股本结构
单位：万股
| 公告日期 | 2026-05-06 | 2026-04-24 | 2026-05-06 | 2026-03-02 | 2026-03-02 | 2025-11-10 |
|---|---|---|---|---|---|---|
| 证券总股本 | 4710.60 | 4706.50 | 4706.10 | 4694.00 | 4674.40 | 4671.08 |
| 普通股本 | 4710.60 | 4706.50 | 4706.10 | 4694.00 | 4674.40 | 4671.08 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-04-30 | 2026-04-14 | 2026-03-31 | 2026-02-24 | 2025-12-31 | 2025-11-04 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-05-06 | 4710.60 | 未披露 | 定期报告 | 2026-04-30 |
| 2026-04-24 | 4706.50 | 未披露 | 定期报告 | 2026-04-14 |
| 2026-05-06 | 4706.10 | 未披露 |
更多>>
From December 31, 2025 to March 31, 2026
Issuance of common stock under stock plans, net of tax and payments
|
2026-03-31 |
| 2026-03-02 | 4694.00 | 未披露 | 定期报告 | 2026-02-24 |
| 2026-03-02 | 4674.40 | 未披露 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of common stock under stock plans, including tax effects
Common stock issued as consideration in business combinations, net of tax
|
2025-12-31 |
| 2025-11-10 | 4671.08 | 未披露 | 定期报告 | 2025-11-04 |
| 2025-11-10 | 4668.30 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Common stock issued as consideration in business combinations, net of tax
Issuance of common stock under stock plans, net of tax and payments
|
2025-09-30 |
| 2025-08-07 | 4646.59 | 未披露 | 定期报告 | 2025-07-31 |
| 2025-07-08 | 4665.49 | 未披露 | 定期报告 | 2025-07-08 |
| 2025-08-07 | 3887.30 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock under stock plans, net of tax and payments
|
2025-06-30 |
| 2025-06-16 | 3885.49 | 未披露 | 定期报告 | 2025-06-05 |
| 2025-05-12 | 3882.94 | 未披露 | 定期报告 | 2025-05-06 |
| 2025-04-30 | 3882.11 | 未披露 | 定期报告 | 2025-04-23 |
| 2025-05-12 | 3880.10 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock under stock plans, net of tax and payments
|
2025-03-31 |
| 2025-04-04 | 3878.90 | 未披露 | 定期报告 | 2025-03-25 |
| 2025-03-17 | 3877.62 | 未披露 | 定期报告 | 2025-03-11 |
| 2025-04-04 | 3866.63 | 未披露 | 定期报告 | 2025-03-01 |
| 2025-06-16 | 3856.99 | 未披露 | 定期报告 | 2025-01-06 |
| 2025-03-17 | 3854.40 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock under stock plans, including tax effects
|
2024-12-31 |
| 2024-12-26 | 3852.43 | 未披露 | 定期报告 | 2024-12-17 |
| 2024-12-26 | 3847.50 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock under stock plans, net of tax effects and payments
|
2024-09-30 |
| 2024-08-08 | 3837.90 | 未披露 | 定期报告 | 2024-08-02 |
| 2024-08-08 | 3839.80 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock under stock plans, net of tax effects and payments
|
2024-06-30 |
| 2024-05-08 | 3827.01 | 未披露 | 定期报告 | 2024-05-02 |
| 2024-04-15 | 3824.71 | 未披露 | 定期报告 | 2024-04-05 |
| 2024-05-08 | 3835.30 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock under stock plans, including tax effects
|
2024-03-31 |
| 2024-04-15 | 3812.16 | 未披露 | 定期报告 | 2024-03-01 |
| 2024-02-29 | 3806.36 | 未披露 | 定期报告 | 2024-02-26 |
| 2024-02-29 | 3801.40 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock under stock plans, including tax effects
|
2023-12-31 |
| 2023-11-08 | 3782.97 | 未披露 | 定期报告 | 2023-11-02 |
