
| 2023-08-09 | 1735.53 | 未披露 | 定期报告 | 2023-08-04 |
| 2023-08-09 | 1735.20 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2023-06-30 |
| 2023-05-08 | 1727.25 | 未披露 | 定期报告 | 2023-05-04 |
| 2023-04-20 | 1717.56 | 未披露 | 定期报告 | 2023-04-17 |
| 2023-05-08 | 1713.40 | 未披露 |
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From December 31, 2022 to March 31, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2023-03-31 |
| 2023-02-28 | 1707.67 | 未披露 | 定期报告 | 2023-02-22 |
| 2023-02-28 | 1695.10 | 未披露 |
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From December 31, 2021 to December 31, 2022
Issuance of common stock under employee stock compensation plans, net
|
2022-12-31 |
| 2022-11-08 | 1689.36 | 未披露 | 定期报告 | 2022-11-04 |
| 2022-11-08 | 1689.40 | 未披露 |
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From June 30, 2022 to September 30, 2022
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2022-09-30 |
| 2022-08-09 | 1688.28 | 未披露 | 定期报告 | 2022-08-05 |
| 2022-08-09 | 1688.20 | 未披露 |
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From March 31, 2022 to June 30, 2022
Issuance of common stock under employee stock compensation plans, net
|
2022-06-30 |
| 2022-04-22 | 1686.13 | 未披露 | 定期报告 | 2022-04-11 |
| 2022-05-09 | 1686.10 | 未披露 |
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From December 31, 2021 to March 31, 2022
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
|
2022-03-31 |
| 2022-02-28 | 1685.27 | 未披露 | 定期报告 | 2022-02-23 |
| 2022-02-28 | 1676.70 | 未披露 |
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From December 31, 2020 to December 31, 2021
Issuance of common stock under employee stock compensation plans, net
|
2021-12-31 |
| 2021-11-09 | 1671.16 | 未披露 | 定期报告 | 2021-11-05 |
| 2021-11-09 | 1670.70 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock under employee stock compensation plans, net
|
2021-09-30 |
| 2021-08-03 | 1667.65 | 未披露 | 定期报告 | 2021-07-30 |
| 2021-08-03 | 1667.60 | 未披露 |
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From March 31, 2021 to June 30, 2021
Issuance of common stock under employee stock compensation plans, net
|
2021-06-30 |
| 2021-04-23 | 1665.21 | 未披露 | 定期报告 | 2021-04-13 |
| 2021-05-06 | 1665.20 | 未披露 |
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From January 1, 2021 To March 31, 2021
Issuance of common stock under employee stock compensation plans, net
|
2021-03-31 |
| 2021-02-24 | 1661.24 | 未披露 | 定期报告 | 2021-02-18 |
| 2021-02-24 | 1608.00 | 未披露 |
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From December 31, 2019 to December 31, 2020
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2020-12-31 |
| 2020-11-12 | 1608.13 | 未披露 | 定期报告 | 2020-11-05 |
| 2020-11-06 | 1609.13 | 未披露 | 定期报告 | 2020-11-03 |
| 2020-11-12 | 1609.08 | 未披露 | 定期报告 | 2020-10-05 |
| 2020-11-06 | 1609.10 | 未披露 |
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From June 30, 2020 to September 30, 2020
Issuance of common stock under employee stock compensation plans,net
|
2020-09-30 |
| 2020-08-07 | 1607.81 | 未披露 | 定期报告 | 2020-08-04 |
| 2020-08-07 | 1607.10 | 未披露 |
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From March 31, 2020 to June 30, 2020
