股本结构
单位：万股
| 公告日期 | 2025-12-08 | 2025-11-04 | 2025-11-04 | 2025-08-06 | 2025-08-06 | 2025-05-07 |
|---|---|---|---|---|---|---|
| 证券总股本 | 5168.38 | 5139.36 | 5131.42 | 5023.76 | 5005.84 | 4953.47 |
| 普通股本 | 5168.38 | 5139.36 | 5131.42 | 5023.76 | 5005.84 | 4953.47 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-12-04 | 2025-10-31 | 2025-09-30 | 2025-08-01 | 2025-06-30 | 2025-05-02 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-12-08 | 5168.38 | 未披露 | 定期报告 | 2025-12-04 |
| 2025-11-04 | 5139.36 | 未披露 | 定期报告 | 2025-10-31 |
| 2025-11-04 | 5131.42 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with equity award plans
Conversion of convertible notes, net
|
2025-09-30 |
| 2025-08-06 | 5023.76 | 未披露 | 定期报告 | 2025-08-01 |
| 2025-08-06 | 5005.84 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with equity award plans
Issuance of common stock in connection with employee stock purchase plan
Conversion of convertible notes, net
|
2025-06-30 |
| 2025-05-07 | 4953.47 | 未披露 | 定期报告 | 2025-05-02 |
| 2025-04-14 | 4945.43 | 未披露 | 定期报告 | 2025-04-03 |
| 2025-05-07 | 4945.12 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Conversion of convertible notes, net
Issuance of common stock in connection with equity award plans
|
2025-03-31 |
| 2025-02-26 | 4901.42 | 未披露 | 定期报告 | 2025-02-21 |
| 2025-04-14 | 4899.09 | 未披露 | 定期报告 | 2025-02-15 |
| 2025-02-26 | 4833.81 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
|
2024-12-31 |
| 2024-11-12 | 4800.46 | 未披露 | 定期报告 | 2024-11-08 |
| 2024-11-12 | 4796.81 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock in connection with equity award plans
|
2024-09-30 |
| 2024-08-07 | 4770.72 | 未披露 | 定期报告 | 2024-08-02 |
| 2024-08-07 | 4757.18 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
|
2024-06-30 |
| 2024-05-08 | 4713.30 | 未披露 | 定期报告 | 2024-05-03 |
| 2024-04-23 | 4711.84 | 未披露 | 定期报告 | 2024-04-10 |
| 2024-05-08 | 4706.11 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock in connection with equity award plans
|
2024-03-31 |
| 2024-03-15 | 4700.33 | 未披露 | 定期报告 | 2024-03-08 |
| 2024-04-23 | 4698.82 | 未披露 | 定期报告 | 2024-02-15 |
| 2024-03-15 | 4672.31 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock in connection with asset acquisition
Issuance of common stock in private placement, net of issuance costs of $7,796
Issuance of common stock in at-the-market offerings, net of issuance costs of $518
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
|
2023-12-31 |
| 2023-11-02 | 4661.43 | 未披露 | 定期报告 | 2023-10-27 |
| 2023-11-02 | 4659.57 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock in connection with equity award plans
Issuance of common stock in private placement, net of issuance costs of $7,761
|
2023-09-30 |
| 2023-10-13 | 4643.82 | 未披露 | 定期报告 | 2023-08-31 |
| 2023-08-07 | 3829.80 | 未披露 | 定期报告 | 2023-07-28 |
| 2023-08-07 | 3822.21 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock in connection with settlement of Indemnification Holdback liability
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
|
2023-06-30 |
| 2023-05-04 | 3803.18 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-05-01 | 3803.07 | 未披露 | 定期报告 | 2023-04-17 |
| 2023-05-04 | 3801.22 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with equity award plans
Issuance of common stock in at-the-market offerings, net of issuance costs of $518
Issuance of common stock in connection with achievement of Contingent Milestone
|
2023-03-31 |
| 2023-03-08 | 3795.10 | 未披露 | 定期报告 | 2023-03-03 |
| 2023-03-08 | 3695.63 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock in connection with equity incentive plans
