股本结构

单位:万股
公告日期 2026-02-25 2026-02-25 2025-10-29 2025-10-29 2025-08-01 2025-07-30
证券总股本 4382.77 4364.32 4305.66 4290.28 4520.00 4522.63
普通股本 4382.77 4364.32 4305.66 4290.28 4520.00 4522.63
优先股 未披露 未披露 未披露 未披露 未披露 未披露
其他 未披露 未披露 未披露 未披露 未披露 未披露
变动日期 2026-02-18 2025-12-31 2025-10-22 2025-09-30 2025-07-30 2025-07-23
注释:中概股证券总股本=普通股股本/ 存托凭证比例

历史变动

公告日期 变动后普通股本(万股) 变动后优先股(万股) 变动原因 变动日期
2026-02-25 4382.77 未披露 定期报告 2026-02-18
2026-02-25 4364.32 未披露
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From December 31, 2024 to December 31, 2025 Common stock issued for RSUs vested Exercise of stock options Share repurchase Excise tax on net share repurchase
2025-12-31
2025-10-29 4305.66 未披露 定期报告 2025-10-22
2025-10-29 4290.28 未披露
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From July 1, 2025 to September 30, 2025 Exercise of stock options Share repurchase Excise tax on net share repurchase
2025-09-30
2025-08-01 4520.00 未披露 定期报告 2025-07-30
2025-07-30 4522.63 未披露 定期报告 2025-07-23
2025-07-30 4521.53 未披露
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From April 1, 2025 to June 30, 2025 Exercise of stock options
2025-06-30
2025-04-30 4510.66 未披露 定期报告 2025-04-23
2025-04-29 4509.26 未披露 定期报告 2025-04-14
2025-04-30 4507.46 未披露
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From January 1, 2025 to March 31, 2025 Common stock issued for RSUs vested Exercise of stock options
2025-03-31
2025-04-29 4507.16 未披露 定期报告 2025-03-19
2025-02-26 4491.22 未披露 定期报告 2025-02-19
2025-02-26 4483.13 未披露
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From December 31, 2023 to December 31, 2024 Common stock issued for RSUs vested Exercise of stock options Share repurchase Excise tax on net share repurchase
2024-12-31
2024-10-30 4464.45 未披露 定期报告 2024-10-23
2024-10-30 4461.57 未披露
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From July 1, 2024 to September 30, 2024 Exercise of stock options Share repurchase Excise tax on net share repurchase
2024-09-30
2024-07-31 4449.12 未披露 定期报告 2024-07-24
2024-07-31 4442.17 未披露
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From April 1, 2024 to June 30, 2024 Exercise of stock options
2024-06-30
2024-04-29 4436.65 未披露 定期报告 2024-04-29
2024-05-01 4435.57 未披露 定期报告 2024-04-24
2024-04-29 4433.05 未披露 定期报告 2024-04-15
2024-05-01 4420.45 未披露
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From January 1, 2024 to March 31, 2024 Common stock issued for RSUs vested Exercise of stock options
2024-03-31
2024-04-29 4415.91 未披露 定期报告 2024-03-25
2024-02-21 4705.85 未披露 定期报告 2024-02-14
2024-02-21 4704.05 未披露
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From December 31, 2022 to December 31, 2023 Common stock issued for RSUs vested Exercise of stock options
2023-12-31
2023-11-01 4699.36 未披露 定期报告 2023-10-25
2023-11-01 4698.12 未披露
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From July 1, 2023 to September 30, 2023 Exercise of stock options
2023-09-30
2023-08-02 4693.26 未披露 定期报告 2023-07-26
2023-08-02 4691.33 未披露
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from April 1, 2023 to June 30, 2023 Exercise of stock options
2023-06-30
2023-05-03 4684.65 未披露 定期报告 2023-04-26
2023-04-28 4674.45 未披露 定期报告 2023-04-10
2023-05-03 4669.85 未披露
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From January 1, 2023 to March 31, 2023 Common stock issued for RSUs vested Exercise of stock options
2023-03-31
2023-04-28 4661.85 未披露 定期报告 2023-03-17
2023-02-22 4630.17 未披露 定期报告 2023-02-15
2023-02-22 4603.21 未披露
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From December 31, 2021 to December 31, 2022 Shares issued under ESPP Common stock issued for RSUs vested Exercise of stock options
2022-12-31
2022-11-02 4557.70 未披露 定期报告 2022-10-26
2022-11-02 4556.31 未披露
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From July 1, 2022 to September 30, 2022 Shares issued under employee stock purchase plan (ESPP)
2022-09-30
2022-08-03 4551.63 未披露 定期报告 2022-07-27
2022-08-03 4549.00 未披露