Issuance of common stock under employee stock compensation plans, net
|
2020-06-30 |
| 2020-04-24 | 1604.97 | 未披露 | 定期报告 | 2020-04-14 |
| 2020-05-08 | 1605.00 | 未披露 |
更多>>
From January 1, 2020 to March 31, 2020
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2020-03-31 |
| 2020-02-27 | 1650.52 | 未披露 | 定期报告 | 2020-02-21 |
| 2020-02-27 | 1682.30 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2019-12-31 |
| 2019-11-08 | 1756.34 | 未披露 | 定期报告 | 2019-11-06 |
| 2019-11-08 | 1756.30 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2019-09-30 |
| 2019-08-08 | 1901.15 | 未披露 | 定期报告 | 2019-08-07 |
| 2019-08-08 | 1939.00 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2019-06-30 |
| 2019-05-09 | 1959.84 | 未披露 | 定期报告 | 2019-05-07 |
| 2019-05-09 | 1966.39 | 未披露 |
更多>>
from January 1, 2019 to March 31, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2019-03-31 |
| 2019-02-28 | 2044.54 | 未披露 | 定期报告 | 2019-02-25 |
| 2019-02-28 | 2076.55 | 未披露 |
更多>>
from December 31, 2017 to December 31, 2018
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2018-12-31 |
| 2018-11-08 | 2125.37 | 未披露 | 定期报告 | 2018-11-06 |
| 2018-11-08 | 2109.52 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-08 | 2110.38 | 未披露 | 定期报告 | 2018-08-07 |
| 2018-08-08 | 2109.52 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-04-30 | 2130.14 | 未披露 | 定期报告 | 2018-04-20 |
| 2018-05-09 | 2130.20 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-03-01 | 2120.43 | 未披露 | 定期报告 | 2018-02-26 |
| 2018-03-01 | 2114.87 | 未披露 |
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from December 31, 2016 to December 31, 2017
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2017-12-31 |
| 2017-11-09 | 2110.55 | 未披露 | 定期报告 | 2017-10-31 |
| 2017-11-09 | 2109.48 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-09 | 2105.35 | 未披露 | 定期报告 | 2017-07-31 |
| 2017-08-09 | 2104.97 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-04-14 | 2096.37 | 未披露 | 定期报告 | 2017-04-07 |
| 2017-05-09 | 2099.60 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-02-28 | 2091.99 | 未披露 | 定期报告 | 2017-02-09 |
| 2017-02-28 | 2090.93 | 未披露 |
更多>>
from December 31, 2015 to December 31, 2016
Issuance of common stock under employee stock compensation plans, net
Shares issued in OMT acquisition
Repurchase of common stock
|
2016-12-31 |
| 2016-11-15 | 2090.02 | 未披露 | 定期报告 | 2016-11-01 |
| 2016-11-15 | 2089.89 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-04 | 2085.44 | 未披露 | 定期报告 | 2016-08-01 |
| 2016-08-04 | 2085.31 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-05-09 | 2082.24 | 未披露 | 定期报告 | 2016-05-01 |
| 2016-04-12 | 2081.56 | 未披露 | 定期报告 | 2016-03-29 |
| 2016-02-26 | 2077.31 | 未披露 | 定期报告 | 2016-02-17 |
| 2016-01-08 | 1994.97 | 未披露 | 定期报告 | 2016-01-07 |
| 2016-02-26 | 1994.90 | 未披露 |
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from December 31, 2014 to December 31, 2015
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2015-12-31 |
| 2015-11-09 | 1992.58 | 未披露 | 定期报告 | 2015-11-07 |
| 2015-11-09 | 1991.83 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-05 | 1985.48 | 未披露 | 定期报告 | 2015-08-01 |
| 2015-08-05 | 1983.71 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-05-11 | 1966.67 | 未披露 | 定期报告 | 2015-05-01 |
