股本结构
单位：万股
| 公告日期 | 2025-11-05 | 2025-11-05 | 2025-08-06 | 2025-08-06 | 2025-05-08 | 2025-05-08 |
|---|---|---|---|---|---|---|
| 证券总股本 | 30707.03 | 30702.72 | 30682.83 | 30633.21 | 30393.29 | 30391.90 |
| 普通股本 | 30707.03 | 30702.72 | 30682.83 | 30633.21 | 30393.29 | 30391.90 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-10-24 | 2025-09-30 | 2025-07-25 | 2025-06-30 | 2025-04-25 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-11-05 | 30707.03 | 未披露 | 定期报告 | 2025-10-24 |
| 2025-11-05 | 30702.72 | 未披露 |
更多>>
From JUNE 30, 2025 to SEPTEMBER 30, 2025
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase plan
|
2025-09-30 |
| 2025-08-06 | 30682.83 | 未披露 | 定期报告 | 2025-07-25 |
| 2025-08-06 | 30633.21 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under employee stock purchase plan
Issuance of common stock from market price stock purchase plan
|
2025-06-30 |
| 2025-05-08 | 30393.29 | 未披露 | 定期报告 | 2025-04-25 |
| 2025-05-08 | 30391.90 | 未披露 |
更多>>
From JANUARY 1, 2025 to March 31, 2025
Net issuance of common stock associated with stock options and restricted stock units
|
2025-03-31 |
| 2025-04-01 | 30385.56 | 未披露 | 定期报告 | 2025-03-20 |
| 2025-04-01 | 30384.54 | 未披露 | 定期报告 | 2025-03-17 |
| 2025-02-26 | 30359.13 | 未披露 | 定期报告 | 2025-02-14 |
| 2025-02-26 | 30295.98 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Net issuance of common stock associated with restricted stock units and stock options
Issuance of common stock pursuant to conversion of Mann Group convertible note principal
Issuance of common stock pursuant to conversion of Mann Group convertible note interest
Issuance of common stock pursuant to conversion of senior convertible note principal
Issuance of common stock under employee stock purchase plan
Issuance of common stock from market price stock purchase plan
|
2024-12-31 |
| 2024-11-07 | 27577.77 | 未披露 | 定期报告 | 2024-10-25 |
| 2024-11-07 | 27577.50 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Net issuance of common stock associated with stock options and restricted stock units
|
2024-09-30 |
| 2024-08-07 | 27499.50 | 未披露 | 定期报告 | 2024-07-26 |
| 2024-08-07 | 27446.72 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock pursuant to conversion of the Mann Group convertible note principal and interest
Issuance of common stock under employee stock purchase plan
Net issuance of common stock associated with stock options and restricted stock units
|
2024-06-30 |
| 2024-05-08 | 27231.58 | 未披露 | 定期报告 | 2024-04-26 |
| 2024-05-08 | 27080.18 | 未披露 |
更多>>
From January 1, 2024 to March 31, 2024
Issuance of common stock from market price stock purchase plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
|
2024-03-31 |
| 2024-04-05 | 27076.28 | 未披露 | 定期报告 | 2024-03-21 |
| 2024-04-05 | 27067.93 | 未披露 | 定期报告 | 2024-03-18 |
| 2024-02-27 | 27041.82 | 未披露 | 定期报告 | 2024-02-16 |
| 2024-02-27 | 27003.45 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of at-the-market offering
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from market price stock purchase plan
Net issuance of common stock associated with restricted stock units and stock options
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
|
2023-12-31 |
| 2023-11-07 | 26957.47 | 未披露 | 定期报告 | 2023-10-27 |
| 2023-11-07 | 26954.35 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock associated at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
|
2023-09-30 |
| 2023-08-07 | 26835.52 | 未披露 | 定期报告 | 2023-07-28 |
| 2023-08-07 | 26823.51 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock associated at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock under Employee Stock Purchase Plan
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase plan
|
2023-06-30 |
| 2023-05-09 | 26430.55 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-05-09 | 26427.88 | 未披露 |
更多>>
From January 1, 2023 to March 31, 2023
