股本结构
单位：万股
| 公告日期 | 2025-12-05 | 2025-11-13 | 2025-11-14 | 2025-08-13 | 2025-07-24 | 2025-07-24 |
|---|---|---|---|---|---|---|
| 证券总股本 | 499.96 | 499.88 | 499.85 | 499.07 | 500.00 | 12480.00 |
| 普通股本 | 499.96 | 499.88 | 499.85 | 499.07 | 500.00 | 12480.00 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-11-30 | 2025-11-10 | 2025-09-30 | 2025-08-08 | 2025-07-28 | 2025-07-24 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-12-05 | 499.96 | 未披露 | 定期报告 | 2025-11-30 |
| 2025-11-13 | 499.88 | 未披露 | 定期报告 | 2025-11-10 |
| 2025-11-14 | 499.85 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Vesting of restricted stock units and other stock awards
|
2025-09-30 |
| 2025-08-13 | 499.07 | 未披露 | 定期报告 | 2025-08-08 |
| 2025-07-24 | 500.00 | 未披露 |
更多>>
a 1-for-25 reverse stock split of the issued shares of the company's common stock
|
2025-07-28 |
| 2025-07-24 | 12480.00 | 未披露 | 定期报告 | 2025-07-24 |
| 2025-05-15 | 12463.13 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Vesting of restricted stock units and other stock awards
Exercise of pre-funded warrants in exchange for common stock
|
2025-03-31 |
| 2025-03-03 | 12463.13 | 未披露 | 定期报告 | 2025-02-26 |
| 2025-03-03 | 11564.99 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock from at-the-market transactions, net of issuance costs of $185
Retirement of common stock in exchange for pre-funded warrants
Sales of common stock pursuant to ESPP
Vesting of restricted stock units and other stock awards
Exercise of stock options
|
2024-12-31 |
| 2024-11-13 | 12353.29 | 未披露 | 定期报告 | 2024-11-08 |
| 2024-11-13 | 12286.67 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Vesting of restricted stock units
|
2024-09-30 |
| 2024-08-13 | 12267.51 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Vesting of restricted stock units and other stock awards
Exercise of stock options
Purchase of common stock under ESPP
|
2024-06-30 |
| 2024-04-26 | 12236.12 | 未披露 | 定期报告 | 2024-04-15 |
| 2024-05-09 | 12235.91 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock from at-the-market transactions, net of issuance costs of $185
Vesting of restricted stock units and other stock awards
|
2024-03-31 |
| 2024-05-09 | 12130.30 | 未披露 | 定期报告 | 2024-02-23 |
| 2024-02-28 | 12071.17 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Purchase of common stock under ESPP
Exercise of stock options
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,082
Vesting of restricted stock units and other stock awards
|
2023-12-31 |
| 2023-11-07 | 12058.21 | 未披露 | 定期报告 | 2023-11-03 |
| 2023-11-07 | 12054.90 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Vesting of restricted stock units and other stock awards
|
2023-09-30 |
| 2023-08-08 | 12050.73 | 未披露 | 定期报告 | 2023-08-04 |
| 2023-08-08 | 12045.92 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock from at-the-market transactions, net of issuance costs of $1,524
Exercise of stock options
Purchase of common stock under ESPP
Vesting of restricted stock units
|
2023-06-30 |
| 2023-05-09 | 11438.58 | 未披露 | 定期报告 | 2023-05-05 |
| 2023-04-28 | 10906.93 | 未披露 | 定期报告 | 2023-04-10 |
| 2023-05-09 | 10906.11 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Vesting of restricted stock units