| 2023-11-08 | 3783.90 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock under stock plans, including tax effects
|
2023-09-30 |
| 2023-08-08 | 3755.26 | 未披露 | 定期报告 | 2023-08-02 |
| 2023-05-09 | 3740.87 | 未披露 | 定期报告 | 2023-05-01 |
| 2023-04-14 | 3738.23 | 未披露 | 定期报告 | 2023-04-10 |
| 2023-05-09 | 3742.40 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
|
2023-03-31 |
| 2023-03-06 | 3724.86 | 未披露 | 定期报告 | 2023-02-28 |
| 2023-03-06 | 3728.00 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
|
2022-12-31 |
| 2022-11-09 | 3705.47 | 未披露 | 定期报告 | 2022-11-01 |
| 2022-11-09 | 3709.36 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of capital shares:
Issuance of common stock
Restricted units converted
ESPP stock purchase
Exercised stock options
|
2022-09-30 |
| 2022-08-08 | 3698.76 | 未披露 | 定期报告 | 2022-08-01 |
| 2022-08-08 | 3697.48 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of capital shares:
Exercised stock options
Restricted units converted
Issuance of common stock
|
2022-06-30 |
| 2022-05-10 | 3691.01 | 未披露 | 定期报告 | 2022-05-04 |
| 2022-04-29 | 3689.92 | 未披露 | 定期报告 | 2022-04-28 |
| 2022-04-29 | 3889.78 | 未披露 | 定期报告 | 2022-04-15 |
| 2022-05-10 | 3689.92 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
|
2022-03-31 |
| 2022-03-01 | 3684.73 | 未披露 | 定期报告 | 2022-02-23 |
| 2022-03-01 | 3676.80 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Issuance of common stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
|
2021-12-31 |
| 2021-11-04 | 3664.80 | 未披露 | 定期报告 | 2021-11-01 |
| 2021-11-04 | 3657.41 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
|
2021-09-30 |
| 2021-08-05 | 3652.28 | 未披露 | 定期报告 | 2021-07-29 |
| 2021-08-05 | 3645.44 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Exercise of common stock options and vesting of restricted stock
|
2021-06-30 |
| 2021-05-06 | 3633.66 | 未披露 | 定期报告 | 2021-04-30 |
| 2021-04-29 | 3633.48 | 未披露 | 定期报告 | 2021-04-26 |
| 2021-04-29 | 3633.38 | 未披露 | 定期报告 | 2021-04-15 |
| 2021-05-06 | 3629.49 | 未披露 |
更多>>
From December 31, 2020 To March 31, 2021
Exercise of common stock option and warrants and vesting of restricted stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
|
2021-03-31 |
| 2021-03-05 | 3626.76 | 未披露 | 定期报告 | 2021-03-01 |
| 2021-02-08 | 3540.78 | 未披露 |
更多>>
1.Common stock offered by the company pursuant to this prospectus supplement 3,571,428 shares.
2.The number of shares of common stock to be outstanding immediately after this offering is based on an aggregate of 31,836,339 shares of common stock outstanding as of December 31, 2020.
|
2021-02-08 |
| 2021-03-05 | 3179.65 | 未披露 |
更多>>
From December 31, 2019 to December 31, 2020
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
|
2020-12-31 |
| 2020-11-06 | 3166.82 | 未披露 | 定期报告 | 2020-10-30 |
| 2020-11-06 | 3158.35 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering,net
ESPP stock purchase
|
2020-09-30 |
| 2020-08-11 | 3103.24 | 未披露 |
更多>>
1.Common stock offered by the company pursuant to this prospectus supplement 2,651,108 shares.