| 2015-05-11 | 1965.84 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-03-13 | 1963.99 | 未披露 | 定期报告 | 2015-02-23 |
| 2015-02-23 | 1957.76 | 未披露 | 定期报告 | 2015-02-17 |
| 2015-02-23 | 1957.52 | 未披露 |
更多>>
from December 31, 2013 to December 31, 2014
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2014-12-31 |
| 2014-12-01 | 1988.58 | 未披露 | 定期报告 | 2014-11-24 |
| 2014-10-31 | 2002.31 | 未披露 | 定期报告 | 2014-10-31 |
| 2014-10-31 | 2011.71 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-05 | 2078.08 | 未披露 | 定期报告 | 2014-08-05 |
| 2014-08-05 | 2077.85 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-05-07 | 2072.54 | 未披露 | 定期报告 | 2014-05-07 |
| 2014-05-07 | 2071.71 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-02-24 | 2061.45 | 未披露 | 定期报告 | 2014-02-14 |
| 2014-02-24 | 2046.85 | 未披露 |
更多>>
from December 31, 2012 to December 31, 2013
Issuance of common stock under employee stock compensation plans, net
Retirement of treasury shares
|
2013-12-31 |
| 2013-11-08 | 2041.02 | 未披露 | 定期报告 | 2013-10-29 |
| 2013-11-08 | 2041.01 | 未披露 | 定期报告 | 2013-09-30 |
| 2013-08-01 | 2044.09 | 未披露 | 定期报告 | 2013-08-01 |
| 2013-08-01 | 2031.76 | 未披露 | 定期报告 | 2013-06-30 |
| 2013-05-08 | 2023.50 | 未披露 | 定期报告 | 2013-05-01 |
| 2013-05-08 | 2022.47 | 未披露 | 定期报告 | 2013-03-31 |
| 2013-03-14 | 2020.82 | 未披露 | 定期报告 | 2013-03-01 |
| 2013-03-14 | 2016.04 | 未披露 |
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from December 31, 2011 to December 31, 2012
Issuance of common stock under employee stock compensation plans, net
Issuance of common stock, net
Shares released from restriction
|
2012-12-31 |
| 2012-11-14 | 1996.45 | 未披露 | 定期报告 | 2012-09-30 |
| 2012-08-08 | 1993.67 | 未披露 | 定期报告 | 2012-08-08 |
| 2012-08-08 | 1978.67 | 未披露 | 定期报告 | 2012-06-30 |
| 2012-05-04 | 1973.44 | 未披露 | 定期报告 | 2012-04-30 |
| 2012-05-04 | 1973.43 | 未披露 | 定期报告 | 2012-03-31 |
| 2012-02-23 | 1968.32 | 未披露 | 定期报告 | 2012-02-01 |
| 2012-02-23 | 1956.43 | 未披露 |
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from December 31, 2010 to December 31, 2011
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
|
2011-12-31 |
| 2011-11-08 | 1967.37 | 未披露 | 定期报告 | 2011-11-08 |
| 2011-11-08 | 1956.13 | 未披露 | 定期报告 | 2011-09-30 |
| 2011-08-08 | 1967.31 | 未披露 | 定期报告 | 2011-08-01 |
| 2011-08-08 | 1955.83 | 未披露 | 定期报告 | 2011-06-30 |
| 2011-05-10 | 1963.84 | 未披露 | 定期报告 | 2011-04-27 |
| 2011-05-10 | 1952.60 | 未披露 | 定期报告 | 2011-03-31 |
| 2011-03-03 | 1962.13 | 未披露 | 定期报告 | 2011-02-11 |
| 2011-03-03 | 1950.89 | 未披露 |
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from December 31 2009 to December 31 2010
Issuance of common stock under employee stock compensation plans
Repurchase of common stock
On November 19, 2010, following approval from the Company’s stockholders at a special meeting of stockholders on September 9, 2010, the Company announced a 1-for-6 reverse stock split of its common stock.
|
2010-12-31 |
| 2010-11-09 | 1961.02 | 未披露 | 定期报告 | 2010-10-31 |
| 2010-11-09 | 1951.80 | 未披露 |
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On November 8, 2010,the Company announced a 1-for-6 reverse stock split of its common stock.
