股本结构
单位：万股
| 公告日期 | 2025-11-13 | 2025-11-13 | 2025-08-07 | 2025-08-07 | 2025-06-04 | 2025-05-08 |
|---|---|---|---|---|---|---|
| 证券总股本 | 12823.01 | 12821.51 | 12177.69 | 12177.58 | 11914.48 | 9989.29 |
| 普通股本 | 12823.01 | 12821.51 | 12177.69 | 12177.58 | 11914.48 | 9989.29 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-10-31 | 2025-09-30 | 2025-07-31 | 2025-06-30 | 2025-06-05 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-11-13 | 12823.01 | 未披露 | 定期报告 | 2025-10-31 |
| 2025-11-13 | 12821.51 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
|
2025-09-30 |
| 2025-08-07 | 12177.69 | 未披露 | 定期报告 | 2025-07-31 |
| 2025-08-07 | 12177.58 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from warrant exercise
Issuance of common stock under offering, less issuance costs
|
2025-06-30 |
| 2025-06-04 | 11914.48 | 未披露 |
更多>>
Common stock offered 17,400,000 shares by the company
|
2025-06-05 |
| 2025-04-29 | 10174.48 | 未披露 | 定期报告 | 2025-04-23 |
| 2025-05-08 | 9989.29 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from warrant exercise
|
2025-03-31 |
| 2025-03-18 | 9668.22 | 未披露 | 定期报告 | 2025-03-14 |
| 2025-03-18 | 9360.26 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock under offering, less issuance costs
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
|
2024-12-31 |
| 2024-12-16 | 8936.57 | 未披露 |
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Common stock offered 12,500,000 shares by the company
|
2024-12-17 |
| 2024-11-06 | 7686.57 | 未披露 | 定期报告 | 2024-10-31 |
| 2024-11-06 | 7545.44 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
|
2024-09-30 |
| 2024-08-08 | 7259.19 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
|
2024-06-30 |
| 2024-03-20 | 7043.51 | 未披露 | 定期报告 | 2024-04-15 |
| 2024-05-07 | 6896.02 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
|
2024-03-31 |
| 2024-03-20 | 6896.02 | 未披露 | 定期报告 | 2024-03-20 |
| 2024-03-20 | 6828.37 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
|
2023-12-31 |
| 2023-11-09 | 6385.76 | 未披露 | 定期报告 | 2023-11-09 |
| 2023-11-09 | 6385.53 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
|
2023-09-30 |
| 2023-08-10 | 6385.07 | 未披露 | 定期报告 | 2023-08-10 |
| 2023-08-10 | 6309.85 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
|
2023-06-30 |
| 2023-05-11 | 6006.95 | 未披露 | 定期报告 | 2023-05-11 |
| 2023-05-01 | 6006.93 | 未披露 | 定期报告 | 2023-04-28 |
| 2023-05-11 | 6006.54 | 未披露 |
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From December 31, 2022 to March 31, 2023
Issuance of common stock from exercise of stock options
|
2023-03-31 |
| 2023-03-16 | 6004.51 | 未披露 | 定期报告 | 2023-03-16 |
| 2023-03-16 | 5994.34 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock and warrants under public offering and private placement, less issuance costs
Issuance of common stock from warrant exercise
|
2022-12-31 |
| 2022-11-10 | 5992.29 | 未披露 | 定期报告 | 2022-11-10 |
| 2022-11-10 | 5832.25 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of common stock from exercise of stock options
Issuance of common stock and warrants under public offering, less issuance costs
Issuance of common stock from warrant exercise
|
2022-09-30 |
| 2022-09-23 | 5832.25 | 未披露 |
更多>>
The company is offering 14,252,670 shares common stock
|
2022-09-27 |
| 2022-09-22 | 4406.98 | 未披露 | 定期报告 | 2022-08-31 |
| 2022-08-11 | 4277.06 | 未披露 | 定期报告 | 2022-08-11 |
| 2022-08-11 | 3971.96 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock and warrants under private placements, less issuance costs
Issuance of common stock from warrant exercise
|
2022-06-30 |
| 2022-05-02 | 3868.56 | 未披露 | 定期报告 | 2022-04-25 |
| 2022-05-12 | 3080.58 | 未披露 |
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From December 31, 2021 to March 31, 2022
Issuance of common stock from warrant exercise
|
2022-03-31 |
| 2022-03-17 | 3080.58 | 未披露 | 定期报告 | 2022-03-17 |
| 2022-03-17 | 2850.58 | 未披露 |
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From December 31, 2020 to December 31, 2021
Issuance of common stock from employee stock purchase plan
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock to Lincoln Park Capital Fund
Issuance of common stock and warrants under private placements, less issuance costs
Issuance of common stock from warrant exercise
|
2021-12-31 |
| 2021-11-05 | 2584.66 | 未披露 | 定期报告 | 2021-11-03 |
| 2021-10-15 | 2399.47 | 未披露 | 定期报告 | 2021-10-05 |
| 2021-11-10 | 2162.15 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
|
2021-09-30 |
| 2021-08-27 | 2159.85 | 未披露 | 定期报告 | 2021-07-31 |
| 2021-07-07 | 2156.77 | 未披露 | 定期报告 | 2021-07-02 |
| 2021-08-12 | 2145.95 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock to Lincoln Park Capital Fund
|
2021-06-30 |
| 2021-07-07 | 2088.63 | 未披露 | 定期报告 | 2021-06-17 |
| 2021-04-27 | 1992.73 | 未披露 | 定期报告 | 2021-04-19 |
| 2021-05-13 | 1991.44 | 未披露 |
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From December 31, 2020 to March 31, 2021
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
|
2021-03-31 |
| 2021-03-25 | 1991.44 | 未披露 | 定期报告 | 2021-03-24 |
| 2021-03-25 | 1854.68 | 未披露 |
更多>>
from December 31, 2019 to December 31, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock from employee stock purchase plan
Issuance of common stock under at-the-market sales agreement, net of commissions and allocated fees
|
2020-12-31 |
| 2020-11-12 | 1838.08 | 未披露 | 定期报告 | 2020-11-11 |
| 2020-11-12 | 1832.11 | 未披露 |
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from June 30, 2020 to September 30, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and fees
|
2020-09-30 |
| 2020-08-13 | 1824.01 | 未披露 | 定期报告 | 2020-08-13 |
| 2020-08-13 | 1785.12 | 未披露 |
更多>>
from March 31, 2020 to June 30, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
|
2020-06-30 |
| 2020-06-26 | 1784.36 | 未披露 | 定期报告 | 2020-06-25 |
| 2019-08-12 | 1783.46 | 未披露 |
更多>>
from March 31, 2019 to June 30,2019
Dividends accrued on redeemable convertible preferred stock