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of at-the-market placement
Net issuance of common stock associated with stock options and restricted stock units
|
2023-03-31 |
| 2023-04-10 | 26424.89 | 未披露 | 定期报告 | 2023-03-23 |
| 2023-02-23 | 26392.37 | 未披露 | 定期报告 | 2023-02-10 |
| 2023-02-23 | 26379.33 | 未披露 |
更多>>
From December 31, 2021 to December 31,2022
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of at-the-market placement
Issuance of common stock from market price stock purchase plan
|
2022-12-31 |
| 2022-11-08 | 26319.56 | 未披露 | 定期报告 | 2022-10-28 |
| 2022-11-08 | 26315.62 | 未披露 |
更多>>
From JUNE 30, 2022 to SEPTEMBER 30, 2022
Issuance of at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
|
2022-09-30 |
| 2022-08-09 | 25733.83 | 未披露 | 定期报告 | 2022-07-29 |
| 2022-08-09 | 25727.68 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock pursuant to conversion of Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
|
2022-06-30 |
| 2022-05-05 | 25256.54 | 未披露 | 定期报告 | 2022-04-29 |
| 2022-05-05 | 25241.34 | 未披露 |
更多>>
From JANUARY 1, 2022 to MARCH 31, 2022
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from market price stock purchase plan
|
2022-03-31 |
| 2022-03-30 | 25225.55 | 未披露 | 定期报告 | 2022-03-11 |
| 2022-02-24 | 25179.83 | 未披露 | 定期报告 | 2022-02-11 |
| 2022-02-24 | 25147.76 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock pursuant to conversion of the 2024 convertible notes
Issuance of common stock pursuant to payoff of the 2024 convertible note interest
Issuance of at-the-market placement
Issuance of common stock from market price stock purchase
Issuance of common stock pursuant to a warrant conversion
|
2021-12-31 |
| 2021-11-09 | 25125.64 | 未披露 | 定期报告 | 2021-10-29 |
| 2021-11-09 | 25024.58 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
|
2021-09-30 |
| 2021-08-11 | 24966.02 | 未披露 | 定期报告 | 2021-07-30 |
| 2021-08-11 | 24961.76 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase
|
2021-06-30 |
| 2021-05-12 | 24915.74 | 未披露 | 定期报告 | 2021-04-30 |
| 2021-05-12 | 24907.27 | 未披露 |
更多>>
From JANUARY 1, 2021 to MARCH 31, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock pursuant to conversion of the 2024 convertible notes
Issuance of common stock pursuant to payoff of the 2024 convertible note interest
Issuance of at-the-market placement
|
2021-03-31 |
| 2021-04-07 | 24907.27 | 未披露 | 定期报告 | 2021-03-22 |
| 2021-02-25 | 24715.83 | 未披露 | 定期报告 | 2021-02-12 |
| 2021-02-25 | 24211.71 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Payment of principal on senior convertible notes through common stock issuance
Payment of interest on senior convertible notes through common stock issuance
Issuance of common stock pursuant to conversion of Mann Group convertible note principal
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from acquisition
Issuance of common stock from the exercise of warrants
Issuance of common stock from market price stock purchase
|
2020-12-31 |
| 2020-11-04 | 23260.06 | 未披露 | 定期报告 | 2020-10-26 |
| 2020-11-04 | 23092.25 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock associated with debt interest payment
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock under Employee Stock Purchase Plan
|
2020-09-30 |
| 2020-08-05 | 22917.49 | 未披露 | 定期报告 | 2020-07-13 |
| 2020-08-05 | 22892.75 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock from the exercise of warrants
Issuance of common stock pursuant to conversion of the June 2020 note
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock from market price stock purchase
Adjustment of common stock in association with restricted stock units
|
2020-06-30 |
| 2020-05-06 | 21313.77 | 未披露 | 定期报告 | 2020-04-13 |
| 2020-05-06 | 21313.77 | 未披露 |
更多>>
from JANUARY 1, 2020 to March 31, 2020
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock associated with debt interest payment