2.The number of shares of common stock to be outstanding immediately after this offering is based on an aggregate of 28,381,280 shares of common stock outstanding as of June 30, 2020.
|
2020-08-11 |
| 2020-08-05 | 2844.03 | 未披露 | 定期报告 | 2020-07-30 |
| 2020-08-05 | 2838.13 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Exercise of common stock options and vesting of restricted stock
|
2020-06-30 |
| 2020-05-07 | 2831.10 | 未披露 | 定期报告 | 2020-05-01 |
| 2020-04-29 | 2830.69 | 未披露 | 定期报告 | 2020-04-28 |
| 2020-04-28 | 2828.68 | 未披露 | 定期报告 | 2020-04-01 |
| 2020-05-07 | 2824.34 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
|
2020-03-31 |
| 2020-03-13 | 2822.57 | 未披露 | 定期报告 | 2020-03-01 |
| 2020-03-13 | 2811.22 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Sale of common stock in "at-the-market" offering, net
Sale of common stock in underwritten public offering, net
Issuance of shares for the acquisition of Umandiagnostics AB
Employee stock purchase plan
|
2019-12-31 |
| 2019-11-08 | 2801.48 | 未披露 | 定期报告 | 2019-10-31 |
| 2019-11-08 | 2796.77 | 未披露 |
更多>>
From June 30, 2019 to September 30, 2019
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering, net
Issuance of shares for acquisition of Uman
ESPP stock purchase
|
2019-09-30 |
| 2019-08-13 | 2727.03 | 未披露 | 定期报告 | 2019-08-13 |
| 2019-08-06 | 2516.51 | 未披露 | 定期报告 | 2019-07-31 |
| 2019-08-06 | 2489.40 | 未披露 |
更多>>
From March 31, 2019 to June 30, 2019
Exercise of common stock options and vesting of restricted stock
Sale of common stock in at-the-market offering
|
2019-06-30 |
| 2019-06-06 | 2489.63 | 未披露 | 定期报告 | 2019-06-03 |
| 2019-06-06 | 2260.82 | 未披露 | 定期报告 | 2019-05-15 |
| 2019-05-10 | 2259.61 | 未披露 | 定期报告 | 2019-05-08 |
| 2019-04-30 | 2253.10 | 未披露 | 定期报告 | 2019-04-01 |
| 2019-05-10 | 2249.14 | 未披露 |
更多>>
From December 31, 2018 to March 31, 2019
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
|
2019-03-31 |
| 2019-03-18 | 2246.12 | 未披露 | 定期报告 | 2019-03-01 |
| 2019-03-18 | 2236.90 | 未披露 |
更多>>
From December 31, 2017 to December 31, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
|
2018-12-31 |
| 2018-11-07 | 2219.78 | 未披露 | 定期报告 | 2018-11-01 |
| 2018-11-07 | 2215.14 | 未披露 |
更多>>
From December 31, 2017 to September 30, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
|
2018-09-30 |
| 2018-08-10 | 2209.96 | 未披露 | 定期报告 | 2018-08-01 |
| 2018-08-10 | 2198.07 | 未披露 |
更多>>
From December 31, 2017 to June 30, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
|
2018-06-30 |
| 2018-05-15 | 2196.01 | 未披露 | 定期报告 | 2018-05-01 |
| 2018-04-30 | 2195.80 | 未披露 | 定期报告 | 2018-04-20 |
| 2018-05-15 | 2182.33 | 未披露 |
更多>>
From December 31, 2017 to March 31, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
|
2018-03-31 |
| 2018-03-19 | 2193.75 | 未披露 | 定期报告 | 2018-03-01 |
| 2018-03-19 | 2170.70 | 未披露 |
更多>>
from December 31, 2016 to December 31, 2017
Exercise of preferred stock warrants
Conversion of preferred stock into common stock
Issuance of Series D-1 preferred stock, net of issuance costs
Exercise of common stock options and vesting of restricted stock
Issuance of common stock in initial public offering, net of $8,173 in offering costs
|
2017-12-31 |
| 2017-12-07 | 2117.96 | 未披露 |
更多>>
1.Common stock offered 4,275,200 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 16,904,360 shares of our common stock outstanding as of October 31, 2017
3.a 1-for-3.214 reverse stock split of our common stock effected on December 4, 2017
|
2017-12-07 |
| 2017-11-27 | 1690.44 | 未披露 | 定期报告 | 2017-10-31 |
From December 31, 2025 to March 31, 2026
Issuance of common stock under stock plans, net of tax and payments
From December 31, 2024 to December 31, 2025
Issuance of common stock under stock plans, including tax effects
Common stock issued as consideration in business combinations, net of tax
From June 30, 2025 to September 30, 2025
Common stock issued as consideration in business combinations, net of tax
Issuance of common stock under stock plans, net of tax and payments
From March 31, 2025 to June 30, 2025
Issuance of common stock under stock plans, net of tax and payments
From December 31, 2024 to March 31, 2025
Issuance of common stock under stock plans, net of tax and payments
From December 31, 2023 to December 31, 2024
Issuance of common stock under stock plans, including tax effects
From June 30, 2024 to September 30, 2024
Issuance of common stock under stock plans, net of tax effects and payments