|
2010-09-30 |
| 2010-08-05 | 12438.39 | 未披露 | 定期报告 | 2010-07-26 |
| 2010-08-05 | 11710.18 | 未披露 | 定期报告 | 2010-06-30 |
| 2010-05-05 | 11757.91 | 未披露 | 定期报告 | 2010-03-31 |
| 2010-03-03 | 11733.53 | 未披露 | 定期报告 | 2010-02-11 |
| 2010-03-03 | 11733.53 | 未披露 |
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from December 31, 2008 to December 31, 2009
Issuance of common stock under employee stock compensation plans
Issuance of common stock for acquisition of Neurogen
|
2009-12-31 |
| 2009-03-16 | 11329.28 | 未披露 | 定期报告 | 2009-02-27 |
| 2009-03-16 | 11295.24 | 未披露 |
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from December 31, 2007 to December 31, 2008
Issuance of common stock under employee stock compensation plans
Issuance of common stock for acquisition of Pharmacopeia
Repurchase of Company common stock
|
2008-12-31 |
| 2008-03-05 | 9496.31 | 未披露 | 定期报告 | 2008-01-31 |
| 2008-03-05 | 9527.78 | 未披露 |
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from January 1, 2007 to December 31, 2007
Issuance of common stock under employee stock compensation plans
Repurchase of Company common stock
|
2007-12-31 |
| 2007-03-16 | 10100.83 | 未披露 | 定期报告 | 2007-02-28 |
| 2007-03-16 | 10047.72 | 未披露 |
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from December 31, 2005 to December 31, 2006
Issuance of common stock upon exercise of stock options and restricted stock grants
Issuance of common stock on conversion of debt
|
2006-12-31 |
| 2006-03-31 | 7808.27 | 未披露 | 定期报告 | 2006-02-28 |
| 2006-03-31 | 7406.01 | 未披露 |
更多>>
from December 31, 2004 to December 31, 2005
Issuance of common stock
|
2005-12-31 |
| 2005-11-18 | 7413.13 | 未披露 | 定期报告 | 2005-10-31 |
| 2005-11-18 | 7389.44 | 未披露 |
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from December 31, 2003 to December 31, 2004
Issuance of common stock
|
2004-12-31 |
| 2004-03-12 | 7335.85 | 未披露 | 定期报告 | 2004-02-27 |
| 2004-03-12 | 7319.09 | 未披露 |
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from December 31, 2002 to December 31, 2003
Issuance of common stock
Repurchase of common stock
|
2003-12-31 |
| 2003-03-21 | 6922.61 | 未披露 | 定期报告 | 2003-02-28 |
| 2003-03-21 | 7144.83 | 未披露 |
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from December 31, 2001 to December 31, 2002
Issuance of common stock
|
2002-12-31 |
| 2002-03-19 | 6454.51 | 未披露 | 定期报告 | 2002-02-28 |
| 2002-03-19 | 6009.10 | 未披露 |
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from December 31, 2000 to December 31, 2001
Issuance of Common Stock
|
2001-12-31 |
| 2001-03-29 | 5879.16 | 未披露 | 定期报告 | 2001-02-28 |
| 2001-03-29 | 5674.99 | 未披露 |
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from December 31, 1999 to December 31, 2000
Issuance of Common Stock
Stock received for milestone payment
|
2000-12-31 |
| 2000-03-29 | 5324.91 | 未披露 | 定期报告 | 2000-02-29 |
| 2000-03-29 | 5301.71 | 未披露 |
更多>>
from December 31, 1998 to December 31, 1999
Issuance of Common Stock
the number of shares of Common Stock shall have been increased by a subdivision or split-up of shares of Common Stock
|
1999-12-31 |
| 1999-03-31 | 4615.18 | 未披露 | 定期报告 | 1999-02-28 |
| 1999-03-31 | 4568.90 | 未披露 |
更多>>
from December 31, 1997 to December 31, 1998
Issuance of Common Stock
|
1998-12-31 |
| 1998-03-31 | 3859.50 | 未披露 | 定期报告 | 1998-02-28 |
| 1998-03-31 | 3850.33 | 未披露 |
更多>>
from December 31, 1996 to December 31, 1997
Issuance of Common Stock
|
1997-12-31 |
| 1997-03-31 | 3201.76 | 未披露 | 定期报告 | 1997-02-28 |
| 1997-03-31 | 3179.85 | 未披露 |
更多>>
from December 31, 1995 to December 31, 1996
Issuance of common stock
Receipt of common stock for milestone revenue
Retirement of shares
Purchase of treasury shares
Issuance of common stock held in treasury
|
1996-12-31 |
| 1997-03-31 | 2779.56 | 未披露 |
更多>>
from December 31, 1994 to December 31, 1995
Issuance of Common Stock
Issuance of Common Stock for merger net of transaction costs of $1,235,000
Purchase of treasury stock
|
1995-12-31 |
From June 30, 2025 to September 30, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Share repurchase in connection to the 2030 Notes
From March 31, 2025 to June 30, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2024 to March 31, 2025
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2023 to December 31, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Issuance of common stock, net of commissions and fees
From June 30, 2024 to September 30, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
Issuance of common stock under ATM, net of commissions and fees
From March 31, 2024 to June 30, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2023 to March 31, 2024
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2022 to December 31, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From June 30, 2023 to September 30, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From March 31, 2023 to June 30, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2022 to March 31, 2023
