股本结构
单位：万股
| 公告日期 | 2016-08-04 | 2016-08-04 | 2016-04-29 | 2016-05-05 | 2016-02-26 | 2016-02-26 |
|---|---|---|---|---|---|---|
| 证券总股本 | 8530.68 | 8553.10 | 8530.68 | 8528.93 | 8524.39 | 8523.56 |
| 普通股本 | 8530.68 | 8553.10 | 8530.68 | 8528.93 | 8524.39 | 8523.56 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2016-08-02 | 2016-06-30 | 2016-04-25 | 2016-03-31 | 2016-02-22 | 2015-12-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2016-08-04 | 8530.68 | 未披露 | 定期报告 | 2016-08-02 |
| 2016-08-04 | 8553.10 | 未披露 | 定期报告 | 2016-06-30 |
| 2016-04-29 | 8530.68 | 未披露 | 定期报告 | 2016-04-25 |
| 2016-05-05 | 8528.93 | 未披露 | 定期报告 | 2016-03-31 |
| 2016-02-26 | 8524.39 | 未披露 | 定期报告 | 2016-02-22 |
| 2016-02-26 | 8523.56 | 未披露 |
更多>>
from December 31, 2014 to December 31, 2015
Issuance of common stock:Employee stock purchase plan
Issuance of common stock:Sale of common stock
Issuance of common stock:Restricted stock units
Exercise of common stock options
Exercise of common stock warrants
Common stock issued for QUINSAIR acquisition
|
2015-12-31 |
| 2015-11-05 | 8510.12 | 未披露 | 定期报告 | 2015-11-04 |
| 2015-11-05 | 8157.84 | 未披露 | 定期报告 | 2015-09-30 |
| 2015-08-06 | 8118.00 | 未披露 | 定期报告 | 2015-08-04 |
| 2015-08-06 | 8103.21 | 未披露 | 定期报告 | 2015-06-30 |
| 2015-05-07 | 8048.03 | 未披露 |
更多>>
In April 2015, we completed a public offering of 10.925 million shares of our common stock for net proceeds of $92 million.
|
2015-05-05 |
| 2015-05-07 | 6939.48 | 未披露 | 定期报告 | 2015-03-31 |
| 2015-03-26 | 6922.79 | 未披露 | 定期报告 | 2015-03-10 |
| 2015-03-02 | 6914.45 | 未披露 | 定期报告 | 2015-02-27 |
| 2015-03-02 | 6886.14 | 未披露 |
更多>>
from December 31, 2013 to December 31, 2014
Issuance of common stock:Employee stock purchase plan
Issuance of common stock:At-the-market financing facility, net of offering costs
Exercise of common stock options
Exercise of common stock warrants
|
2014-12-31 |
| 2014-11-06 | 6356.37 | 未披露 | 定期报告 | 2014-11-04 |
| 2014-11-06 | 6326.85 | 未披露 | 定期报告 | 2014-09-30 |
| 2014-08-07 | 6274.29 | 未披露 | 定期报告 | 2014-08-04 |
| 2014-08-07 | 6269.04 | 未披露 | 定期报告 | 2014-06-30 |
| 2014-06-17 | 6266.46 | 未披露 | 定期报告 | 2014-06-02 |
| 2014-05-09 | 6261.69 | 未披露 | 定期报告 | 2014-04-30 |
| 2014-05-08 | 6259.89 | 未披露 | 定期报告 | 2014-03-31 |
| 2014-03-17 | 6247.93 | 未披露 | 定期报告 | 2014-02-28 |
| 2014-03-17 | 6161.50 | 未披露 |
更多>>
from December 31, 2012 to December 31, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock pursuant to an at-the-market financing facility at an average per share purchase price of $8.09 net of fundraising costs of $1,570
|
2013-12-31 |
| 2013-11-07 | 6129.18 | 未披露 | 定期报告 | 2013-10-31 |
| 2013-11-07 | 6114.28 | 未披露 |
更多>>
From December 31, 2012 to September 30, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions and fundraising costs totaling $1,572
|
2013-09-30 |
| 2013-08-09 | 5965.73 | 未披露 | 定期报告 | 2013-07-31 |
| 2013-08-09 | 5831.45 | 未披露 |
更多>>
from December 31, 2012 to June 30, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions and fundraising costs totaling $894
|
2013-06-30 |
| 2013-06-07 | 5675.48 | 未披露 | 定期报告 | 2013-05-31 |
| 2013-05-08 | 5543.17 | 未披露 |
更多>>
From December 31, 2012 to March 31, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $185
|
2013-03-31 |
| 2013-03-14 | 5350.66 | 未披露 | 定期报告 | 2013-02-22 |
| 2013-03-14 | 5242.46 | 未披露 |
更多>>
From August 31, 2012 to December 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock pursuant to an at-the-market financing facility at an average per share purchase price of $5.34, net of fundraising costs totaling $185
|
2012-12-31 |
| 2013-01-09 | 5209.80 | 未披露 |
更多>>
from August 31, 2012 to November 30, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $214
|
2012-11-30 |
| 2012-11-14 | 5175.37 | 未披露 | 定期报告 | 2012-10-18 |
| 2012-11-14 | 5056.80 | 未披露 |