Issuance of common stock in connection with Employee Stock Purchase Plan
Issuance of common stock in connection with asset acquisition
Issuance of common stock in at-the-market offerings, net of issuance costs of $785
Issuance of common stock in connection with public offering, net of issuance costs $5,922
Restricted common stock vested in the period
|
2022-12-31 |
| 2022-11-09 | 3687.04 | 未披露 | 定期报告 | 2022-11-04 |
| 2022-11-09 | 3683.60 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Restricted common stock vested in the period
Issuance of common stock in connection with equity award plans
Issuance of common stock in public offerings, net of issuance costs of $5,922
|
2022-09-30 |
| 2022-08-12 | 3623.00 | 未披露 |
更多>>
1.Common stock offered by 3,478,261 shares of common stock
2.The number of shares of common stock to be outstanding after this offering set forth above is based on 32,744,923 shares of common stock outstanding as of June 30, 2022
|
2022-08-12 |
| 2022-08-04 | 3275.17 | 未披露 | 定期报告 | 2022-08-01 |
| 2022-08-04 | 3274.49 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock in connection with asset acquisition
Issuance of common stock in connection with employee stock purchase plan
Restricted common stock vested in the period
Issuance of common stock in connection with equity award plans
Issuance of common stock in at-the-market offerings, net of issuance costs of $184
|
2022-06-30 |
| 2022-05-25 | 3194.08 | 未披露 | 定期报告 | 2022-05-18 |
| 2022-05-05 | 3183.54 | 未披露 | 定期报告 | 2022-05-02 |
| 2022-04-22 | 3181.60 | 未披露 | 定期报告 | 2022-04-08 |
| 2022-05-05 | 3180.19 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock in connection with equity award plans
Issuance of common stock in public offering, net of issuance costs of $601
Restricted common stock vested in the period
|
2022-03-31 |
| 2022-03-09 | 3173.04 | 未披露 | 定期报告 | 2022-03-04 |
| 2022-03-09 | 3070.51 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock in connection with equity award plans
Issuance of common stock in connection with public offering, net of issuance costs $476,000
Restricted common stock vested in the period
Issuance of common stock in connection with Employee Stock Purchase Plan
|
2021-12-31 |
| 2021-11-15 | 3063.82 | 未披露 | 定期报告 | 2021-11-10 |
| 2021-11-15 | 3056.22 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
|
2021-09-30 |
| 2021-08-05 | 3051.58 | 未披露 | 定期报告 | 2021-07-30 |
| 2021-08-05 | 3050.64 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
Issuance of shares in connection with ESPP
|
2021-06-30 |
| 2021-05-06 | 3045.34 | 未披露 | 定期报告 | 2021-04-30 |
| 2021-04-14 | 3044.18 | 未披露 | 定期报告 | 2021-04-07 |
| 2021-05-06 | 3042.08 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of common stock in connection with common stock option exercises
Issuance of common stock in public offering, net of issuance costs of $25
Restricted common stock vested in the period
|
2021-03-31 |
| 2021-03-09 | 3041.97 | 未披露 | 定期报告 | 2021-03-05 |
| 2021-03-09 | 3003.26 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Issuance of common stock in underwritten public offerings, net of issuance costs of $8,322
Issuance of common stock in connection with Revenue Interest Purchase Agreement
Issuance of common stock in at-the-market offerings, net of issuance costs of $314
Issuance of common stock in connection with common stock option exercises
Issuance of common stock in connection with Employee Stock Purchase Plan
Restricted common stock vested in the period
|
2020-12-31 |
| 2020-12-17 | 2925.03 | 未披露 |
更多>>
1.Common stock offered by the company 3,750,000 shares of our common stock.
