换肤

主营介绍

主营构成分析

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单位(%) 单位(万元)
注:通常在中报、年报时披露 
业务名称 营业收入(元) 收入比例 营业成本(元) 成本比例 利润比例 毛利率
按行业 科研服务业 2.89亿 71.63% 5898.82万 46.29% 83.33% 79.59%
检测试剂生产 1.14亿 28.26% 6742.60万 52.91% 16.88% 40.86%
化妆品制造业 45.28万 0.11% 101.83万 0.80% -0.20% -124.88%
按产品 细胞检测制备及存储 2.34亿 58.03% 4122.93万 32.35% 69.88% 82.39%
检测试剂 1.14亿 28.26% 6742.60万 52.91% 16.88% 40.86%
基因检测 4013.97万 9.95% 1075.45万 8.44% 10.64% 73.21%
细胞培养 904.04万 2.24% 430.40万 3.38% 1.72% 52.39%
免疫细胞 560.57万 1.39% 240.59万 1.89% 1.16% 57.08%
化妆品 45.28万 0.11% 101.83万 0.80% -0.20% -124.88%
细胞因子培养液 10.96万 0.03% 29.44万 0.23% -0.07% -168.57%
按地区 天津 1.41亿 35.06% - - - -
上海 1.14亿 28.19% - - - -
云南 2324.08万 5.76% - - - -
浙江 2018.34万 5.00% - - - -
海南 1685.13万 4.18% - - - -
江苏 1202.41万 2.98% - - - -
重庆 1189.62万 2.95% - - - -
辽宁 929.44万 2.30% - - - -
河南 903.23万 2.24% - - - -
山西 742.17万 1.84% - - - -
吉林 698.84万 1.73% - - - -
黑龙江 689.02万 1.71% - - - -
陕西 635.11万 1.57% - - - -
江西 582.26万 1.44% - - - -
福建 525.62万 1.30% - - - -
贵州 380.04万 0.94% - - - -
甘肃 266.56万 0.66% - - - -
安徽 57.72万 0.14% - - - -

主要客户及供应商

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前5大客户:共销售了4570.76万元,占营业收入的14.86%
  • 上海中宇纺织有限公司
  • 江阴市青阳镇针织绒厂
  • 江阴市沪青平绒有限公司
  • 江阴市红嘉印染有限公司
  • 常州市武进丽华实业有限公司
  • 其他
客户名称 销售额(元) 占比
上海中宇纺织有限公司
1521.99万 4.95%
江阴市青阳镇针织绒厂
1173.55万 3.81%
江阴市沪青平绒有限公司
1058.43万 3.44%
江阴市红嘉印染有限公司
527.95万 1.72%
常州市武进丽华实业有限公司
288.84万 0.94%

董事会经营评述

  一、经营情况的讨论与分析
  报告期内,公司实现营业收入4.08亿元,比上年同期增长12.60%;实现净利润1561.08万元,比上年同期下降37.82%、实现归属于上市公司股东的净利润838.80万元,比上年同期下降47.56%、实现归属于上市公司股东的扣除非经常性损益的净利润-903.07万元,比上年同期下降130.77%,公司利润下降的主要影响因素有:1、报告期公司子公司上海执诚公司开展医院大打包业务,前期市场投入较大,及朗道产品收入较上年同期相比下降,导致上海执诚公司净利润较上年同期相比减少1406万元;2、报告期公司对北京泛生子基因科技有限公司、天津百乐思生物科技发展有限公司采用... 查看全部▼

