主要股东
注:以下部分股东代表特定权益共同体,直接或间接持有上市公司股份
| 序号 | 股东名称 | 是否机构 | 持股数(股) | 持股比例 | 持股变动数(股) | 持股数变动比例 | 投票权比例 |
|---|---|---|---|---|---|---|---|
| 1 | Entities affiliated with Versant Ventures | 是 | 361.62万 | 10.00% | 新增 | 新增 | -- |
| 2 | TPG Biotechnology Partners II, L.P | 是 | 355.19万 | 9.90% | 新增 | 新增 | -- |
| 3 | ACUTA CAPITAL PARTNERS, LLC | 是 | 329.51万 | 9.10% | 新增 | 新增 | -- |
| 4 | Entities affiliated with Domain Partners | 是 | 281.71万 | 7.80% | 新增 | 新增 | -- |
| 5 | EVENTIDE ASSET MANAGEMENT, LLC | 是 | 213.35万 | 5.90% | 新增 | 新增 | -- |
| 6 | Cannell Capital, LLC | 是 | 191.26万 | 5.30% | 新增 | 新增 | -- |
| 7 | 贝莱德集团公司 | 是 | 184.30万 | 5.10% | 新增 | 新增 | -- |
内部人交易
| 日期 | 股东名称 | 变动股数(万股) | 交易后持股数量(万股) | 交易价格 | 是否直接持有 | 内部人类型 |
|---|---|---|---|---|---|---|
| 2025-12-05 | EASTHAM KARIN |
|
2.36 | 7.94 | 是 | -- |
| 2025-12-05 | EASTHAM KARIN |
|
3.36 | 7.60 | 是 | -- |
| 2025-12-05 | EASTHAM KARIN |
|
2.72 | 44.52 | 是 | -- |
| 2025-12-05 | EASTHAM KARIN |
|
1.44 | 45.84 | 是 | -- |
| 2025-12-05 | EASTHAM KARIN |
|
1.36 | 46.59 | 是 | -- |
| 2025-12-02 | Stapley Marc |
|
32.63 | 46.16 | 是 | Chief Executive Officer |
| 2025-12-02 | Stapley Marc |
|
32.18 | 46.90 | 是 | Chief Executive Officer |
| 2025-12-02 | Stapley Marc |
|
31.86 | 47.35 | 是 | Chief Executive Officer |
| 2025-12-02 | Wygant Jonathan |
|
3.74 | 46.16 | 是 | VP, Chief Accounting Officer |
| 2025-12-02 | Febbo Phillip G. |
|
8.95 | 46.16 | 是 | Chief Scientific & Med Officer |
| 2025-12-02 | Chambers Rebecca |
|
12.28 | 46.16 | 是 | Chief Financial Officer |
| 2025-12-02 | Chambers Rebecca |
|
11.42 | 46.61 | 是 | Chief Financial Officer |
| 2025-12-02 | Chambers Rebecca |
|
10.95 | 47.25 | 是 | Chief Financial Officer |
| 2025-12-02 | McGuire Annie |
|
7.99 | 46.16 | 是 | SVP, General Counsel |
| 2025-12-02 | McGuire Annie |
|
7.92 | 47.10 | 是 | SVP, General Counsel |
| 2025-12-02 | McGuire Annie |
|
7.85 | 47.51 | 是 | SVP, General Counsel |
| 2025-12-02 | Leite John |
|
8.34 | 46.16 | 是 | Chief Commercial Officer-CLIA |
| 2025-12-02 | Leite John |
|
8.21 | 47.51 | 是 | Chief Commercial Officer-CLIA |
| 2025-11-25 | JONES EVAN/ FA |
|
2.94 | 50.25 | 是 | -- |
| 2025-11-25 | Leite John |
|
8.63 | 50.00 | 是 | Chief Commercial Officer-CLIA |
| 2025-11-20 | Holstein Jens |
|
2.72 | 43.21 | 是 | -- |
| 2025-11-20 | Holstein Jens |
|
3.57 | 40.95 | 是 | -- |
| 2025-11-20 | Holstein Jens |
|
2.87 | 42.48 | 是 | -- |
| 2025-11-07 | Wygant Jonathan |
|
4.38 | 40.21 | 是 | VP, Chief Accounting Officer |
| 2025-11-07 | Wygant Jonathan |
|
3.87 | 42.33 | 是 | VP, Chief Accounting Officer |
| 2025-11-05 | EASTHAM KARIN |
|
1.36 | 40.02 | 是 | -- |
| 2025-11-05 | Chambers Rebecca |
|
12.62 | 41.00 | 是 | Chief Financial Officer |
| 2025-11-05 | McGuire Annie |
|