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From April 1, 2022 to June 30, 2022 Exercise of stock options
2022-06-30
2022-05-04 4529.95 未披露 定期报告 2022-04-27
2022-04-29 4529.35 未披露 定期报告 2022-04-11
2022-05-04 4528.75 未披露
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From January 1, 2022 to March 31, 2022 Common stock issued for RSUs vested Exercise of stock options
2022-03-31
2022-02-24 4513.21 未披露 定期报告 2022-02-17
2022-02-24 4510.78 未披露
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From December 31, 2020 to December 31, 2021 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
2021-12-31
2021-11-03 4503.65 未披露 定期报告 2021-10-27
2021-11-03 4502.15 未披露
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From July 1, 2021 to September 30, 2021 Exercise of stock options
2021-09-30
2021-08-19 4492.35 未披露 定期报告 2021-08-10
2021-08-19 4489.19 未披露 定期报告 2021-08-02
2021-08-04 4489.15 未披露 定期报告 2021-07-28
2021-08-04 4489.07 未披露
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From April 1, 2021 to June 30, 2021 Exercise of stock options
2021-06-30
2021-04-29 4479.57 未披露 定期报告 2021-04-30
2021-05-05 4479.64 未披露 定期报告 2021-04-28
2021-04-29 4479.49 未披露 定期报告 2021-04-10
2021-05-05 4478.86 未披露
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from January 1, 2021 to March 31, 2021 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
2021-03-31
2021-02-24 4454.43 未披露 定期报告 2021-02-17
2021-02-24 4450.71 未披露
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From December 31,2019 to December 31,2020 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
2020-12-31
2020-10-28 4444.05 未披露 定期报告 2020-10-21
2020-10-28 4443.99 未披露
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From July 1, 2020 to September 30, 2020 Shares issued under employee stock purchase plan
2020-09-30
2020-07-29 4441.18 未披露 定期报告 2020-07-22
2020-07-29 4435.68 未披露
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From April 1, 2020 to June 30, 2020 Exercise of stock options
2020-06-30
2020-04-29 4401.23 未披露 定期报告 2020-04-22
2020-04-29 4400.21 未披露
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From January 1, 2020 to March 31, 2020 Common stock issued for RSUs vested
2020-03-31
2020-02-26 4388.50 未披露 定期报告 2020-02-19
2020-02-26 4388.46 未披露
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From December 31, 2018 to December 31, 2019 Common stock issued upon RSU vesting Exercise of stock options
2019-12-31
2019-10-30 4388.14 未披露 定期报告 2019-10-23
2019-10-30 4388.06 未披露
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from January 1, 2019 to September 30, 2019 Common stock issued upon RSU vesting Exercise of stock options
2019-09-30
2019-07-31 4385.03 未披露 定期报告 2019-07-24
2019-07-31 4384.85 未披露
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from April 1, 2019 to June 30, 2019 Common stock issued upon RSU vesting
2019-06-30
2019-05-01 4381.09 未披露 定期报告 2019-04-24
2019-04-29 4381.07 未披露 定期报告 2019-04-10
2019-05-01 4380.57 未披露
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from January 1, 2019 to March 31, 2019 Exercise of stock options
2019-03-31
2019-02-27 4372.24 未披露 定期报告 2019-02-20
2019-02-27 4358.84 未披露
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from December 31, 2017 to December 31, 2018 Exercise of stock options
2018-12-31
2018-10-31 4358.72 未披露 定期报告 2018-10-24
2018-10-31 4358.60 未披露 定期报告 2018-09-30
2018-08-01 4356.30 未披露 定期报告 2018-07-25
2018-08-01 4356.23 未披露 定期报告 2018-06-30
2018-05-02 4354.40 未披露 定期报告 2018-04-25
2018-05-02 4343.59 未披露 定期报告 2018-03-31
2018-02-21 4323.97 未披露 定期报告 2018-02-14
2018-02-21 4323.96 未披露
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from December 31, 2016 to December 31, 2017 Shares issued under employee stock purchase plan Exercise of stock options Shares issued upon expiration of warrants Repurchase of shares
2017-12-31
2017-10-25 4321.11 未披露 定期报告 2017-10-18
2017-10-25 4320.67 未披露 定期报告 2017-09-30
2017-07-27 4344.29 未披露 定期报告 2017-07-20
2017-07-27 4343.61 未披露 定期报告 2017-06-30
2017-04-26 4505.69 未披露 定期报告 2017-04-19
2017-04-28 4505.48 未披露 定期报告 2017-04-10