2.The number of shares of common stock to be outstanding after this offering set forth above is based on 25,500,340 shares of common stock outstanding as of September 30, 2020.
|
2020-12-17 |
| 2020-11-12 | 2571.69 | 未披露 | 定期报告 | 2020-11-06 |
| 2020-11-12 | 2550.03 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock in at-the-market offering, net of issuance costs of $138
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
|
2020-09-30 |
| 2020-08-06 | 2539.91 | 未披露 | 定期报告 | 2020-07-31 |
| 2020-08-06 | 2539.42 | 未披露 |
更多>>
from March 31, 2020 to June 30, 2020
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
|
2020-06-30 |
| 2020-05-07 | 2539.00 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Issuance of common stock in follow-on public offering, net of issuance costs of $3,342
Restricted common stock vested in the period
|
2020-03-31 |
| 2020-01-13 | 2539.00 | 未披露 | 定期报告 | 2020-01-13 |
| 2020-03-12 | 2299.00 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of Series A redeemable convertible preferred stock at $1.00259507 per share, net of issuance costs of $23
Issuance of common stock in initial public offering, net of issuance costs of $7,800
Conversion of Series A redeemable convertible preferred stock into common stock on initial public offering
Reclassification of redeemable common stock into common stock on initial public offering
Restricted common stock vested in the period
|
2019-12-31 |
| 2019-11-06 | 2256.69 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Conversion of Series A redeemable convertible preferred stock into common stock on initial public offering
Reclassification of redeemable common stock into common stock on initial public offering
Issuance of common stock in initial public offering, net of issuance costs of $7,800
|
2019-09-30 |
| 2019-08-28 | 2299.00 | 未披露 | 定期报告 | 2019-08-26 |
| 2019-07-18 | 2301.58 | 未披露 |
更多>>
1.Common stock offered 5,000,000 shares
2.The number of shares of our common stock to be outstanding after this offering set forth above is based on 18,015,769 shares of our common stock outstanding as of March 31, 2019
3.a 1-for-8 reverse stock split of our common stock effected on July 3, 2019
|
2019-07-18 |
| 2019-08-28 | 302.09 | 11975.30 |
更多>>
from March 31, 2019 to June 30, 2019
Issuance of Series A redeemable convertible preferred stock at $1.00259507 per share,net of issuance costs of $23
|
2019-06-30 |
| 2019-06-21 | 537.50 | 未披露 |
更多>>
from December 31, 2018 to March 31, 2019
Restricted common stock vested in the period
|
2019-03-31 |
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with equity award plans
Conversion of convertible notes, net
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with equity award plans
Issuance of common stock in connection with employee stock purchase plan
Conversion of convertible notes, net
From December 31, 2024 to March 31, 2025
Conversion of convertible notes, net
Issuance of common stock in connection with equity award plans
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
From June 30, 2024 to September 30, 2024
Issuance of common stock in connection with equity award plans
From March 31, 2024 to June 30, 2024
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
From December 31, 2023 to March 31, 2024
Issuance of common stock in connection with equity award plans
From December 31, 2022 to December 31, 2023
Issuance of common stock in connection with asset acquisition
Issuance of common stock in private placement, net of issuance costs of $7,796
Issuance of common stock in at-the-market offerings, net of issuance costs of $518
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
From June 30, 2023 to September 30, 2023
Issuance of common stock in connection with equity award plans
Issuance of common stock in private placement, net of issuance costs of $7,761
From March 31, 2023 to June 30, 2023
Issuance of common stock in connection with settlement of Indemnification Holdback liability
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock in connection with equity award plans
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with equity award plans
Issuance of common stock in at-the-market offerings, net of issuance costs of $518
Issuance of common stock in connection with achievement of Contingent Milestone
From December 31, 2021 to December 31, 2022
Issuance of common stock in connection with equity incentive plans
Issuance of common stock in connection with Employee Stock Purchase Plan
Issuance of common stock in connection with asset acquisition