From March 31, 2024 to June 30, 2024
Issuance of common stock under stock plans, net of tax effects and payments
From December 31, 2023 to March 31, 2024
Issuance of common stock under stock plans, including tax effects
From December 31, 2022 to December 31, 2023
Issuance of common stock under stock plans, including tax effects
From June 30, 2023 to September 30, 2023
Issuance of common stock under stock plans, including tax effects
From December 31, 2022 to March 31, 2023
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
From December 31, 2021 to December 31, 2022
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
From June 30, 2022 to September 30, 2022
Issuance of capital shares:
Issuance of common stock
Restricted units converted
ESPP stock purchase
Exercised stock options
From March 31, 2022 to June 30, 2022
Issuance of capital shares:
Exercised stock options
Restricted units converted
Issuance of common stock
From December 31, 2021 to March 31, 2022
Exercised stock options
Restricted units converted
ESPP stock purchase
Issuance of common stock
From December 31, 2020 to December 31, 2021
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Issuance of common stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
From June 30, 2021 to September 30, 2021
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
From March 31, 2021 to June 30, 2021
Exercise of common stock options and vesting of restricted stock
From December 31, 2020 To March 31, 2021
Exercise of common stock option and warrants and vesting of restricted stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
1.Common stock offered by the company pursuant to this prospectus supplement 3,571,428 shares.
2.The number of shares of common stock to be outstanding immediately after this offering is based on an aggregate of 31,836,339 shares of common stock outstanding as of December 31, 2020.
From December 31, 2019 to December 31, 2020
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering, net
ESPP stock purchase
From June 30, 2020 to September 30, 2020
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering,net
ESPP stock purchase
1.Common stock offered by the company pursuant to this prospectus supplement 2,651,108 shares.
2.The number of shares of common stock to be outstanding immediately after this offering is based on an aggregate of 28,381,280 shares of common stock outstanding as of June 30, 2020.
From March 31, 2020 to June 30, 2020
Exercise of common stock options and vesting of restricted stock
From December 31, 2019 to March 31, 2020
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
From December 31, 2018 to December 31, 2019
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Sale of common stock in "at-the-market" offering, net
Sale of common stock in underwritten public offering, net
Issuance of shares for the acquisition of Umandiagnostics AB
Employee stock purchase plan
From June 30, 2019 to September 30, 2019
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
Sale of common stock in underwritten public offering, net
Issuance of shares for acquisition of Uman
ESPP stock purchase
From March 31, 2019 to June 30, 2019
Exercise of common stock options and vesting of restricted stock
Sale of common stock in at-the-market offering
From December 31, 2018 to March 31, 2019
Exercise of common stock options and vesting of restricted stock
ESPP stock purchase
From December 31, 2017 to December 31, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
From December 31, 2017 to September 30, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
From December 31, 2017 to June 30, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
From December 31, 2017 to March 31, 2018
Exercise of common stock warrants
Exercise of common stock options and vesting of restricted stock
from December 31, 2016 to December 31, 2017
Exercise of preferred stock warrants
Conversion of preferred stock into common stock
Issuance of Series D-1 preferred stock, net of issuance costs
Exercise of common stock options and vesting of restricted stock
Issuance of common stock in initial public offering, net of $8,173 in offering costs
1.Common stock offered 4,275,200 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 16,904,360 shares of our common stock outstanding as of October 31, 2017
3.a 1-for-3.214 reverse stock split of our common stock effected on December 4, 2017