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at-the-market offering
|
2020-03-31 |
| 2020-04-10 | 21312.86 | 未披露 | 定期报告 | 2020-03-22 |
| 2020-02-25 | 21229.53 | 未披露 | 定期报告 | 2020-02-13 |
| 2020-02-25 | 21178.76 | 未披露 |
更多>>
from December 31, 2018 to DECEMBER 31, 2019
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of Deerfield Credit Facility
Issuance of common stock from the release of restricted stock units
Issuance of common stock pursuant to conversion of Mann Group promissory notes
Issuance of common stock pursuant to conversion of senior convertible notes
Issuance of common stock in at-the-market offering
Issuance of common stock from the exercise of warrants
|
2019-12-31 |
| 2019-11-08 | 20640.82 | 未披露 | 定期报告 | 2019-10-31 |
| 2019-11-08 | 20640.76 | 未披露 |
更多>>
From June 30, 2019 to September 30, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of Senior Convertible Notes
Issuance of common stock pursuant to conversion of Facility Financing Obligation
Issuance of common stock pursuant to conversion of Promissory Notes
Issuance of common stock in at-the-market offering
|
2019-09-30 |
| 2019-08-07 | 18961.61 | 未披露 | 定期报告 | 2019-07-16 |
| 2019-08-07 | 18944.71 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of at-the-market placement
|
2019-06-30 |
| 2019-05-07 | 18778.26 | 未披露 | 定期报告 | 2019-04-15 |
| 2019-05-07 | 18777.82 | 未披露 |
更多>>
from January 1, 2019 to March 31, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of shares pursuant to conversion of Senior Convertible Notes
|
2019-03-31 |
| 2019-03-28 | 18777.40 | 未披露 | 定期报告 | 2019-03-15 |
| 2019-02-26 | 18734.26 | 未披露 | 定期报告 | 2019-02-14 |
| 2019-02-26 | 18703.00 | 未披露 |
更多>>
from December 31, 2017 to DECEMBER 31, 2018
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of direct placement — common stock
Issuance of ATM placement
Issuance of shares pursuant to conversion of Note Payable to Related Party
Issuance of shares pursuant to conversion of Facility Financing Obligation
Issuance of shares pursuant to conversion of Senior Convertible Notes
Issuance of shares under Market Price Stock Purchase Plan
|
2018-12-31 |
| 2018-11-01 | 15959.76 | 未披露 | 定期报告 | 2018-10-22 |
| 2018-11-01 | 15949.76 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-02 | 15298.84 | 未披露 | 定期报告 | 2018-07-17 |
| 2018-08-02 | 14561.93 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-09 | 14002.54 | 未披露 | 定期报告 | 2018-04-24 |
| 2018-05-09 | 12601.31 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-03-29 | 12301.14 | 未披露 | 定期报告 | 2018-03-19 |
| 2018-02-27 | 12046.71 | 未披露 | 定期报告 | 2018-02-09 |
| 2018-02-27 | 11905.34 | 未披露 |
更多>>
from December 31, 2016 to DECEMBER 31, 2017
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of shares pursuant to conversion of notes
Issuance of direct placement — common stock
Issuance of ATM placement
Reclassification of warrant liability to equity
|
2017-12-31 |
| 2017-11-17 | 11887.06 | 未披露 | 定期报告 | 2017-11-09 |
| 2017-11-07 | 11714.71 | 未披露 | 定期报告 | 2017-10-31 |
| 2017-11-07 | 10470.71 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-07 | 10468.27 | 未披露 | 定期报告 | 2017-08-01 |
| 2017-08-07 | 10461.60 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-05-10 | 10100.63 | 未披露 | 定期报告 | 2017-05-05 |
| 2017-05-10 | 9577.63 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-03-16 | 9577.62 | 未披露 | 定期报告 | 2017-03-10 |
| 2017-03-16 | 9568.08 | 未披露 |
更多>>
from December 31, 2015 to March 3, 2017
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of direct placement — common stock and warrants
March 1, 2017, following stockholder approval of the Reverse Split Proposal, the Company’s board of directors approved a reverse stock split of the Company’s common stock at a ratio of 1-for-5. The Company’s common stock will begin trading on The NASDAQ Global Market on a split-adjusted basis when the market opens on March 3, 2017.
