股本结构
单位：万股
| 公告日期 | 2024-04-04 | 2024-03-11 | 2023-11-02 | 2023-11-02 | 2023-08-03 | 2023-08-03 |
|---|---|---|---|---|---|---|
| 证券总股本 | 8346.24 | 8290.70 | 8271.55 | 8271.60 | 8271.55 | 8271.10 |
| 普通股本 | 8346.24 | 8290.70 | 8271.55 | 8271.60 | 8271.55 | 8271.10 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2024-03-01 | 2023-12-31 | 2023-10-30 | 2023-09-30 | 2023-07-31 | 2023-06-30 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2024-04-04 | 8346.24 | 未披露 | 定期报告 | 2024-03-01 |
| 2024-03-11 | 8290.70 | 未披露 |
更多>>
From December 31,2022 to December 31,2023
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
|
2023-12-31 |
| 2023-11-02 | 8271.55 | 未披露 | 定期报告 | 2023-10-30 |
| 2023-11-02 | 8271.60 | 未披露 | 定期报告 | 2023-09-30 |
| 2023-08-03 | 8271.55 | 未披露 | 定期报告 | 2023-07-31 |
| 2023-08-03 | 8271.10 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock to participants in 401(k) plan
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
|
2023-06-30 |
| 2023-05-04 | 8235.89 | 未披露 | 定期报告 | 2023-05-01 |
| 2023-03-29 | 8205.65 | 未披露 | 定期报告 | 2023-03-17 |
| 2023-02-28 | 8204.65 | 未披露 | 定期报告 | 2023-02-22 |
| 2023-02-28 | 8188.50 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
|
2022-12-31 |
| 2022-11-03 | 8172.61 | 未披露 | 定期报告 | 2022-10-31 |
| 2022-11-03 | 8171.40 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock upon exercise of stock options
|
2022-09-30 |
| 2022-08-04 | 8036.59 | 未披露 | 定期报告 | 2022-08-01 |
| 2022-08-04 | 7946.30 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
|
2022-06-30 |
| 2022-05-05 | 7925.71 | 未披露 | 定期报告 | 2022-05-02 |
| 2022-05-05 | 7808.70 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock upon exercise of stock options
|
2022-03-31 |
| 2022-04-06 | 7808.53 | 未披露 | 定期报告 | 2022-03-25 |
| 2022-03-01 | 7804.93 | 未披露 | 定期报告 | 2022-02-23 |
| 2022-03-01 | 7796.27 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock under offering, net of issuance costs
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock under Open Market Agreement, net of issuance costs
Issuance of common stock to participants in 401(k) plan
Vesting of common stock from early exercises
|
2021-12-31 |
| 2021-11-04 | 7770.91 | 未披露 | 定期报告 | 2021-11-01 |
| 2021-11-04 | 7764.26 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under Open Market Agreement, net of issuance costs
|
2021-09-30 |
| 2021-08-05 | 7733.81 | 未披露 | 定期报告 | 2021-08-02 |
| 2021-08-05 | 7730.72 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock to participants in 401(k) plan
|
2021-06-30 |
| 2021-05-06 | 7701.82 | 未披露 | 定期报告 | 2021-05-03 |
| 2021-04-28 | 7695.61 | 未披露 | 定期报告 | 2021-04-16 |
| 2021-05-06 | 7691.36 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of common stock under offering, net of issuance costs
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
|
2021-03-31 |
| 2021-03-15 | 7669.24 | 未披露 | 定期报告 | 2021-03-10 |
| 2021-01-08 | 7356.44 | 未披露 |
更多>>
1.Common stock offered by the company 4,629,630 shares of common stock.
2.The number of shares of common stock to be outstanding after this offering as stated above is based on 68,934,767 shares of common stock outstanding as of September 30, 2020.
