股本结构
单位：万股
| 公告日期 | 2025-10-28 | 2025-10-28 | 2025-08-06 | 2025-08-06 | 2025-05-06 | 2025-05-06 |
|---|---|---|---|---|---|---|
| 证券总股本 | 12249.22 | 12028.81 | 11990.51 | 11979.77 | 11920.17 | 11913.78 |
| 普通股本 | 12249.22 | 12028.81 | 11990.51 | 11979.77 | 11920.17 | 11913.78 |
| 优先股 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 其他 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 | 未披露 |
| 变动日期 | 2025-10-22 | 2025-09-30 | 2025-07-31 | 2025-06-30 | 2025-05-01 | 2025-03-31 |
注释：中概股证券总股本=普通股股本/
存托凭证比例
历史变动
| 公告日期 | 变动后普通股本（万股） | 变动后优先股（万股） | 变动原因 | 变动日期 |
|---|---|---|---|---|
| 2025-10-28 | 12249.22 | 未披露 | 定期报告 | 2025-10-22 |
| 2025-10-28 | 12028.81 | 未披露 |
更多>>
From June 30, 2025 to September 30, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2025-09-30 |
| 2025-08-06 | 11990.51 | 未披露 | 定期报告 | 2025-07-31 |
| 2025-08-06 | 11979.77 | 未披露 |
更多>>
From March 31, 2025 to June 30, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the employee stock purchase plan
|
2025-06-30 |
| 2025-05-06 | 11920.17 | 未披露 | 定期报告 | 2025-05-01 |
| 2025-04-29 | 11919.92 | 未披露 | 定期报告 | 2025-04-15 |
| 2025-05-06 | 11913.78 | 未披露 |
更多>>
From December 31, 2024 to March 31, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2025-03-31 |
| 2025-02-25 | 11863.82 | 未披露 | 定期报告 | 2025-02-19 |
| 2025-02-25 | 11784.80 | 未披露 |
更多>>
From December 31, 2023 to December 31, 2024
Shares issued pursuant to the ESPP
Issuance of common stock upon the exercise of stock options
Issuance of common stock and pre-funded warrants, net of issuance costs of $10,820
Issuance of common stock upon the vesting of restricted stock units
|
2024-12-31 |
| 2024-11-06 | 11704.46 | 未披露 | 定期报告 | 2024-11-01 |
| 2024-11-06 | 11699.88 | 未披露 |
更多>>
From June 30, 2024 to September 30, 2024
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2024-09-30 |
| 2024-08-14 | 11689.10 | 未披露 | 定期报告 | 2024-08-09 |
| 2024-08-14 | 11648.03 | 未披露 |
更多>>
From March 31, 2024 to June 30, 2024
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the employee stock purchase plan
|
2024-06-30 |
| 2024-05-14 | 11576.42 | 未披露 | 定期报告 | 2024-05-10 |
| 2024-04-26 | 11552.50 | 未披露 | 定期报告 | 2024-04-22 |
| 2024-05-14 | 11550.54 | 未披露 |
更多>>
From December 31, 2023 to March 31, 2024
Issuance of shares of common stock net of discount and issuance costs of $10,820
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2024-03-31 |
| 2024-03-01 | 11260.28 | 未披露 |
更多>>
Common stock offered 15,789,474 shares by the company
|
2024-03-04 |
| 2024-02-27 | 9681.34 | 未披露 | 定期报告 | 2024-02-21 |
| 2024-02-27 | 9678.73 | 未披露 |
更多>>
From December 31, 2022 to December 31, 2023
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the ESPP
Issuance of common stock from ATM offering, net of issuance costs of $116
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Issuance of common stock and pre-funded warrants, net of issuance costs of $6,546
Issuance of common stock upon the exercise of stock options
|
2023-12-31 |
| 2023-11-03 | 9438.21 | 未披露 | 定期报告 | 2023-10-31 |
| 2023-10-23 | 9415.40 | 未披露 |
更多>>
Common stock offered 32,500,000 shares by the company
|
2023-10-24 |
| 2023-11-03 | 6185.80 | 未披露 |
更多>>
From June 30, 2023 to September 30, 2023
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2023-09-30 |
| 2023-08-08 | 6165.40 | 未披露 | 定期报告 | 2023-08-04 |
| 2023-08-08 | 6163.00 | 未披露 |
更多>>
From March 31, 2023 to June 30, 2023
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
|
2023-06-30 |
| 2023-05-09 | 6142.23 | 未披露 | 定期报告 | 2023-05-04 |
| 2023-04-18 | 6136.09 | 未披露 | 定期报告 | 2023-04-03 |
| 2023-05-09 | 6135.79 | 未披露 |
更多>>
From December 31, 2022 to March 31, 2023
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
|
2023-03-31 |
| 2023-02-28 | 6108.29 | 未披露 | 定期报告 | 2023-02-24 |
| 2023-02-28 | 6103.68 | 未披露 |
更多>>
From December 31, 2021 to December 31, 2022