|
2017-03-03 |
| 2017-02-13 | 47863.71 | 未披露 | 定期报告 | 2017-02-01 |
| 2016-11-09 | 47837.69 | 未披露 | 定期报告 | 2016-11-01 |
| 2016-11-09 | 47836.25 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-09 | 47804.84 | 未披露 | 定期报告 | 2016-08-01 |
| 2016-08-09 | 47774.19 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-05-09 | 42916.13 | 未披露 | 定期报告 | 2016-05-02 |
| 2016-05-09 | 42913.87 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-04-21 | 42885.62 | 未披露 | 定期报告 | 2016-03-21 |
| 2016-03-15 | 42885.09 | 未披露 | 定期报告 | 2016-02-22 |
| 2016-03-15 | 42867.09 | 未披露 |
更多>>
From December 31, 2014 to December 31, 2015
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to conversions of certain 2015 notes
Issuance of common stock for lender financing fees
Issuance of common stock pursuant to TASE stock sale
Return of loaned common stock
Issuance of common stock pursuant to at-the-market issuances
Issuance of common shares under Employee Stock Purchase Plan
|
2015-12-31 |
| 2015-11-09 | 40948.67 | 未披露 | 定期报告 | 2015-11-02 |
| 2015-11-09 | 41826.38 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-09-04 | 41475.74 | 未披露 | 定期报告 | 2015-09-02 |
| 2015-08-10 | 41403.39 | 未披露 | 定期报告 | 2015-08-07 |
| 2015-08-10 | 41231.66 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-05-11 | 40957.68 | 未披露 | 定期报告 | 2015-05-04 |
| 2015-05-11 | 40911.63 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-04-10 | 40910.25 | 未披露 | 定期报告 | 2015-03-22 |
| 2015-03-02 | 40883.76 | 未披露 | 定期报告 | 2015-02-23 |
| 2015-03-02 | 40605.91 | 未披露 |
更多>>
From December 31,2013 to December 31,2014
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to debt conversions by Deerfield
Issuance of common shares under Employee Stock Purchase Plan
|
2014-12-31 |
| 2014-11-10 | 40569.99 | 未披露 | 定期报告 | 2014-11-03 |
| 2014-11-10 | 40546.90 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-11 | 40238.08 | 未披露 | 定期报告 | 2014-08-04 |
| 2014-08-11 | 39403.70 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-05-12 | 38861.52 | 未披露 | 定期报告 | 2014-05-05 |
| 2014-05-12 | 38693.49 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-04-11 | 38585.08 | 未披露 | 定期报告 | 2014-03-21 |
| 2014-03-03 | 37720.84 | 未披露 | 定期报告 | 2014-02-17 |
| 2014-03-03 | 36939.20 | 未披露 |
更多>>
From December 31,2012 to December 31,2013
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to debt conversions by Deerfield
Issuance of common stock pursuant to ATM issuances
Issuance of common shares pursuant to litigation settlement
Issuance of common shares under Employee Stock Purchase Plan
|
2013-12-31 |
| 2013-11-12 | 35731.27 | 未披露 | 定期报告 | 2013-11-04 |
| 2013-11-04 | 30999.33 | 未披露 | 定期报告 | 2013-09-30 |
| 2013-08-09 | 30177.42 | 未披露 | 定期报告 | 2013-08-02 |
| 2013-07-19 | 30088.72 | 未披露 | 定期报告 | 2013-07-01 |
| 2013-08-09 | 30086.97 | 未披露 | 定期报告 | 2013-06-30 |
| 2013-05-10 | 29088.23 | 未披露 | 定期报告 | 2013-05-03 |
| 2013-05-10 | 28937.53 | 未披露 | 定期报告 | 2013-03-31 |
| 2013-04-12 | 28936.13 | 未披露 | 定期报告 | 2013-03-25 |
| 2013-03-18 | 28935.01 | 未披露 | 定期报告 | 2013-03-13 |
| 2013-03-18 | 28603.51 | 未披露 |
更多>>
from DECEMBER 31, 2011 to DECEMBER 31, 2012
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to underwritten public offerings
Issuance of common shares in exchange for cancelling equal amounts of note payable to related party
Issuance of common shares pursuant to litigation settlement
Issuance of common shares under Employee Stock Purchase Plan
|
2012-12-31 |
| 2012-11-16 | 24577.74 | 未披露 | 定期报告 | 2012-11-07 |
| 2012-11-09 | 24577.71 | 未披露 | 定期报告 | 2012-11-05 |
| 2012-11-16 | 24957.16 | 未披露 | 定期报告 | 2012-10-31 |
| 2012-11-09 | 19976.75 | 未披露 | 定期报告 | 2012-09-30 |
| 2012-08-09 | 19938.41 | 未披露 | 定期报告 | 2012-08-06 |
| 2012-08-09 | 19930.08 | 未披露 | 定期报告 | 2012-06-30 |
| 2012-05-10 | 16782.20 | 未披露 | 定期报告 | 2012-04-27 |
| 2012-05-10 | 16781.58 | 未披露 | 定期报告 | 2012-03-31 |
| 2012-03-15 | 16746.59 | 未披露 | 定期报告 | 2012-03-02 |
| 2012-03-15 | 13152.29 | 未披露 |
更多>>
from DECEMBER 31, 2010 to DECEMBER 31, 2011
Issuance of common shares under Employee Stock Purchase Plan
Issuance of stock for cash
Issuance of stock in exchange for cancelling an equal amount of note payable to related party
Issuance of common shares from the release of restricted stock units
Exercise of stock options
|
2011-12-31 |
| 2011-11-04 | 13133.90 | 未披露 | 定期报告 | 2011-10-21 |
| 2011-11-04 | 13133.73 | 未披露 | 定期报告 | 2011-09-30 |
| 2011-08-04 | 13096.90 | 未披露 | 定期报告 | 2011-07-22 |
| 2011-08-04 | 13090.56 | 未披露 | 定期报告 | 2011-06-30 |
| 2011-05-10 | 13068.51 | 未披露 | 定期报告 | 2011-04-22 |
| 2011-05-10 | 13067.48 | 未披露 | 定期报告 | 2011-03-31 |
| 2011-03-16 | 13065.43 | 未披露 | 定期报告 | 2011-02-18 |
| 2011-03-16 | 12779.32 | 未披露 |
更多>>
from dec 31 2009 to dec 31 2010
Issuance of common shares under Employee Stock Purchase Plan
Issuance of stock for cash
Issuance of stock in exchange for cancelling an equal amount of note payable to related party
Issuance of stock under share lending agreement
Issuance of common shares from the release of restricted stock units