Issuance of common stock from at-the-market transactions, net of issuance costs of $558
Exercise of stock options
|
2023-03-31 |
| 2023-02-28 | 10802.61 | 未披露 | 定期报告 | 2023-02-24 |
| 2023-02-28 | 10514.49 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Purchase of common stock under ESPP
Issuance of common stock from at-the-market transactions, net of issuance costs of $3,476
Exercise of common stock warrant
Vesting of restricted stock units
Exercise of stock options
|
2022-12-31 |
| 2022-11-07 | 9977.39 | 未披露 | 定期报告 | 2022-11-03 |
| 2022-11-07 | 9858.26 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of 251,000
Exercise of stock options
Vesting of restricted stock units
|
2022-09-30 |
| 2022-08-08 | 9716.93 | 未披露 | 定期报告 | 2022-08-04 |
| 2022-08-08 | 9716.64 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of $941,000
Exercise of common stock warrant
Vesting of restricted stock units
Purchase of common stock under ESPP
|
2022-06-30 |
| 2022-05-09 | 9699.13 | 未披露 | 定期报告 | 2022-05-05 |
| 2022-04-18 | 9446.90 | 未披露 | 定期报告 | 2022-04-14 |
| 2022-05-09 | 8707.31 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of $
Exercise of stock options
Vesting of restricted stock units
|
2022-03-31 |
| 2022-02-28 | 8338.98 | 未披露 | 定期报告 | 2022-02-25 |
| 2022-02-28 | 7370.91 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock from at-the-market transactions, net of issuance costs of $988,000
Exercise of stock options
Vesting of restricted stock units, net of employee tax obligation
Purchase of common stock under ESPP
|
2021-12-31 |
| 2021-11-09 | 7191.18 | 未披露 | 定期报告 | 2021-11-05 |
| 2021-11-09 | 7186.54 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Exercise of stock options
Vesting of restricted stock units
|
2021-09-30 |
| 2021-08-06 | 7176.15 | 未披露 | 定期报告 | 2021-08-04 |
| 2021-08-06 | 7140.12 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock from at-the-market transactions, net of issuance costs of $746
Exercise of stock options
Purchase of common stock under ESPP
|
2021-06-30 |
| 2021-05-10 | 6956.18 | 未披露 | 定期报告 | 2021-05-06 |
| 2021-05-10 | 6905.14 | 未披露 |
更多>>
From December 31, 2020 To March 31, 2021
Exercise of stock options
Vesting of restricted stock units, net of employee tax obligations
|
2021-03-31 |
| 2021-02-26 | 6904.29 | 未披露 | 定期报告 | 2021-02-23 |
| 2021-02-26 | 6884.13 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,176,000
Issuance of common stock under public offering, net of issuance costs of$10,809,000
Exercise of common stock warrant in exchange for common stock
Purchase of common stock under ESPP
Exercise of stock options
|
2020-12-31 |
| 2020-11-09 | 6849.74 | 未披露 | 定期报告 | 2020-11-04 |
| 2020-11-09 | 6847.01 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Exercise of stock options
|
2020-09-30 |
| 2020-08-07 | 6841.51 | 未披露 | 定期报告 | 2020-08-04 |
| 2020-08-07 | 6838.12 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,176
Issuance of common stock under public offering, net of issuance costs of $10,809
Purchase of common stock under ESPP
Exercise of stock options
|
2020-06-30 |
| 2020-06-02 | 6694.95 | 未披露 |
更多>>
1.Common stock offered by us 8,000,000 shares.