Conversion of redeemable convertible preferred stock to common stock in connection with initial public offering
Issuance of common stock from exercise of stock options
|
2019-06-30 |
| 2019-05-08 | 1777.18 | 未披露 |
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1.Common stock offered 5,500,000 shares
2.The number of shares of our common stock to be outstanding after this offering and the concurrent private placement is based on 446,494 shares of our common stock outstanding as of March 31, 2019 and an additional 10,325,257 shares of our common stock issuable upon the automatic conversion of all outstanding shares of our convertible preferred stock and the accrued dividends on our convertible preferred stock upon the closing of this offering (based on an assumed closing date of March 31, 2019)
3.gives effect to a one-for-9.5 reverse stock split of our common stock that was effected on April 22, 2019
|
2019-05-07 |
| 2019-06-14 | 44.65 | 8294.36 |
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From December 31, 2018 To March 31, 2019
Issuance of Series C redeemable convertible preferred stock, net of issuance costs
Issuance of common stock from exercise of stock options
|
2019-03-31 |
| 2019-04-05 | 424.18 | 未披露 | 定期报告 | 2019-01-31 |
From June 30, 2025 to September 30, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
From March 31, 2025 to June 30, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from warrant exercise
Issuance of common stock under offering, less issuance costs
Common stock offered 17,400,000 shares by the company
From December 31, 2024 to March 31, 2025
Issuance of common stock from exercise of stock options
Issuance of common stock from warrant exercise
From December 31, 2023 to December 31, 2024
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock under offering, less issuance costs
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
Common stock offered 12,500,000 shares by the company
From June 30, 2024 to September 30, 2024
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
From March 31, 2024 to June 30, 2024
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
From December 31, 2023 to March 31, 2024
Issuance of common stock from exercise of stock options
Issuance of common stock from pre-funded warrant exercise
From December 31, 2022 to December 31, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
From June 30, 2023 to September 30, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
From March 31, 2023 to June 30, 2023
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock from pre-funded warrant exercise
From December 31, 2022 to March 31, 2023
Issuance of common stock from exercise of stock options
From December 31, 2021 to December 31, 2022
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock and warrants under public offering and private placement, less issuance costs
Issuance of common stock from warrant exercise
From June 30, 2022 to September 30, 2022
Issuance of common stock from exercise of stock options
Issuance of common stock and warrants under public offering, less issuance costs
Issuance of common stock from warrant exercise
The company is offering 14,252,670 shares common stock
From March 31, 2022 to June 30, 2022
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock and warrants under private placements, less issuance costs
Issuance of common stock from warrant exercise
From December 31, 2021 to March 31, 2022
Issuance of common stock from warrant exercise
From December 31, 2020 to December 31, 2021
Issuance of common stock from employee stock purchase plan
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock to Lincoln Park Capital Fund
Issuance of common stock and warrants under private placements, less issuance costs
Issuance of common stock from warrant exercise
From June 30, 2021 to September 30, 2021
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
From March 31, 2021 to June 30, 2021
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
Issuance of common stock from Employee Stock Purchase Plan
Issuance of common stock to Lincoln Park Capital Fund
From December 31, 2020 to March 31, 2021
Issuance of common stock under the at-the-market sales agreement, net of commissions and allocated fees
from December 31, 2019 to December 31, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock from employee stock purchase plan
Issuance of common stock under at-the-market sales agreement, net of commissions and allocated fees
from June 30, 2020 to September 30, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock under the at-the-market sales agreement, net of commissions and fees
from March 31, 2020 to June 30, 2020
Issuance of common stock from exercise of stock options
Issuance of common stock from Employee Stock Purchase Plan
from March 31, 2019 to June 30,2019
Dividends accrued on redeemable convertible preferred stock
Conversion of redeemable convertible preferred stock to common stock in connection with initial public offering
Issuance of common stock from exercise of stock options
1.Common stock offered 5,500,000 shares
2.The number of shares of our common stock to be outstanding after this offering and the concurrent private placement is based on 446,494 shares of our common stock outstanding as of March 31, 2019 and an additional 10,325,257 shares of our common stock issuable upon the automatic conversion of all outstanding shares of our convertible preferred stock and the accrued dividends on our convertible preferred stock upon the closing of this offering (based on an assumed closing date of March 31, 2019)
3.gives effect to a one-for-9.5 reverse stock split of our common stock that was effected on April 22, 2019
From December 31, 2018 To March 31, 2019
Issuance of Series C redeemable convertible preferred stock, net of issuance costs
Issuance of common stock from exercise of stock options