|
2021-01-08 |
| 2021-03-15 | 7058.54 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under Open Market Agreement, net of issuance costs
Issuance of common stock in connection with employee stock purchase plan
Vesting of common stock from early exercises
Issuance of common stock to participants in 401(k) Plan
|
2020-12-31 |
| 2020-11-12 | 6901.93 | 未披露 | 定期报告 | 2020-11-09 |
| 2020-11-12 | 6893.48 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
|
2020-09-30 |
| 2020-08-12 | 6882.78 | 未披露 | 定期报告 | 2020-08-07 |
| 2020-08-12 | 6873.99 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock under 401(k) Plan
Vesting of common stock from early exercises
|
2020-06-30 |
| 2020-05-13 | 6814.19 | 未披露 | 定期报告 | 2020-05-07 |
| 2020-05-13 | 6793.64 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
|
2020-03-31 |
| 2020-04-08 | 6776.26 | 未披露 | 定期报告 | 2020-03-23 |
| 2020-03-17 | 6775.26 | 未披露 | 定期报告 | 2020-03-12 |
| 2020-03-17 | 6696.03 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Net exercise of preferred stock warrant to Series A preferred stock
Conversion of Series A, B, C, D, E convertible preferred stock to common stock concurrent with initial public offering
Issuance of common stock upon initial public offering, net of issuance cost
Issuance of common stock upon private placement
Issuance of common stock to participants in 401(k) Plan
Issuance of common stock upon exercise of stock options
Issuance of common stock in connection with employee stock purchase plan
Vesting of common stock from early exercises
|
2019-12-31 |
| 2019-11-12 | 6665.46 | 未披露 | 定期报告 | 2019-11-08 |
| 2019-11-12 | 6615.56 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
|
2019-09-30 |
| 2019-08-12 | 6604.30 | 未披露 | 定期报告 | 2019-08-09 |
| 2019-08-12 | 6603.93 | 未披露 |
更多>>
from March 31, 2019 to June 30,2019
Issuance of common stock upon initial public offering, net of issuance cost
Issuance of common stock upon private placement
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
Conversion of Series A, B, C, D, E convertible preferred stock to common stock
|
2019-06-30 |
| 2019-05-16 | 6602.19 | 未披露 | 定期报告 | 2019-05-10 |
| 2019-04-04 | 6499.37 | 未披露 |
更多>>
1. Common stock offered 6,666,667 shares
2. The number of shares of our common stock outstanding after the offering and the concurrent private placement to Merck is based on 54,205,356 shares of our common stock outstanding as of December 31, 2018
3. the one-for-two reverse stock split for our common stock and a proportional adjustment to the conversion ratio of our convertible preferred stock effected on March 22, 2019
|
2019-04-04 |
| 2019-05-16 | 702.67 | 4728.38 |
更多>>
from December 31, 2018 to March 31, 2019
Net exercise of preferred stock warrant to Series A preferred stock
Issuance of common stock to participants in 401(k) Plan
Vesting of common stock from early exercises
Exercise of stock options
|
2019-03-31 |
| 2018-09-28 | 1264.97 | 未披露 | 定期报告 | 2018-06-30 |
From December 31,2022 to December 31,2023
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
From March 31, 2023 to June 30, 2023
Issuance of common stock to participants in 401(k) plan
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
From December 31, 2021 to December 31, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
From June 30, 2022 to September 30, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock upon exercise of stock options
From March 31, 2022 to June 30, 2022
Issuance of common stock under Open Market Sale Agreement, net of issuance costs
Issuance of common stock under employee stock purchase plan
Issuance of common stock upon exercise of stock options
Issuance of common stock to participants in 401(k) plan
From December 31, 2021 to March 31, 2022
Issuance of common stock upon exercise of stock options
From December 31, 2020 to December 31, 2021
Issuance of common stock under offering, net of issuance costs
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock under Open Market Agreement, net of issuance costs
Issuance of common stock to participants in 401(k) plan
Vesting of common stock from early exercises
From June 30, 2021 to September 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under Open Market Agreement, net of issuance costs
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock to participants in 401(k) plan
From December 31, 2020 to March 31, 2021
Issuance of common stock under offering, net of issuance costs
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
1.Common stock offered by the company 4,629,630 shares of common stock.
2.The number of shares of common stock to be outstanding after this offering as stated above is based on 68,934,767 shares of common stock outstanding as of September 30, 2020.
From December 31, 2019 to December 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under Open Market Agreement, net of issuance costs
Issuance of common stock in connection with employee stock purchase plan
Vesting of common stock from early exercises
Issuance of common stock to participants in 401(k) Plan
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock in connection with employee stock purchase plan
Issuance of common stock under 401(k) Plan
Vesting of common stock from early exercises
From December 31, 2019 to March 31, 2020
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
from December 31, 2018 to December 31, 2019
Net exercise of preferred stock warrant to Series A preferred stock
Conversion of Series A, B, C, D, E convertible preferred stock to common stock concurrent with initial public offering
Issuance of common stock upon initial public offering, net of issuance cost
Issuance of common stock upon private placement
Issuance of common stock to participants in 401(k) Plan
Issuance of common stock upon exercise of stock options
Issuance of common stock in connection with employee stock purchase plan
Vesting of common stock from early exercises
from June 30, 2019 to September 30, 2019
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
from March 31, 2019 to June 30,2019
Issuance of common stock upon initial public offering, net of issuance cost
Issuance of common stock upon private placement
Issuance of common stock upon exercise of stock options
Vesting of common stock from early exercises
Conversion of Series A, B, C, D, E convertible preferred stock to common stock
1. Common stock offered 6,666,667 shares
2. The number of shares of our common stock outstanding after the offering and the concurrent private placement to Merck is based on 54,205,356 shares of our common stock outstanding as of December 31, 2018
3. the one-for-two reverse stock split for our common stock and a proportional adjustment to the conversion ratio of our convertible preferred stock effected on March 22, 2019
from December 31, 2018 to March 31, 2019
Net exercise of preferred stock warrant to Series A preferred stock
Issuance of common stock to participants in 401(k) Plan
Vesting of common stock from early exercises
Exercise of stock options