股本结构
单位：万股
| 公告日期 | 2025-05-28 | 2025-05-28 | 2025-05-09 | 2025-04-28 | 2025-05-09 | 2025-04-04 |
|---|---|---|---|---|---|---|
| 证券总股本 | 7534.90 | 7534.89 | 7532.27 | 7502.32 | 7498.61 | 7498.44 |
| 普通股本 | 7534.90 | 7534.89 | 7532.27 | 7502.32 | 7498.61 | 7498.44 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-05-27 | 2025-05-14 | 2025-05-02 | 2025-04-24 | 2025-03-31 | 2025-03-24 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-05-28 | 7534.90 | 未披露 | 定期报告 | 2025-05-27 |
| 2025-05-28 | 7534.89 | 未披露 | 定期报告 | 2025-05-14 |
| 2025-05-09 | 7532.27 | 未披露 | 定期报告 | 2025-05-02 |
| 2025-04-28 | 7502.32 | 未披露 | 定期报告 | 2025-04-24 |
| 2025-05-09 | 7498.61 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2025-03-31 |
| 2025-04-04 | 7498.44 | 未披露 | 定期报告 | 2025-03-24 |
| 2025-02-20 | 7493.59 | 未披露 | 定期报告 | 2025-02-14 |
| 2025-02-20 | 7440.33 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
|
2024-12-31 |
| 2024-11-12 | 7438.64 | 未披露 | 定期报告 | 2024-11-05 |
| 2024-11-12 | 7433.53 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2024-09-30 |
| 2024-08-07 | 7427.30 | 未披露 | 定期报告 | 2024-08-01 |
| 2024-08-07 | 7425.64 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Restricted stock units vested
Forfeitures of restricted stock awards
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2024-06-30 |
| 2024-05-02 | 7408.64 | 未披露 | 定期报告 | 2024-04-26 |
| 2024-05-02 | 7406.12 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2024-03-31 |
| 2024-04-05 | 7405.99 | 未披露 | 定期报告 | 2024-03-25 |
| 2024-02-27 | 7378.68 | 未披露 | 定期报告 | 2024-02-21 |
| 2024-02-27 | 7348.67 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock in underwritten public offering, net of issuance cost
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
|
2023-12-31 |
| 2023-12-06 | 7206.16 | 未披露 |
更多>>
Common stock offered 9,482,758 shares by the company
|
2023-12-07 |
| 2023-11-02 | 6257.89 | 未披露 | 定期报告 | 2023-11-01 |
| 2023-11-02 | 6257.51 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
Restricted stock units vested
Exercise of stock options
|
2023-09-30 |
| 2023-08-02 | 6256.98 | 未披露 | 定期报告 | 2023-07-28 |
| 2023-08-02 | 6256.44 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Exercise of stock options
Restricted stock units vested
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
|
2023-06-30 |
| 2023-05-03 | 6252.31 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-05-03 | 6252.34 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2023-03-31 |
| 2023-04-07 | 6252.34 | 未披露 | 定期报告 | 2023-03-30 |
| 2023-02-28 | 6249.88 | 未披露 | 定期报告 | 2023-02-22 |
| 2023-02-28 | 6242.31 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock to GSK
Issuance of common stock in private placement, net of issuance costs
Issuance of common stock under at-the-market offering, net of issuance costs
Issuance of restricted stock awards
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
|
2022-12-31 |
| 2022-11-03 | 6238.23 | 未披露 | 定期报告 | 2022-10-31 |
| 2022-11-03 | 6238.26 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock in private placement, net of issuance costs
Issuance of common stock under at-the-market offering, net of issuance costs
Exercise of stock options
Issuance of common stock to GSK
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
|
2022-09-30 |
| 2022-09-26 | 6240.11 | 未披露 | 定期报告 | 2022-09-15 |
| 2022-08-04 | 4944.27 | 未披露 | 定期报告 | 2022-07-29 |
| 2022-08-04 | 4943.62 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
Restricted stock units vested
Exercise of stock options
|
2022-06-30 |
| 2022-05-05 | 4941.38 | 未披露 | 定期报告 | 2022-04-29 |
| 2022-05-05 | 4940.76 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of restricted stock awards
Exercise of stock options
Forfeitures of restricted stock awards
|
2022-03-31 |
| 2022-04-08 | 4942.48 | 未披露 | 定期报告 | 2022-03-24 |
| 2022-02-24 | 4934.38 | 未披露 | 定期报告 | 2022-02-18 |
| 2022-02-24 | 4924.80 | 未披露 |