更多>>
from August 31, 2011 to August 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at a $4.00 per share purchase price, net of fundraising costs totaling $3,168
Issuance of common stock pursuant to an at-the-market financing facility at an average gross price of $5.10, net of fundraising costs totaling $360
|
2012-08-31 |
| 2012-07-10 | 4912.84 | 未披露 | 定期报告 | 2012-06-28 |
| 2012-07-10 | 4908.68 | 未披露 |
更多>>
from August 31, 2011 to May 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $10,564
|
2012-05-31 |
| 2012-04-09 | 4885.77 | 未披露 | 定期报告 | 2012-03-29 |
| 2012-04-09 | 4885.42 | 未披露 |
更多>>
from August 31, 2011 to February 29, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
|
2012-02-29 |
| 2012-01-06 | 4777.35 | 未披露 |
更多>>
from August 31, 2011 to November 30, 2011
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
|
2011-11-30 |
| 2011-11-14 | 4715.35 | 未披露 | 定期报告 | 2011-10-31 |
| 2011-11-14 | 3556.92 | 未披露 |
更多>>
from Aug 31,2010 to Aug 31,2011
Issuance of common stock to LPC pursuant to an equity line facility at a $3.35 average per share purchase price, net of fundraising costs and commitment shares totaling $174,202
Exercise of common stock options
Exercise of common stock warrants
|
2011-08-31 |
| 2011-06-28 | 3459.51 | 未披露 | 定期报告 | 2011-06-22 |
| 2011-07-13 | 3312.76 | 未披露 | 定期报告 | 2011-05-31 |
| 2011-04-14 | 3254.03 | 未披露 | 定期报告 | 2011-03-31 |
| 2011-04-14 | 3241.53 | 未披露 | 定期报告 | 2011-02-28 |
| 2011-01-14 | 3170.36 | 未披露 | 定期报告 | 2011-01-06 |
| 2011-01-14 | 3050.68 | 未披露 | 定期报告 | 2010-11-30 |
| 2010-11-22 | 3021.34 | 未披露 | 定期报告 | 2010-11-05 |
| 2010-11-22 | 3007.68 | 未披露 |
更多>>
from aug 31 2009 to aug 31 2010
Exercise of common stock warrants
Exercise of common stock options
Employee stock-based compensation expense
Common stock issued and warrants/options assumed with 2009 Merger
Issuance of common stock to LPC pursuant to an equity line facility at a $2.26 average per share purchase price, net of fundraising costs and commitment shares totaling $533,294
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,246,658
Issuance of common stock and warrants for the sale of units in a private placement at $3.075 per unit, including placement agent warrants, net of fundraising costs of $1,457,687
|
2010-08-31 |
| 2010-07-15 | 2494.84 | 未披露 | 定期报告 | 2010-07-14 |
| 2010-07-15 | 2408.07 | 未披露 | 定期报告 | 2010-05-31 |
| 2010-04-09 | 2258.04 | 未披露 | 定期报告 | 2010-02-28 |
| 2009-03-27 | 1597.41 | 未披露 |
更多>>
from December 31, 2007 to December 31, 2008
Issuance of common stock for exercise of options
Issuance of common stock under the Employee Stock Purchase Program
Common stock issued to Eli Lilly
|
2008-12-31 |
| 2008-03-31 | 1574.51 | 未披露 | 定期报告 | 2008-03-14 |
| 2008-03-31 | 1573.85 | 未披露 |
更多>>
from December 31, 2006 to December 31, 2007
Issuance of common stock for exercise of options
|
2007-12-31 |
| 2007-03-29 | 1570.00 | 未披露 | 定期报告 | 2007-03-15 |
| 2007-03-29 | 1567.70 | 未披露 |
更多>>
from December 31, 2005 to December 31, 2006
Issuance of common stock for exercise of options
Issuance of common stock for exercise of warrants
Redeemable convertible preferred stock converted to common stock
Effect of Merger
On October 3, 2006, we effected a reverse stock split pursuant to which each eight shares of our common stock were converted into one share of our common stock.
|
2006-12-31 |
| 2006-03-16 | 5368.07 | 未披露 |
更多>>
from December 31, 2004 to December 31, 2005
Exercise of common stock options and warrants
|
2005-12-31 |
| 2005-03-16 | 5366.55 | 未披露 | 定期报告 | 2005-02-28 |
| 2005-03-16 | 5364.55 | 未披露 |
更多>>
from December 31, 2003 to December 31, 2004
Issuance of common stock and warrants –net of expenses
Issuance of common stock for the acquisition of 52% of Oxis International Inc.
