股本结构
单位：万股
| 公告日期 | 2026-10-08 | 2026-08-05 | 2026-08-05 | 2026-05-06 | 2026-04-23 | 2026-05-06 |
|---|---|---|---|---|---|---|
| 证券总股本 | 15621.78 | 14880.53 | 14478.59 | 14439.77 | 14438.72 | 14431.50 |
| 普通股本 | 15621.78 | 14880.53 | 14478.59 | 14439.77 | 14438.72 | 14431.50 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2026-10-09 | 2026-08-03 | 2026-06-30 | 2026-05-04 | 2026-04-20 | 2026-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2026-10-08 | 15621.78 | 未披露 |
更多>>
Common stock offered 7,412,500 shares by the company
|
2026-10-09 |
| 2026-08-05 | 14880.53 | 未披露 | 定期报告 | 2026-08-03 |
| 2026-08-05 | 14478.59 | 未披露 |
更多>>
From March 31,2026 to June 30,2026
Issuance of common stock in connection with employee incentive plans
|
2026-06-30 |
| 2026-05-06 | 14439.77 | 未披露 | 定期报告 | 2026-05-04 |
| 2026-04-23 | 14438.72 | 未披露 | 定期报告 | 2026-04-20 |
| 2026-05-06 | 14431.50 | 未披露 |
更多>>
From December 31, 2025 to March 31, 2026
Issuance of common stock in connection with employee incentive plans
Issuance of common stock in connection with follow-on public offering, net of commissions and offering expenses of $30,654
|
2026-03-31 |
| 2026-02-24 | 14392.04 | 未披露 | 定期报告 | 2026-02-20 |
| 2026-02-02 | 14370.89 | 未披露 |
更多>>
Common Stock offered 11,000,000 shares by the company
The underwriters exercised their option to purchase common stock 1,650,000 shares
|
2026-02-02 |
| 2026-02-24 | 13105.89 | 未披露 |
更多>>
From December 31, 2024 to December 31, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings
|
2025-12-31 |
| 2025-11-04 | 13090.63 | 未披露 | 定期报告 | 2025-10-31 |
| 2025-11-04 | 13002.91 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with employee incentive plans
|
2025-09-30 |
| 2025-08-06 | 12982.34 | 未披露 | 定期报告 | 2025-08-04 |
| 2025-08-06 | 12981.65 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offering
|
2025-06-30 |
| 2025-05-07 | 12900.41 | 未披露 | 定期报告 | 2025-05-05 |
| 2025-04-28 | 12899.94 | 未披露 | 定期报告 | 2025-04-14 |
| 2025-05-07 | 12893.94 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock and pre-funded warrants in connection with follow-on public offering
|
2025-03-31 |
| 2025-02-25 | 12876.16 | 未披露 | 定期报告 | 2025-02-21 |
| 2025-02-25 | 12489.30 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with employee incentive plans
Issuance of common stock and pre-funded warrants in connection with public follow-on offerings, net of issuance costs of $117,785
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $4,393
|
2024-12-31 |
| 2024-11-05 | 12463.65 | 未披露 | 定期报告 | 2024-11-01 |
| 2024-11-05 | 12442.99 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Release of restricted stock units
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $71,822
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $1,816
|
2024-09-30 |
| 2024-09-05 | 12180.38 | 未披露 |
更多>>
Common stock offered 10,194,175 shares by the company
|
2024-09-06 |
| 2024-08-06 | 11160.97 | 未披露 | 定期报告 | 2024-08-02 |
| 2024-08-06 | 11057.60 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Release of restricted stock units
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $2,551
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
|
2024-06-30 |
| 2024-05-08 | 10879.52 | 未披露 | 定期报告 | 2024-05-06 |
| 2024-04-15 | 10875.94 | 未披露 | 定期报告 | 2024-04-08 |
| 2024-05-08 | 10875.57 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of commissions and offering expenses of $45,997
Release of restricted stock units
|
2024-03-31 |
| 2024-02-27 | 10840.77 | 未披露 | 定期报告 | 2024-02-23 |
| 2024-01-31 | 10609.14 | 未披露 |
更多>>
Common stock offered 10,937,500 shares by the company
|
2024-02-02 |
| 2024-02-27 | 9536.48 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Exercise of stock options
Issuance of common stock in connection with at-the market offering, net of issuance costs of $2,237
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock and pre-funded warrants in connection with public follow -on offerings, net of issuance costs of $29,952
Release of restricted stock units
|
2023-12-31 |
| 2023-11-06 | 9515.39 | 未披露 | 定期报告 | 2023-11-02 |
| 2023-11-06 | 9509.91 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Release of restricted stock units
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,000
|
2023-09-30 |
| 2023-08-08 | 9384.69 | 未披露 | 定期报告 | 2023-08-03 |
| 2023-08-08 | 9381.25 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $29,952