2017-04-26 4505.26 未披露 定期报告 2017-03-31
2017-02-22 4496.16 未披露 定期报告 2017-02-10
2017-02-22 4296.59 未披露
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from December 31, 2015 to December 31, 2016 Conversion of 2016 convertible notes Exercise of stock options Shares issued upon expiration of warrants Repurchase of shares
2016-12-31
2016-10-27 4241.55 未披露 定期报告 2016-10-20
2016-10-27 4266.20 未披露 定期报告 2016-09-30
2016-07-28 4346.78 未披露 定期报告 2016-07-21
2016-07-28 4373.26 未披露 定期报告 2016-06-30
2016-04-28 4454.91 未披露 定期报告 2016-04-27
2016-04-28 4462.20 未披露 定期报告 2016-04-21
2016-04-28 4488.43 未披露 定期报告 2016-03-31
2016-02-25 4535.27 未披露 定期报告 2016-02-12
2016-02-25 4576.08 未披露
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from December 31, 2014 to December 31, 2015 Shares issued under employee stock purchase plan Conversion of 2016 convertible notes Exercise of stock options Repurchase of shares
2015-12-31
2015-10-27 4562.94 未披露 定期报告 2015-10-21
2015-10-27 4558.30 未披露 定期报告 2015-09-30
2015-07-28 4554.05 未披露 定期报告 2015-07-21
2015-07-28 4569.34 未披露 定期报告 2015-06-30
2015-04-28 4626.09 未披露 定期报告 2015-04-21
2015-04-28 4637.01 未披露 定期报告 2015-03-31
2015-02-24 4666.55 未披露 定期报告 2015-02-17
2015-02-24 4710.77 未披露
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from December 31, 2013 to December 31, 2014 Shares issued under employee stock purchase plan Conversion of 2016 convertible notes Exercise of stock options Repurchase of shares
2014-12-31
2014-10-28 4750.89 未披露 定期报告 2014-10-21
2014-10-28 4743.60 未披露 定期报告 2014-09-30
2014-07-29 4726.94 未披露 定期报告 2014-07-21
2014-07-29 4723.05 未披露 定期报告 2014-06-30
2014-04-30 4796.93 未披露 定期报告 2014-04-30
2014-04-29 4817.62 未披露 定期报告 2014-04-22
2014-04-29 4965.85 未披露 定期报告 2014-03-31
2014-02-25 5047.71 未披露 定期报告 2014-02-18
2014-02-25 5038.81 未披露
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from December 31, 2012 to December 31, 2013 Shares issued under employee stock purchase plan Exercise of stock options Repurchase of shares
2013-12-31
2013-10-29 5022.66 未披露 定期报告 2013-10-22
2013-10-29 5017.74 未披露 定期报告 2013-09-30
2013-07-25 4992.35 未披露 定期报告 2013-07-19
2013-07-25 4984.08 未披露 定期报告 2013-06-30
2013-04-30 4967.01 未披露 定期报告 2013-04-29
2013-04-25 4970.76 未披露 定期报告 2013-04-18
2013-04-25 5024.53 未披露 定期报告 2013-03-31
2013-02-26 5018.34 未披露 定期报告 2013-02-18
2013-02-26 5016.60 未披露
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from December 31, 2011 to December 31, 2012 Exercise of stock options Repurchase of shares
2012-12-31
2012-11-01 5080.07 未披露 定期报告 2012-10-25
2012-11-01 5116.27 未披露 定期报告 2012-09-30
2012-07-26 5171.88 未披露 定期报告 2012-07-20
2012-07-26 5170.46 未披露 定期报告 2012-06-30
2012-04-26 5368.54 未披露 定期报告 2012-04-20
2012-04-26 5368.26 未披露 定期报告 2012-03-31
2012-02-28 5362.67 未披露 定期报告 2012-02-23
2012-02-28 5360.96 未披露
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from Dec 31,2010 to Dec 31,2011 Conversion of 2011 convertible notes and exercise of convertible note hedge Exercise of stock options Shares received as part of Medicomp sale Share repurchase
2011-12-31
2011-10-27 5833.46 未披露 定期报告 2011-10-21
2011-10-27 5833.45 未披露 定期报告 2011-09-30
2011-07-28 5831.66 未披露 定期报告 2011-07-22
2011-07-28 5831.43 未披露 定期报告 2011-06-30
2011-04-28 5807.00 未披露 定期报告 2011-04-25
2011-04-28 5799.06 未披露 定期报告 2011-03-31
2011-02-24 5775.39 未披露 定期报告 2011-02-18
2011-02-24 5755.59 未披露
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from dec 31 2009 to dec 31 2010 Exercise of stock options Stock issued in connection with conversion of Convertible Senior Notes
2010-12-31
2010-10-28 5691.71 未披露 定期报告 2010-10-22
2010-10-28 5677.81 未披露 定期报告 2010-09-30
2010-07-28 5645.03 未披露 定期报告 2010-07-23
2010-07-28 5639.38 未披露 定期报告 2010-06-30
2010-04-29 5585.22 未披露 定期报告 2010-04-26
2010-04-29 5564.71 未披露 定期报告 2010-03-31
2010-02-26 5660.83 未披露 定期报告 2010-02-19
2010-02-26 5422.08 未披露
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from December 31,2008 to December 31,2009 Issuance of stock dividend Exercise of stock options the two-for-one split of our common stock on September 22, 2009.