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2021 to December 31, 2022
Issuance of common stock under employee stock compensation plans, net
From June 30, 2022 to September 30, 2022
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From March 31, 2022 to June 30, 2022
Issuance of common stock under employee stock compensation plans, net
From December 31, 2021 to March 31, 2022
Issuance of common stock under employee stock compensation plans, net of shares withheld for payroll taxes
From December 31, 2020 to December 31, 2021
Issuance of common stock under employee stock compensation plans, net
From June 30, 2021 to September 30, 2021
Issuance of common stock under employee stock compensation plans, net
From March 31, 2021 to June 30, 2021
Issuance of common stock under employee stock compensation plans, net
From January 1, 2021 To March 31, 2021
Issuance of common stock under employee stock compensation plans, net
From December 31, 2019 to December 31, 2020
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
From June 30, 2020 to September 30, 2020
Issuance of common stock under employee stock compensation plans,net
From March 31, 2020 to June 30, 2020
Issuance of common stock under employee stock compensation plans, net
From January 1, 2020 to March 31, 2020
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
From December 31, 2018 to December 31, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from June 30, 2019 to September 30, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
From March 31, 2019 to June 30, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from January 1, 2019 to March 31, 2019
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31, 2017 to December 31, 2018
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31, 2016 to December 31, 2017
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31, 2015 to December 31, 2016
Issuance of common stock under employee stock compensation plans, net
Shares issued in OMT acquisition
Repurchase of common stock
from December 31, 2014 to December 31, 2015
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31, 2013 to December 31, 2014
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31, 2012 to December 31, 2013
Issuance of common stock under employee stock compensation plans, net
Retirement of treasury shares
from December 31, 2011 to December 31, 2012
Issuance of common stock under employee stock compensation plans, net
Issuance of common stock, net
Shares released from restriction
from December 31, 2010 to December 31, 2011
Issuance of common stock under employee stock compensation plans, net
Repurchase of common stock
from December 31 2009 to December 31 2010
Issuance of common stock under employee stock compensation plans
Repurchase of common stock
On November 19, 2010, following approval from the Company’s stockholders at a special meeting of stockholders on September 9, 2010, the Company announced a 1-for-6 reverse stock split of its common stock.
On November 8, 2010,the Company announced a 1-for-6 reverse stock split of its common stock.
from December 31, 2008 to December 31, 2009
Issuance of common stock under employee stock compensation plans
Issuance of common stock for acquisition of Neurogen
from December 31, 2007 to December 31, 2008
Issuance of common stock under employee stock compensation plans
Issuance of common stock for acquisition of Pharmacopeia
Repurchase of Company common stock
from January 1, 2007 to December 31, 2007
Issuance of common stock under employee stock compensation plans
Repurchase of Company common stock
from December 31, 2005 to December 31, 2006
Issuance of common stock upon exercise of stock options and restricted stock grants
Issuance of common stock on conversion of debt
from December 31, 2004 to December 31, 2005
Issuance of common stock
from December 31, 2003 to December 31, 2004
Issuance of common stock
from December 31, 2002 to December 31, 2003
Issuance of common stock
Repurchase of common stock
from December 31, 2001 to December 31, 2002
Issuance of common stock
from December 31, 2000 to December 31, 2001
Issuance of Common Stock
from December 31, 1999 to December 31, 2000
Issuance of Common Stock
Stock received for milestone payment
from December 31, 1998 to December 31, 1999
Issuance of Common Stock
the number of shares of Common Stock shall have been increased by a subdivision or split-up of shares of Common Stock
from December 31, 1997 to December 31, 1998
Issuance of Common Stock
from December 31, 1996 to December 31, 1997
Issuance of Common Stock
from December 31, 1995 to December 31, 1996
Issuance of common stock
Receipt of common stock for milestone revenue
Retirement of shares
Purchase of treasury shares
Issuance of common stock held in treasury
from December 31, 1994 to December 31, 1995
Issuance of Common Stock
Issuance of Common Stock for merger net of transaction costs of $1,235,000
Purchase of treasury stock