2.The number of shares of our common stock that will be outstanding immediately after this offering as shown above is based on 58,949,470 shares outstanding as of April 30, 2020
|
2020-06-02 |
| 2020-05-08 | 5894.95 | 未披露 | 定期报告 | 2020-04-30 |
| 2020-04-20 | 5894.23 | 未披露 | 定期报告 | 2020-04-15 |
| 2020-05-08 | 4800.60 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Exercise of common stock warrant in exchange for common stock
Exercise of stock options and warrants
|
2020-03-31 |
| 2020-02-28 | 4543.00 | 未披露 | 定期报告 | 2020-02-25 |
| 2020-02-28 | 4538.80 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common stock under public offering, net of issuance costs of $5,587
Exercise of stock options and warrants
Purchase of common stock under ESPP
Retirement of common stock in exchange for common stock warrant
|
2019-12-31 |
| 2019-11-06 | 4788.35 | 未披露 | 定期报告 | 2019-11-04 |
| 2019-11-06 | 4788.29 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Exercise of stock options and warrants
|
2019-09-30 |
| 2019-08-08 | 4781.00 | 未披露 | 定期报告 | 2019-08-07 |
| 2019-08-08 | 4779.91 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Exercise of stock options
Purchase of common stock under ESPP
|
2019-06-30 |
| 2019-05-09 | 4771.69 | 未披露 | 定期报告 | 2019-05-08 |
| 2019-05-09 | 4768.42 | 未披露 |
更多>>
from December 31, 2018 to March 31, 2019
Exercise of stock options
Issuance of common stock under public offering, net of issuance costs of $5,587
|
2019-03-31 |
| 2019-03-08 | 4768.42 | 未披露 | 定期报告 | 2019-03-07 |
| 2019-03-08 | 2323.45 | 未披露 |
更多>>
From December 31,2017 to December 31, 2018
Exercise of stock options
Purchase of common stock under ESPP
|
2018-12-31 |
| 2018-11-13 | 2318.25 | 未披露 | 定期报告 | 2018-11-12 |
| 2018-11-13 | 2316.09 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-14 | 2315.34 | 未披露 | 定期报告 | 2018-08-13 |
| 2018-08-14 | 2311.77 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-15 | 2290.19 | 未披露 | 定期报告 | 2018-05-10 |
| 2018-04-30 | 2289.59 | 未披露 | 定期报告 | 2018-04-30 |
| 2018-05-15 | 2287.00 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-03-28 | 2284.59 | 未披露 | 定期报告 | 2018-03-20 |
| 2018-03-28 | 2276.50 | 未披露 |
更多>>
from December 31, 2016 to December 31, 2017
Conversion of preferred stock into common stock
Issuance of common stock under Initial Public Offering, net of issuance costs of $7,580
Issuance of common stock under partial exercise of overallotment option, net of issuance costs of $55
Exercise of stock options and warrants
|
2017-12-31 |
| 2017-11-13 | 2275.34 | 未披露 | 定期报告 | 2017-11-08 |
| 2017-11-13 | 2273.43 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-11 | 2271.26 | 未披露 | 定期报告 | 2017-08-10 |
| 2017-06-29 | 2264.56 | 未披露 |
更多>>
1.Common stock offered by us 5,000,000 shares
2.The number of shares of common stock to be outstanding after this offering is based on 17,645,621 shares of common stock outstanding as of May 31, 2017
3.a one-for-4.5 reverse stock split of our common stock effected on June 15, 2017.
|
2017-06-28 |
| 2017-06-16 | 1764.56 | 未披露 |
更多>>
a one-for-4.5 reverse stock split of our common stock effected on June 15, 2017.
1,490,950 shares of our common stock
72,696,134 shares of our preferred stock that are convertible into 16,154,671 shares of our common stock
|
2017-06-15 |
| 2017-06-01 | 610.31 | 7269.61 |
更多>>
from December 31, 2016 to March 31, 2017
Exercise of stock options
|
2017-03-31 |
From June 30, 2025 to September 30, 2025
Vesting of restricted stock units and other stock awards
a 1-for-25 reverse stock split of the issued shares of the company's common stock
From December 31, 2024 to March 31, 2025
Vesting of restricted stock units and other stock awards
Exercise of pre-funded warrants in exchange for common stock
From December 31, 2023 to December 31, 2024
Issuance of common stock from at-the-market transactions, net of issuance costs of $185
Retirement of common stock in exchange for pre-funded warrants
Sales of common stock pursuant to ESPP
Vesting of restricted stock units and other stock awards
Exercise of stock options
From June 30, 2024 to September 30, 2024
Vesting of restricted stock units
From March 31, 2024 to June 30, 2024
Vesting of restricted stock units and other stock awards
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock from at-the-market transactions, net of issuance costs of $185
Vesting of restricted stock units and other stock awards
From December 31, 2022 to December 31, 2023
Purchase of common stock under ESPP
Exercise of stock options
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,082
Vesting of restricted stock units and other stock awards