Issuance of common stock under Employee Stock Purchase Plan
Release of restricted stock units
|
2023-06-30 |
| 2023-05-08 | 9370.68 | 未披露 | 定期报告 | 2023-05-04 |
| 2023-04-20 | 9123.37 | 未披露 |
更多>>
Common stock offered 11,200,000 shares by the company
|
2023-04-21 |
| 2023-04-28 | 8064.13 | 未披露 | 定期报告 | 2023-04-17 |
| 2023-05-08 | 8064.09 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,237
Release of restricted stock units
Exercise of stock options
|
2023-03-31 |
| 2023-02-27 | 8003.37 | 未披露 | 定期报告 | 2023-02-23 |
| 2023-02-27 | 7947.07 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock for Sutro stock payment
Issuance of common stock and pre-funded warrants in connection with public follow -on offerings, net of issuance costs of $45,814
Issuance of common stock in connection with at-the market offering, net of issuance costs of $3,107
Release of restricted stock units
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
|
2022-12-31 |
| 2022-12-22 | 7932.08 | 未披露 | 定期报告 | 2022-12-20 |
| 2022-11-07 | 7898.02 | 未披露 | 定期报告 | 2022-11-03 |
| 2022-10-27 | 7431.51 | 未披露 |
更多>>
Common stock offered 15,000,000 shares by the company
|
2022-10-28 |
| 2022-11-07 | 6057.27 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,261
Release of restricted stock units
|
2022-09-30 |
| 2022-08-08 | 5931.51 | 未披露 | 定期报告 | 2022-08-04 |
| 2022-08-08 | 5862.43 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,509
Issuance of common stock under Employee Stock Purchase Plan
|
2022-06-30 |
| 2022-05-09 | 5831.38 | 未披露 | 定期报告 | 2022-05-05 |
| 2022-04-20 | 5805.21 | 未披露 | 定期报告 | 2022-04-11 |
| 2022-05-09 | 5649.95 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $7,376
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $114
|
2022-03-31 |
| 2022-02-28 | 5631.08 | 未披露 | 定期报告 | 2022-02-23 |
| 2022-01-18 | 5508.79 | 未披露 |
更多>>
1.Common stock offered by 2,500,000 shares.
2.The number of shares of common stock that will be outstanding after this offering is based on 52,587,855 shares of common stock outstanding as of September 30, 2021.
|
2022-01-18 |
| 2022-02-28 | 5303.20 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Exercise of stock options
Issuance of common stock to Lonza Ltd.
Issuance of common stock in connection with at-the market offering, net of issuance costs of $479,000
Issuance of common stock under Employee Stock Purchase Plan
|
2021-12-31 |
| 2021-11-10 | 5278.51 | 未披露 | 定期报告 | 2021-11-08 |
| 2021-11-10 | 5258.79 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $41
|
2021-09-30 |
| 2021-08-11 | 5218.93 | 未披露 | 定期报告 | 2021-08-09 |
| 2021-08-11 | 5196.38 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock to Lonza Ltd.
|
2021-06-30 |
| 2021-05-11 | 5137.87 | 未披露 | 定期报告 | 2021-05-07 |
| 2021-04-14 | 5135.45 | 未披露 | 定期报告 | 2021-04-12 |
| 2021-05-11 | 5133.88 | 未披露 |
更多>>
From December 31, 2020 to March 31, 2021
Exercise of stock options
|
2021-03-31 |
| 2021-03-29 | 5132.76 | 未披露 | 定期报告 | 2021-03-25 |
| 2021-03-29 | 5107.16 | 未披露 |
更多>>
from December 31, 2019 to December 31, 2020
Conversion of preferred stock
Issuance of Series D redeemable convertible preferred stock, net of issuance costs of $121
Conversion of common stock warrant
Conversion of preferred stock warrant
Issuance of common stock upon initial public offering, net of issuance costs of $3,368
Exercise of stock options
Issuance of common stock related to early exercised stock options
Issuance of common stock under Employee Stock Purchase Plan
|
2020-12-31 |
| 2020-11-12 | 5094.97 | 未披露 | 定期报告 | 2020-11-11 |
| 2020-11-12 | 5094.95 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Exercise of stock options
|
2020-09-30 |
| 2020-08-12 | 5092.39 | 未披露 | 定期报告 | 2020-08-11 |
| 2020-08-12 | 5088.17 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Conversion of preferred stock
Conversion of common stock warrant
Conversion of preferred stock warrant
Issuance of common stock upon initial public offering, net of issuance costs of $3,296
Exercise of stock options
|
2020-06-30 |
| 2020-06-16 | 5072.95 | 未披露 |
更多>>
On June 16, 2020, the Company completed its initial public offering of 17,968,750 shares of its common stock at a price to the public of $16.00 per share, which includes the full exercise of the underwriters’ option to purchase 2,343,750 additional shares of the Company’s common stock.