Issuance of common stock upon the exercise of stock options
Issuance of shares of common stock related to the acquisition of Ducentis Biotherapeutics
Shares issued pursuant to the ESPP
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Issuance of shares of common stock, net of discount and issuance costs of $10,844
Issuance of common stock upon the vesting of restricted stock units
Issuance of shares of common stock under ATM, net of issuance costs of $634
|
2022-12-31 |
| 2022-11-08 | 6092.78 | 未披露 | 定期报告 | 2022-11-04 |
| 2022-11-08 | 6090.86 | 未披露 |
更多>>
From June 30, 2022 to September 30, 2022
Issuance of shares of common stock, net of discount and issuance costs of $10,844
Issuance of shares of common stock related to acquisition of Ducentis Biotherapeutics LTD
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2022-09-30 |
| 2022-08-08 | 6018.75 | 未披露 | 定期报告 | 2022-08-05 |
| 2022-08-04 | 5156.25 | 未披露 | 定期报告 | 2022-07-29 |
| 2022-08-04 | 5152.62 | 未披露 |
更多>>
From March 31, 2022 to June 30, 2022
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
|
2022-06-30 |
| 2022-04-19 | 5141.80 | 未披露 | 定期报告 | 2022-04-04 |
| 2022-05-05 | 5136.03 | 未披露 |
更多>>
From December 31, 2021 to March 31, 2022
Issuance of shares of common stock under ATM, net of issuance costs of $634
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2022-03-31 |
| 2022-02-22 | 5038.03 | 未披露 | 定期报告 | 2022-02-16 |
| 2022-02-22 | 5025.56 | 未披露 |
更多>>
From December 31, 2020 to December 31, 2021
Issuance of shares of common stock for public offering, net of issuance costs of $603
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
|
2021-12-31 |
| 2021-11-04 | 5029.53 | 未披露 | 定期报告 | 2021-10-29 |
| 2021-11-04 | 5013.48 | 未披露 |
更多>>
From June 30, 2021 to September 30, 2021
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2021-09-30 |
| 2021-08-05 | 5024.18 | 未披露 | 定期报告 | 2021-07-30 |
| 2021-08-05 | 5004.56 | 未披露 |
更多>>
From March 31, 2021 to June 30, 2021
Issuance of shares of common stock upon the exercise of stock options
Shares issued pursuant to the employee stock purchase plan
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2021-06-30 |
| 2021-05-06 | 5020.50 | 未披露 | 定期报告 | 2021-04-30 |
| 2021-04-27 | 5014.97 | 未披露 | 定期报告 | 2021-04-13 |
| 2021-05-06 | 4988.70 | 未披露 |
更多>>
from December 31, 2020 to March 31, 2021
Issuance of shares of common stock for public offering, net of issuance costs of $603
Issuance of shares of common stock upon the exercise of stock options
Issuance of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2021-03-31 |
| 2021-02-16 | 5008.47 | 未披露 | 定期报告 | 2021-02-11 |
| 2021-02-05 | 4869.89 | 未披露 |
更多>>
1.Common stock offered by the company 5,500,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 43,198,889 shares of common stock outstanding as of September 30, 2020 (after giving effect to the issuance of an aggregate of 5,400,000 shares of common stock in an underwritten public offering and concurrent private placement in October 2020).
|
2021-02-05 |
| 2021-02-01 | 4371.94 | 未披露 | 定期报告 | 2021-01-26 |
| 2021-02-16 | 4367.78 | 未披露 |
更多>>
From December 31,2019 to December 31,2020
Conversion of preferred stock into common stock upon initial public offering
Issuance of shares of common stock for initial public offering, net of issuance costs of $16,040,000
Issuance of shares of common stock for public offering, net of issuance costs of $6,640,000
Issuance of shares of common stock for private placement
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
|
2020-12-31 |
| 2020-11-05 | 4363.45 | 未披露 | 定期报告 | 2020-10-31 |
| 2020-10-06 | 4309.01 | 未披露 |
更多>>
1.Common stock offered by the company 4,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering and the concurrent private placement is based on 37,690,058 shares of common stock outstanding as of June 30, 2020.