Exercise of stock options
|
2010-12-31 |
| 2010-10-29 | 12476.95 | 未披露 | 定期报告 | 2010-10-22 |
| 2010-10-29 | 12336.39 | 未披露 | 定期报告 | 2010-09-30 |
| 2010-08-02 | 11376.04 | 未披露 | 定期报告 | 2010-07-23 |
| 2010-08-02 | 11367.42 | 未披露 | 定期报告 | 2010-06-30 |
| 2010-04-30 | 11345.48 | 未披露 | 定期报告 | 2010-04-21 |
| 2010-04-30 | 11344.93 | 未披露 | 定期报告 | 2010-03-31 |
From JUNE 30, 2025 to SEPTEMBER 30, 2025
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase plan
From March 31, 2025 to June 30, 2025
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under employee stock purchase plan
Issuance of common stock from market price stock purchase plan
From JANUARY 1, 2025 to March 31, 2025
Net issuance of common stock associated with stock options and restricted stock units
From December 31, 2023 to December 31, 2024
Net issuance of common stock associated with restricted stock units and stock options
Issuance of common stock pursuant to conversion of Mann Group convertible note principal
Issuance of common stock pursuant to conversion of Mann Group convertible note interest
Issuance of common stock pursuant to conversion of senior convertible note principal
Issuance of common stock under employee stock purchase plan
Issuance of common stock from market price stock purchase plan
From June 30, 2024 to September 30, 2024
Net issuance of common stock associated with stock options and restricted stock units
From March 31, 2024 to June 30, 2024
Issuance of common stock pursuant to conversion of the Mann Group convertible note principal and interest
Issuance of common stock under employee stock purchase plan
Net issuance of common stock associated with stock options and restricted stock units
From January 1, 2024 to March 31, 2024
Issuance of common stock from market price stock purchase plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
From December 31, 2022 to December 31, 2023
Issuance of at-the-market offering
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from market price stock purchase plan
Net issuance of common stock associated with restricted stock units and stock options
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
From June 30, 2023 to September 30, 2023
Issuance of common stock associated at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
From March 31, 2023 to June 30, 2023
Issuance of common stock associated at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock under Employee Stock Purchase Plan
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase plan
From January 1, 2023 to March 31, 2023
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of at-the-market placement
Net issuance of common stock associated with stock options and restricted stock units
From December 31, 2021 to December 31,2022
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of at-the-market placement
Issuance of common stock from market price stock purchase plan
From JUNE 30, 2022 to SEPTEMBER 30, 2022
Issuance of at-the-market placement
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2022 to June 30, 2022
Issuance of common stock pursuant to conversion of Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
From JANUARY 1, 2022 to MARCH 31, 2022
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from market price stock purchase plan
From December 31, 2020 to December 31, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock pursuant to conversion of the 2024 convertible notes
Issuance of common stock pursuant to payoff of the 2024 convertible note interest
Issuance of at-the-market placement
Issuance of common stock from market price stock purchase
Issuance of common stock pursuant to a warrant conversion
From June 30, 2021 to September 30, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2021 to June 30, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock from market price stock purchase
From JANUARY 1, 2021 to MARCH 31, 2021
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of the Mann Group convertible note
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Issuance of common stock pursuant to conversion of the 2024 convertible notes
Issuance of common stock pursuant to payoff of the 2024 convertible note interest
Issuance of at-the-market placement
From December 31,2019 to December 31,2020
Payment of principal on senior convertible notes through common stock issuance
Payment of interest on senior convertible notes through common stock issuance
Issuance of common stock pursuant to conversion of Mann Group convertible note principal
Issuance of common stock pursuant to conversion of the Mann Group convertible note interest
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock from acquisition
Issuance of common stock from the exercise of warrants
Issuance of common stock from market price stock purchase
From June 30, 2020 to September 30, 2020
Issuance of common stock associated with debt interest payment
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock under Employee Stock Purchase Plan