From June 30, 2023 to September 30, 2023
Vesting of restricted stock units and other stock awards
From March 31, 2023 to June 30, 2023
Issuance of common stock from at-the-market transactions, net of issuance costs of $1,524
Exercise of stock options
Purchase of common stock under ESPP
Vesting of restricted stock units
From December 31, 2022 to March 31, 2023
Vesting of restricted stock units
Issuance of common stock from at-the-market transactions, net of issuance costs of $558
Exercise of stock options
From December 31, 2021 to December 31, 2022
Purchase of common stock under ESPP
Issuance of common stock from at-the-market transactions, net of issuance costs of $3,476
Exercise of common stock warrant
Vesting of restricted stock units
Exercise of stock options
From June 30, 2022 to September 30, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of 251,000
Exercise of stock options
Vesting of restricted stock units
From March 31, 2022 to June 30, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of $941,000
Exercise of common stock warrant
Vesting of restricted stock units
Purchase of common stock under ESPP
From December 31, 2021 to March 31, 2022
Issuance of common stock from at-the-market transactions, net of issuance costs of $
Exercise of stock options
Vesting of restricted stock units
From December 31, 2020 to December 31, 2021
Issuance of common stock from at-the-market transactions, net of issuance costs of $988,000
Exercise of stock options
Vesting of restricted stock units, net of employee tax obligation
Purchase of common stock under ESPP
From June 30, 2021 to September 30, 2021
Exercise of stock options
Vesting of restricted stock units
From March 31, 2021 to June 30, 2021
Issuance of common stock from at-the-market transactions, net of issuance costs of $746
Exercise of stock options
Purchase of common stock under ESPP
From December 31, 2020 To March 31, 2021
Exercise of stock options
Vesting of restricted stock units, net of employee tax obligations
From December 31,2019 to December 31,2020
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,176,000
Issuance of common stock under public offering, net of issuance costs of$10,809,000
Exercise of common stock warrant in exchange for common stock
Purchase of common stock under ESPP
Exercise of stock options
From June 30, 2020 to September 30, 2020
Exercise of stock options
From March 31, 2020 to June 30, 2020
Issuance of common stock from at-the-market transactions, net of issuance costs of $2,176
Issuance of common stock under public offering, net of issuance costs of $10,809
Purchase of common stock under ESPP
Exercise of stock options
1.Common stock offered by us 8,000,000 shares.
2.The number of shares of our common stock that will be outstanding immediately after this offering as shown above is based on 58,949,470 shares outstanding as of April 30, 2020
From December 31, 2019 to March 31, 2020
Exercise of common stock warrant in exchange for common stock
Exercise of stock options and warrants
from December 31, 2018 to December 31, 2019
Issuance of common stock under public offering, net of issuance costs of $5,587
Exercise of stock options and warrants
Purchase of common stock under ESPP
Retirement of common stock in exchange for common stock warrant
from June 30, 2019 to September 30, 2019
Exercise of stock options and warrants
From March 31, 2019 to June 30, 2019
Exercise of stock options
Purchase of common stock under ESPP
from December 31, 2018 to March 31, 2019
Exercise of stock options
Issuance of common stock under public offering, net of issuance costs of $5,587
From December 31,2017 to December 31, 2018
Exercise of stock options
Purchase of common stock under ESPP
from December 31, 2016 to December 31, 2017
Conversion of preferred stock into common stock
Issuance of common stock under Initial Public Offering, net of issuance costs of $7,580
Issuance of common stock under partial exercise of overallotment option, net of issuance costs of $55
Exercise of stock options and warrants
1.Common stock offered by us 5,000,000 shares
2.The number of shares of common stock to be outstanding after this offering is based on 17,645,621 shares of common stock outstanding as of May 31, 2017
3.a one-for-4.5 reverse stock split of our common stock effected on June 15, 2017.
a one-for-4.5 reverse stock split of our common stock effected on June 15, 2017.
1,490,950 shares of our common stock
72,696,134 shares of our preferred stock that are convertible into 16,154,671 shares of our common stock
from December 31, 2016 to March 31, 2017
Exercise of stock options