股本结构
单位：万股
| 公告日期 | 2022-07-26 | 2022-07-26 | 2022-04-28 | 2022-04-22 | 2022-04-28 | 2022-04-22 |
|---|---|---|---|---|---|---|
| 证券总股本 | 5368.89 | 5356.80 | 5347.37 | 5346.88 | 5321.00 | 5319.35 |
| 普通股本 | 5368.89 | 5356.80 | 5347.37 | 5346.88 | 5321.00 | 5319.35 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2022-07-18 | 2022-06-30 | 2022-04-22 | 2022-04-12 | 2022-03-31 | 2022-03-15 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2022-07-26 | 5368.89 | 未披露 | 定期报告 | 2022-07-18 |
| 2022-07-26 | 5356.80 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2022-06-30 |
| 2022-04-28 | 5347.37 | 未披露 | 定期报告 | 2022-04-22 |
| 2022-04-22 | 5346.88 | 未披露 | 定期报告 | 2022-04-12 |
| 2022-04-28 | 5321.00 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2022-03-31 |
| 2022-04-22 | 5319.35 | 未披露 | 定期报告 | 2022-03-15 |
| 2022-02-25 | 5312.82 | 未披露 | 定期报告 | 2022-02-18 |
| 2022-02-25 | 5311.30 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2021-12-31 |
| 2021-12-23 | 5310.59 | 未披露 | 定期报告 | 2021-12-22 |
| 2021-11-04 | 5269.54 | 未披露 | 定期报告 | 2021-10-28 |
| 2021-11-04 | 5265.90 | 未披露 |
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From June 30, 2021 to September 30, 2021
Issuance of common stock upon exercise of stock options
Tax withholding related to vesting of restricted stock units
Issuance of common stock for vested restricted stock units
|
2021-09-30 |
| 2021-08-03 | 5218.54 | 未披露 | 定期报告 | 2021-07-27 |
| 2021-08-03 | 5208.00 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2021-06-30 |
| 2021-04-29 | 5132.97 | 未披露 | 定期报告 | 2021-04-23 |
| 2021-04-16 | 5129.06 | 未披露 | 定期报告 | 2021-04-09 |
| 2021-04-29 | 5100.90 | 未披露 |
更多>>
from December 31, 2020 to March 31, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2021-03-31 |
| 2021-02-25 | 5078.20 | 未披露 | 定期报告 | 2021-02-19 |
| 2021-04-16 | 5077.45 | 未披露 | 定期报告 | 2021-02-15 |
| 2021-02-25 | 5045.70 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2020-12-31 |
| 2020-11-02 | 5014.65 | 未披露 | 定期报告 | 2020-10-27 |
| 2020-11-02 | 5013.80 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2020-09-30 |
| 2020-08-05 | 4956.54 | 未披露 | 定期报告 | 2020-07-29 |
| 2020-08-05 | 4954.70 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2020-06-30 |
| 2020-05-07 | 4875.60 | 未披露 | 定期报告 | 2020-04-30 |
| 2020-04-23 | 4866.24 | 未披露 | 定期报告 | 2020-04-09 |
| 2020-05-07 | 4866.20 | 未披露 |
更多>>
from December 31, 2019 to March 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2020-03-31 |
| 2020-04-23 | 4864.22 | 未披露 | 定期报告 | 2020-02-29 |
| 2020-02-28 | 4863.65 | 未披露 | 定期报告 | 2020-02-21 |
| 2020-02-28 | 4852.60 | 未披露 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of common stock in exchange for research and development services
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
Issuance of common stock in exchange for research and development services, net of issuance costs of $46
|
2019-12-31 |
| 2019-11-04 | 4824.11 | 未披露 | 定期报告 | 2019-10-31 |
| 2019-11-04 | 4801.70 | 未披露 |
更多>>
From June 30, 2019 to September 30, 2019
Issuance of common stock in exchange for research and development services
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2019-09-30 |
| 2019-08-07 | 4740.77 | 未披露 | 定期报告 | 2019-07-31 |
| 2019-08-07 | 4715.20 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2019-06-30 |
| 2019-05-07 | 4647.43 | 未披露 | 定期报告 | 2019-04-30 |
| 2019-04-22 | 4646.95 | 未披露 | 定期报告 | 2019-04-10 |
| 2019-05-07 | 4645.50 | 未披露 |
更多>>
from December 31,2018 to March 31, 2019
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2019-03-31 |
| 2019-03-08 | 4642.67 | 未披露 | 定期报告 | 2019-02-28 |
| 2019-03-08 | 4637.80 | 未披露 |
更多>>
from December 31,2017 to December 31,2018
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2018-12-31 |
| 2018-11-05 | 4604.93 | 未披露 | 定期报告 | 2018-10-31 |
| 2018-11-05 | 4584.00 | 未披露 | 定期报告 | 2018-09-30 |