更多>>
From December 31,2020 to December 31,2021
Exercise of stock options
Issuance of restricted stock awards
Forfeitures of restricted stock awards
|
2021-12-31 |
| 2021-11-04 | 4924.92 | 未披露 | 定期报告 | 2021-10-29 |
| 2021-11-04 | 4920.84 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Forfeitures of restricted stock awards
Issuance of restricted stock awards
Exercise of stock options
|
2021-09-30 |
| 2021-08-04 | 4912.79 | 未披露 | 定期报告 | 2021-07-29 |
| 2021-08-04 | 4910.31 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Forfeitures of restricted stock awards
Issuance of restricted stock awards
Exercise of stock options
|
2021-06-30 |
| 2021-05-05 | 4906.11 | 未披露 | 定期报告 | 2021-04-30 |
| 2021-05-05 | 4902.42 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Issuance of restricted stock awards
Exercise of stock options
|
2021-03-31 |
| 2021-02-25 | 4897.61 | 未披露 | 定期报告 | 2021-02-19 |
| 2021-02-25 | 4881.96 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Exercise of stock options
Issuance of common stock upon closing of follow-on offering, net of $17,908,000 in issuance cost
Forfeitures of restricted stock awards
|
2020-12-31 |
| 2020-11-12 | 4876.72 | 未披露 | 定期报告 | 2020-11-06 |
| 2020-10-13 | 4791.85 | 未披露 |
更多>>
1.Common stock offered by the company 4,901,960 shares of common stock.
2.The number of shares of common stock to be outstanding after this offering is based on 43,016,501 shares of common stock (which includes 989,303 issued but unvested shares of restricted common stock subject to repurchase) outstanding as of June 30, 2020.
|
2020-10-13 |
| 2020-11-12 | 4312.88 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Exercise of stock options
Forfeitures of restricted stock awards
|
2020-09-30 |
| 2020-08-12 | 4301.84 | 未披露 | 定期报告 | 2020-08-10 |
| 2020-10-08 | 4301.65 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Exercise of stock options
|
2020-06-30 |
| 2020-05-12 | 4301.05 | 未披露 | 定期报告 | 2020-05-06 |
| 2020-05-12 | 4300.37 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Exercise of stock options
Forfeitures of restricted stock awards
|
2020-03-31 |
| 2020-04-02 | 4300.14 | 未披露 | 定期报告 | 2020-03-24 |
| 2020-03-12 | 4300.12 | 未披露 | 定期报告 | 2020-03-09 |
| 2020-03-12 | 4300.61 | 未披露 |
更多>>
From December 31, 2018 to December 31, 2019
Issuance of Series A convertible preferred shares, net
Issuance of Series B convertible preferred shares, net of $413,063 in legal costs
Conversion of convertible preferred stock into common stock
Stock-based compensation, net of forfeitures
Issuance of common stock upon closing of initial public offering, net of $16,570 in issuance cost
Exercise of stock options
|
2019-12-31 |
| 2019-11-12 | 4300.61 | 未披露 | 定期报告 | 2019-11-12 |
| 2019-11-12 | 4323.34 | 未披露 |
更多>>
from June 30, 2019 to September 30, 2019
Conversion of convertible preferred stock into common stock
Issuance of common stock upon closing of initial public offering, net of $16,570 in issuance cost
Exercise of stock options
|
2019-09-30 |
| 2019-09-13 | 4188.30 | 未披露 |
更多>>
1.Common stock offered by us 9,000,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 32,882,995 shares of our common stock (which includes 2,118,689 issued but unvested shares of restricted common stock subject to repurchase) outstanding as of June 30, 2019
|
2019-09-13 |
| 2019-08-16 | 2032.64 | 19607.68 | 定期报告 | 2019-06-30 |
From December 31, 2024 to March 31, 2025
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From December 31, 2023 to December 31, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
From June 30, 2024 to September 30, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From March 31, 2024 to June 30, 2024
Restricted stock units vested
Forfeitures of restricted stock awards
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From December 31, 2023 to March 31, 2024
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From December 31, 2022 to December 31, 2023