2009-12-31
2009-02-26 2643.59 未披露 定期报告 2009-02-20
2009-02-26 2643.14 未披露
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from December 31,2007 to December 31,2008 Exercise of stock options Issuance of treasury stock
2008-12-31
2008-02-29 2234.40 未披露 定期报告 2008-02-22
2008-02-29 2224.76 未披露
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from December 31,2006 to December 31,2007 Exercise of stock options Treasury stock repurchases
2007-12-31
2007-02-28 2131.47 未披露 定期报告 2007-02-20
2007-02-28 2147.51 未披露
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from December 31,2005 to December 31,2006 Exercise of stock options Treasury stock repurchases
2006-12-31
2006-02-27 2337.09 未披露 定期报告 2006-02-21
2006-02-27 2331.84 未披露
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from December 31,2004 to December 31,2005 Exercise of stock options
2005-12-31
2005-02-25 2249.30 未披露 定期报告 2005-02-09
2005-02-25 2242.85 未披露
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from December 31,2003 to December 31,2004 Exercise of stock options Settlement of shares due to sellers of Medicomp
2004-12-31
2004-03-12 2133.24 未披露 定期报告 2004-03-01
2004-03-12 2130.97 未披露
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from December 31,2002 to December 31,2003 Exercise of stock options
2003-12-31
2003-03-19 2092.41 未披露 定期报告 2003-03-12
2003-03-19 2092.29 未披露
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from December 31,2001 to December 31,2002 Settlement of escrow items with sellers of Cooke Pharma Exercise of stock options
2002-12-31
2002-10-17 2091.87 未披露 定期报告 2002-10-10
2002-03-20 2022.52 未披露 定期报告 2002-03-13
2002-03-20 2022.52 未披露
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from December 31,2000 to December 31,2001 Stock issued in exchange for services Exercise of stock options Purchases of treasury stock
2001-12-31
2001-03-30 2074.14 未披露 定期报告 2001-03-15
2001-03-30 2043.41 未披露
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from December 31, 1999 to December 31,2000 Issuance of common stock through private sales Stock issued for acquisition of Cooke Pharma, Inc. Stock issued for acquisition of Medicomp, Inc. and Telemedical Procedures, LLC Stock issued for investment in Synergy Pharmaceuticals, Inc. Adjustment to SynQuest, Inc. escrow Stock issued for exclusive license agreement Stock issued in exchange for services Exercise of stock options Purchases of treasury stock
2000-12-31
2000-03-22 1850.32 未披露 定期报告 2000-03-17
2000-03-22 1600.32 未披露
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from December 31, 1998 to December 31, 1999 Issuance of common stock through private sales Issuance of common stock through initial public offering Issuance of common stock to underwriters for over-allotment shares Stock issued for exclusive license agreement Stock issued for acquisition of SynQuest, Inc.