  一、经营情况的讨论与分析
  报告期内,公司实现营业收入4.08亿元,比上年同期增长12.60%;实现净利润1561.08万元,比上年同期下降37.82%、实现归属于上市公司股东的净利润838.80万元,比上年同期下降47.56%、实现归属于上市公司股东的扣除非经常性损益的净利润-903.07万元,比上年同期下降130.77%,公司利润下降的主要影响因素有:1、报告期公司子公司上海执诚公司开展医院大打包业务,前期市场投入较大,及朗道产品收入较上年同期相比下降,导致上海执诚公司净利润较上年同期相比减少1406万元;2、报告期公司对北京泛生子基因科技有限公司、天津百乐思生物科技发展有限公司采用权益法核算,共确认投资损失1033万元;3、报告期海外公司研发及运营投入与上年同期相比增加729万元。3、报告期海外公司研发及运营投入与上年同期相比增加729万元。
  报告期,公司主要开展了以下工作:
  (一)事业部间协同发展,促进业绩持续增长
  从2016年实行事业部管理以来,新生儿、成人和基因三大事业部自主经营、独立核算,强化
  学检验所加强医院院线合作,建立中源协和肿瘤基因组与药物数据库平台;成人事业部:成人免疫细胞存储等健康管理业务快速增长,确立了间充质干细胞的临床科研合作标准,同时建立健康管家团队,从单一的提供产品向“产品+服务”的业务模式转化,将完善客户服务列为工作重点。
  (二)业务聚焦精耕细作,拓展基因产品线
  积极拓展基因检测产品线,报告期研发完成多个新产品,包括大健康系列的肌肤基因检测项目、运动基因检测项目等;肿瘤检测系列的肺癌靶向超敏检测项目、结直肠癌靶向超敏检测项目、隆通-肿瘤基因全项518检测项目等。基因事业部业绩稳步提升,其中唐氏综合征筛查销售额持续快速增长,肿瘤线产品逐渐完善,销售额增幅显著,体现了精准的产品定位,强大的研发实力和卓越的渠道能力。
  (三)继续加强媒介管理,重视品牌建设
  公司与各类主流媒体建立良好合作关系,同时充分利用自媒体优势,围绕公司乃至行业重大
  (四)强化采购管理,优化生产运营
  为有效达成采购管理的规范化、集约化,实现公司业务平台的资源整合,提高管理效率和成本优势,报告期公司取消生产运营中心,设立采购管理中心,规范公司采购管理体系,完善物流仓储管理,物料成本大幅降低。
  (五)加强人才建设,提高管理效率
  持续深入开展三级入职培训体系,使得新员工能更快融入企业,有效发挥自身价值。同时,举办各种形式的业务培训,提高员工专业水平和技术能力,助力企业发展。另外,首届中源协和人才培养项目--“黑石计划”为公司储备了大量中高层人才,各分子公司之间进行充分的经验交流,建立更加紧密而高效的深度合作关系,为中源协和全国协同发展奠定了良好基础。
  二、报告期内公司所从事的主要业务、经营模式及行业情况说明:
  (一)公司的主要业务
  报告期内公司所从事的主要业务为细胞制备和存储服务、基因检测、体外诊断试剂的销售、美容抗衰老等。主要产品包括脐带血造血干细胞、脐带间充质干细胞、胎盘亚全能干细胞、脂肪干细胞及免疫细胞等的制备与存储服务;儿童基因、无创产前基因、肿瘤及心血管基因、成人易感基因等基因检测服务,生化诊断试剂的生产和销售、美容和化妆产品的生产和销售等。
  脐带血造血干细胞,可通过其多向分化等能力在血液系统等疾病的治疗上发挥重要作用;脐带间充质干细胞和胎盘亚全能干细胞则通过其旁分泌和免疫调节等作用,在组织器官的修复、免疫调节以及人体保健等方面有着重要的医疗作用;利用基因检测技术可进行胎儿染色体数目异常疾病的检测,可提前获知疾病遗传信息、易患疾病,以及了解儿童的天赋潜能等,从而实现早检测、早预防,降低疾病造成的损害;诊断试剂可以为民众疾病预防、诊断、治疗监测、愈后观察、健康状态的判断提出医学参考数据;美容和化妆产品,覆盖洁面、爽肤、润肤、精华、面膜、护肤等丰富的产品线。
  (二)经营模式
  为有效支撑“细胞+基因”双核驱动的战略布局,强化战略统筹、资源调配、风险控制、服务支持的功能定位,明确各业务板块作为经营管理和利润实现的主体地位,激发“6+1”的全产业链发展模式的潜力和活力,建立与公司未来整体产业及业务布局相适应的组织发展平台。同时,随着事业部+直管公司的经营模式的实施,通过深化业务聚焦、整合资源、适度分权,各事业部和直管公司成为真正的业务开拓领导者,实现股东利益的最大化。