|
2020-10-06 |
| 2020-11-05 | 3779.89 | 未披露 |
更多>>
From June 30, 2020 to September 30, 2020
Issuance of common stock upon the exercise of stock options
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2020-09-30 |
| 2020-08-11 | 3818.93 | 未披露 | 定期报告 | 2020-08-01 |
| 2020-08-11 | 3769.01 | 未披露 |
更多>>
From March 31, 2020 to June 30, 2020
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
|
2020-06-30 |
| 2020-05-12 | 3815.46 | 未披露 | 定期报告 | 2020-05-01 |
| 2020-05-12 | 3747.20 | 未披露 |
更多>>
From December 31, 2019 to March 31, 2020
Conversion of preferred stock into common stock upon initial public offering
Issuance of shares of common stock, net of issuance costs of $16.0 million
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2020-03-31 |
| 2020-03-19 | 3808.90 | 未披露 | 定期报告 | 2020-03-01 |
| 2020-01-31 | 3662.69 | 未披露 |
更多>>
1.Common stock offered 9,375,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 27,251,906 shares of our common stock outstanding as of September 30, 2019
|
2020-01-31 |
| 2020-03-19 | 212.09 | 2438.54 |
更多>>
from December 31, 2018 to December 31, 2019
Issuance of Series C convertible preferred stock, net of issuance costs of $262
Issuance of common stock upon the exercise of stock options
Issuance of restricted stock units
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
|
2019-12-31 |
From June 30, 2025 to September 30, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
From March 31, 2025 to June 30, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the employee stock purchase plan
From December 31, 2024 to March 31, 2025
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
From December 31, 2023 to December 31, 2024
Shares issued pursuant to the ESPP
Issuance of common stock upon the exercise of stock options
Issuance of common stock and pre-funded warrants, net of issuance costs of $10,820
Issuance of common stock upon the vesting of restricted stock units
From June 30, 2024 to September 30, 2024
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
From March 31, 2024 to June 30, 2024
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the employee stock purchase plan
From December 31, 2023 to March 31, 2024
Issuance of shares of common stock net of discount and issuance costs of $10,820
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Common stock offered 15,789,474 shares by the company
From December 31, 2022 to December 31, 2023
Issuance of common stock upon the vesting of restricted stock units
Shares issued pursuant to the ESPP
Issuance of common stock from ATM offering, net of issuance costs of $116
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Issuance of common stock and pre-funded warrants, net of issuance costs of $6,546
Issuance of common stock upon the exercise of stock options
Common stock offered 32,500,000 shares by the company
From June 30, 2023 to September 30, 2023
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
From March 31, 2023 to June 30, 2023
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
From December 31, 2022 to March 31, 2023
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
From December 31, 2021 to December 31, 2022
Issuance of common stock upon the exercise of stock options
Issuance of shares of common stock related to the acquisition of Ducentis Biotherapeutics
Shares issued pursuant to the ESPP
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Issuance of shares of common stock, net of discount and issuance costs of $10,844
Issuance of common stock upon the vesting of restricted stock units
Issuance of shares of common stock under ATM, net of issuance costs of $634
From June 30, 2022 to September 30, 2022
Issuance of shares of common stock, net of discount and issuance costs of $10,844
Issuance of shares of common stock related to acquisition of Ducentis Biotherapeutics LTD
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
From March 31, 2022 to June 30, 2022
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
From December 31, 2021 to March 31, 2022
Issuance of shares of common stock under ATM, net of issuance costs of $634
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
From December 31, 2020 to December 31, 2021
Issuance of shares of common stock for public offering, net of issuance costs of $603
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchasing rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
From June 30, 2021 to September 30, 2021
Issuance of common stock upon the exercise of stock options
Issuance of common stock upon the vesting of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
From March 31, 2021 to June 30, 2021
Issuance of shares of common stock upon the exercise of stock options
Shares issued pursuant to the employee stock purchase plan
Lapse of repurchase rights related to common stock issued pursuant to early exercises
from December 31, 2020 to March 31, 2021
Issuance of shares of common stock for public offering, net of issuance costs of $603
Issuance of shares of common stock upon the exercise of stock options
Issuance of restricted stock units
Lapse of repurchase rights related to common stock issued pursuant to early exercises
1.Common stock offered by the company 5,500,000 shares.
2.The number of shares of common stock to be outstanding after this offering is based on 43,198,889 shares of common stock outstanding as of September 30, 2020 (after giving effect to the issuance of an aggregate of 5,400,000 shares of common stock in an underwritten public offering and concurrent private placement in October 2020).
From December 31,2019 to December 31,2020
Conversion of preferred stock into common stock upon initial public offering
Issuance of shares of common stock for initial public offering, net of issuance costs of $16,040,000
Issuance of shares of common stock for public offering, net of issuance costs of $6,640,000
Issuance of shares of common stock for private placement
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
1.Common stock offered by the company 4,000,000 shares.
2.The number of shares of common stock to be outstanding after this offering and the concurrent private placement is based on 37,690,058 shares of common stock outstanding as of June 30, 2020.
From June 30, 2020 to September 30, 2020
Issuance of common stock upon the exercise of stock options
Lapse of repurchase rights related to common stock issued pursuant to early exercises
From March 31, 2020 to June 30, 2020
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
Shares issued pursuant to the employee stock purchase plan
From December 31, 2019 to March 31, 2020
Conversion of preferred stock into common stock upon initial public offering
Issuance of shares of common stock, net of issuance costs of $16.0 million
Issuance of common stock upon the exercise of stock options
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises
1.Common stock offered 9,375,000 shares
2.The number of shares of our common stock to be outstanding after this offering is based on 27,251,906 shares of our common stock outstanding as of September 30, 2019
from December 31, 2018 to December 31, 2019
Issuance of Series C convertible preferred stock, net of issuance costs of $262
Issuance of common stock upon the exercise of stock options
Issuance of restricted stock units
Vesting of founder shares subject to repurchase
Lapse of repurchase rights related to common stock issued pursuant to early exercises