| 2018-08-06 | 4530.25 | 未披露 | 定期报告 | 2018-07-31 |
| 2018-08-06 | 4490.60 | 未披露 | 定期报告 | 2018-06-30 |
| 2018-05-09 | 4455.88 | 未披露 | 定期报告 | 2018-04-30 |
| 2018-04-19 | 4431.96 | 未披露 | 定期报告 | 2018-04-06 |
| 2018-05-09 | 4431.40 | 未披露 | 定期报告 | 2018-03-31 |
| 2018-03-09 | 4427.84 | 未披露 | 定期报告 | 2018-02-28 |
| 2018-03-09 | 4421.90 | 未披露 |
更多>>
from December 31, 2016 to December 31, 2017
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2017-12-31 |
| 2017-11-08 | 4394.53 | 未披露 | 定期报告 | 2017-10-31 |
| 2017-11-08 | 4390.90 | 未披露 | 定期报告 | 2017-09-30 |
| 2017-08-09 | 4363.88 | 未披露 | 定期报告 | 2017-07-31 |
| 2017-08-09 | 4356.80 | 未披露 | 定期报告 | 2017-06-30 |
| 2017-04-17 | 4267.08 | 未披露 | 定期报告 | 2017-04-05 |
| 2017-05-09 | 4266.40 | 未披露 | 定期报告 | 2017-03-31 |
| 2017-03-16 | 4264.15 | 未披露 | 定期报告 | 2017-02-28 |
| 2017-03-16 | 4252.60 | 未披露 |
更多>>
from December 31, 2015 to December 31, 2016
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2016-12-31 |
| 2016-11-08 | 4232.40 | 未披露 | 定期报告 | 2016-10-31 |
| 2016-11-08 | 4231.50 | 未披露 | 定期报告 | 2016-09-30 |
| 2016-08-09 | 4181.51 | 未披露 | 定期报告 | 2016-07-31 |
| 2016-08-09 | 4175.30 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-04-26 | 4135.23 | 未披露 | 定期报告 | 2016-04-11 |
| 2016-05-10 | 4134.00 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-03-15 | 4110.03 | 未披露 | 定期报告 | 2016-02-29 |
| 2016-03-15 | 4098.60 | 未披露 |
更多>>
From December 31, 2014 to December 31, 2015
Issuance of common stock from public stock offering, net of discount and offering costs
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2015-12-31 |
| 2015-11-06 | 4052.33 | 未披露 | 定期报告 | 2015-10-31 |
| 2015-11-06 | 4047.80 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-10 | 4045.67 | 未披露 | 定期报告 | 2015-07-31 |
| 2015-08-10 | 4014.50 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-06-01 | 3323.68 | 未披露 | 定期报告 | 2015-05-26 |
| 2015-05-11 | 3290.05 | 未披露 | 定期报告 | 2015-04-30 |
| 2015-05-11 | 3289.70 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-03-16 | 3278.63 | 未披露 | 定期报告 | 2015-02-28 |
| 2015-03-16 | 3275.20 | 未披露 |
更多>>
from December 31, 2013 to December 31, 2014
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
|
2014-12-31 |
| 2014-12-19 | 3252.27 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-08 | 3255.10 | 未披露 | 定期报告 | 2014-07-31 |
| 2014-08-08 | 3215.10 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-06-04 | 3178.08 | 未披露 | 定期报告 | 2014-05-27 |
| 2014-06-24 | 3166.40 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-06-04 | 3157.16 | 未披露 |
更多>>
from December 31, 2012 to December 31, 2013
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
|
2013-12-31 |
| 2014-04-09 | 3130.49 | 未披露 | 定期报告 | 2013-09-30 |
| 2013-08-08 | 3125.57 | 未披露 | 定期报告 | 2013-07-31 |
| 2013-08-08 | 3097.13 | 未披露 | 定期报告 | 2013-06-30 |
| 2013-05-15 | 3061.14 | 未披露 | 定期报告 | 2013-04-30 |
| 2013-04-26 | 3061.09 | 未披露 | 定期报告 | 2013-04-17 |
| 2013-05-15 | 3060.43 | 未披露 | 定期报告 | 2013-03-31 |
| 2013-03-15 | 3058.95 | 未披露 | 定期报告 | 2013-02-28 |
| 2013-03-15 | 3054.62 | 未披露 |
更多>>
from December 31, 2011 to December 31, 2012
Issuance of common stock for investment
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
|
2012-12-31 |
| 2012-11-09 | 3027.78 | 未披露 | 定期报告 | 2012-09-30 |
| 2012-08-10 | 3013.76 | 未披露 | 定期报告 | 2012-07-31 |
| 2012-08-10 | 3013.73 | 未披露 | 定期报告 | 2012-06-30 |
| 2012-05-10 | 2984.99 | 未披露 | 定期报告 | 2012-04-30 |
| 2012-05-10 | 2487.70 | 未披露 | 定期报告 | 2012-03-31 |
| 2012-03-30 | 2487.32 | 未披露 | 定期报告 | 2012-02-29 |
| 2012-03-30 | 2486.26 | 未披露 |
更多>>
from December 31, 2010 to December 31, 2011
Conversion of preferred stock into shares of common stock
Issuance of common stock upon initial public offering at $11.00 per share, net of issuance costs of $4,263
Issuance of common stock upon exercise of stock options