Exercise of common stock options and warrants
|
2004-12-31 |
| 2004-03-30 | 4798.40 | 未披露 | 定期报告 | 2004-03-22 |
| 2004-03-30 | 3391.99 | 未披露 |
更多>>
from December 31, 2002 to December 31, 2003
Issuance of common stock and warrants - net of expenses
Issuance of common stock for consulting services
Exercise of common stock warrants and options
|
2003-12-31 |
| 2003-03-31 | 2373.36 | 未披露 |
更多>>
from December 31, 2001 to December 31, 2002
Issuance of common stock and warrants — net of expenses
|
2002-12-31 |
| 2002-03-28 | 1724.74 | 未披露 |
更多>>
from December 31, 2000 to December 31, 2001
Issuance of common stock and warrants — net of expenses
|
2001-12-31 |
| 2001-03-22 | 1527.74 | 未披露 |
更多>>
from December 31, 1999 to December 31, 2000
Issuance of common stock and warrants — net of expenses
Shares issued to New York University and scientists
Exercise of common stock warrants and options
|
2000-12-31 |
from December 31, 2014 to December 31, 2015
Issuance of common stock:Employee stock purchase plan
Issuance of common stock:Sale of common stock
Issuance of common stock:Restricted stock units
Exercise of common stock options
Exercise of common stock warrants
Common stock issued for QUINSAIR acquisition
In April 2015, we completed a public offering of 10.925 million shares of our common stock for net proceeds of $92 million.
from December 31, 2013 to December 31, 2014
Issuance of common stock:Employee stock purchase plan
Issuance of common stock:At-the-market financing facility, net of offering costs
Exercise of common stock options
Exercise of common stock warrants
from December 31, 2012 to December 31, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock pursuant to an at-the-market financing facility at an average per share purchase price of $8.09 net of fundraising costs of $1,570
From December 31, 2012 to September 30, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions and fundraising costs totaling $1,572
from December 31, 2012 to June 30, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions and fundraising costs totaling $894
From December 31, 2012 to March 31, 2013
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $185
From August 31, 2012 to December 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock pursuant to an at-the-market financing facility at an average per share purchase price of $5.34, net of fundraising costs totaling $185
from August 31, 2012 to November 30, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $214
from August 31, 2011 to August 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at a $4.00 per share purchase price, net of fundraising costs totaling $3,168
Issuance of common stock pursuant to an at-the-market financing facility at an average gross price of $5.10, net of fundraising costs totaling $360
from August 31, 2011 to May 31, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
Issuance of common stock under an at-the-market sales agreement, net of commissions totaling $10,564
from August 31, 2011 to February 29, 2012
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
from August 31, 2011 to November 30, 2011
Exercise of common stock warrants
Exercise of common stock options
Issuance of common stock in a follow-on public offering at $4.00 per share purchase price, net of fundraising costs totaling $3,166,146
from Aug 31,2010 to Aug 31,2011
Issuance of common stock to LPC pursuant to an equity line facility at a $3.35 average per share purchase price, net of fundraising costs and commitment shares totaling $174,202
Exercise of common stock options
Exercise of common stock warrants
from aug 31 2009 to aug 31 2010
Exercise of common stock warrants
Exercise of common stock options
Employee stock-based compensation expense
Common stock issued and warrants/options assumed with 2009 Merger
Issuance of common stock to LPC pursuant to an equity line facility at a $2.26 average per share purchase price, net of fundraising costs and commitment shares totaling $533,294
Issuance of common stock and warrants in a registered direct financing at $2.00 per unit, including placement agent warrants, net of fundraising costs of $1,246,658
Issuance of common stock and warrants for the sale of units in a private placement at $3.075 per unit, including placement agent warrants, net of fundraising costs of $1,457,687
from December 31, 2007 to December 31, 2008
Issuance of common stock for exercise of options
Issuance of common stock under the Employee Stock Purchase Program
Common stock issued to Eli Lilly
from December 31, 2006 to December 31, 2007
Issuance of common stock for exercise of options
from December 31, 2005 to December 31, 2006
Issuance of common stock for exercise of options
Issuance of common stock for exercise of warrants
Redeemable convertible preferred stock converted to common stock
Effect of Merger
On October 3, 2006, we effected a reverse stock split pursuant to which each eight shares of our common stock were converted into one share of our common stock.
from December 31, 2004 to December 31, 2005
Exercise of common stock options and warrants
from December 31, 2003 to December 31, 2004
Issuance of common stock and warrants –net of expenses
Issuance of common stock for the acquisition of 52% of Oxis International Inc.
Exercise of common stock options and warrants
from December 31, 2002 to December 31, 2003
Issuance of common stock and warrants - net of expenses
Issuance of common stock for consulting services
Exercise of common stock warrants and options
from December 31, 2001 to December 31, 2002
Issuance of common stock and warrants — net of expenses
from December 31, 2000 to December 31, 2001
Issuance of common stock and warrants — net of expenses
from December 31, 1999 to December 31, 2000
Issuance of common stock and warrants — net of expenses
Shares issued to New York University and scientists
Exercise of common stock warrants and options