1999-12-31
2000-03-22 1011.56 未披露
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from December 31, 1997 to December 31, 1998 Issuance of common stock Stock issued in exchange for services Stock issued for exclusive license agreement
1998-12-31
From December 31, 2024 to December 31, 2025 Common stock issued for RSUs vested Exercise of stock options Share repurchase Excise tax on net share repurchase
From July 1, 2025 to September 30, 2025 Exercise of stock options Share repurchase Excise tax on net share repurchase
From April 1, 2025 to June 30, 2025 Exercise of stock options
From January 1, 2025 to March 31, 2025 Common stock issued for RSUs vested Exercise of stock options
From December 31, 2023 to December 31, 2024 Common stock issued for RSUs vested Exercise of stock options Share repurchase Excise tax on net share repurchase
From July 1, 2024 to September 30, 2024 Exercise of stock options Share repurchase Excise tax on net share repurchase
From April 1, 2024 to June 30, 2024 Exercise of stock options
From January 1, 2024 to March 31, 2024 Common stock issued for RSUs vested Exercise of stock options
From December 31, 2022 to December 31, 2023 Common stock issued for RSUs vested Exercise of stock options
From July 1, 2023 to September 30, 2023 Exercise of stock options
from April 1, 2023 to June 30, 2023 Exercise of stock options
From January 1, 2023 to March 31, 2023 Common stock issued for RSUs vested Exercise of stock options
From December 31, 2021 to December 31, 2022 Shares issued under ESPP Common stock issued for RSUs vested Exercise of stock options
From July 1, 2022 to September 30, 2022 Shares issued under employee stock purchase plan (ESPP)
From April 1, 2022 to June 30, 2022 Exercise of stock options
From January 1, 2022 to March 31, 2022 Common stock issued for RSUs vested Exercise of stock options
From December 31, 2020 to December 31, 2021 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
From July 1, 2021 to September 30, 2021 Exercise of stock options
From April 1, 2021 to June 30, 2021 Exercise of stock options
from January 1, 2021 to March 31, 2021 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
From December 31,2019 to December 31,2020 Shares issued under employee stock purchase plan Common stock issued for RSUs vested Exercise of stock options
From July 1, 2020 to September 30, 2020 Shares issued under employee stock purchase plan
From April 1, 2020 to June 30, 2020 Exercise of stock options
From January 1, 2020 to March 31, 2020 Common stock issued for RSUs vested
From December 31, 2018 to December 31, 2019 Common stock issued upon RSU vesting Exercise of stock options
from January 1, 2019 to September 30, 2019 Common stock issued upon RSU vesting Exercise of stock options
from April 1, 2019 to June 30, 2019 Common stock issued upon RSU vesting
from January 1, 2019 to March 31, 2019 Exercise of stock options
from December 31, 2017 to December 31, 2018 Exercise of stock options
from December 31, 2016 to December 31, 2017 Shares issued under employee stock purchase plan Exercise of stock options Shares issued upon expiration of warrants Repurchase of shares
from December 31, 2015 to December 31, 2016 Conversion of 2016 convertible notes Exercise of stock options Shares issued upon expiration of warrants Repurchase of shares
from December 31, 2014 to December 31, 2015 Shares issued under employee stock purchase plan Conversion of 2016 convertible notes Exercise of stock options Repurchase of shares
from December 31, 2013 to December 31, 2014 Shares issued under employee stock purchase plan Conversion of 2016 convertible notes Exercise of stock options Repurchase of shares
from December 31, 2012 to December 31, 2013 Shares issued under employee stock purchase plan Exercise of stock options Repurchase of shares
from December 31, 2011 to December 31, 2012 Exercise of stock options Repurchase of shares
from Dec 31,2010 to Dec 31,2011 Conversion of 2011 convertible notes and exercise of convertible note hedge Exercise of stock options Shares received as part of Medicomp sale Share repurchase
from dec 31 2009 to dec 31 2010 Exercise of stock options Stock issued in connection with conversion of Convertible Senior Notes
from December 31,2008 to December 31,2009 Issuance of stock dividend Exercise of stock options the two-for-one split of our common stock on September 22, 2009.
from December 31,2007 to December 31,2008 Exercise of stock options Issuance of treasury stock
from December 31,2006 to December 31,2007 Exercise of stock options Treasury stock repurchases
from December 31,2005 to December 31,2006 Exercise of stock options Treasury stock repurchases
from December 31,2004 to December 31,2005 Exercise of stock options
from December 31,2003 to December 31,2004 Exercise of stock options Settlement of shares due to sellers of Medicomp
from December 31,2002 to December 31,2003 Exercise of stock options
from December 31,2001 to December 31,2002 Settlement of escrow items with sellers of Cooke Pharma Exercise of stock options
from December 31,2000 to December 31,2001 Stock issued in exchange for services Exercise of stock options Purchases of treasury stock
from December 31, 1999 to December 31,2000 Issuance of common stock through private sales Stock issued for acquisition of Cooke Pharma, Inc. Stock issued for acquisition of Medicomp, Inc. and Telemedical Procedures, LLC Stock issued for investment in Synergy Pharmaceuticals, Inc. Adjustment to SynQuest, Inc. escrow Stock issued for exclusive license agreement Stock issued in exchange for services Exercise of stock options Purchases of treasury stock
from December 31, 1998 to December 31, 1999 Issuance of common stock through private sales Issuance of common stock through initial public offering Issuance of common stock to underwriters for over-allotment shares Stock issued for exclusive license agreement Stock issued for acquisition of SynQuest, Inc.
from December 31, 1997 to December 31, 1998 Issuance of common stock Stock issued in exchange for services Stock issued for exclusive license agreement