8.30 | 40.00 | 是 | SVP, General Counsel |
| 2025-11-05 | JONES EVAN/ FA |
|
5.37 | 5.28 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
6.37 | 7.94 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
7.37 | 7.60 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
7.33 | 41.74 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
7.21 | 43.03 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
6.13 | 43.80 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
5.54 | 45.07 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
3.11 | 45.73 | 是 | -- |
| 2025-11-05 | JONES EVAN/ FA |
|
3.05 | 46.38 | 是 | -- |
| 2025-10-28 | Wygant Jonathan |
|
4.97 | 0.00 | 是 | VP, Chief Accounting Officer |
| 2025-10-06 | Febbo Phillip G. |
|
9.24 | 36.02 | 是 | Chief Scientific & Med Officer |
| 2025-10-01 | McGuire Annie |
|
8.94 | 35.00 | 是 | SVP, General Counsel |
| 2025-10-01 | EPSTEIN ROBERT S |
|
8.39 | 7.94 | 是 | -- |
| 2025-10-01 | EPSTEIN ROBERT S |
|
6.24 | 35.08 | 是 | -- |
| 2025-10-01 | Leite John |
|
8.91 | 35.00 | 是 | Chief Commercial Officer-CLIA |
| 2025-09-19 | McGuire Annie |
|
9.16 | 33.69 | 是 | SVP, General Counsel |
| 2025-09-04 | Stapley Marc |
|
33.42 | 30.41 | 是 | Chief Executive Officer |
| 2025-09-02 | Wygant Jonathan |
|
4.68 | 30.11 | 是 | VP, Chief Accounting Officer |
| 2025-09-02 | Leite John |
|
9.16 | 30.11 | 是 | Chief Commercial Officer-CLIA |
| 2025-09-02 | Febbo Phillip G. |
|
10.08 | 30.11 | 是 | Chief Scientific & Med Officer |
| 2025-09-02 | Stapley Marc |
|
34.19 | 30.11 | 是 | Chief Executive Officer |
| 2025-09-02 | McGuire Annie |
|
9.39 | 30.11 | 是 | SVP, General Counsel |
| 2025-09-02 | Chambers Rebecca |
|
13.32 | 30.11 | 是 | Chief Financial Officer |
| 2025-06-18 | JONES EVAN/ FA |
|
4.37 | 0.00 | 是 | -- |
| 2025-06-18 | Shafer David Brent |
|
2.58 | 0.00 | 是 | -- |
| 2025-06-18 | Bhanji Muna |
|
3.93 | 0.00 | 是 | -- |
| 2025-06-18 | Barr Eliav |
|
5.12 | 0.00 | 是 | -- |
| 2025-06-18 | Miller Thomas F. |
|
2.58 | 0.00 | 是 | -- |
| 2025-06-18 | EPSTEIN ROBERT S |
|
7.39 | 0.00 | 是 | -- |
| 2025-06-18 | EASTHAM KARIN |
|
2.32 | 0.00 | 是 | -- |
| 2025-06-18 | Holstein Jens |
|
3.72 | 0.00 | 是 | -- |
| 2025-06-13 | EASTHAM KARIN |
|
1.39 | 26.66 | 是 | -- |
| 2025-06-13 | Bhanji Muna |
|
3.00 | 26.67 | 是 | -- |
| 2025-06-04 | Leite John |
|
9.45 | 27.20 | 是 | Chief Commercial Officer-CLIA |
| 2025-06-02 | Febbo Phillip G. |
|
10.37 | 26.74 | 是 | Chief Scientific & Med Officer |
| 2025-06-02 | Stapley Marc |
|
34.92 | 26.74 | 是 | Chief Executive Officer |
| 2025-06-02 | Wygant Jonathan |
|
4.79 | 26.74 | 是 | VP, Chief Accounting Officer |
| 2025-06-02 | Chambers Rebecca |
|
13.85 | 26.74 | 是 | Chief Financial Officer |
| 2025-06-02 | McGuire Annie |
|
9.70 | 26.74 | 是 | SVP, General Counsel |