Issuance of common stock in at-the-market offerings, net of issuance costs of $785
Issuance of common stock in connection with public offering, net of issuance costs $5,922
Restricted common stock vested in the period
From June 30, 2022 to September 30, 2022
Restricted common stock vested in the period
Issuance of common stock in connection with equity award plans
Issuance of common stock in public offerings, net of issuance costs of $5,922
1.Common stock offered by 3,478,261 shares of common stock
2.The number of shares of common stock to be outstanding after this offering set forth above is based on 32,744,923 shares of common stock outstanding as of June 30, 2022
From March 31, 2022 to June 30, 2022
Issuance of common stock in connection with asset acquisition
Issuance of common stock in connection with employee stock purchase plan
Restricted common stock vested in the period
Issuance of common stock in connection with equity award plans
Issuance of common stock in at-the-market offerings, net of issuance costs of $184
From December 31, 2021 to March 31, 2022
Issuance of common stock in connection with equity award plans
Issuance of common stock in public offering, net of issuance costs of $601
Restricted common stock vested in the period
From December 31, 2020 to December 31, 2021
Issuance of common stock in connection with equity award plans
Issuance of common stock in connection with public offering, net of issuance costs $476,000
Restricted common stock vested in the period
Issuance of common stock in connection with Employee Stock Purchase Plan
From June 30, 2021 to September 30, 2021
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
From March 31, 2021 to June 30, 2021
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
Issuance of shares in connection with ESPP
From December 31, 2020 to March 31, 2021
Issuance of common stock in connection with common stock option exercises
Issuance of common stock in public offering, net of issuance costs of $25
Restricted common stock vested in the period
From December 31, 2019 to December 31, 2020
Issuance of common stock in underwritten public offerings, net of issuance costs of $8,322
Issuance of common stock in connection with Revenue Interest Purchase Agreement
Issuance of common stock in at-the-market offerings, net of issuance costs of $314
Issuance of common stock in connection with common stock option exercises
Issuance of common stock in connection with Employee Stock Purchase Plan
Restricted common stock vested in the period
1.Common stock offered by the company 3,750,000 shares of our common stock.
2.The number of shares of common stock to be outstanding after this offering set forth above is based on 25,500,340 shares of common stock outstanding as of September 30, 2020.
From June 30, 2020 to September 30, 2020
Issuance of common stock in at-the-market offering, net of issuance costs of $138
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
from March 31, 2020 to June 30, 2020
Issuance of common stock in connection with common stock option exercises
Restricted common stock vested in the period
From December 31, 2019 to March 31, 2020
Issuance of common stock in follow-on public offering, net of issuance costs of $3,342
Restricted common stock vested in the period
from December 31, 2018 to December 31, 2019
Issuance of Series A redeemable convertible preferred stock at $1.00259507 per share, net of issuance costs of $23
Issuance of common stock in initial public offering, net of issuance costs of $7,800
Conversion of Series A redeemable convertible preferred stock into common stock on initial public offering
Reclassification of redeemable common stock into common stock on initial public offering
Restricted common stock vested in the period
from June 30, 2019 to September 30, 2019
Conversion of Series A redeemable convertible preferred stock into common stock on initial public offering
Reclassification of redeemable common stock into common stock on initial public offering
Issuance of common stock in initial public offering, net of issuance costs of $7,800
1.Common stock offered 5,000,000 shares
2.The number of shares of our common stock to be outstanding after this offering set forth above is based on 18,015,769 shares of our common stock outstanding as of March 31, 2019
3.a 1-for-8 reverse stock split of our common stock effected on July 3, 2019
from March 31, 2019 to June 30, 2019
Issuance of Series A redeemable convertible preferred stock at $1.00259507 per share,net of issuance costs of $23
from December 31, 2018 to March 31, 2019
Restricted common stock vested in the period