  1、新生儿事业部
  负责为客户提供包括脐带血造血干细胞、脐带间充质干细胞、胎盘亚全能干细胞等存储服务。
  细胞存储业务主要采用自营的营销模式,为客户提供安全、高效的细胞存储技术服务。
  2、基因事业部
  基因事业部为合作医院和健康管理机构等提供无创产前基因、新生儿耳聋检测、健康基因和天赋基因检测、高精度成人肿瘤易感基因检测、无创肿瘤精准用药检测、临床生化检测试剂等业务。相关业务主要采用自营和代理两种营销模式:通过与医院、合作机构签订合作协议等方式建立销售渠道,提供相关产品销售及基因检测技术服务。
  3、成人事业部
  成人事业部业务主要包括免疫细胞存储、间充质干细胞存储两大业务线条,采用自营和代理等营销模式进行产品的销售,通过客户存储、全国新生儿业务平台、各区域代理商、高净值客户平台、美容整形机构等销售渠道,推动成人细胞存储业务。
  4、美业
  中源诗丹赛尔(天津)化妆品有限公司的“诗丹赛尔”商标获得天津市著名商标称号。产品有微分子透明质酸系列、青春源等系列产品,由直管公司负责产品的市场推广与销售,采用自营和代理等多种营销模式。
  5、药业
  中源药业有限公司主要负责药物的研发,药业的药品注册部和医学事务部承载公司旗下药物研发公司的干细胞药物、生物制品等的注册和临床试验事务,为药物及早进入临床试验和上市提供有力的支持。
  (三)主要业绩驱动因素
  报告期公司主要业绩驱动因素为:
  1、加大对基因检测业务的市场投入,开拓肿瘤线等新的基因检测领域,收入较上年同期增长44.53%;
  2、受二胎政策、销售模式创新等因素影响,细胞检测制备及存储业务收入较上年同期相比增加21.22%。
  (四)行业情况
  公司以细胞和基因工程为主营业务,属于国家重点扶植的战略性新兴产业,目前处于快速发展和整合布局阶段。具体情况为,公司的新生儿干细胞资源存储、临床生化检测试剂等是目前发展最为成熟的产业,已在全国包括天津、黑龙江、吉林、辽宁、山西、陕西、河南、安徽、浙江、江西、江苏、上海、福建、重庆、贵州、云南、海南及甘肃建立了细胞资源库;基因检测、成人免疫细胞业务、干细胞技术属于相对较新兴的产业,其技术更新快,发展潜力巨大;公司的抗衰老业务借助公司细胞和基因的技术优势,具有良好的发展前景。
  公司将继续坚持“细胞+基因”双核驱动的发展战略,布局公司“6+1”全产业链协同发展的业务模式,保持公司在行业中的领先地位。
  我国细胞与基因产业主要分为细胞产业和基因检测产业。其中细胞产业可分为细胞存储、细胞技术研发和细胞临床治疗,其中以干细胞和免疫细胞为主。基因检测产业可分为基因检测的仪器和试剂、检测技术研发和服务、大数据库构建与分析。
  1、国内干细胞领域政策频出,2015年,《干细胞临床研究管理办法(试行)》和《干细胞
  制剂质量控制及临床前研究指导原则(试行)》两大政策先后出台,为干细胞产业规范化发展奠定了良好的政策基础。2016年陆续发布多项政策文件,包括《“十三五”国家科技创新规划》等,多次强调干细胞与再生医学的重要地位。2016年10月24日,卫计委、CFDA公布首批通过备案的30家干细胞临床研究机构,并且已于2017年4月启动第二批干细胞临床研究机构备案,推动了干细胞临床研究的发展。
  免疫细胞方面,2016年12月中旬,CFDA药品审评中心对外发布了《细胞制品研究与评价技术指导原则》(征求意见稿),为国内细胞治疗行业制定了详细的一般性与通用性指导原则,将促进免疫细胞产业的发展。
  基因产业方面,2017年1月,国家发改委正式印发了《“十三五”生物产业发展规划》,明确提出了基因检测能力覆盖50%以上出生人口的目标,强调了以个人基因组信息为基础,结合蛋白质组、代谢组等相关内环境信息,整合不同数据层面的生物学信息库,利用基因测序、影像、大数据分析等手段,在产前胎儿罕见病筛查、肿瘤、遗传性疾病等方面实现精准的预防、诊断和治疗。