| 2025-06-02 | Leite John |
|
9.73 | 26.74 | 是 | Chief Commercial Officer-CLIA |
| 2025-03-06 | Stapley Marc |
|
35.86 | 0.00 | 是 | Chief Executive Officer |
| 2025-03-06 | Wygant Jonathan |
|
4.98 | 0.00 | 是 | VP, Chief Accounting Officer |
| 2025-03-06 | Febbo Phillip G. |
|
10.67 | 0.00 | 是 | Chief Scientific & Med Officer |
| 2025-03-06 | Chambers Rebecca |
|
14.39 | 0.00 | 是 | Chief Financial Officer |
| 2025-03-06 | McGuire Annie |
|
10.05 | 0.00 | 是 | SVP, General Counsel |
| 2025-03-06 | Leite John |
|
10.77 | 0.00 | 是 | Chief Commercial Officer-CLIA |
| 2025-03-06 | Leite John |
|
10.53 | 31.04 | 是 | Chief Commercial Officer-CLIA |
| 2025-03-06 | Leite John |
|
10.02 | 31.96 | 是 | Chief Commercial Officer-CLIA |
| 2025-03-04 | Stapley Marc |
|
29.25 | 32.82 | 是 | Chief Executive Officer |
| 2025-03-04 | Stapley Marc |
|
26.91 | 33.91 | 是 | Chief Executive Officer |
| 2025-03-04 | Stapley Marc |
|
26.80 | 34.37 | 是 | Chief Executive Officer |
| 2025-03-04 | Febbo Phillip G. |
|
8.61 | 32.86 | 是 | Chief Scientific & Med Officer |
| 2025-03-04 | Febbo Phillip G. |
|
8.25 | 33.95 | 是 | Chief Scientific & Med Officer |
| 2025-03-04 | McGuire Annie |
|
7.03 | 33.69 | 是 | SVP, General Counsel |
| 2025-03-02 | Wygant Jonathan |
|
3.65 | 34.76 | 是 | VP, Chief Accounting Officer |
| 2025-02-27 | Febbo Phillip G. |
|
11.30 | 0.00 | 是 | Chief Scientific & Med Officer |
| 2025-02-27 | Febbo Phillip G. |
|
9.73 | 33.84 | 是 | Chief Scientific & Med Officer |
| 2025-02-27 | Febbo Phillip G. |
|
9.06 | 34.76 | 是 | Chief Scientific & Med Officer |
| 2025-02-27 | Leite John |
|
8.48 | 0.00 | 是 | Chief Commercial Officer-CLIA |
| 2025-02-27 | Leite John |
|
7.91 | 33.84 | 是 | Chief Commercial Officer-CLIA |
| 2025-02-27 | Leite John |
|
7.14 | 34.76 | 是 | Chief Commercial Officer-CLIA |
| 2025-02-27 | Stapley Marc |
|
37.53 | 0.00 | 是 | Chief Executive Officer |
| 2025-02-27 | Stapley Marc |
|
34.11 | 33.84 | 是 | Chief Executive Officer |
| 2025-02-27 | Stapley Marc |
|
32.07 | 34.76 | 是 | Chief Executive Officer |
| 2025-02-27 | McGuire Annie |
|
8.67 | 0.00 | 是 | SVP, General Counsel |
| 2025-02-27 | McGuire Annie |
|
7.97 | 33.84 | 是 | SVP, General Counsel |
| 2025-02-27 | McGuire Annie |
|
7.15 | 34.76 | 是 | SVP, General Counsel |
| 2025-02-27 | Chambers Rebecca |
|
13.67 | 0.00 | 是 | Chief Financial Officer |
| 2025-02-27 | Chambers Rebecca |
|
12.48 | 33.84 | 是 | Chief Financial Officer |
| 2025-02-27 | Chambers Rebecca |
|
11.37 | 34.76 | 是 | Chief Financial Officer |
| 2025-02-03 | Chambers Rebecca |
|
11.35 | 43.85 | 是 | Chief Financial Officer |
| 2025-01-06 | EPSTEIN ROBERT S |
|
6.46 | 8.04 | 是 | -- |
| 2025-01-02 | EASTHAM KARIN |
|
2.85 | 5.28 | 是 | -- |
| 2025-01-02 | EASTHAM KARIN |