Issuance of common stock in underwritten public offering, net of issuance cost
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Common stock offered 9,482,758 shares by the company
From June 30, 2023 to September 30, 2023
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
Restricted stock units vested
Exercise of stock options
From March 31, 2023 to June 30, 2023
Exercise of stock options
Restricted stock units vested
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
From December 31, 2022 to March 31, 2023
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From December 31, 2021 to December 31, 2022
Issuance of common stock to GSK
Issuance of common stock in private placement, net of issuance costs
Issuance of common stock under at-the-market offering, net of issuance costs
Issuance of restricted stock awards
Forfeitures of restricted stock awards
Restricted stock units vested
Exercise of stock options
Shares of common stock used to satisfy tax withholding obligations
From June 30, 2022 to September 30, 2022
Issuance of common stock in private placement, net of issuance costs
Issuance of common stock under at-the-market offering, net of issuance costs
Exercise of stock options
Issuance of common stock to GSK
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
From March 31, 2022 to June 30, 2022
Forfeitures of restricted stock awards
Shares of common stock used to satisfy tax withholding obligations
Restricted stock units vested
Exercise of stock options
From December 31, 2021 to March 31, 2022
Issuance of restricted stock awards
Exercise of stock options
Forfeitures of restricted stock awards
From December 31,2020 to December 31,2021
Exercise of stock options
Issuance of restricted stock awards
Forfeitures of restricted stock awards
From June 30, 2021 to September 30, 2021
Forfeitures of restricted stock awards
Issuance of restricted stock awards
Exercise of stock options
From March 31, 2021 to June 30, 2021
Forfeitures of restricted stock awards
Issuance of restricted stock awards
Exercise of stock options
From December 31, 2020 to March 31, 2021
Issuance of restricted stock awards
Exercise of stock options
From December 31,2019 to December 31,2020
Exercise of stock options
Issuance of common stock upon closing of follow-on offering, net of $17,908,000 in issuance cost
Forfeitures of restricted stock awards
1.Common stock offered by the company 4,901,960 shares of common stock.
2.The number of shares of common stock to be outstanding after this offering is based on 43,016,501 shares of common stock (which includes 989,303 issued but unvested shares of restricted common stock subject to repurchase) outstanding as of June 30, 2020.
From June 30, 2020 to September 30, 2020
Exercise of stock options
Forfeitures of restricted stock awards
From March 31, 2020 to June 30, 2020
Exercise of stock options
From December 31, 2019 to March 31, 2020
Exercise of stock options
Forfeitures of restricted stock awards
From December 31, 2018 to December 31, 2019
Issuance of Series A convertible preferred shares, net
Issuance of Series B convertible preferred shares, net of $413,063 in legal costs
Conversion of convertible preferred stock into common stock
Stock-based compensation, net of forfeitures
Issuance of common stock upon closing of initial public offering, net of $16,570 in issuance cost
Exercise of stock options
from June 30, 2019 to September 30, 2019
Conversion of convertible preferred stock into common stock
Issuance of common stock upon closing of initial public offering, net of $16,570 in issuance cost
Exercise of stock options
1.Common stock offered by us 9,000,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 32,882,995 shares of our common stock (which includes 2,118,689 issued but unvested shares of restricted common stock subject to repurchase) outstanding as of June 30, 2019