|
2020-06-16 |
| 2020-06-15 | 4838.58 | 未披露 |
更多>>
1.Common stock offered by us 15,625,000 shares
|
2020-06-12 |
Common stock offered 7,412,500 shares by the company
From March 31,2026 to June 30,2026
Issuance of common stock in connection with employee incentive plans
From December 31, 2025 to March 31, 2026
Issuance of common stock in connection with employee incentive plans
Issuance of common stock in connection with follow-on public offering, net of commissions and offering expenses of $30,654
Common Stock offered 11,000,000 shares by the company
The underwriters exercised their option to purchase common stock 1,650,000 shares
From December 31, 2024 to December 31, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offerings
From June 30, 2025 to September 30, 2025
Issuance of common stock in connection with employee incentive plans
From March 31, 2025 to June 30, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock from underlying pre-funded warrants in connection with follow-on public offering
From December 31, 2024 to March 31, 2025
Issuance of common stock in connection with employee incentive plans
Issuance of common stock and pre-funded warrants in connection with follow-on public offering
From December 31, 2023 to December 31, 2024
Issuance of common stock in connection with employee incentive plans
Issuance of common stock and pre-funded warrants in connection with public follow-on offerings, net of issuance costs of $117,785
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $4,393
From June 30, 2024 to September 30, 2024
Release of restricted stock units
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $71,822
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $1,816
Common stock offered 10,194,175 shares by the company
From March 31, 2024 to June 30, 2024
Release of restricted stock units
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $2,551
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2023 to March 31, 2024
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of commissions and offering expenses of $45,997
Release of restricted stock units
Common stock offered 10,937,500 shares by the company
From December 31, 2022 to December 31, 2023
Exercise of stock options
Issuance of common stock in connection with at-the market offering, net of issuance costs of $2,237
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock and pre-funded warrants in connection with public follow -on offerings, net of issuance costs of $29,952
Release of restricted stock units
From June 30, 2023 to September 30, 2023
Release of restricted stock units
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,000
From March 31, 2023 to June 30, 2023
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $29,952
Issuance of common stock under Employee Stock Purchase Plan
Release of restricted stock units
Common stock offered 11,200,000 shares by the company
From December 31, 2022 to March 31, 2023
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,237
Release of restricted stock units
Exercise of stock options
From December 31, 2021 to December 31, 2022
Issuance of common stock for Sutro stock payment
Issuance of common stock and pre-funded warrants in connection with public follow -on offerings, net of issuance costs of $45,814
Issuance of common stock in connection with at-the market offering, net of issuance costs of $3,107
Release of restricted stock units
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
Common stock offered 15,000,000 shares by the company
From June 30, 2022 to September 30, 2022
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,261
Release of restricted stock units
From March 31, 2022 to June 30, 2022
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of commissions and offering expenses of $1,509
Issuance of common stock under Employee Stock Purchase Plan
From December 31, 2021 to March 31, 2022
Exercise of stock options
Issuance of common stock and pre-funded warrants in connection with follow-on public offering, net of issuance costs of $7,376
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $114
1.Common stock offered by 2,500,000 shares.
2.The number of shares of common stock that will be outstanding after this offering is based on 52,587,855 shares of common stock outstanding as of September 30, 2021.
From December 31, 2020 to December 31, 2021
Exercise of stock options
Issuance of common stock to Lonza Ltd.
Issuance of common stock in connection with at-the market offering, net of issuance costs of $479,000
Issuance of common stock under Employee Stock Purchase Plan
From June 30, 2021 to September 30, 2021
Exercise of stock options
Issuance of common stock in connection with at-the-market offering, net of issuance costs of $41
From March 31, 2021 to June 30, 2021
Exercise of stock options
Issuance of common stock under Employee Stock Purchase Plan
Issuance of common stock to Lonza Ltd.
From December 31, 2020 to March 31, 2021
Exercise of stock options
from December 31, 2019 to December 31, 2020
Conversion of preferred stock
Issuance of Series D redeemable convertible preferred stock, net of issuance costs of $121
Conversion of common stock warrant
Conversion of preferred stock warrant
Issuance of common stock upon initial public offering, net of issuance costs of $3,368
Exercise of stock options
Issuance of common stock related to early exercised stock options
Issuance of common stock under Employee Stock Purchase Plan
From June 30, 2020 to September 30, 2020
Exercise of stock options
From March 31, 2020 to June 30, 2020
Conversion of preferred stock
Conversion of common stock warrant
Conversion of preferred stock warrant
Issuance of common stock upon initial public offering, net of issuance costs of $3,296
Exercise of stock options
On June 16, 2020, the Company completed its initial public offering of 17,968,750 shares of its common stock at a price to the public of $16.00 per share, which includes the full exercise of the underwriters’ option to purchase 2,343,750 additional shares of the Company’s common stock.
1.Common stock offered by us 15,625,000 shares