|
2.32 | 40.12 | 是 | -- |
| 2025-01-02 | EASTHAM KARIN |
|
1.85 | 40.50 | 是 | -- |
| 2024-12-13 | Stapley Marc |
|
30.77 | 43.37 | 是 | Chief Executive Officer |
| 2024-12-13 | Stapley Marc |
|
30.73 | 44.14 | 是 | Chief Executive Officer |
| 2024-12-04 | Febbo Phillip G. |
|
8.24 | 44.09 | 是 | Chief Scientific & Med Officer |
| 2024-12-04 | McGuire Annie |
|
7.29 | 44.02 | 是 | SVP, General Counsel |
| 2024-12-02 | Stapley Marc |
|
31.29 | 44.12 | 是 | Chief Executive Officer |
| 2024-12-02 | Wygant Jonathan |
|
4.12 | 44.12 | 是 | VP, Chief Accounting Officer |
| 2024-12-02 | Wygant Jonathan |
|
4.03 | 43.36 | 是 | VP, Chief Accounting Officer |
| 2024-12-02 | Febbo Phillip G. |
|
8.63 | 44.12 | 是 | Chief Scientific & Med Officer |
| 2024-12-02 | Chambers Rebecca |
|
12.10 | 44.12 | 是 | Chief Financial Officer |
| 2024-12-02 | Chambers Rebecca |
|
11.40 | 43.23 | 是 | Chief Financial Officer |
| 2024-12-02 | McGuire Annie |
|
9.16 | 44.12 | 是 | SVP, General Counsel |
| 2024-12-02 | Leite John |
|
7.49 | 44.12 | 是 | Chief Commercial Officer-CLIA |
| 2024-12-02 | Leite John |
|
7.38 | 43.25 | 是 | Chief Commercial Officer-CLIA |
| 2024-11-27 | Wygant Jonathan |
|
4.23 | 42.89 | 是 | VP, Chief Accounting Officer |
| 2024-11-19 | EASTHAM KARIN |
|
3.16 | 36.77 | 是 | -- |
| 2024-11-19 | EASTHAM KARIN |
|
2.86 | 37.77 | 是 | -- |
| 2024-11-19 | EASTHAM KARIN |
|
1.85 | 38.76 | 是 | -- |
| 2024-11-12 | EPSTEIN ROBERT S |
|
5.96 | 8.04 | 是 | -- |
| 2024-11-12 | EPSTEIN ROBERT S |
|
4.46 | 38.32 | 是 | -- |
| 2024-11-12 | Chambers Rebecca |
|
12.45 | 38.34 | 是 | Chief Financial Officer |
| 2024-09-04 | Leite John |
|
7.62 | 29.78 | 是 | Chief Commercial Officer-CLIA |
| 2024-09-03 | Miller Thomas F. |
|
1.65 | 0.00 | 是 | -- |
| 2024-09-03 | Shafer David Brent |
|
1.65 | 0.00 | 是 | -- |
| 2024-09-02 | Leite John |
|
8.17 | 31.55 | 是 | Chief Commercial Officer-CLIA |
| 2024-09-02 | Stapley Marc |
|
31.87 | 31.55 | 是 | Chief Executive Officer |
| 2024-09-02 | Wygant Jonathan |
|
4.73 | 31.55 | 是 | VP, Chief Accounting Officer |
| 2024-09-02 | McGuire Annie |
|
9.35 | 31.55 | 是 | SVP, General Counsel |
| 2024-09-02 | Chambers Rebecca |
|
13.98 | 31.55 | 是 | Chief Financial Officer |
| 2024-08-12 | JONES EVAN/ FA |
|
5.48 | 10.41 | 是 | -- |
| 2024-08-12 | JONES EVAN/ FA |
|
5.19 | 31.19 | 是 | -- |
| 2024-08-12 | JONES EVAN/ FA |
|
3.50 | 32.36 | 是 | -- |
| 2024-08-12 | JONES EVAN/ FA |
|
3.43 | 32.77 | 是 | -- |
| 2024-08-09 | JONES EVAN/ FA |
|
4.74 | 10.41 | 是 | -- |
| 2024-08-09 | JONES EVAN/ FA |
|
4.64 | 30.03 | 是 | -- |
| 2024-08-07 | JONES EVAN/ FA |
|
5.03 | 10.41 | 是 | -- |
| 2024-08-07 | JONES EVAN/ FA |
|
4.71 | 30.32 | 是 | -- |
| 2024-08-07 | Holstein Jens |
|
3.04 | 28.00 | 是 | -- |