Repurchase of common stock
Issuance of common stock under employee stock purchase plan
|
2011-12-31 |
| 2011-11-10 | 2475.43 | 未披露 | 定期报告 | 2011-11-02 |
| 2011-11-10 | 2475.17 | 未披露 | 定期报告 | 2011-09-30 |
| 2011-08-11 | 2474.54 | 未披露 | 定期报告 | 2011-08-02 |
| 2011-08-11 | 2473.89 | 未披露 | 定期报告 | 2011-06-30 |
| 2011-05-12 | 2465.51 | 未披露 | 定期报告 | 2011-05-02 |
| 2011-05-12 | 2464.76 | 未披露 | 定期报告 | 2011-03-31 |
| 2011-03-28 | 2462.60 | 未披露 | 定期报告 | 2011-02-28 |
| 2011-03-28 | 195.53 | 665.80 |
更多>>
from December 31, 2009 to December 31, 2010
Issuance of Series X preferred stock for cash, net of issuance costs of $24
Exercise of stock options
Exercise of warrants
Repurchases of common stock
|
2010-12-31 |
From March 31, 2022 to June 30, 2022
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From December 31, 2021 to March 31, 2022
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From December 31, 2020 to December 31, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From June 30, 2021 to September 30, 2021
Issuance of common stock upon exercise of stock options
Tax withholding related to vesting of restricted stock units
Issuance of common stock for vested restricted stock units
From March 31, 2021 to June 30, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2020 to March 31, 2021
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From December 31, 2019 to December 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From June 30, 2020 to September 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From March 31, 2020 to June 30, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2019 to March 31, 2020
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2018 to December 31, 2019
Issuance of common stock in exchange for research and development services
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
Issuance of common stock in exchange for research and development services, net of issuance costs of $46
From June 30, 2019 to September 30, 2019
Issuance of common stock in exchange for research and development services
Issuance of common stock upon exercise of stock options
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From March 31, 2019 to June 30, 2019
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31,2018 to March 31, 2019
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31,2017 to December 31,2018
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2016 to December 31, 2017
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2015 to December 31, 2016
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
From December 31, 2014 to December 31, 2015
Issuance of common stock from public stock offering, net of discount and offering costs
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2013 to December 31, 2014
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
Tax withholding related to vesting of restricted stock units
from December 31, 2012 to December 31, 2013
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
Issuance of common stock for vested restricted stock units
from December 31, 2011 to December 31, 2012
Issuance of common stock for investment
Issuance of common stock upon exercise of stock options
Issuance of common stock under employee stock purchase plan
from December 31, 2010 to December 31, 2011
Conversion of preferred stock into shares of common stock
Issuance of common stock upon initial public offering at $11.00 per share, net of issuance costs of $4,263
Issuance of common stock upon exercise of stock options
Repurchase of common stock
Issuance of common stock under employee stock purchase plan
from December 31, 2009 to December 31, 2010
Issuance of Series X preferred stock for cash, net of issuance costs of $24
Exercise of stock options
Exercise of warrants
Repurchases of common stock