From March 31, 2020 to June 30, 2020
Issuance of common stock from the exercise of warrants
Issuance of common stock pursuant to conversion of the June 2020 note
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at the market offering
Issuance of common stock from market price stock purchase
Adjustment of common stock in association with restricted stock units
from JANUARY 1, 2020 to March 31, 2020
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock associated with debt interest payment
Net issuance of common stock associated with stock options and restricted stock units
Issuance of common stock in at-the-market offering
from December 31, 2018 to DECEMBER 31, 2019
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of Deerfield Credit Facility
Issuance of common stock from the release of restricted stock units
Issuance of common stock pursuant to conversion of Mann Group promissory notes
Issuance of common stock pursuant to conversion of senior convertible notes
Issuance of common stock in at-the-market offering
Issuance of common stock from the exercise of warrants
From June 30, 2019 to September 30, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock pursuant to conversion of Senior Convertible Notes
Issuance of common stock pursuant to conversion of Facility Financing Obligation
Issuance of common stock pursuant to conversion of Promissory Notes
Issuance of common stock in at-the-market offering
From March 31, 2019 to June 30, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of at-the-market placement
from January 1, 2019 to March 31, 2019
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of shares pursuant to conversion of Senior Convertible Notes
from December 31, 2017 to DECEMBER 31, 2018
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of direct placement — common stock
Issuance of ATM placement
Issuance of shares pursuant to conversion of Note Payable to Related Party
Issuance of shares pursuant to conversion of Facility Financing Obligation
Issuance of shares pursuant to conversion of Senior Convertible Notes
Issuance of shares under Market Price Stock Purchase Plan
from December 31, 2016 to DECEMBER 31, 2017
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of shares pursuant to conversion of notes
Issuance of direct placement — common stock
Issuance of ATM placement
Reclassification of warrant liability to equity
from December 31, 2015 to March 3, 2017
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares under Employee Stock Purchase Plan
Issuance of direct placement — common stock and warrants
March 1, 2017, following stockholder approval of the Reverse Split Proposal, the Company’s board of directors approved a reverse stock split of the Company’s common stock at a ratio of 1-for-5. The Company’s common stock will begin trading on The NASDAQ Global Market on a split-adjusted basis when the market opens on March 3, 2017.
From December 31, 2014 to December 31, 2015
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to conversions of certain 2015 notes
Issuance of common stock for lender financing fees
Issuance of common stock pursuant to TASE stock sale
Return of loaned common stock
Issuance of common stock pursuant to at-the-market issuances
Issuance of common shares under Employee Stock Purchase Plan
From December 31,2013 to December 31,2014
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to debt conversions by Deerfield
Issuance of common shares under Employee Stock Purchase Plan
From December 31,2012 to December 31,2013
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to warrant exercises
Issuance of common shares pursuant to debt conversions by Deerfield
Issuance of common stock pursuant to ATM issuances
Issuance of common shares pursuant to litigation settlement
Issuance of common shares under Employee Stock Purchase Plan
from DECEMBER 31, 2011 to DECEMBER 31, 2012
Exercise of stock options
Issuance of common shares from the release of restricted stock units
Issuance of common shares pursuant to underwritten public offerings
Issuance of common shares in exchange for cancelling equal amounts of note payable to related party
Issuance of common shares pursuant to litigation settlement
Issuance of common shares under Employee Stock Purchase Plan
from DECEMBER 31, 2010 to DECEMBER 31, 2011
Issuance of common shares under Employee Stock Purchase Plan
Issuance of stock for cash
Issuance of stock in exchange for cancelling an equal amount of note payable to related party
Issuance of common shares from the release of restricted stock units
Exercise of stock options
from dec 31 2009 to dec 31 2010
Issuance of common shares under Employee Stock Purchase Plan
Issuance of stock for cash
Issuance of stock in exchange for cancelling an equal amount of note payable to related party
Issuance of stock under share lending agreement
Issuance of common shares from the release of restricted stock units
Exercise of stock options