| 2024-08-07 | Holstein Jens |
|
2.79 | 30.00 | 是 | -- |
| 2024-07-16 | Holstein Jens |
|
3.54 | 24.00 | 是 | -- |
| 2024-07-16 | Holstein Jens |
|
3.29 | 25.00 | 是 | -- |
| 2024-07-16 | Leite John |
|
8.30 | 25.00 | 是 | Chief Commercial Officer-CLIA |
| 2024-07-16 | EASTHAM KARIN |
|
3.32 | 25.00 | 是 | -- |
| 2024-06-13 | EPSTEIN ROBERT S |
|
4.46 | 0.00 | 是 | -- |
| 2024-06-13 | JONES EVAN/ FA |
|
4.91 | 0.00 | 是 | -- |
| 2024-06-13 | Holstein Jens |
|
3.79 | 0.00 | 是 | -- |
| 2024-06-13 | Bhanji Muna |
|
3.46 | 0.00 | 是 | -- |
| 2024-06-13 | Barr Eliav |
|
4.19 | 0.00 | 是 | -- |
| 2024-06-13 | EASTHAM KARIN |
|
4.07 | 0.00 | 是 | -- |
| 2024-06-11 | EASTHAM KARIN |
|
2.93 | 20.59 | 是 | -- |
| 2024-06-10 | Bhanji Muna |
|
2.31 | 20.32 | 是 | -- |
| 2024-06-07 | EASTHAM KARIN |
|
3.56 | 10.41 | 是 | -- |
| 2024-06-07 | EASTHAM KARIN |
|
3.31 | 20.97 | 是 | -- |
| 2024-06-02 | Stapley Marc |
|
32.40 | 20.75 | 是 | Chief Executive Officer |
| 2024-06-02 | Chambers Rebecca |
|
14.32 | 20.75 | 是 | Chief Financial Officer |
| 2024-06-02 | McGuire Annie |
|
9.54 | 20.75 | 是 | SVP, General Counsel |
| 2024-06-02 | Leite John |
|
8.42 | 20.75 | 是 | Chief Commercial Officer-CLIA |
| 2024-06-02 | Wygant Jonathan |
|
4.80 | 20.75 | 是 | VP, Chief Accounting Officer |
| 2024-05-28 | Bhanji Muna |
|
2.70 | 21.00 | 是 | -- |
| 2024-04-01 | EASTHAM KARIN |
|
4.31 | 13.19 | 是 | -- |
| 2024-04-01 | EASTHAM KARIN |
|
3.31 | 21.65 | 是 | -- |
| 2024-03-15 | Stapley Marc |
|
33.57 | 0.00 | 是 | Chief Executive Officer |
| 2024-03-15 | Stapley Marc |
|
32.97 | 21.10 | 是 | Chief Executive Officer |
| 2024-03-15 | Chambers Rebecca |
|
14.89 | 0.00 | 是 | Chief Financial Officer |
| 2024-03-15 | Chambers Rebecca |
|
14.67 | 21.10 | 是 | Chief Financial Officer |
| 2024-03-06 | Stapley Marc |
|
32.39 | 0.00 | 是 | Chief Executive Officer |
| 2024-03-06 | Wygant Jonathan |
|
4.91 | 0.00 | 是 | VP, Chief Accounting Officer |
| 2024-03-06 | McGuire Annie |
|
9.73 | 0.00 | 是 | SVP, General Counsel |
| 2024-03-06 | Leite John |
|
8.56 | 0.00 | 是 | Chief Commercial Officer-CLIA |
| 2024-03-06 | Febbo Phillip G. |
|
9.31 | 0.00 | 是 | Chief Scientific & Med Officer |
| 2024-03-06 | Chambers Rebecca |
|
14.46 | 0.00 | 是 | Chief Financial Officer |
| 2024-03-02 | McGuire Annie |
|
4.74 | 24.00 | 是 | SVP, General Counsel |
| 2024-03-02 | Wygant Jonathan |
|
2.51 | 24.00 | 是 | VP, Chief Accounting Officer |
| 2024-03-02 | Chambers Rebecca |
|
8.47 | 24.00 | 是 | Chief Financial Officer |
| 2024-03-02 | Stapley Marc |
|
20.92 | 24.00 | 是 | Chief Executive Officer |
| 2024-03-02 | Leite John |
|
3.57 | 24.00 | 是 | Chief Commercial Officer-CLIA |
| 2024-03-01 | JONES EVAN/ FA |
|
4.76 | 13.19 | 是 | -- |
| 2024-03-01 | JONES EVAN/ FA |
|
3.76 | 24.36 | 是 | -- |