  随着国家支持政策的陆续出台,近年来,国内各省份陆续发布政策支持基因检测技术的应用,鼓励开展和推广遗传病基因检测、开展基因检测试点、大力推广个性化医疗、探讨基因检测的收费体制等。
  整体上,国家对干细胞与再生医学、免疫细胞、基因检测的政策支持力度持续加大。2017年6月,国家科技部、国家卫生计生委、体育总局、食品药品监管总局、国家中医药管理局、中央军委后勤保障部等六部委联合印发《“十三五”卫生与健康科技创新专项规划》。规划中明确要求加强干细胞和再生医学、免疫治疗、基因治疗、细胞治疗等关键技术研究,加快生物治疗前沿技术的临床应用,创新治疗技术,提高临床救治水平。为干细胞、免疫细胞、基因检测等方面的长远发展提供了更为坚实的政策基础。
  2、细胞产业、基因检测产业的现状和趋势分析
  (1)细胞存储的现状与趋势
  从产业链上来看,干细胞行业的上游为干细胞的采集与存储,中游为干细胞制备及相关干细胞药物的研发,下游为干细胞的治疗应用。
  据国际机构Market Research&Transparency Market Research估计,预计到2018年全球干细胞储存市场容量约181.6亿美元,2015-2018年3年年均复合增长率可达21%。目前全国整体干细胞存储率比例仍不足1%,地区储存率也不平衡,与发达国家相比差距较大。参考发达国家,我国干细胞存储市场预计规模超过300亿,具有较大的市场潜力。
  (2)干细胞临床治疗及产品开发的现状与趋势
  干细胞临床治疗及产品是干细胞产业的发展方向。国际上已有多款干细胞产品或药物获批上市,并且有一大批干细胞治疗临床试验处于III期临床阶段。目前国际上共有10个干细胞产品上市,其中韩国3个,美国2个,比利时1个,澳大利亚1个,加拿大1个,意大利1个,日本1个。
  随着政策的逐步放开,在短时间内已经有十余项干细胞临床研究通过卫计委备案,临床研究治疗的病种涵盖狼疮性肾炎、小儿脑性瘫痪、糖尿病性皮肤病、外伤性脊髓损伤和脊髓小脑性共济失调、心衰等。中国干细胞的临床研究进入高速发展阶段。
  (3)免疫细胞治疗的现状与趋势
  免疫细胞治疗前景广阔,国内外发展十分迅速,我国免疫细胞治疗行业已经从非靶向性的CIK、NK和DC-CIK过渡到CAR-T等靶向性技术。由于我国人口基数大,患病人口数量较多,具有较为优势的临床资源,因此,我国的免疫细胞治疗有望实现弯道超车,达到世界领先的水平。
  美国的免疫细胞研发之路也曾遇到挫折,但这一创新性疗法仍获得FDA的坚定支持。2017年,Cellectis公司宣布其通用型CAR-T疗法UCART123获得了美国FDA的批准,进入临床试验,预计在2017年上半年正式开启1期临床试验。成为第一款获美国FDA批准进入临床试验的基因编辑同种异体CAR-T产品。
  2017年7月12日,FDA肿瘤药物专家咨询委员会一致推荐批准诺华CAR-T疗法Tisagenlecleucel(CTL-019)上市。CTL-019申请的适应症是复发或难治性儿童和年轻成人急性淋巴细胞白血病(ALL),这是PD-1/PD-L1类药物上市近3年后肿瘤免疫治疗领域又一件具有里程碑意义的重磅事件,同时也为其他公司的CAR-T产品上市奠定了基础。
  (4)基因检测行业的现状与趋势
  临床医疗是目前基因测序主要应用领域之一,主要有生殖健康、遗传病检测、新药研发、肿瘤诊断及治疗、心血管疾病以及医学基础研究,其中生殖健康、肿瘤诊断及治疗、新药研发和医学基础研究是目前最主要的应用领域。市场的发展热点也正从无创产前检测技术向肿瘤、心脑血管逐渐过渡。
  肿瘤诊断和治疗应用为基因测序最具潜力的应用市场。《2014年世界癌症报告》数据显示,全球癌症新增病例预计将从2012年的1400万,递增至2025年的1900万,到2035年将达2400万。Illumina公司预测基因测序全球总市场容量为200亿美元,肿瘤诊断与治疗应用方向为120亿美元,占比为60%,是基因测序最大的应用市场。同时,麦肯锡预测基因测序技术在肺癌、肠癌、乳腺癌和前列腺癌等领域的渗透率将高于20%。

  三、报告期内核心竞争力分析
  报告期内,公司核心竞争力未发生重要变化。 收起▲